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| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (222 aa) |
| | bchU | C-20 methyltransferase; Involved in the biosynthesis of the major light-harvesting pigment bacteriochlorophyll c (BChlc), which confers a significant competitive advantage to green sulfur bacteria living at limiting red and near-infrared light intensities. Catalyzes the methylation at the C-20 position of the cyclic tetrapyrrole chlorin of bacteriochlorophyll d (BChld) to produce bacteriochlorophyll c (BChlc) using S-adenosylmethionine (SAM) as a methyl source. (338 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (266 aa) |
| | tyrA | Prephenate dehydrogenase; Identified by similarity to EGAD:8704; match to protein family HMM PF02153; match to protein family HMM PF03446. (288 aa) |
| | gpsA | Glycerol-3-phosphate dehydrogenase, NAD-dependent; Identified by similarity to EGAD:8708; match to protein family HMM PF01210; match to protein family HMM PF03446; match to protein family HMM PF07479; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (333 aa) |
| | plsY | Membrane protein, putative; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (232 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase; Identified by similarity to EGAD:24860; match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR00878. (329 aa) |
| | lysC | Aspartokinase; Identified by similarity to EGAD:9629; match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00657; Belongs to the aspartokinase family. (470 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (382 aa) |
| | eno-2 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (437 aa) |
| | gcpE | gcpE protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (746 aa) |
| | accC | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa) |
| | accB | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (157 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (334 aa) |
| | CT0162 | Alpha oxoglutarate ferredoxin oxidoreductase, beta subunit; Identified by similarity to EGAD:144641; match to protein family HMM PF02775. (342 aa) |
| | CT0163 | Alpha oxoglutarate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to EGAD:144640; match to protein family HMM PF01558; match to protein family HMM PF01855. (627 aa) |
| | serB | Phosphoserine phosphatase; Identified by similarity to EGAD:8936; match to protein family HMM PF00702; match to protein family HMM PF01842; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488. (407 aa) |
| | trpB-2 | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (458 aa) |
| | cdsA | Phosphatidate cytidylyltransferase; Identified by similarity to EGAD:49693; match to protein family HMM PF01148; Belongs to the CDS family. (273 aa) |
| | ribF | Riboflavin biosynthesis protein RibF; Identified by similarity to EGAD:91083; match to protein family HMM PF01687; match to protein family HMM PF06574; match to protein family HMM TIGR00083; Belongs to the ribF family. (321 aa) |
| | pfk-2 | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (390 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (128 aa) |
| | CT0256 | Isoprenyl synthetase; Identified by similarity to EGAD:105518; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. (332 aa) |
| | fni | Isopentenyl-diphosphate delta-isomerase, putative; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (357 aa) |
| | CT0260 | Identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880. (476 aa) |
| | uppS | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (265 aa) |
| | sucD | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (300 aa) |
| | CT0282 | Glutamate synthase, small subunit, putative; Identified by similarity to EGAD:37434; match to protein family HMM PF00070; match to protein family HMM PF07992. (582 aa) |
| | lytB | Penicillin tolerance protein LytB; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (332 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (503 aa) |
| | crtC | Hydroxyneurosporene synthase CrtC; Identified by similarity to EGAD:131985; match to protein family HMM PF07143; Belongs to the CrtC hydratase family. (382 aa) |
| | rfbA | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (293 aa) |
| | rfbC | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (185 aa) |
| | rfbD | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (292 aa) |
| | rfbB | dTDP-D-glucose 4,6-dehydratase; Identified by similarity to EGAD:37484; match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM TIGR01181; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (349 aa) |
| | CT0309 | Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl transferase; Identified by similarity to EGAD:20531; match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; Belongs to the mannose-6-phosphate isomerase type 2 family. (470 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (497 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (199 aa) |
| | purH | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Identified by similarity to EGAD:22140; match to protein family HMM PF01808; match to protein family HMM PF02142; match to protein family HMM TIGR00355. (523 aa) |
| | dxs | 1-deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (644 aa) |
| | fabI | Enoyl-(acyl-carrier-protein) reductase; Identified by similarity to EGAD:14980; match to protein family HMM PF00106. (293 aa) |
| | icd | Isocitrate dehydrogenase, NADP-dependent, monomeric type; Identified by similarity to EGAD:40125; match to protein family HMM PF03971; match to protein family HMM TIGR00178; Belongs to the monomeric-type IDH family. (741 aa) |
| | fbp | Fructose-1,6-bisphosphatase; Identified by similarity to EGAD:7884; match to protein family HMM PF00316. (333 aa) |
| | argD | Acetylornithine aminotransferase; Identified by similarity to EGAD:102397; match to protein family HMM PF00202; match to protein family HMM TIGR00707; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (400 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (175 aa) |
| | hemN | Oxygen-independent coproporphyrinogen III oxidase; Identified by match to protein family HMM PF04055; match to protein family HMM PF06969; match to protein family HMM TIGR00538; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (476 aa) |
| | sucC | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (392 aa) |
| | cobA | uroporphyrin-III C-methyltransferase; Identified by similarity to EGAD:12949; match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family. (267 aa) |
| | gpm | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (247 aa) |
| | gltB | Glutamate synthase, large subunit; Identified by similarity to EGAD:109137; similarity to EGAD:134205; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04897; match to protein family HMM PF04898. (1538 aa) |
| | gltD-2 | Glutamate synthase, small subunit; Identified by similarity to EGAD:142506; match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01317. (490 aa) |
| | CT0420 | Magnesium-chelatase, subunit D/I family; Identified by similarity to EGAD:134942; match to protein family HMM PF00092; match to protein family HMM PF01078; match to protein family HMM TIGR02442. (649 aa) |
| | CT0421 | Identified by similarity to EGAD:49433; match to protein family HMM PF01078. (347 aa) |
| | CT0456 | Conserved hypothetical protein; Identified by similarity to EGAD:47444. (512 aa) |
| | menG | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (242 aa) |
| | hisI | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (137 aa) |
| | gltD-1 | Glutamate synthase, small subunit; Identified by similarity to EGAD:37434; match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01316. (472 aa) |
| | hisH | Amidotransferase HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (201 aa) |
| | hisA | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Identified by similarity to GP:6175607; match to protein family HMM PF00977; match to protein family HMM TIGR00007. (260 aa) |
| | trpB-1 | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (400 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (267 aa) |
| | MetK | S-adenosylmethionine synthase, archaeal-type; Identified by similarity to EGAD:171913; match to protein family HMM PF01941. (404 aa) |
| | acn | Aconitate hydratase; Identified by similarity to EGAD:8034; match to protein family HMM PF00330; match to protein family HMM PF06434; match to protein family HMM TIGR00117; Belongs to the aconitase/IPM isomerase family. (854 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (428 aa) |
| | met2 | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (356 aa) |
| | leuA-1 | 2-isopropylmalate synthase; Identified by similarity to EGAD:32071; match to protein family HMM PF00682; match to protein family HMM TIGR00977; Belongs to the alpha-IPM synthase/homocitrate synthase family. (534 aa) |
| | CT0613 | 3-isopropylmalate dehydratase, small subunit, putative; Identified by match to protein family HMM PF00694; match to protein family HMM TIGR02087; Belongs to the LeuD family. (190 aa) |
| | CT0614 | 3-isopropylmalate dehydratase, large subunit, putative; Identified by match to protein family HMM PF00330; match to protein family HMM TIGR01343; match to protein family HMM TIGR02086; Belongs to the aconitase/IPM isomerase family. (431 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. (352 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (330 aa) |
| | ilvN | Acetolactate synthase, small subunit; Identified by similarity to GP:5733116; match to protein family HMM PF01842; match to protein family HMM TIGR00119. (159 aa) |
| | ilvB | Acetolactate synthase, large subunit; Identified by similarity to EGAD:156267; match to protein family HMM PF00205; match to protein family HMM PF02776; match to protein family HMM TIGR00118. (573 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Identified by similarity to SP:P51785; match to protein family HMM PF00920; match to protein family HMM TIGR00110; Belongs to the IlvD/Edd family. (560 aa) |
| | CT0649 | Carotenoid isomerase, putative; Identified by similarity to GP:3820561; match to protein family HMM PF01593; match to protein family HMM PF07992. (500 aa) |
| | cysK | Cysteine synthase; Identified by similarity to EGAD:101752; match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139. (310 aa) |
| | CT0701 | Identified by match to protein family HMM PF01053. (380 aa) |
| | trpF | N-(5'-phosphoribosyl)-anthranilate isomerase; Identified by similarity to EGAD:38562; match to protein family HMM PF00697; Belongs to the TrpF family. (221 aa) |
| | metK | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (376 aa) |
| | CT0727 | Glucose-1-phosphate thymidylyltransferase, putative; Identified by similarity to EGAD:51323; match to protein family HMM PF00483. (325 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase; Identified by similarity to SP:P06987; match to protein family HMM PF00475. (194 aa) |
| | ribD | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (373 aa) |
| | ribE | Riboflavin synthase, alpha subunit; Identified by similarity to EGAD:14904; match to protein family HMM PF00677; match to protein family HMM TIGR00187. (219 aa) |
| | CT0804 | Transketolase, C-terminal subunit; Identified by match to protein family HMM PF02779; match to protein family HMM PF02780. (327 aa) |
| | CT0807 | Phytoene desaturase; Identified by similarity to GP:5911761; match to protein family HMM PF01593. (465 aa) |
| | fumA | Fumarate hydratase, class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (503 aa) |
| | sat | Sulfate adenylyltransferase; Identified by similarity to GP:3551262; match to protein family HMM PF01747; match to protein family HMM TIGR00339; Belongs to the sulfate adenylyltransferase family. (404 aa) |
| | gph | Phosphoglycolate phosphatase; Identified by similarity to EGAD:8531; match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549. (225 aa) |
| | CT0892 | Conserved hypothetical protein; Identified by similarity to GP:3080493; match to protein family HMM PF01553. (185 aa) |
| | CT0939 | Aminotransferase, class II; Identified by match to protein family HMM PF00155. (369 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Identified by similarity to EGAD:19545; match to protein family HMM PF01259; match to protein family HMM TIGR00081; Belongs to the SAICAR synthetase family. (235 aa) |
| | CT0963 | Transketolase, N-terminal subunit; Identified by match to protein family HMM PF00456. (303 aa) |
| | CT0966 | Aspartate aminotransferase, putative; Catalyzes the reversible conversion of aspartate and 2- oxoglutarate to glutamate and oxaloacetate. Can also transaminate prephenate in the presence of aspartate. (400 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (329 aa) |
| | aroF | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (353 aa) |
| | pgi | Glucose-6-phosphate isomerase; Identified by similarity to EGAD:62754; match to protein family HMM PF00342. (559 aa) |
| | purB | Adenylosuccinate lyase; Identified by similarity to EGAD:15453; match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (434 aa) |
| | rpiB | Ribose-5-phosphate isomerase; Identified by similarity to EGAD:16338; match to protein family HMM PF02502; match to protein family HMM TIGR00689; match to protein family HMM TIGR01120. (144 aa) |
| | fbaA | Fructose-bisphosphate aldolase, class II; Identified by similarity to EGAD:43086; match to protein family HMM PF01116; match to protein family HMM TIGR00167; match to protein family HMM TIGR01859. (323 aa) |
| | argH | Argininosuccinate lyase; Identified by similarity to EGAD:11709; match to protein family HMM PF00206; match to protein family HMM TIGR00838. (463 aa) |
| | purT | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (392 aa) |
| | CT1063 | Conserved hypothetical protein; Identified by similarity to EGAD:76752; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF05368; match to protein family HMM PF07993. (344 aa) |
| | CT1077 | Hypothetical protein; Identified by Glimmer2; putative. (193 aa) |
| | CT1088 | Citrate lyase, subunit2; Identified by similarity to GP:4107343; match to protein family HMM PF00549; match to protein family HMM PF02629. (610 aa) |
| | CT1089 | Citrate lyase, subunit1; Identified by similarity to EGAD:63655. (398 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (341 aa) |
| | argJ | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (404 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (285 aa) |
| | argF | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (338 aa) |
| | argG | Argininosuccinate synthase; Identified by similarity to EGAD:39789; match to protein family HMM PF00764; match to protein family HMM TIGR00032; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (401 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (218 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (148 aa) |
| | CT1206 | Polyprenyl synthetase; Identified by similarity to EGAD:40622; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. (324 aa) |
| | CT1236 | Phosphatase, putative; Identified by similarity to GP:9757183. (139 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (759 aa) |
| | hisC | Histidinol-phosphate aminotransferase; Identified by similarity to EGAD:10126; similarity to EGAD:156515; match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (348 aa) |
| | chlG | Bacteriochlorophyll synthase, 34 kDa subunit; Identified by similarity to SP:P33326; match to protein family HMM PF01040; match to protein family HMM TIGR01476. (367 aa) |
| | CT1275 | Alcohol dehydrogenase, zinc-containing; Identified by similarity to GP:2708273. (338 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (494 aa) |
| | bchH-3 | Magnesium-protoporphyrin methyltransferase; Identified by similarity to GP:2661856; match to protein family HMM PF02514; match to protein family HMM TIGR02025. (1271 aa) |
| | bchD | Magnesium-chelatase, subunit D; Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. (620 aa) |
| | bchI | Magnesium-chelatase, subunit I; Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. (392 aa) |
| | lpd-1 | Dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (469 aa) |
| | ispD | 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (246 aa) |
| | bchR | BchE/P-methylase family protein; Involved in the biosynthesis of the major light-harvesting pigment bacteriochlorophyll c (BChlc), which confers a significant competitive advantage to green sulfur bacteria living at limiting red and near-infrared light intensities. BchR is a methyltransferase that adds a single methyl group to the methyl carbon at the C-12(1) position of 8-ethyl-12-methyl-3-vinylbacteriochlorophyllide d to yield 8,12- diethyl-3-vinylbacteriochlorophyllide d; Belongs to the radical SAM superfamily. (456 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (234 aa) |
| | purS | Conserved hypothetical protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer [...] (84 aa) |
| | pssA | CDP-diacylglycerol--serine O-phosphatidyltransferase; Identified by similarity to EGAD:89668; match to protein family HMM PF01066; match to protein family HMM TIGR00473; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (266 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (277 aa) |
| | prsA | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (323 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (416 aa) |
| | CT1386 | Phytoene desaturase; Identified by similarity to EGAD:49612; match to protein family HMM PF00494. (310 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (191 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (368 aa) |
| | CT1414 | Zeta-carotene desaturase; Identified by similarity to EGAD:49382; match to protein family HMM PF01593. (453 aa) |
| | bchF | 2-vinyl bacteriochlorophyllide hydratase; Identified by similarity to EGAD:8942; match to protein family HMM PF07284; match to protein family HMM TIGR02020. (158 aa) |
| | bchC | 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase; Identified by similarity to EGAD:9474; match to protein family HMM PF00107; match to protein family HMM TIGR01202. (337 aa) |
| | bchX | Chlorophyllide reductase, BchX subunit; Identified by similarity to EGAD:10210; match to protein family HMM PF00142; match to protein family HMM TIGR02016; Belongs to the NifH/BchL/ChlL family. (384 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (426 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (312 aa) |
| | hemD | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (246 aa) |
| | hemB | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. (328 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (397 aa) |
| | cysE | Serine acetyltransferase; Identified by similarity to EGAD:8839; similarity to EGAD:9562; match to protein family HMM PF00132; match to protein family HMM PF06426; match to protein family HMM TIGR01172. (273 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (245 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (504 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (361 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (420 aa) |
| | gapA | Glyceraldehyde 3-phosphate dehydrogenase; Identified by similarity to EGAD:13804; match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa) |
| | ispE | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (286 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (310 aa) |
| | CT1509 | CAAX prenyl protease 1, putative; Identified by similarity to EGAD:53859; match to protein family HMM PF01435. (415 aa) |
| | menA | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (307 aa) |
| | hisF | hisF protein (cyclase); IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (251 aa) |
| | gpt | Hypoxanthine-guanine phosphoribosyltransferase; Identified by similarity to GP:3046326; match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (176 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (278 aa) |
| | surE | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (263 aa) |
| | pabA | Para-aminobenzoate/anthranilate synthase glutamine amidotransferase; Identified by similarity to EGAD:15632; match to protein family HMM PF00117; match to protein family HMM TIGR00566. (187 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (440 aa) |
| | ribBA | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (427 aa) |
| | CT1596 | Identified by similarity to EGAD:156316; match to protein family HMM PF00343; match to protein family HMM TIGR02094. (707 aa) |
| | ispF | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (157 aa) |
| | pfk-1 | Phosphofructokinase; Identified by similarity to SP:O08333; match to protein family HMM PF00365. (401 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (303 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (351 aa) |
| | bchG | Bacteriochlorophyll synthase, 34 kDa subunit; Identified by similarity to SP:P33326; match to protein family HMM PF01040; match to protein family HMM TIGR01476. (330 aa) |
| | psd | Conserved hypothetical protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (216 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (296 aa) |
| | gcvP1 | Glycine cleavage system P protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (444 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa) |
| | nifJ | Pyruvate flavodoxin/ferrodoxin oxidoreductase; Identified by similarity to EGAD:9985; match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM PF02775; match to protein family HMM TIGR02176. (1185 aa) |
| | panC | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (284 aa) |
| | acs | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (621 aa) |
| | suhB | Extragenic suppressor protein SuhB; Identified by similarity to EGAD:15335; match to protein family HMM PF00459; Belongs to the inositol monophosphatase superfamily. (264 aa) |
| | pheA | Prephenate dehydratase; Identified by similarity to EGAD:20539; match to protein family HMM PF00800; match to protein family HMM PF01842. (280 aa) |
| | rpe | Ribulose-phosphate 3-epimerase; Identified by similarity to EGAD:101737; match to protein family HMM PF00215; match to protein family HMM PF00834; match to protein family HMM TIGR01163; Belongs to the ribulose-phosphate 3-epimerase family. (220 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Identified by similarity to EGAD:15617; match to protein family HMM PF00218; Belongs to the TrpC family. (256 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Identified by similarity to EGAD:7937; match to protein family HMM PF01071; match to protein family HMM PF02842; match to protein family HMM PF02843; match to protein family HMM PF02844; match to protein family HMM TIGR00877. (425 aa) |
| | ppd | Pyruvate,orthophosphate dikinase; Identified by similarity to EGAD:140591; match to protein family HMM PF00391; match to protein family HMM PF01326; match to protein family HMM PF02896; match to protein family HMM TIGR01828; Belongs to the PEP-utilizing enzyme family. (915 aa) |
| | CT1763 | uroporphyrin-III C-methyltransferase; Identified by similarity to EGAD:6870; match to protein family HMM PF00590. (300 aa) |
| | rbcL | Ribulose bisphosphate carboxylase, large subunit; May be involved in sulfur metabolism and oxidative stress response. Does not show RuBisCO activity; Belongs to the RuBisCO large chain family. Type IV subfamily. (435 aa) |
| | CT1776 | Bacteriochlorophyll c3(1) hydratase; Identified by similarity to EGAD:8942; match to protein family HMM PF07284; match to protein family HMM TIGR02020. (190 aa) |
| | bchQ | Bacteriochlorophyll c8 methyltransferase; Involved in the biosynthesis of the major light-harvesting pigment bacteriochlorophyll c (BChlc), which confers a significant competitive advantage to green sulfur bacteria living at limiting red and near-infrared light intensities. BchQ is a methyltransferase that adds two consecutive methyl groups to the ethyl carbon at the C-8(2) position of 8,12-diethyl-3-vinylbacteriochlorophyllide d to yield 12- ethyl-8-isobutyl-3-vinylbacteriochlorophyllide d. (451 aa) |
| | gcvT | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (365 aa) |
| | aroE | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (295 aa) |
| | deoD | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (273 aa) |
| | bchY | Chlorophyllide reductase, BchY subunit; Identified by similarity to EGAD:10229; match to protein family HMM PF00148; match to protein family HMM TIGR02015. (407 aa) |
| | gltA | Citrate synthase; Identified by similarity to EGAD:20399; similarity to EGAD:77210; match to protein family HMM PF00285; match to protein family HMM TIGR01798; Belongs to the citrate synthase family. (447 aa) |
| | menF | Menaquinone-specific isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. (488 aa) |
| | menD | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). (601 aa) |
| | menH | Thioesterase, menaquinone synthesis gene; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). (275 aa) |
| | menB | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). (293 aa) |
| | menC | o-succinylbenzoate-CoA synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (363 aa) |
| | menE | O-succinylbenzoic acid--CoA ligase; Identified by similarity to EGAD:15476; match to protein family HMM PF00501; match to protein family HMM TIGR01923. (458 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (249 aa) |
| | metH | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1228 aa) |
| | tkt | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (688 aa) |
| | pgl | Oxidoreductase, Sol/DevB family; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (267 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (479 aa) |
| | CT1874 | 6-phosphogluconate dehydrogenase, decarboxylating, putative; Identified by similarity to EGAD:13295; match to protein family HMM PF00393; match to protein family HMM PF03446; match to protein family HMM TIGR00872. (295 aa) |
| | aldA | Aldehyde dehydrogenase; Identified by similarity to EGAD:4728; match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (460 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (434 aa) |
| | CT1921 | Cysteine synthase/cystathionine beta-synthase family protein; Identified by match to protein family HMM PF00291; match to protein family HMM PF00571. (456 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (338 aa) |
| | CT1955 | Magnesium-chelatase, bacteriochlorophyll c-specific subunit; Identified by similarity to GP:2661856; match to protein family HMM PF02514; match to protein family HMM TIGR02025. (1295 aa) |
| | bchH-1 | Magnesium-protoporphyrin methyltransferase; Identified by similarity to EGAD:6772; match to protein family HMM PF02514; match to protein family HMM TIGR02025. (1278 aa) |
| | bchM | Magnesium-protoporphyrin IX monomethyl ester oxidative cyclase, 25 kDa subunit; Identified by similarity to EGAD:8986; match to protein family HMM PF07109; match to protein family HMM TIGR02021. (232 aa) |
| | bchE | Magnesium-protoporphyrin IX monomethyl ester oxidative cyclase, 66 kDa subunit; Identified by similarity to EGAD:9307; match to protein family HMM PF02310; match to protein family HMM PF04055; match to protein family HMM TIGR02026. (546 aa) |
| | lpd-2 | Dihydrolipoamide dehydrogenase; Identified by similarity to EGAD:23101; match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992. (467 aa) |
| | eno-1 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (293 aa) |
| | bchK | Bacteriochlorophyll c synthase; Identified by similarity to SP:P33326; match to protein family HMM PF01040. (358 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa) |
| | CT2007 | Glucokinase, putative; Identified by match to protein family HMM PF00480. (336 aa) |
| | glgA | Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (488 aa) |
| | bchJ | Bacteriochlorophyll synthase, 23 kDa subunit; Identified by similarity to GP:3820550; match to protein family HMM TIGR02019. (191 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (257 aa) |
| | ThrA | Aspartokinase/homoserine dehydrogenase; Identified by similarity to EGAD:9487; similarity to EGAD:75016; match to protein family HMM PF00696; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447; match to protein family HMM TIGR00657. (818 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (324 aa) |
| | thrC | Threonine synthase; Identified by similarity to EGAD:7615; similarity to EGAD:16850; match to protein family HMM PF00291; match to protein family HMM TIGR00260. (441 aa) |
| | plsC | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Identified by similarity to EGAD:88611; match to protein family HMM PF01553; match to protein family HMM TIGR00530; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (232 aa) |
| | ribH | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (155 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (351 aa) |
| | CT2040 | Succinate/fumarate oxidoreductase, putative; Identified by similarity to GP:3378542; match to protein family HMM PF02754. (283 aa) |
| | CT2041 | Succinate/fumarate oxidoreductase, iron-sulfur protein, putative; Identified by match to protein family HMM PF00111; match to protein family HMM TIGR00384. (345 aa) |
| | CT2042 | Succinate/fumarate oxidoreductase, flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF02910; match to protein family HMM PF07992; match to protein family HMM TIGR01812. (567 aa) |
| | CT2056 | Mannose-1-phosphate guanylyltransferase, putative; Identified by similarity to GP:3323397; match to protein family HMM PF00483. (309 aa) |
| | hemL | Glutamate-1-semialdehyde 2,1-aminomutase; Identified by similarity to EGAD:19989; match to protein family HMM PF00202; match to protein family HMM TIGR00713; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (431 aa) |
| | leuA-2 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (562 aa) |
| | plsX | Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (338 aa) |
| | fabD | Malonyl CoA-acyl carrier protein transacylase; Identified by similarity to EGAD:22444; match to protein family HMM PF00698; match to protein family HMM TIGR00128. (305 aa) |
| | fabG | 3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (245 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (81 aa) |
| | gcvP2 | Glycine cleavage system P protein, subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (486 aa) |
| | bchZ | Chlorophyllide reductase, bchZ subunit; Identified by similarity to EGAD:8283; match to protein family HMM PF00148; match to protein family HMM PF06710; match to protein family HMM TIGR02014. (468 aa) |
| | bchL | Protochlorophyllide reductase, iron-sulfur ATP-binding protein; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP. (276 aa) |
| | bchB | Protochlorophyllide reductase, ChlB subunit; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex. (537 aa) |
| | bchN | Protochlorophyllide reductase, ChlN subunit; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex. (420 aa) |
| | CT2159 | Mannose-1-phosphate guanylyltransferase, putative; Identified by similarity to EGAD:13456; match to protein family HMM PF00483. (374 aa) |
| | CT2212 | Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583; Belongs to the acetyltransferase family. (155 aa) |
| | pgk | Phosphoglycerate kinase; Identified by similarity to EGAD:81744; match to protein family HMM PF00162; Belongs to the phosphoglycerate kinase family. (397 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (621 aa) |
| | CT2238 | Siroheme synthetase, putative; Identified by similarity to EGAD:14346; match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family. (461 aa) |
| | CT2239 | Porphyrin biosynthesis protein, putative; Similar to N-terminal 140 aa of E. coli cysG (siroheme synthase) and adjacent to hemD, which is similar to the remainder of cysG; identified by similarity to EGAD:6104; match to protein family HMM TIGR01470. (157 aa) |
| | bchP | Geranylgeranyl hydrogenase; Identified by similarity to EGAD:102228; match to protein family HMM PF01360; match to protein family HMM PF07992; match to protein family HMM TIGR02023; match to protein family HMM TIGR02032. (383 aa) |
| | sdhB | Succinate dehydrogenase, iron-sulfur protein; Identified by match to protein family HMM PF00037. (257 aa) |
| | sdhA | Succinate dehydrogenase, flavoprotein subunit; Identified by similarity to EGAD:21386; match to protein family HMM PF00890; match to protein family HMM PF02910; match to protein family HMM PF07992; match to protein family HMM TIGR01811. (646 aa) |
| | CT2268 | Succinate dehydrogenase, cytochrome subunit, putative; Identified by similarity to GP:6580638; match to protein family HMM TIGR02046. (240 aa) |
