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| | purU | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (282 aa) |
| | arcA | Arginine deiminase; PFAM: amidinotransferase; KEGG: rha:RHA1_ro05654 arginine deiminase. (407 aa) |
| | tadA | tRNA-adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (143 aa) |
| | Noca_0428 | PFAM: beta-lactamase domain protein; KEGG: rha:RHA1_ro04761 hypothetical protein. (366 aa) |
| | Noca_0436 | KEGG: pca:Pcar_1759 hypothetical protein. (353 aa) |
| | folE | PFAM: GTP cyclohydrolase I; KEGG: sma:SAV4667 putative GTP cyclohydrolase I. (205 aa) |
| | Noca_0468 | KEGG: tfu:Tfu_2874 hypothetical protein. (266 aa) |
| | Noca_0483 | PFAM: histone deacetylase superfamily; KEGG: tfu:Tfu_2707 putative acetoin utilization protein. (394 aa) |
| | Noca_0591 | PFAM: cyclase family protein; KEGG: pfl:PFL_4035 hypothetical polyketide cyclase. (308 aa) |
| | folD1 | Methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (296 aa) |
| | purU-2 | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (284 aa) |
| | Noca_0666 | PFAM: Amidase; KEGG: mmc:Mmcs_1995 amidase. (466 aa) |
| | Noca_0677 | PFAM: amidohydrolase; Amidohydrolase 3; KEGG: rde:RD1_2007 hydroxydechloroatrazine ethylaminohydrolase, putative. (444 aa) |
| | Noca_0788 | PFAM: peptidase S45, penicillin amidase; KEGG: sco:SCO3184 putative penicillin acylase. (872 aa) |
| | Noca_0866 | PFAM: GTP cyclohydrolase II; KEGG: sma:SAV545 putative GTP cyclohydrolase II. (215 aa) |
| | Noca_1037 | PFAM: pentapeptide repeat protein. (885 aa) |
| | Noca_1141 | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: sco:SCO4974 deaminase. (158 aa) |
| | Noca_1143 | PFAM: Transthyretin; KEGG: nfa:nfa52430 hypothetical protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (109 aa) |
| | mshB | LmbE family protein; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. (302 aa) |
| | Noca_1165 | PFAM: cyclase family protein; KEGG: rxy:Rxyl_0352 putative cyclase. (342 aa) |
| | Noca_1200 | TIGRFAM: succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: tfu:Tfu_0495 succinyl-diaminopimelate desuccinylase. (354 aa) |
| | Noca_1228 | PFAM: Amidase; KEGG: mpa:MAP2509c putative amidase; Belongs to the amidase family. (466 aa) |
| | Noca_1301 | PFAM: isochorismatase hydrolase; KEGG: mmc:Mmcs_5114 isochorismatase hydrolase. (194 aa) |
| | Noca_1333 | PFAM: peptidase S45, penicillin amidase; KEGG: dra:DRA0255 aculeacin A acylase. (799 aa) |
| | Noca_1417 | Dihydroorotase; PFAM: amidohydrolase; D-aminoacylase domain protein; Amidohydrolase 3; KEGG: mta:Moth_1302 N-acyl-D-amino-acid deacylase. (558 aa) |
| | Noca_1495 | N-isopropylammelide isopropylaminohydrolase; PFAM: Amidohydrolase 3; KEGG: bja:bll7276 putative cytosine deaminase. (423 aa) |
| | Noca_1505 | Barbiturase; Responsible for the hydrolysis of barbituric acid (2,4,6- trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid; Belongs to the cyclic amide hydrolase (CyAH) family. (371 aa) |
| | Noca_1561 | PFAM: phosphoesterase, PA-phosphatase related; KEGG: vpa:VP2408 hypothetical protein. (349 aa) |
| | Noca_1564 | PFAM: LmbE family protein; KEGG: mpa:MAP2993 hypothetical protein. (249 aa) |
| | Noca_1626 | PFAM: amidohydrolase; Amidohydrolase 3; KEGG: fra:Francci3_0845 amidohydrolase. (443 aa) |
| | Noca_1629 | PFAM: amidohydrolase; Amidohydrolase 3; KEGG: mta:Moth_1957 amidohydrolase. (474 aa) |
| | Noca_1635 | Dihydropyrimidinase; KEGG: sus:Acid_7659 dihydropyrimidinase; TIGRFAM: dihydropyrimidinase; PFAM: amidohydrolase; Amidohydrolase 3. (467 aa) |
| | Noca_1684 | PFAM: GTP cyclohydrolase II; KEGG: sma:SAV4121 putative GTP cyclohydrolase II. (200 aa) |
| | Noca_1775 | Hypothetical protein. (352 aa) |
| | Noca_1963 | PFAM: LmbE family protein; KEGG: sco:SCO0804 hypothetical protein. (245 aa) |
| | nadE | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (681 aa) |
| | Noca_2064 | PFAM: phosphoesterase, PA-phosphatase related; KEGG: vpa:VP2408 hypothetical protein. (339 aa) |
| | Noca_2066 | PFAM: LmbE family protein; KEGG: rha:RHA1_ro02076 possible LmbE-related protein. (260 aa) |
| | pdxT | Pyridoxal phosphate synthase yaaE subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (201 aa) |
| | arcA-2 | KEGG: pau:PA14_68330 arginine deiminase; TIGRFAM: arginine deiminase; PFAM: amidinotransferase. (431 aa) |
| | pyrC | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (432 aa) |
| | def | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (181 aa) |
| | Noca_2447 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (345 aa) |
| | ribBA | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (426 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (569 aa) |
| | Noca_2584 | Peptidase C26; PFAM: glutamine amidotransferase class-I; peptidase C26; KEGG: mle:ML1573 possible amidotransferase. (237 aa) |
| | def-2 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (199 aa) |
| | Noca_2643 | PFAM: protein of unknown function DUF245 domain protein; protein of unknown function DUF275 domain protein; KEGG: sma:SAV6678 proteasome component. (502 aa) |
| | Noca_2978 | LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (231 aa) |
| | hisI | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (123 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (212 aa) |
| | Noca_3059 | PFAM: protein of unknown function DUF152; KEGG: pac:PPA0762 conserved protein. (231 aa) |
| | Noca_3208 | KEGG: mmc:Mmcs_2752 hypothetical protein. (79 aa) |
| | Noca_3223 | PFAM: Amidohydrolase 3; KEGG: rha:RHA1_ro00158 probable metal-dependant glycoprotease. (538 aa) |
| | Noca_3224 | Agmatinase; TIGRFAM: putative agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: mmc:Mmcs_1825 agmatinase, putative; Belongs to the arginase family. (333 aa) |
| | Noca_3262 | PFAM: amidohydrolase; KEGG: sma:SAV6403 hypothetical protein. (361 aa) |
| | Noca_3338 | PFAM: peptidase S45, penicillin amidase; KEGG: dra:DRA0255 aculeacin A acylase. (789 aa) |
| | folE-2 | PFAM: GTP cyclohydrolase I; KEGG: nfa:nfa31470 putative GTP cyclohydrolase I. (219 aa) |
| | Noca_3358 | PFAM: Amidase; KEGG: tfu:Tfu_2207 amidase; Belongs to the amidase family. (470 aa) |
| | Noca_3363 | Acetylornithine deacetylase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: sru:SRU_2799 acetylornithine deacetylase. (375 aa) |
| | Noca_3382 | Agmatinase; TIGRFAM: putative agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: mmc:Mmcs_5283 agmatinase, putative; Belongs to the arginase family. (321 aa) |
| | Noca_3383 | PFAM: polysaccharide deacetylase; KEGG: mmc:Mmcs_2257 polysaccharide deacetylase. (299 aa) |
| | add | KEGG: sco:SCO4901 putative adenosine deaminase; TIGRFAM: adenosine deaminase; PFAM: adenosine/AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (373 aa) |
| | Noca_3537 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (133 aa) |
| | folD2 | Methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (283 aa) |
| | purH | KEGG: sma:SAV3444 putative bifunctional purine biosynthesis protein; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme, formylation region. (525 aa) |
| | cheB | Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (366 aa) |
| | Noca_3639 | PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: sma:SAV3194 hydrolase. (262 aa) |
| | Noca_3751 | KEGG: mpa:MAP1582c hypothetical protein. (115 aa) |
| | Noca_4084 | PFAM: cyclase family protein; KEGG: rxy:Rxyl_0367 putative cyclase. (280 aa) |
| | Noca_4086 | PFAM: amidohydrolase; KEGG: ana:alr5010 D-hydantoinase. (488 aa) |
| | Noca_4100 | PFAM: amidohydrolase; Amidohydrolase 3; KEGG: mma:MM2279 N-ethylammeline chlorohydrolase. (483 aa) |
| | Noca_4106 | PFAM: amidohydrolase; KEGG: aor:AO090001000163 atrazine chlorohydrolase/guanine deaminase Pfam: A_deaminase Amidohydro_3 Amidohydro_1. (465 aa) |
| | Noca_4144 | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: mca:MCA1307 cytosine deaminase. (154 aa) |
| | Noca_4160 | PFAM: cell wall hydrolase/autolysin; KEGG: fra:Francci3_1357 cell wall hydrolase/autolysin. (259 aa) |
| | Noca_4191 | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: gbe:GbCGDNIH1_1383 blasticidin-S deaminase. (147 aa) |
| | Noca_4204 | PFAM: L-asparaginase II; KEGG: sma:SAV4025 L-asparaginase II. (324 aa) |
| | Noca_4270 | Barbiturase; Responsible for the hydrolysis of barbituric acid (2,4,6- trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid. Can also use cyanuric acid as a substrate, albeit with lower efficiency. (371 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (222 aa) |
| | hutI | Imidazolonepropionase; KEGG: sco:SCO3070 putative imidazolonepropionase; TIGRFAM: imidazolonepropionase; PFAM: amidohydrolase; Amidohydrolase 3; Belongs to the metallo-dependent hydrolases superfamily. HutI family. (391 aa) |
| | Noca_4386 | PFAM: amidohydrolase; KEGG: sco:SCO3071 atrazine chlorohydrolase. (430 aa) |
| | Noca_4387 | Amidase, hydantoinase/carbamoylase family; KEGG: sco:SCO3072 N-carbamoyl-L-amino acid amidohydrolase; TIGRFAM: amidase, hydantoinase/carbamoylase family; PFAM: peptidase M20. (394 aa) |
| | dcd | dCTP deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (191 aa) |
| | Noca_4484 | PFAM: amidohydrolase; KEGG: rxy:Rxyl_0658 N-acetylglucosamine-6-phosphate deacetylase. (318 aa) |
| | Noca_4491 | PFAM: Amidohydrolase 3; KEGG: pac:PPA0940 conserved protein, putative metal-dependent hydrolase. (508 aa) |
| | Noca_4506 | TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: bce:BC2248 acetylornithine deacetylase. (428 aa) |
