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nagH nagH CPE0324 CPE0324 CPE0375 CPE0375 nanJ nanJ CPE0565 CPE0565 CPE0663 CPE0663 CPE0693 CPE0693 nanI nanI CPE0852 CPE0852 CPE0866 CPE0866 nagI nagI CPE1046 CPE1046 CPE1055 CPE1055 nagJ nagJ CPE1235 CPE1235 CPE1264 CPE1264 CPE1265 CPE1265 nagK nagK nagL nagL CPE1875 CPE1875 CPE1876 CPE1876
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
nagHHyaluronidase; Putative virulence factor which is likely to act on connective tissue during gas gangrene. (1628 aa)
CPE0324438 aa, similar to pir:T36467 probable glycosyl hydrolase from Streptomyces coelicolor (423 aa); 34% identity in 332 aa overlap. (438 aa)
CPE0375845 aa, similar to gpu:AB038772_1 endo-beta-galactosidase C from Clostridium perfringens (845 aa); 97.2% identity in 832 aa overlap. Putative N-terminal signal sequence was found by PSORT. (845 aa)
nanJExo-alpha-sialidase; 1173 aa, similar to sp:NANH_CLOSE SIALIDASE PRECURSOR (EC 3.2.1.18) (NEURAMINIDASE) from Clostridium septicum (1014 aa); 50.9% identity in 953 aa overlap. Putative N-terminal signal sequence was found by PSORT; CPE0553. (1173 aa)
CPE0565222 aa, similar to pir:MUBPA7 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) from phage T7 (151 aa); 38.7% identity in 119 aa overlap. 1 putative transmembrane region was found by PSORT; phage related. (222 aa)
CPE0663436 aa, similar to gpu:AE003864_7 hypothetical protein from Xylella fastidiosa (460 aa); 20.5% identity in 414 aa overlap. (436 aa)
CPE0693Hypothetical protein; 1686 aa, similar to pir:T29435 hypothetical protein SC3A7.16c from Streptomyces coelicolor (1361 aa); 30.7% identity in 1024 aa overlap. Putative N-terminal signal sequence was found by PSORT. (1686 aa)
nanIExo-alpha-sialidase; 694 aa, similar to pir:I40866 exo-alpha-sialidase (EC 3.2.1.18) from Clostridium perfringens (694 aa); 99.7% identity in 694 aa overlap. Putative N-terminal signal sequence was found by PSORT; CPE0725. (694 aa)
CPE0852Hypothetical protein; 473 aa, similar to gb|AAF56462.1| (AE003751) CG11909 gene product from Drosophila melanogaster (657 aa); 31% identity in 432 aa overlap; Belongs to the glycosyl hydrolase 31 family. (473 aa)
CPE08662104 aa, partially similar to sp:ANAG_HUMAN ALPHA-N-ACETYLGLUCOSAMINIDASE PRECURSOR (EC 3.2.1.50) (N-ACETYL-ALPHA- GLUCOSAMINIDASE) (NAG) from Homo sapiens (743 aa); 29.4% identity in 704 aa overlap. (2104 aa)
nagIHyaluronidase; 1297 aa, similar to sp:NAGH_CLOPE HYALURONOGLUCOSAMINIDASE PRECURSOR (EC 3.2.1.35) (HYALURONIDASE) (MU TOXIN) from Clostridium perfringens (1042 aa); 25.7% identity in 1006 aa overlap. Putative N-terminal signal sequence and 1 putative transmembrane region were found by PSORT; CPE0881; mu-toxin. (1297 aa)
CPE1046Hypothetical protein; 1965 aa, partially similar to gpu:AB012238_1 alpha-glucosidase from Bacillus thermoamyloliquefaciens (731 aa); 27.1% identity in 591 aa overlap. (1965 aa)
CPE1055Hypothetical protein; 256 aa, similar to pir:T48821 hypothetical protein 68B2.50 from Neurospora crassa (386 aa); 25% identity in 260 aa overlap. (256 aa)
nagJHyaluronidase; Binds carbohydrates. Capable of hydrolyzing the glycosidic link of O-GlcNAcylated proteins. Can bind and deglycosylate O- glycosylated peptides from mammals. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates (in vitro). Belongs to the glycosyl hydrolase 84 family. (1001 aa)
CPE1235Hypothetical protein; 317 aa, partially similar to pir:T29435 hypothetical protein SC3A7.16c from Streptomyces coelicolor (1361 aa); 23.5% identity in 226 aa overlap. (317 aa)
CPE1264Sialidase-like protein; 1588 aa, partially similar to sp:NANH_MICVI SIALIDASE PRECURSOR (EC 3.2.1.18) (NEURAMINIDASE) from Micromonospora viridifaciens (647 aa); 36.1% identity in 119 aa overlap. Putative N-terminal signal sequence was found by PSORT. (1588 aa)
CPE1265Hypothetical protein; 587 aa, no significant homology. (587 aa)
nagKHyaluronidase; 1163 aa, similar to sp:NAGH_CLOPE HYALURONOGLUCOSAMINIDASE PRECURSOR (EC 3.2.1.35) (HYALURONIDASE) (MU TOXIN) from Clostridium perfringens (1042 aa); 37.8% identity in 874 aa overlap. Putative N-terminal signal sequence and 1 putative transmembrane region were found by PSORT; CPE1279; mu-toxin. (1163 aa)
nagLHyaluronidase; 1127 aa, similar to >sp:NAGH_CLOPE HYALURONOGLUCOSAMINIDASE PRECURSOR (EC 3.2.1.35) (HYALURONIDASE) (MU TOXIN from Clostridium perfringens (1042 aa); 27.8% identity in 946 aa overlap; CPE1523; mu-toxin. (1127 aa)
CPE1875Conserved hypothetical protein; 1479 aa, partially similar to gpu:AP001510_17 BH0842 gene product from Bacillus halodurans (795 aa); 40.8% identity in 762 aa overlap. Putative N-terminal signal sequence was found by PSORT. (1479 aa)
CPE1876Conserved hypothetical protein; 750 aa, partially similar to gpu:AE003864_7 hypothetical protein from Xylella fastidiosa (460 aa); 33.6% identity in 438 aa overlap. Putative N-terminal signal sequence was found by PSORT. (750 aa)
Your Current Organism:
Clostridium perfringens 13
NCBI taxonomy Id: 195102
Other names: C. perfringens str. 13, Clostridium perfringens str. 13
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