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Noca_0537 Noca_0537 Noca_1737 Noca_1737 Noca_1843 Noca_1843 Noca_2303 Noca_2303 Noca_2876 Noca_2876 Noca_3547 Noca_3547 Noca_3553 Noca_3553 Noca_3575 Noca_3575 mdh mdh sucD sucD sucC sucC Noca_4067 Noca_4067 Noca_4085 Noca_4085 Noca_0034 Noca_0034 Noca_0040 Noca_0040 Noca_0536 Noca_0536 Noca_0733 Noca_0733 Noca_0888 Noca_0888 fumC fumC Noca_1484 Noca_1484 Noca_1485 Noca_1485
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Noca_0537PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: tfu:Tfu_2674 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit. (660 aa)
Noca_1737TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase, E1 component; catalytic domain of components of various dehydrogenase complexes; Transketolase, central region; KEGG: sco:SCO5281 putative 2-oxoglutarate dehydrogenase. (1263 aa)
Noca_1843PFAM: MmgE/PrpD family protein; KEGG: sil:SPO0205 MmgE/PrpD family protein. (449 aa)
Noca_23032-oxoglutarate dehydrogenase E2 component; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: rha:RHA1_ro01151 probable dihydrolipoyllysine-residue succinyltransferase. (597 aa)
Noca_2876Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (938 aa)
Noca_3547TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; KEGG: rha:RHA1_ro01048 succinate dehydrogenase iron-sulfur protein. (258 aa)
Noca_3553TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: tfu:Tfu_2451 putative succinate dehydrogenase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (247 aa)
Noca_3575Isocitrate dehydrogenase, NADP-dependent; KEGG: sma:SAV7214 putative isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent, monomeric type; Belongs to the monomeric-type IDH family. (737 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (328 aa)
sucDsuccinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (297 aa)
sucCsuccinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (386 aa)
Noca_4067PFAM: MmgE/PrpD family protein; KEGG: bur:Bcep18194_B1168 MmgE/PrpD family protein. (468 aa)
Noca_4085PFAM: MmgE/PrpD family protein; KEGG: rxy:Rxyl_0368 MmgE/PrpD. (476 aa)
Noca_0034PFAM: FAD dependent oxidoreductase; KEGG: fal:FRAAL3119 conserved hypothetical protein; putative cyclic nucleotide-binding domain. (408 aa)
Noca_0040PFAM: MmgE/PrpD family protein; KEGG: bur:Bcep18194_B1168 MmgE/PrpD family protein. (453 aa)
Noca_0536PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: sma:SAV4876 2-oxoglutarate ferredoxin oxidoreductase, beta subunit. (371 aa)
Noca_0733PFAM: Citrate synthase; KEGG: sma:SAV3859 putative citrate synthase; Belongs to the citrate synthase family. (368 aa)
Noca_0888KEGG: rxy:Rxyl_1676 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. (447 aa)
fumCFumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa)
Noca_1484PFAM: protein of unknown function DUF1116; KEGG: mta:Moth_2121 protein of unknown function DUF1116. (472 aa)
Noca_1485PFAM: FdrA family protein; KEGG: ecp:ECP_4036 YahF/FdrA-like protein. (471 aa)
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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