STRINGSTRING
CPE0095 CPE0095 acdS acdS ackA ackA CPE0309 CPE0309 CPE0310 CPE0310 etfB etfB eftA eftA CPE0313 CPE0313 adh adh CPE0892 CPE0892 adhE adhE pflA pflA pflA-2 pflA-2 bdhB bdhB ackB ackB pta pta CPE1973 CPE1973 atoB atoB CPE2297 CPE2297 fixB fixB etfB-2 etfB-2 bcd bcd crt crt CPE2302 CPE2302 aldH aldH nrdG nrdG adhE-2 adhE-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CPE0095Crotonase; 258 aa, similar to gp:TTBCSOPRN_1 crotonase from Thermoanaerobacterium thermosaccharolyticum (259 aa); 58.9% identity in 253 aa overlap. (EC 4.2.1.55); 3-hydroxybutyryl-CoA dehydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
acdS378 aa, similar to sp:ACDS_CLOAB ACYL-COA DEHYDROGENASE, SHORT-CHAIN SPECIFIC (EC 1.3.99.2) (SCAD) (BUTYRYL-COA DEHYDROGENASE) from Clostridium acetobutylicum (379 aa); 58.5% identity in 378 aa overlap. 1 putative transmembrane region was found by PSORT; CPE0097. (378 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa)
CPE0309Probable transcriptional regulator; 228 aa, similar to sp:YCBG_BACSU HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN GLTP-CWLJ INTERGENIC REGION (ORF6). from Bacillus subtilis (233 aa); 30.8% identity in 224 aa overlap; GntR family. (228 aa)
CPE0310Probable lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (507 aa)
etfB262 aa, similar to sp:ETFB_CLOTS ELECTRON TRANSFER FLAVOPROTEIN BETA-SUBUNIT (BETA-ETF) (ELECTRON TRANSFER FLAVOPROTEIN SMALL SUBUNIT) (ETFSS) from Clostridium thermosaccharolyticum (260 aa); 44.9% identity in 256 aa overlap; CPE0311. (262 aa)
eftA397 aa, similar to sp:ETFA_CLOTS ELECTRON TRANSFER FLAVOPROTEIN ALPHA-SUBUNIT (ALPHA-ETF) (ELECTRON TRANSFER FLAVOPROTEIN LARGE SUBUNIT) (ETFLS) from Clostridium thermosaccharolyticum (330 aa); 49.1% identity in 212 aa overlap. 1 putative transmembrane region was found by PSORT; CPE0312. (397 aa)
CPE0313466 aa, similar to pir:D69984 glycolate oxidase subunit homolog ysfC from Bacillus subtilis (470 aa); 39.9% identity in 431 aa overlap. 2 putative transmembrane regions were found by PSORT. (466 aa)
adhAlcohol dehydrogenase; 382 aa, similar to sp:ADH2_ECOLI PROBABLE ALCOHOL DEHYDROGENASE (EC 1.1.1.1) from Escherichia coli (383 aa); 63.8% identity in 378 aa overlap; CPE0449. (382 aa)
CPE0892376 aa, similar to sp:ADH1_CLOAB NADPH-DEPENDENT BUTANOL DEHYDROGENASE (EC 1.1.1.-) (BDH) from Clostridium acetobutylicum (370 aa); 44.5% identity in 371 aa overlap. (376 aa)
adhEProbable alcohol dehydrogenase; 492 aa, similar to N-termminal of pir:DEEC acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) / alcohol dehydrogenase (EC 1.1.1.1) from Escherichia coli (891 aa); 41.1% identity in 440 aa overlap. 1 putative transmembrane region was found by PSORT; CPE0902. (492 aa)
pflA744 aa, similar to sp:PFL_CLOPA FORMATE ACETYLTRANSFERASE (EC 2.3.1.54) (PYRUVATE FORMATE-LYASE) from Clostridium pasteurianum (740 aa); 73.7% identity in 744 aa overlap. 1 putative transmembrane region was found by PSORT; CPE1153. (744 aa)
pflA-2Pyruvate formate-lyase-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (235 aa)
bdhB388 aa, similar to sp:ADH1_CLOAB NADPH-DEPENDENT BUTANOL DEHYDROGENASE (EC 1.1.1.-) (BDH) from Clostridium acetobutylicum (388 aa); 69.6% identity in 388 aa overlap; CPE1256. (388 aa)
ackBAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa)
pta335 aa, similar to sp:PTA_CLOAB PHOSPHATE ACETYLTRANSFERASE (EC 2.3.1.8) (PHOSPHOTRANSACETYLASE) from Clostridium acetobutylicum (333 aa); 62.8% identity in 317 aa overlap; CPE1725. (335 aa)
CPE1973Probable acylphosphatase; 89 aa, similar to sp:ACYP_BACSU PUTATIVE ACYLPHOSPHATASE (EC 3.6.1.7) (ACYLPHOSPHATE PHOSPHOHYDROLASE) from Bacillus subtilis (91 aa); 36.8% identity in 87 aa overlap. (89 aa)
atoB392 aa, similar to sp:THL_CLOAB ACETYL-COA ACETYLTRANSFERASE (EC 2.3.1.9) (ACETOACETYL-COA THIOLASE) from Clostridium acetobutylicum (392 aa); 77% identity in 392 aa overlap. 1 putative transmembrane region was found by PSORT; CPE2195; beta-ketothiolase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
CPE2297282 aa, similar to pir:A43723 beta-hydroxybutyryl-CoA dehydrogenase, NAD-dependent (EC 1.1.1.-) from Clostridium acetobutylicum (282 aa); 85.8% identity in 281 aa overlap. Putative N-terminal signal sequence and 1 putative transmembrane region were found by PSORT. (282 aa)
fixB3-hydroxybutyryl-CoA dehydrogenase; 335 aa, similar to sp:FIXB_CLOAB FIXB PROTEIN from Clostridium acetobutylicum (334 aa); 73.9% identity in 329 aa overlap; CPE2298. (335 aa)
etfB-2259 aa, similar to sp:ETFB_CLOAB ELECTRON TRANSFER FLAVOPROTEIN BETA-SUBUNIT (BETA-ETF) (ELECTRON TRANSFER FLAVOPROTEIN SMALL SUBUNIT) (ETFSS) from Clostridium acetobutylicum (252 aa); 71.4% identity in 245 aa overlap; CPE2299. (259 aa)
bcd379 aa, similar to sp:ACDS_CLOAB ACYL-COA DEHYDROGENASE, SHORT-CHAIN SPECIFIC (EC 1.3.99.2) (SCAD) (BUTYRYL-COA DEHYDROGENASE) from Clostridium acetobutylicum (379 aa); 72.6% identity in 379 aa overlap. 1 putative transmembrane region was found by PSORT; CPE2300. (379 aa)
crt3-hydroxybutryl-CoA dehydratase; 260 aa, similar to sp:CRT_CLOAB 3-HYDROXYBUTYRYL-COA DEHYDRATASE (EC 4.2.1.55) (CROTONASE) from Clostridium acetobutylicum (261 aa); 68.8% identity in 260 aa overlap; CPE2301; crotonase; Belongs to the enoyl-CoA hydratase/isomerase family. (260 aa)
CPE2302Conserved hypothetical protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. (212 aa)
aldH458 aa, similar to gpu:AP001510_40 aldehyde dehydrogenase from Bacillus halodurans (452 aa); 47% identity in 455 aa overlap; CPE2310. (458 aa)
nrdGProbable anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (169 aa)
adhE-2865 aa, similar to pir:A49346 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) / alcohol dehydrogenase (EC 1.1.1.1) E from Clostridium acetobutylicum (862 aa); 67.3% identity in 859 aa overlap. 1 putative transmembrane region was found by PSORT; CPE2531; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (865 aa)
Your Current Organism:
Clostridium perfringens 13
NCBI taxonomy Id: 195102
Other names: C. perfringens str. 13, Clostridium perfringens str. 13
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