(60 nodes) FCERI mediated NF-kB activation network (Laodelphax striatellus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A482XII9	PCI domain-containing protein. (460 aa)
	A0A482XGT4	Proteasome subunit beta; Belongs to the peptidase T1B family. (236 aa)
	A0A482XFD2	Uncharacterized protein. (325 aa)
	A0A482XFA9	ANK_REP_REGION domain-containing protein. (460 aa)
	A0A482XDJ1	Proteasome subunit beta; Belongs to the peptidase T1B family. (248 aa)
	A0A482XDC3	RPN2_C domain-containing protein. (584 aa)
	A0A482XD32	Uncharacterized protein. (179 aa)
	A0A482XCW5	AAA domain-containing protein; Belongs to the AAA ATPase family. (404 aa)
	A0A482XAY7	AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
	A0A482XAY4	PDZ domain-containing protein. (206 aa)
	A0A482X8L2	PCI domain-containing protein. (402 aa)
	A0A482X7D7	PI31_Prot_N domain-containing protein. (282 aa)
	A0A482X738	Uncharacterized protein. (436 aa)
	A0A482X720	AAA domain-containing protein; Belongs to the AAA ATPase family. (393 aa)
	A0A482X6W2	Uncharacterized protein. (126 aa)
	A0A482X6V5	Uncharacterized protein. (1157 aa)
	A0A482X6U5	JAB_MPN domain-containing protein. (358 aa)
	A0A482X6J9	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
	A0A482X2Y3	CASPASE_P20 domain-containing protein. (129 aa)
	A0A482X231	Pr_beta_C domain-containing protein. (141 aa)
	A0A482X1N0	Uncharacterized protein. (106 aa)
	A0A482X1M4	Protein kinase domain-containing protein. (792 aa)
	A0A482X0A6	Ubiquitin-like domain-containing protein. (126 aa)
	A0A482WZM0	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (261 aa)
	A0A482WYS0	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (282 aa)
	A0A482WXE5	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (250 aa)
	A0A482WWZ6	Proteasome subunit beta. (223 aa)
	A0A482WW61	AAA domain-containing protein; Belongs to the AAA ATPase family. (415 aa)
	A0A482WV72	AAA domain-containing protein; Belongs to the AAA ATPase family. (407 aa)
	A0A482WV16	MPN domain-containing protein. (311 aa)
	A0A482WRY4	CULLIN_2 domain-containing protein; Belongs to the cullin family. (813 aa)
	A0A482WPX2	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (254 aa)
	A0A482WP71	PPM-type phosphatase domain-containing protein. (482 aa)
	A0A482WNS4	Ubiquitin-like domain-containing protein. (109 aa)
	A0A482XQ15	Uncharacterized protein. (307 aa)
	A0A482XPG1	Uncharacterized protein. (518 aa)
	A0A482XP26	VWFA domain-containing protein. (411 aa)
	A0A482XNT9	PCI domain-containing protein. (439 aa)
	A0A482XK41	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (786 aa)
	A0A482XK39	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (234 aa)
	A0A482XIJ2	Proteasome subunit beta. (202 aa)
	A0A482XHF9	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (239 aa)
	M9W042_LAOST	26S proteasome non-ATPase regulatory subunit 8. (266 aa)
	A0A482XV33	Proteasome subunit beta. (205 aa)
	A0A482WMY3	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (247 aa)
	A0A482WME7	Uncharacterized protein. (541 aa)
	A0A482WM53	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (116 aa)
	A0A482WM07	PCI domain-containing protein. (383 aa)
	A0A482WLZ6	AAA domain-containing protein; Belongs to the AAA ATPase family. (434 aa)
	A0A482WFB7	PI31_Prot_N domain-containing protein. (157 aa)
	A0A482WG81	Uncharacterized protein; Belongs to the SKP1 family. (162 aa)
	A0A482WIG0	KxDL domain-containing protein. (187 aa)
	A0A482WJX7	RHD domain-containing protein. (903 aa)
	A0A0C5AQN8	26S proteasome non-ATPase regulatory subunit 7. (313 aa)
	A0A482WL60	Uncharacterized protein. (179 aa)
	A0A0C5AST9	26S proteasome non-ATPase regulatory subunit 3. (498 aa)
	A0A482XUX6	RanBP2-type domain-containing protein. (538 aa)
	A0A482XS17	Uncharacterized protein. (97 aa)
	A0A482XRY9	Uncharacterized protein. (285 aa)
	A0A482XQF4	Proteasome subunit beta. (180 aa)

Your Current Organism:

Laodelphax striatellus

NCBI taxonomy Id: 195883
Other names: L. striatellus, Laodelphax striatella, small brown planthopper

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0C5AQN8	A0A0C5AST9	A0A0C5AQN8	A0A0C5AST9	26S proteasome non-ATPase regulatory subunit 7.	26S proteasome non-ATPase regulatory subunit 3.	0.994
A0A0C5AQN8	A0A482WG81	A0A0C5AQN8	A0A482WG81	26S proteasome non-ATPase regulatory subunit 7.	Uncharacterized protein; Belongs to the SKP1 family.	0.779
A0A0C5AQN8	A0A482WJX7	A0A0C5AQN8	A0A482WJX7	26S proteasome non-ATPase regulatory subunit 7.	RHD domain-containing protein.	0.519
A0A0C5AQN8	A0A482WLZ6	A0A0C5AQN8	A0A482WLZ6	26S proteasome non-ATPase regulatory subunit 7.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.997
A0A0C5AQN8	A0A482WM07	A0A0C5AQN8	A0A482WM07	26S proteasome non-ATPase regulatory subunit 7.	PCI domain-containing protein.	0.994
A0A0C5AQN8	A0A482WM53	A0A0C5AQN8	A0A482WM53	26S proteasome non-ATPase regulatory subunit 7.	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	0.979
A0A0C5AQN8	A0A482WMY3	A0A0C5AQN8	A0A482WMY3	26S proteasome non-ATPase regulatory subunit 7.	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	0.991
A0A0C5AQN8	A0A482WNS4	A0A0C5AQN8	A0A482WNS4	26S proteasome non-ATPase regulatory subunit 7.	Ubiquitin-like domain-containing protein.	0.952
A0A0C5AQN8	A0A482WPX2	A0A0C5AQN8	A0A482WPX2	26S proteasome non-ATPase regulatory subunit 7.	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	0.992
A0A0C5AQN8	A0A482WRY4	A0A0C5AQN8	A0A482WRY4	26S proteasome non-ATPase regulatory subunit 7.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.743
A0A0C5AQN8	A0A482WV16	A0A0C5AQN8	A0A482WV16	26S proteasome non-ATPase regulatory subunit 7.	MPN domain-containing protein.	0.997
A0A0C5AQN8	A0A482WV72	A0A0C5AQN8	A0A482WV72	26S proteasome non-ATPase regulatory subunit 7.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.996
A0A0C5AQN8	A0A482WW61	A0A0C5AQN8	A0A482WW61	26S proteasome non-ATPase regulatory subunit 7.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.993
A0A0C5AQN8	A0A482WWZ6	A0A0C5AQN8	A0A482WWZ6	26S proteasome non-ATPase regulatory subunit 7.	Proteasome subunit beta.	0.987
A0A0C5AQN8	A0A482WXE5	A0A0C5AQN8	A0A482WXE5	26S proteasome non-ATPase regulatory subunit 7.	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	0.979
A0A0C5AQN8	A0A482WYS0	A0A0C5AQN8	A0A482WYS0	26S proteasome non-ATPase regulatory subunit 7.	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	0.989
A0A0C5AQN8	A0A482WZM0	A0A0C5AQN8	A0A482WZM0	26S proteasome non-ATPase regulatory subunit 7.	Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.	0.994
A0A0C5AQN8	A0A482X0A6	A0A0C5AQN8	A0A482X0A6	26S proteasome non-ATPase regulatory subunit 7.	Ubiquitin-like domain-containing protein.	0.947
A0A0C5AQN8	A0A482X1N0	A0A0C5AQN8	A0A482X1N0	26S proteasome non-ATPase regulatory subunit 7.	Uncharacterized protein.	0.966
A0A0C5AQN8	A0A482X231	A0A0C5AQN8	A0A482X231	26S proteasome non-ATPase regulatory subunit 7.	Pr_beta_C domain-containing protein.	0.966