(8 nodes) Plasma membrane respiratory chain complex I network (Chlorobaculum tepidum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ndhI	NADH dehydrogenase I, 23 kDA subunit; Identified by similarity to EGAD:12904; similarity to EGAD:162929; match to protein family HMM PF00037. (216 aa)
	ndhD	NADH dehydrogenase I, subunit 4; Identified by similarity to EGAD:42981; match to protein family HMM PF00361; match to protein family HMM TIGR01972. (545 aa)
	CT1260	Ferredoxin, 4Fe-4S; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (62 aa)
	CT1261	Ferredoxin, 4Fe-4S; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (62 aa)
	CT1736	Ferredoxin, 4Fe-4S; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (62 aa)
	pscB	Photosystem P840 reaction center iron-sulfur protein; Identified by similarity to EGAD:33793; match to protein family HMM PF00037. (231 aa)
	ndhH	NADH dehydrogenase I, 20 kdA subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (189 aa)
	CT0167	Conserved hypothetical protein; Identified by similarity to EGAD:106863; match to protein family HMM PF00037. (87 aa)

Your Current Organism:

Chlorobaculum tepidum

NCBI taxonomy Id: 194439
Other names: C. tepidum TLS, Chlorobaculum tepidum TLS, Chlorobium tepidum TLS

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CT0167	ndhD	CT0167	CT0775	Conserved hypothetical protein; Identified by similarity to EGAD:106863; match to protein family HMM PF00037.	NADH dehydrogenase I, subunit 4; Identified by similarity to EGAD:42981; match to protein family HMM PF00361; match to protein family HMM TIGR01972.	0.833
CT0167	ndhH	CT0167	CT0767	Conserved hypothetical protein; Identified by similarity to EGAD:106863; match to protein family HMM PF00037.	NADH dehydrogenase I, 20 kdA subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	0.859
CT1260	CT1261	CT1260	CT1261	Ferredoxin, 4Fe-4S; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.	Ferredoxin, 4Fe-4S; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.	0.472
CT1260	ndhD	CT1260	CT0775	Ferredoxin, 4Fe-4S; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.	NADH dehydrogenase I, subunit 4; Identified by similarity to EGAD:42981; match to protein family HMM PF00361; match to protein family HMM TIGR01972.	0.833
CT1260	ndhH	CT1260	CT0767	Ferredoxin, 4Fe-4S; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.	NADH dehydrogenase I, 20 kdA subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	0.859
CT1261	CT1260	CT1261	CT1260	Ferredoxin, 4Fe-4S; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.	Ferredoxin, 4Fe-4S; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.	0.472
CT1261	ndhD	CT1261	CT0775	Ferredoxin, 4Fe-4S; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.	NADH dehydrogenase I, subunit 4; Identified by similarity to EGAD:42981; match to protein family HMM PF00361; match to protein family HMM TIGR01972.	0.833
CT1261	ndhH	CT1261	CT0767	Ferredoxin, 4Fe-4S; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.	NADH dehydrogenase I, 20 kdA subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	0.859
CT1736	ndhD	CT1736	CT0775	Ferredoxin, 4Fe-4S; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.	NADH dehydrogenase I, subunit 4; Identified by similarity to EGAD:42981; match to protein family HMM PF00361; match to protein family HMM TIGR01972.	0.833
CT1736	ndhH	CT1736	CT0767	Ferredoxin, 4Fe-4S; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.	NADH dehydrogenase I, 20 kdA subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	0.859
ndhD	CT0167	CT0775	CT0167	NADH dehydrogenase I, subunit 4; Identified by similarity to EGAD:42981; match to protein family HMM PF00361; match to protein family HMM TIGR01972.	Conserved hypothetical protein; Identified by similarity to EGAD:106863; match to protein family HMM PF00037.	0.833
ndhD	CT1260	CT0775	CT1260	NADH dehydrogenase I, subunit 4; Identified by similarity to EGAD:42981; match to protein family HMM PF00361; match to protein family HMM TIGR01972.	Ferredoxin, 4Fe-4S; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.	0.833
ndhD	CT1261	CT0775	CT1261	NADH dehydrogenase I, subunit 4; Identified by similarity to EGAD:42981; match to protein family HMM PF00361; match to protein family HMM TIGR01972.	Ferredoxin, 4Fe-4S; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.	0.833
ndhD	CT1736	CT0775	CT1736	NADH dehydrogenase I, subunit 4; Identified by similarity to EGAD:42981; match to protein family HMM PF00361; match to protein family HMM TIGR01972.	Ferredoxin, 4Fe-4S; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.	0.833
ndhD	ndhH	CT0775	CT0767	NADH dehydrogenase I, subunit 4; Identified by similarity to EGAD:42981; match to protein family HMM PF00361; match to protein family HMM TIGR01972.	NADH dehydrogenase I, 20 kdA subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	0.999
ndhD	ndhI	CT0775	CT0771	NADH dehydrogenase I, subunit 4; Identified by similarity to EGAD:42981; match to protein family HMM PF00361; match to protein family HMM TIGR01972.	NADH dehydrogenase I, 23 kDA subunit; Identified by similarity to EGAD:12904; similarity to EGAD:162929; match to protein family HMM PF00037.	0.996
ndhD	pscB	CT0775	CT2019	NADH dehydrogenase I, subunit 4; Identified by similarity to EGAD:42981; match to protein family HMM PF00361; match to protein family HMM TIGR01972.	Photosystem P840 reaction center iron-sulfur protein; Identified by similarity to EGAD:33793; match to protein family HMM PF00037.	0.833
ndhH	CT0167	CT0767	CT0167	NADH dehydrogenase I, 20 kdA subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	Conserved hypothetical protein; Identified by similarity to EGAD:106863; match to protein family HMM PF00037.	0.859
ndhH	CT1260	CT0767	CT1260	NADH dehydrogenase I, 20 kdA subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	Ferredoxin, 4Fe-4S; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.	0.859
ndhH	CT1261	CT0767	CT1261	NADH dehydrogenase I, 20 kdA subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	Ferredoxin, 4Fe-4S; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.	0.859