(22 nodes) Translesion synthesis by POLK network (Laodelphax striatellus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

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Your Input:
	A0A482XR40	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	A0A482XRX1	DNA_pol_B_exo1 domain-containing protein. (113 aa)
	A0A482WIX3	RPA_C domain-containing protein. (261 aa)
	A0A482WNS4	Ubiquitin-like domain-containing protein. (109 aa)
	A0A482WQS9	AAA domain-containing protein. (1166 aa)
	A0A482WXH1	HORMA domain-containing protein. (216 aa)
	A0A482X0A6	Ubiquitin-like domain-containing protein. (126 aa)
	A0A482X543	PCNA_N domain-containing protein. (129 aa)
	A0A482X673	DNA polymerase. (765 aa)
	A0A482X6K8	Uncharacterized protein. (2225 aa)
	A0A482X7C5	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (619 aa)
	A0A482XA33	AAA domain-containing protein. (348 aa)
	A0A482XAW4	AAA domain-containing protein. (338 aa)
	A0A482XAZ0	Rep_fac_C domain-containing protein. (252 aa)
	A0A482XD97	Replication factor C subunit 1. (986 aa)
	A0A482XEL4	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1049 aa)
	A0A482XG46	Uncharacterized protein. (467 aa)
	A0A482XGK8	AAA domain-containing protein. (355 aa)
	A0A482WIG0	KxDL domain-containing protein. (187 aa)
	A0A482XKB0	AAA domain-containing protein. (358 aa)
	A0A482XLX4	Uncharacterized protein. (1927 aa)
	A0A482XNS5	Uncharacterized protein. (113 aa)

Your Current Organism:

Laodelphax striatellus

NCBI taxonomy Id: 195883
Other names: L. striatellus, Laodelphax striatella, small brown planthopper

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A482WIG0	A0A482WNS4	KxDL domain-containing protein.	Ubiquitin-like domain-containing protein.	0.892
A0A482WIX3	A0A482WNS4	RPA_C domain-containing protein.	Ubiquitin-like domain-containing protein.	0.725
A0A482WIX3	A0A482WQS9	RPA_C domain-containing protein.	AAA domain-containing protein.	0.728
A0A482WIX3	A0A482WXH1	RPA_C domain-containing protein.	HORMA domain-containing protein.	0.715
A0A482WIX3	A0A482X0A6	RPA_C domain-containing protein.	Ubiquitin-like domain-containing protein.	0.724
A0A482WIX3	A0A482X543	RPA_C domain-containing protein.	PCNA_N domain-containing protein.	0.876
A0A482WIX3	A0A482X673	RPA_C domain-containing protein.	DNA polymerase.	0.748
A0A482WIX3	A0A482X6K8	RPA_C domain-containing protein.	Uncharacterized protein.	0.748
A0A482WIX3	A0A482X7C5	RPA_C domain-containing protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.998
A0A482WIX3	A0A482XA33	RPA_C domain-containing protein.	AAA domain-containing protein.	0.963
A0A482WIX3	A0A482XAW4	RPA_C domain-containing protein.	AAA domain-containing protein.	0.887
A0A482WIX3	A0A482XAZ0	RPA_C domain-containing protein.	Rep_fac_C domain-containing protein.	0.855
A0A482WIX3	A0A482XD97	RPA_C domain-containing protein.	Replication factor C subunit 1.	0.876
A0A482WIX3	A0A482XEL4	RPA_C domain-containing protein.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.727
A0A482WIX3	A0A482XG46	RPA_C domain-containing protein.	Uncharacterized protein.	0.969
A0A482WIX3	A0A482XGK8	RPA_C domain-containing protein.	AAA domain-containing protein.	0.938
A0A482WIX3	A0A482XKB0	RPA_C domain-containing protein.	AAA domain-containing protein.	0.855
A0A482WIX3	A0A482XNS5	RPA_C domain-containing protein.	Uncharacterized protein.	0.998
A0A482WIX3	A0A482XR40	RPA_C domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.977
A0A482WIX3	A0A482XRX1	RPA_C domain-containing protein.	DNA_pol_B_exo1 domain-containing protein.	0.748