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acsA acsA Noca_0579 Noca_0579 Noca_0618 Noca_0618 serC serC Noca_0814 Noca_0814 Noca_0815 Noca_0815 Noca_0856 Noca_0856 Noca_0860 Noca_0860 Noca_0863 Noca_0863 Noca_0865 Noca_0865 eno eno Noca_1003 Noca_1003 Noca_1066 Noca_1066 Noca_1184 Noca_1184 Noca_1185 Noca_1185 Noca_1409 Noca_1409 Noca_1410 Noca_1410 Noca_1630 Noca_1630 glyA glyA Noca_2359 Noca_2359 Noca_2360 Noca_2360 Noca_2361 Noca_2361 Noca_2574 Noca_2574 ackA ackA Noca_2954 Noca_2954 Noca_3274 Noca_3274 Noca_3295 Noca_3295 Noca_3385 Noca_3385 mdh mdh Noca_3619 Noca_3619 Noca_3951 Noca_3951 gpmA gpmA Noca_4350 Noca_4350 Noca_4393 Noca_4393
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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textmining
co-expression
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Your Input:
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (664 aa)
Noca_0579PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; KEGG: sme:SMa0257 probable methylamine. (699 aa)
Noca_0618PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sme:SMa0257 probable methylamine. (723 aa)
serCPhosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (374 aa)
Noca_0814FO synthase subunit 1; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: nfa:nfa47520 hypothetical protein. (842 aa)
Noca_0815KEGG: mbo:Mb3007 conserved hypothetical alanine rich protein. (205 aa)
Noca_0856KEGG: afu:AF1066 N5,N10-methylenetetrahydromethanopterin reductase. (356 aa)
Noca_0860PFAM: AMP-dependent synthetase and ligase; KEGG: rxy:Rxyl_1704 AMP-dependent synthetase and ligase. (541 aa)
Noca_0863FO synthase subunit 1; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: fra:Francci3_0745 conserved hypothetical protein. (852 aa)
Noca_0865KEGG: sco:SCO5557a hypothetical protein. (210 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (425 aa)
Noca_1003PFAM: fructose-bisphosphate aldolase, class-I; KEGG: bxe:Bxe_B1334 fructose-bisphosphate aldolase. (339 aa)
Noca_1066TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; KEGG: sma:SAV3215 putative glycerol-inducible protein. (339 aa)
Noca_1184PFAM: PEP-utilising enzyme, mobile region; KEGG: bsu:BG14114 similar to pyruvate,water dikinase. (592 aa)
Noca_1185Pyruvate, water dikinase; PFAM: pyruvate phosphate dikinase, PEP/pyruvate-binding; KEGG: mka:MK0252 phosphoenolpyruvate synthase/pyruvate phosphate dikinase. (275 aa)
Noca_1409TIGRFAM: F420-dependent oxidoreductase, putative; PFAM: protein of unknown function DUF129; KEGG: tfu:Tfu_2518 hypothetical protein. (321 aa)
Noca_1410LPPG:FO 2-phospho-L-lactate transferase; TIGRFAM: LPPG; PFAM: protein of unknown function UPF0052 and CofD; KEGG: sco:SCO3036 LPPG:FO 2-phopspho-L-lactate transferase. (337 aa)
Noca_1630Methylenetetrahydromethanopterin reductase; PFAM: luciferase family protein; KEGG: hma:pNG7255 F420-dependent N5,N10-methylene-tetrahydromethanopterin reductase. (333 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (482 aa)
Noca_2359Pyruvate ferredoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: rfr:Rfer_2185 thiamine pyrophosphate enzyme-like TPP-binding. (334 aa)
Noca_2360Pyruvate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rfr:Rfer_2186 pyruvate flavodoxin/ferredoxin oxidoreductase-like. (401 aa)
Noca_2361TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: rfr:Rfer_2187 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate. (190 aa)
Noca_2574KEGG: sco:SCO1808 putative phosphoserine phosphatase; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: amino acid-binding ACT domain protein; Haloacid dehalogenase domain protein hydrolase; Haloacid dehalogenase domain protein hydrolase, type 3. (420 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (402 aa)
Noca_2954Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (696 aa)
Noca_3274Alanine-glyoxylate aminotransferase apoenzyme; PFAM: aminotransferase, class V; KEGG: hma:rrnAC1999 aminotransferase class V. (389 aa)
Noca_3295KEGG: sco:SCO5557a hypothetical protein. (211 aa)
Noca_3385KEGG: sco:SCO5515 probable D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: amino acid-binding ACT domain protein; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (536 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (328 aa)
Noca_3619FO synthase subunit 2 / FO synthase subunit 1; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: rha:RHA1_ro05944 hypothetical protein. (841 aa)
Noca_3951D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (397 aa)
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (247 aa)
Noca_4350Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (343 aa)
Noca_4393PFAM: HpcH/HpaI aldolase; KEGG: fra:Francci3_2805 HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family. (363 aa)
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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