STRINGSTRING
crgA crgA BAC16843.1 BAC16843.1 gene:10740423 gene:10740423 BAC16845.1 BAC16845.1 gene:10740425 gene:10740425 BAC16847.1 BAC16847.1 gene:10740427 gene:10740427 BAC16849.1 BAC16849.1 murB murB alr alr ddl ddl odhI odhI ftsK ftsK wag31 wag31 sepF sepF gene:10742476 gene:10742476 BAC18859.1 BAC18859.1 ftsZ ftsZ ftsQ ftsQ murC murC murG murG ftsW ftsW murD murD mraY mraY murF murF murE murE ftsI ftsI gene:10742488 gene:10742488 rsmH rsmH mraZ mraZ gene:10742498 gene:10742498 murA murA BAC19741.1 BAC19741.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
crgAConserved hypothetical protein; Involved in cell division; Belongs to the CrgA family. (66 aa)
BAC16843.1Putative serine/threonine-protein kinase; CE0033, similar to AL079308-18|CAB45215.1| percent identity: 37 in 644 aa; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (660 aa)
gene:10740423Serine/threonine-protein kinases drp72; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (520 aa)
BAC16845.1Conserved hypothetical protein; CE0035, similar to AL079356-13|CAB45623.1| percent identity: 35 in 473 aa. (475 aa)
gene:10740425Putative cell division protein FtsW; Belongs to the SEDS family. (452 aa)
BAC16847.1Conserved hypothetical protein; CE0037, similar to AE006916-7|AAK44243.1| percent identity: 45 in 429 aa. (438 aa)
gene:10740427FHA domain-containing protein. (155 aa)
BAC16849.1Conserved hypothetical protein; CE0039, similar to AL079308-13|CAB45210.1| percent identity: 24 in 284 aa. (298 aa)
murBPutative UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (563 aa)
alrAlanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (367 aa)
ddlPutative D-alanine--D-alanine ligase; Cell wall formation. (361 aa)
odhIOxoglutarate dehydrogenase inhibitor; An essential component of the PknG signaling pathway. When unphosphorylated, it inhibits the activity of 2-oxoglutarate dehydrogenase. When phosphorylated it does not inhibit 2-oxoglutarate dehydrogenase (By similarity). (142 aa)
ftsKPutative cell division protein FtsK; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity). Belongs to the FtsK/SpoIIIE/SftA family. (984 aa)
wag31Immunogenic protein antigen 84; CE2045, similar to AJ242594-1|CAB69044.2| percent identity: 74 in 351 aa. (353 aa)
sepFConserved hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (155 aa)
gene:10742476Pyridoxal phosphate homeostasis protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (234 aa)
BAC18859.1Conserved hypothetical protein; CE2049, similar to AB003132-4|BAA21688.1| percent identity: 83 in 244 aa; Belongs to the multicopper oxidase YfiH/RL5 family. (248 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (430 aa)
ftsQCell division protein FtsQ; Essential cell division protein. (222 aa)
murCUDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (489 aa)
murGPeptidoglycan biosynthesis protein MurG; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (360 aa)
ftsWCell division protein FtsW; CE2054, similar to Z95388-24|CAB08673.1| percent identity: 37 in 515 aa; Belongs to the SEDS family. (560 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (475 aa)
mraYPutative phospho-N-acetylmuramoyl-pentapeptidetransferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (366 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (528 aa)
murEUDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (526 aa)
ftsIPenicillin-binding protein; CE2059, similar to AB041009-1|BAB15945.1| percent identity: 77 in 714 aa. (715 aa)
gene:10742488Uncharacterized protein. (265 aa)
rsmHConserved hypothetical protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (338 aa)
mraZTranscriptional regulator MraZ; Belongs to the MraZ family. (158 aa)
gene:10742498Putative eukaryotic-type serine/threonine protein kinase. (741 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (421 aa)
BAC19741.1Putative membrane protein; CE2931, similar to AX064311-1|CAC25396.1| percent identity: 72 in 1005 aa. (1259 aa)
Your Current Organism:
Corynebacterium efficiens
NCBI taxonomy Id: 196164
Other names: C. efficiens YS-314, Corynebacterium efficiens DSM 44549, Corynebacterium efficiens JCM 11189, Corynebacterium efficiens YS-314, Corynebacterium efficiens str. YS-314, Corynebacterium efficiens strain YS-314
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.