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pckG-3 pckG-3 pckG-2 pckG-2 Noca_3997 Noca_3997 hemE hemE purK purK Noca_3362 Noca_3362 trpC trpC cobD cobD Noca_2438 Noca_2438 pyrF pyrF Noca_2034 Noca_2034 lysA lysA Noca_1737 Noca_1737 Noca_1734 Noca_1734 Noca_1727 Noca_1727 pckG pckG panD panD Noca_0113 Noca_0113 Noca_1144 Noca_1144 Noca_1273 Noca_1273
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pckG-3Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. (617 aa)
pckG-2Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. (614 aa)
Noca_3997PFAM: aminotransferase, class V; Pyridoxal-dependent decarboxylase; KEGG: sth:STH1274 putative sphingosine-1-phosphate lyase. (516 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (345 aa)
purK5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (399 aa)
Noca_3362Arginine decarboxylase; PFAM: aminotransferase, class V; Orn/Lys/Arg decarboxylase, major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: sth:STH3269 arginine/lysine/ornithine decarboxylase. (473 aa)
trpCPFAM: Indole-3-glycerol phosphate synthase; KEGG: tfu:Tfu_1164 indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. (260 aa)
cobDAdenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (291 aa)
Noca_2438Phosphopantothenoylcysteine decarboxylase / Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (436 aa)
pyrFTIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: sma:SAV6869 putative orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. (273 aa)
Noca_2034Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: amino acid-binding ACT domain protein; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: rha:RHA1_ro00492 malate dehydrogenase (oxaloacetate-decarboxylating). (461 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (466 aa)
Noca_1737TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase, E1 component; catalytic domain of components of various dehydrogenase complexes; Transketolase, central region; KEGG: sco:SCO5281 putative 2-oxoglutarate dehydrogenase. (1263 aa)
Noca_1734Hypothetical protein; KEGG: fra:Francci3_2783 conserved hypothetical protein. (218 aa)
Noca_1727Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: sma:SAV2981 putative malate dehydrogenase. (396 aa)
pckGPhosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (614 aa)
panDL-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (135 aa)
Noca_0113Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: amino acid-binding ACT domain protein; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: tfu:Tfu_2390 malate dehydrogenase (oxaloacetate decarboxylating). (457 aa)
Noca_1144KEGG: rha:RHA1_ro01566 possible urate oxidase, N-terminal. (163 aa)
Noca_1273PFAM: amidohydrolase 2; KEGG: nfa:nfa25480 putative amidohydrolase. (308 aa)
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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