(59 nodes) Cysteine and methionine metabolism network (Laodelphax striatellus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A482WDR8	Uncharacterized protein. (715 aa)
	A0A482WDR9	Cytosine-specific methyltransferase. (748 aa)
	A0A482WFI3	Uncharacterized protein. (352 aa)
	A0A482WFI5	PABS domain-containing protein; Belongs to the spermidine/spermine synthase family. (299 aa)
	A0A482WFQ3	Uncharacterized protein. (750 aa)
	A0A482WFX1	Uncharacterized protein. (528 aa)
	A0A482WI97	Hcy-binding domain-containing protein. (305 aa)
	A0A482WIJ3	PABS domain-containing protein. (83 aa)
	A0A482WJ89	Uncharacterized protein. (267 aa)
	A0A482WKH1	Adenosylhomocysteinase. (531 aa)
	A0A482WKQ8	Uncharacterized protein; Belongs to the LDH/MDH superfamily. (383 aa)
	A0A482WMH8	PABS domain-containing protein. (389 aa)
	A0A482WMS5	Probable methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (235 aa)
	A0A482WP30	Malate dehydrogenase. (357 aa)
	A0A482WQV9	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (341 aa)
	A0A482WQZ7	Aspartate aminotransferase. (430 aa)
	A0A482WTZ9	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (501 aa)
	A0A482WUE8	Uncharacterized protein. (136 aa)
	A0A482WVI5	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (101 aa)
	A0A482WW50	Uncharacterized protein. (337 aa)
	A0A482WW88	Uncharacterized protein. (581 aa)
	A0A482WYT5	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (187 aa)
	A0A482X136	Uncharacterized protein. (145 aa)
	A0A482X218	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (360 aa)
	A0A482X253	Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family. (190 aa)
	A0A482X2A3	Aminotran_1_2 domain-containing protein. (458 aa)
	A0A482X2B4	Aminotran_1_2 domain-containing protein. (428 aa)
	A0A482X5C8	Adenosylhomocysteinase. (433 aa)
	A0A482X625	Yae1_N domain-containing protein. (140 aa)
	A0A482X7B9	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (306 aa)
	A0A482X7X9	RmlD_sub_bind domain-containing protein. (303 aa)
	A0A482X8E1	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (532 aa)
	A0A482X8M6	Cysteine dioxygenase. (224 aa)
	A0A482X945	Uncharacterized protein. (448 aa)
	A0A482X985	Uncharacterized protein. (605 aa)
	A0A482X9L8	Uncharacterized protein. (447 aa)
	A0A482X9P7	Glutathione synthetase. (481 aa)
	A0A482XA48	Uncharacterized protein. (307 aa)
	A0A482XA78	Malate dehydrogenase. (341 aa)
	A0A482XAJ8	Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (275 aa)
	A0A482XB24	PABS domain-containing protein. (285 aa)
	A0A482XBJ7	Uncharacterized protein; Belongs to the LDH/MDH superfamily. (354 aa)
	A0A482XC05	RING-type domain-containing protein. (429 aa)
	A0A482XC90	Uncharacterized protein; Belongs to the LDH/MDH superfamily. (374 aa)
	A0A482XCX6	Aspartate aminotransferase. (408 aa)
	A0A482XD95	Uncharacterized protein. (119 aa)
	A0A482XFL5	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (388 aa)
	A0A482XI47	Uncharacterized protein. (528 aa)
	A0A482XJT0	S-adenosylmethionine decarboxylase proenzyme. (349 aa)
	A0A482XJV9	Uncharacterized protein; Belongs to the LDH/MDH superfamily. (394 aa)
	A0A482XK15	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (282 aa)
	A0A482XK60	Uncharacterized protein. (257 aa)
	A0A482XM19	Uncharacterized protein. (682 aa)
	A0A482XMM8	Aminotran_5 domain-containing protein. (363 aa)
	A0A482XQ43	PALP domain-containing protein. (359 aa)
	A0A482XRR8	Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (426 aa)
	A0A482XRX4	Uncharacterized protein; Belongs to the LDH/MDH superfamily. (332 aa)
	A0A482XST3	Uncharacterized protein. (60 aa)
	A0A482XTQ7	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (357 aa)

Your Current Organism:

Laodelphax striatellus

NCBI taxonomy Id: 195883
Other names: L. striatellus, Laodelphax striatella, small brown planthopper

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A482WDR8	A0A482WDR9	Uncharacterized protein.	Cytosine-specific methyltransferase.	0.948
A0A482WDR8	A0A482WKH1	Uncharacterized protein.	Adenosylhomocysteinase.	0.873
A0A482WDR8	A0A482WQV9	Uncharacterized protein.	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.760
A0A482WDR8	A0A482X5C8	Uncharacterized protein.	Adenosylhomocysteinase.	0.874
A0A482WDR8	A0A482X7X9	Uncharacterized protein.	RmlD_sub_bind domain-containing protein.	0.896
A0A482WDR8	A0A482XFL5	Uncharacterized protein.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.862
A0A482WDR8	A0A482XJT0	Uncharacterized protein.	S-adenosylmethionine decarboxylase proenzyme.	0.866
A0A482WDR9	A0A482WDR8	Cytosine-specific methyltransferase.	Uncharacterized protein.	0.948
A0A482WDR9	A0A482WKH1	Cytosine-specific methyltransferase.	Adenosylhomocysteinase.	0.873
A0A482WDR9	A0A482WQV9	Cytosine-specific methyltransferase.	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.760
A0A482WDR9	A0A482X5C8	Cytosine-specific methyltransferase.	Adenosylhomocysteinase.	0.874
A0A482WDR9	A0A482X7X9	Cytosine-specific methyltransferase.	RmlD_sub_bind domain-containing protein.	0.896
A0A482WDR9	A0A482XFL5	Cytosine-specific methyltransferase.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.862
A0A482WDR9	A0A482XJT0	Cytosine-specific methyltransferase.	S-adenosylmethionine decarboxylase proenzyme.	0.866
A0A482WFI3	A0A482WFX1	Uncharacterized protein.	Uncharacterized protein.	0.448
A0A482WFI3	A0A482WI97	Uncharacterized protein.	Hcy-binding domain-containing protein.	0.945
A0A482WFI3	A0A482WJ89	Uncharacterized protein.	Uncharacterized protein.	0.922
A0A482WFI3	A0A482WKH1	Uncharacterized protein.	Adenosylhomocysteinase.	0.910
A0A482WFI3	A0A482WKQ8	Uncharacterized protein.	Uncharacterized protein; Belongs to the LDH/MDH superfamily.	0.690
A0A482WFI3	A0A482WQZ7	Uncharacterized protein.	Aspartate aminotransferase.	0.897