(13 nodes) Mixed, incl. Chromosome segregation, and DNA catabolic process network (Clostridium perfringens ATCC 13124)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	smc	Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1185 aa)
	scpB	Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (195 aa)
	scpA	Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. (248 aa)
	xerD	Tyrosine recombinase XerD; Identified by similarity to SP:P46352; match to protein family HMM PF00589; match to protein family HMM PF02899; match to protein family HMM TIGR02225; Belongs to the 'phage' integrase family. (290 aa)
	spoIIM	Stage II sporulation protein M; Identified by similarity to SP:P37873; match to protein family HMM PF01944; match to protein family HMM TIGR02831. (206 aa)
	CPF_2066	Hypothetical protein; Identified by glimmer; putative. (101 aa)
	recN	DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (565 aa)
	argR-2	Arginine repressor; Regulates arginine biosynthesis genes. (150 aa)
	CPF_2072	Identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478. (271 aa)
	xseB	Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (75 aa)
	xseA	Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (400 aa)
	nusB	N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (135 aa)
	CPF_2639	Conserved domain protein; Identified by similarity to GB:AAO79146.1. (430 aa)

Your Current Organism:

Clostridium perfringens ATCC 13124

NCBI taxonomy Id: 195103
Other names: C. perfringens ATCC 13124, Clostridium perfringens str. ATCC 13124, Clostridium perfringens strain ATCC 13124

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CPF_2072	argR-2	CPF_2072	CPF_2070	Identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478.	Arginine repressor; Regulates arginine biosynthesis genes.	0.681
CPF_2072	nusB	CPF_2072	CPF_2078	Identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478.	N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.	0.714
CPF_2072	recN	CPF_2072	CPF_2069	Identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478.	DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.	0.651
CPF_2072	xseA	CPF_2072	CPF_2076	Identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478.	Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.	0.763
CPF_2072	xseB	CPF_2072	CPF_2075	Identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478.	Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.	0.791
CPF_2639	scpA	CPF_2639	CPF_2060	Conserved domain protein; Identified by similarity to GB:AAO79146.1.	Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.	0.630
argR-2	CPF_2072	CPF_2070	CPF_2072	Arginine repressor; Regulates arginine biosynthesis genes.	Identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478.	0.681
argR-2	nusB	CPF_2070	CPF_2078	Arginine repressor; Regulates arginine biosynthesis genes.	N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.	0.555
argR-2	recN	CPF_2070	CPF_2069	Arginine repressor; Regulates arginine biosynthesis genes.	DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.	0.856
argR-2	xseA	CPF_2070	CPF_2076	Arginine repressor; Regulates arginine biosynthesis genes.	Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.	0.593
argR-2	xseB	CPF_2070	CPF_2075	Arginine repressor; Regulates arginine biosynthesis genes.	Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.	0.611
nusB	CPF_2072	CPF_2078	CPF_2072	N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.	Identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478.	0.714
nusB	argR-2	CPF_2078	CPF_2070	N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.	Arginine repressor; Regulates arginine biosynthesis genes.	0.555
nusB	recN	CPF_2078	CPF_2069	N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.	DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.	0.534
nusB	xseA	CPF_2078	CPF_2076	N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.	Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.	0.780
nusB	xseB	CPF_2078	CPF_2075	N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.	Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.	0.759
recN	CPF_2072	CPF_2069	CPF_2072	DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.	Identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478.	0.651
recN	argR-2	CPF_2069	CPF_2070	DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.	Arginine repressor; Regulates arginine biosynthesis genes.	0.856
recN	nusB	CPF_2069	CPF_2078	DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.	N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.	0.534
recN	xerD	CPF_2069	CPF_2063	DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.	Tyrosine recombinase XerD; Identified by similarity to SP:P46352; match to protein family HMM PF00589; match to protein family HMM PF02899; match to protein family HMM TIGR02225; Belongs to the 'phage' integrase family.	0.418