(33 nodes) DNA replication initiation, and Activation of the pre-replicative complex network (Laodelphax striatellus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A482WI30	Uncharacterized protein. (361 aa)
	A0A482WJN0	MCM domain-containing protein. (98 aa)
	A0A482WLA1	Uncharacterized protein. (660 aa)
	A0A482WLD0	Uncharacterized protein. (190 aa)
	A0A482WLW0	Mcm10 domain-containing protein. (805 aa)
	A0A482WMW5	DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (170 aa)
	A0A482WN63	DNA helicase; Belongs to the MCM family. (878 aa)
	A0A482WRR2	Uncharacterized protein. (1304 aa)
	A0A482WTT8	RRM domain-containing protein. (701 aa)
	A0A482WUF6	Uncharacterized protein. (569 aa)
	A0A482X191	DNA helicase; Belongs to the MCM family. (889 aa)
	A0A482X2F2	Protein kinase domain-containing protein. (635 aa)
	A0A482X3E8	CDT1 domain-containing protein. (744 aa)
	A0A482X3Q7	Uncharacterized protein. (689 aa)
	A0A482X447	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (223 aa)
	A0A482X5P9	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (511 aa)
	A0A482X5T6	DNA helicase; Belongs to the MCM family. (733 aa)
	A0A482X6R7	MCM domain-containing protein; Belongs to the MCM family. (1222 aa)
	A0A482X753	DNA helicase; Belongs to the MCM family. (823 aa)
	A0A482X7H0	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (358 aa)
	A0A482XCZ3	DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (211 aa)
	A0A482XFS2	MCM domain-containing protein; Belongs to the MCM family. (645 aa)
	A0A482XFW0	Uncharacterized protein. (658 aa)
	A0A482XGK2	Sld5 domain-containing protein. (202 aa)
	A0A482XGY3	Uncharacterized protein. (99 aa)
	A0A482XHP9	DNA helicase; Belongs to the MCM family. (777 aa)
	A0A482XHX5	Uncharacterized protein. (1086 aa)
	A0A482XJ24	AAA_16 domain-containing protein. (426 aa)
	A0A482XRB6	TIMELESS_C domain-containing protein. (268 aa)
	A0A482XRH7	Uncharacterized protein. (591 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (665 aa)
	A0A482XUL9	TIMELESS domain-containing protein. (592 aa)
	A0A482XVS6	DBF4-type domain-containing protein. (487 aa)

Your Current Organism:

Laodelphax striatellus

NCBI taxonomy Id: 195883
Other names: L. striatellus, Laodelphax striatella, small brown planthopper

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A482WI30	A0A482WJN0	A0A482WI30	A0A482WJN0	Uncharacterized protein.	MCM domain-containing protein.	0.968
A0A482WI30	A0A482WLD0	A0A482WI30	A0A482WLD0	Uncharacterized protein.	Uncharacterized protein.	0.431
A0A482WI30	A0A482WLW0	A0A482WI30	A0A482WLW0	Uncharacterized protein.	Mcm10 domain-containing protein.	0.883
A0A482WI30	A0A482WMW5	A0A482WI30	A0A482WMW5	Uncharacterized protein.	DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.	0.989
A0A482WI30	A0A482WN63	A0A482WI30	A0A482WN63	Uncharacterized protein.	DNA helicase; Belongs to the MCM family.	0.991
A0A482WI30	A0A482WRR2	A0A482WI30	A0A482WRR2	Uncharacterized protein.	Uncharacterized protein.	0.559
A0A482WI30	A0A482WTT8	A0A482WI30	A0A482WTT8	Uncharacterized protein.	RRM domain-containing protein.	0.473
A0A482WI30	A0A482WUF6	A0A482WI30	A0A482WUF6	Uncharacterized protein.	Uncharacterized protein.	0.991
A0A482WI30	A0A482X191	A0A482WI30	A0A482X191	Uncharacterized protein.	DNA helicase; Belongs to the MCM family.	0.991
A0A482WI30	A0A482X2F2	A0A482WI30	A0A482X2F2	Uncharacterized protein.	Protein kinase domain-containing protein.	0.414
A0A482WI30	A0A482X3E8	A0A482WI30	A0A482X3E8	Uncharacterized protein.	CDT1 domain-containing protein.	0.573
A0A482WI30	A0A482X447	A0A482WI30	A0A482X447	Uncharacterized protein.	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.	0.998
A0A482WI30	A0A482X5P9	A0A482WI30	A0A482X5P9	Uncharacterized protein.	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	0.612
A0A482WI30	A0A482X5T6	A0A482WI30	A0A482X5T6	Uncharacterized protein.	DNA helicase; Belongs to the MCM family.	0.992
A0A482WI30	A0A482X6R7	A0A482WI30	A0A482X6R7	Uncharacterized protein.	MCM domain-containing protein; Belongs to the MCM family.	0.968
A0A482WI30	A0A482X753	A0A482WI30	A0A482X753	Uncharacterized protein.	DNA helicase; Belongs to the MCM family.	0.991
A0A482WI30	A0A482X7H0	A0A482WI30	A0A482X7H0	Uncharacterized protein.	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	0.969
A0A482WI30	A0A482XCZ3	A0A482WI30	A0A482XCZ3	Uncharacterized protein.	DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.	0.989
A0A482WI30	A0A482XFS2	A0A482WI30	A0A482XFS2	Uncharacterized protein.	MCM domain-containing protein; Belongs to the MCM family.	0.889
A0A482WI30	A0A482XFW0	A0A482WI30	A0A482XFW0	Uncharacterized protein.	Uncharacterized protein.	0.889