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cdd cdd punA punA deoA deoA upp upp cmk cmk pyrF pyrF dut dut pyrC pyrC pyrE pyrE dcd dcd pyrD pyrD ndk ndk pyrC-2 pyrC-2 pyrB pyrB pyrG pyrG mazG mazG pyrH pyrH surE surE cpdB cpdB nrdJ nrdJ carB carB tmk tmk APG91313.1 APG91313.1 psuG psuG thyA thyA carA carA tdk tdk preT preT preA preA amaB amaB dht dht amaB-2 amaB-2 APG92489.1 APG92489.1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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cddCytidine deaminase Cdd; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (131 aa)
punAPurine nucleoside phosphorylase 1; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (265 aa)
deoAThymidine phosphorylase DeoA; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. (438 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa)
cmkCytidylate kinase; Region:COG0283F. (211 aa)
pyrFOrotidine 5'-phosphate decarboxylase PyrF; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (234 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (156 aa)
pyrCDihydroorotase PyrC; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (345 aa)
pyrEOrotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (232 aa)
dcd2'-deoxycytidine 5'-triphosphate deaminase protein Dcd; Region:COG0717F. (365 aa)
pyrDDihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (362 aa)
ndkNucleoside diphosphate kinase Ndk; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa)
pyrC-2Dihydroorotase PyrC; Region:COG0044F. (430 aa)
pyrBAspartate carbamoyltransferase PyrB; Region:COG0540F; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (313 aa)
pyrGCTP synthase PyrG; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa)
mazGNucleoside triphosphate pyrophosphohydrolase MazG; Region:COG3956R. (277 aa)
pyrHUridylate kinase PyrH; Catalyzes the reversible phosphorylation of UMP to UDP. (240 aa)
surEStationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (256 aa)
cpdBBifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein; Region:COG0737FV; Belongs to the 5'-nucleotidase family. (660 aa)
nrdJVitamin B12-dependent ribonucleotide reductase NrdJ; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (1261 aa)
carBCarbamoyl-phosphate synthase large subunit; Region:COG0458EF; Belongs to the CarB family. (1186 aa)
tmkThymidylate kinase Tmk; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (233 aa)
APG91313.1Sugar kinase, ribokinase family; Region:COG0524G. (315 aa)
psuGIndigoidine A related protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (312 aa)
thyAThymidylate synthase ThyA; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa)
carACarbamoyl-phosphate synthase small subunit; Region:COG0505EF; Belongs to the CarA family. (401 aa)
tdkThymidine kinase Tdk; Region:COG1435F. (195 aa)
preTNAD-dependent dihydropyrimidine dehydrogenase subunit PreT; Region:COG0493ER. (453 aa)
preANAD-dependent dihydropyrimidine dehydrogenase subunit PreA; Region:COG0167F. (437 aa)
amaBN-carbamoyl-L-amino acid hydrolase AmaB; Region:COG0624E. (416 aa)
dhtD-hydantoinase/dihydropyrimidinase Dht; Region:COG0044F. (484 aa)
amaB-2Amidase, hydantoinase/carbamoylase; Region:COG0624E. (412 aa)
APG92489.15'-nucleotidase; Region:COG0737FV; Belongs to the 5'-nucleotidase family. (621 aa)
Your Current Organism:
Sinorhizobium americanum
NCBI taxonomy Id: 194963
Other names: ATCC BAA-532, CIP 108390, DSM 15007, Ensifer americanum, Ensifer americanus, Ensifer americanus corrig. (Toledo et al. 2003) Wang et al. 2015, Ensifer sp. AC14c, Ensifer sp. CFNEI 156, S. americanum, Sinorhizobium americanum Toledo et al. 2004, Sinorhizobium americanus, Sinorhizobium sp. CFNEI 156, Sinorhizobium sp. CFNEI 54, strain CFNEI 156
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