STRINGSTRING
gene:10742103 gene:10742103 BAC18491.1 BAC18491.1 gene:10742080 gene:10742080 bacA bacA BAC18396.1 BAC18396.1 argR argR rplT rplT BAC18312.1 BAC18312.1 BAC18298.1 BAC18298.1 BAC18261.1 BAC18261.1 BAC17122.1 BAC17122.1 topA topA gene:10740702 gene:10740702 gene:10740670 gene:10740670 gene:10740613 gene:10740613 BAC17025.1 BAC17025.1 BAC17023.1 BAC17023.1 gene:10740608 gene:10740608 gene:10740595 gene:10740595 BAC16985.1 BAC16985.1 gene:10740554 gene:10740554 BAC16973.1 BAC16973.1 gene:10740552 gene:10740552 BAC16971.1 BAC16971.1 gyrA gyrA gyrB gyrB gene:10742107 gene:10742107 gene:10741852 gene:10741852 ddl ddl BAC18140.1 BAC18140.1 BAC18117.1 BAC18117.1 prfA prfA gene:10741703 gene:10741703 gene:10741671 gene:10741671 gene:10741669 gene:10741669 deaD deaD gene:10741629 gene:10741629 gene:10741589 gene:10741589 BAC17966.1 BAC17966.1 BAC17924.1 BAC17924.1 murD murD murG murG murC murC ftsZ ftsZ BAC19711.1 BAC19711.1 BAC19705.1 BAC19705.1 gene:10743344 gene:10743344 gene:10743266 gene:10743266 gene:10743220 gene:10743220 gene:10743211 gene:10743211 BAC19556.1 BAC19556.1 BAC19529.1 BAC19529.1 gene:10743162 gene:10743162 BAC19523.1 BAC19523.1 gene:10743160 gene:10743160 BAC19521.1 BAC19521.1 gene:10743146 gene:10743146 gene:10743121 gene:10743121 murA murA murI murI rsfS rsfS gene:10742630 gene:10742630 gene:10742517 gene:10742517 murE murE murF murF BAC18495.1 BAC18495.1 mraY mraY BAC17847.1 BAC17847.1 mfd mfd gene:10741434 gene:10741434 glmU glmU ureE ureE prfC prfC BAC17796.1 BAC17796.1 BAC17740.1 BAC17740.1 BAC17701.1 BAC17701.1 BAC17690.1 BAC17690.1 prfB prfB gene:10741196 gene:10741196 BAC17601.1 BAC17601.1 gene:10741192 gene:10741192 gene:10741188 gene:10741188 BAC17595.1 BAC17595.1 BAC17564.1 BAC17564.1 gene:10741101 gene:10741101 gene:10741072 gene:10741072 BAC17275.1 BAC17275.1 gene:10740862 gene:10740862 BAC17273.1 BAC17273.1 murB murB BAC17171.1 BAC17171.1 BAC17124.1 BAC17124.1 sepF sepF gene:10742459 gene:10742459 smc smc gene:10742347 gene:10742347 frr frr BAC18650.1 BAC18650.1 BAC18600.1 BAC18600.1 gene:10742201 gene:10742201 rubA rubA rubB rubB BAC18564.1 BAC18564.1 mltG mltG priA priA gene:10742109 gene:10742109
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gene:10742103NifU_N domain-containing protein. (148 aa)
BAC18491.1Conserved hypothetical protein; CE1681, similar to AE007020-14|AAK45777.1| percent identity: 66 in 115 aa. (136 aa)
gene:10742080NLPC_P60 domain-containing protein. (691 aa)
bacAPutative membrane protein BacA; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (327 aa)
BAC18396.1Putative ATP-dependent RNA helicase; CE1586, similar to AL646059-158|CAD14067.1| percent identity: 37 in 457 aa. (460 aa)
argRArginine repressor; Regulates arginine biosynthesis genes. (190 aa)
rplT50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (128 aa)
BAC18312.1Conserved hypothetical protein; CE1502, similar to AL138978-15|CAB72415.1| percent identity: 43 in 748 aa. (781 aa)
BAC18298.1Putative PS1 protein; CE1488, similar to AB055224-1|BAB62413.1| percent identity: 31 in 287 aa. (390 aa)
BAC18261.1Conserved hypothetical protein; CE1451, similar to AE001701-10|AAD35257.1| percent identity: 26 in 286 aa. (350 aa)
BAC17122.1Putative cytochrome c-type biogenesis protein; CE0312, similar to AL596162-29|CAC44608.1| percent identity: 39 in 263 aa. (293 aa)
topADNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (999 aa)
gene:10740702Uncharacterized protein. (898 aa)
gene:10740670Uncharacterized protein. (784 aa)
gene:10740613Uncharacterized protein. (1421 aa)
BAC17025.1Hypothetical protein; CE0215. (1207 aa)
BAC17023.1Conserved hypothetical protein; CE0213, similar to AL023596-16|CAA19164.1| percent identity: 56 in 408 aa. (423 aa)
gene:10740608Putative cobyric acid synthase. (250 aa)
gene:10740595Putative membrane protein. (899 aa)
BAC16985.1Putative glycosyl transferase; CE0175, similar to Z80343-15|CAB02461.1| percent identity: 60 in 297 aa. (310 aa)
gene:10740554Putative oxidoreductase. (488 aa)
BAC16973.1Putative oxidoreductase; CE0163, similar to AX064581-1|CAC25530.1| percent identity: 88 in 253 aa. (253 aa)
gene:10740552Putative membrane protein. (703 aa)
BAC16971.1Putative arabinosyltransferase; CE0161, similar to AX065349-1|CAC25914.1| percent identity: 76 in 1148 aa. (1157 aa)
gyrAPutative DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (863 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (687 aa)
gene:10742107Uncharacterized protein. (481 aa)
gene:10741852Putative ATP-dependent DNA helicase recG. (707 aa)
ddlPutative D-alanine--D-alanine ligase; Cell wall formation. (361 aa)
BAC18140.1Putative cysteine desulfurase; CE1330, similar to AL583923-39|CAC30661.1| percent identity: 48 in 369 aa. (373 aa)
BAC18117.1Conserved hypothetical protein; CE1307, similar to AL583920-196|CAC31518.1| percent identity: 54 in 371 aa. (388 aa)
prfAPeptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (358 aa)
gene:10741703Putative respiratory nitrate reductase delta chain. (246 aa)
gene:10741671Putative chromodomain helicase. (1034 aa)
gene:10741669HNHc domain-containing protein. (183 aa)
deaDATP-dependent RNA helicase DeaD; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (736 aa)
gene:10741629Uncharacterized protein. (456 aa)
gene:10741589Iron-sulfur cluster carrier protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (375 aa)
BAC17966.1Putative GTP-binding protein; CE1156, similar to AL596043-7|CAC44318.1| percent identity: 60 in 632 aa. (640 aa)
BAC17924.1Putative cysteine desulfurase NifS; CE1114, similar to AE000705-9|AAC06912.1| percent identity: 42 in 360 aa. (362 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (475 aa)
murGPeptidoglycan biosynthesis protein MurG; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (360 aa)
murCUDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (489 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (430 aa)
BAC19711.1Putative ATP-dependent helicase; CE2901, similar to AE005149-5|AAG20812.1| percent identity: 22 in 861 aa. (941 aa)
BAC19705.1Conserved hypothetical protein; CE2895, similar to AE005661-3|AAG59487.1| percent identity: 27 in 2062 aa. (2100 aa)
gene:10743344DNA helicase. (777 aa)
gene:10743266Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (527 aa)
gene:10743220RNase_H_2 domain-containing protein. (506 aa)
gene:10743211Uncharacterized protein. (183 aa)
BAC19556.1Conserved hypothetical protein; CE2746, similar to AL596138-2|CAC44512.1| percent identity: 32 in 382 aa. (417 aa)
BAC19529.1Putative UDP-galactopyranose mutase; CE2719, similar to AX065129-1|CAC25804.1| percent identity: 85 in 401 aa. (460 aa)
gene:10743162Glft2_N domain-containing protein. (698 aa)
BAC19523.1Conserved hypothetical protein; CE2713, similar to AL360055-27|CAB96032.1| percent identity: 32 in 172 aa. (307 aa)
gene:10743160Putative membrane protein; Belongs to the UbiA prenyltransferase family. (341 aa)
BAC19521.1Conserved hypothetical protein; CE2711, similar to AE007185-3|AAK48278.1| percent identity: 41 in 576 aa. (676 aa)
gene:10743146Putative membrane protein. (774 aa)
gene:10743121Putative membrane protein. (1003 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (421 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (316 aa)
rsfSRibosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (157 aa)
gene:10742630CHY-type domain-containing protein. (105 aa)
gene:10742517Fe-S_biosyn domain-containing protein; Belongs to the HesB/IscA family. (154 aa)
murEUDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (526 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (528 aa)
BAC18495.1Conserved hypothetical protein; CE1685, similar to Z99125-22|CAB16170.1| percent identity: 54 in 391 aa. (394 aa)
mraYPutative phospho-N-acetylmuramoyl-pentapeptidetransferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (366 aa)
BAC17847.1Conserved hypothetical protein; CE1037, similar to AL442120-9|CAC09541.1| percent identity: 32 in 202 aa. (203 aa)
mfdTranscription-repair-coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1218 aa)
gene:10741434SWIM-type domain-containing protein. (612 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (501 aa)
ureEUrease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. (149 aa)
prfCPutative peptide chain release factor; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (546 aa)
BAC17796.1Conserved hypothetical protein; CE0986, similar to AB001488-124|BAA19377.1| percent identity: 34 in 794 aa. (797 aa)
BAC17740.1Putative ATP-dependent DNA helicase; CE0930, similar to Y15254-6|CAA75552.1| percent identity: 43 in 785 aa. (825 aa)
BAC17701.1Putative DNA helicase; CE0891, similar to AL583924-93|CAC31112.1| percent identity: 75 in 547 aa. (557 aa)
BAC17690.1Conserved hypothetical protein; CE0880, similar to AL023635-5|CAA19188.1| percent identity: 39 in 200 aa. (203 aa)
prfBPeptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (389 aa)
gene:10741196DNA helicase. (694 aa)
BAC17601.1Putative ATP-dependent DNA helicase; CE0791, similar to AL021646-46|CAA16666.1| percent identity: 43 in 1075 aa; Belongs to the helicase family. UvrD subfamily. (1175 aa)
gene:10741192Putative helicase; Belongs to the helicase family. UvrD subfamily. (1024 aa)
gene:10741188Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (369 aa)
BAC17595.1Conserved hypothetical protein; CE0785, similar to Z95120-10|CAB08304.1| percent identity: 28 in 397 aa. (401 aa)
BAC17564.1Conserved hypothetical protein; CE0754, similar to U15187-21|AAA63142.1| percent identity: 35 in 508 aa. (524 aa)
gene:10741101Putative penicillin-binding protein; Belongs to the peptidase S11 family. (447 aa)
gene:10741072Putative phenylacetic acid degradation protein. (180 aa)
BAC17275.1Putative cytochrome c biogenesis protein; CE0465, similar to U00018-1|AAA17249.1| percent identity: 43 in 354 aa. (357 aa)
gene:10740862ResB domain-containing protein. (544 aa)
BAC17273.1Putative cytochrome C-type biogenesis protein CcsA; CE0463, similar to U00018-4|AAA17226.1| percent identity: 53 in 248 aa. (283 aa)
murBPutative UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (563 aa)
BAC17171.1Putative undecaprenyl phosphate alpha-n-acetylglucosaminyltransferase; CE0361, similar to AF236052-10|AAF72959.1| percent identity: 27 in 325 aa. (336 aa)
BAC17124.1Hypothetical protein; CE0314. (181 aa)
sepFConserved hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (155 aa)
gene:10742459Uncharacterized protein. (205 aa)
smcPutative chromosome segregation SMC protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1169 aa)
gene:10742347Putative magnesium chelatase. (507 aa)
frrPutative ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (185 aa)
BAC18650.1Conserved hypothetical protein; CE1840, similar to Z98209-10|CAB10907.1| percent identity: 51 in 447 aa. (454 aa)
BAC18600.1Conserved hypothetical protein; CE1790, similar to AL583922-58|CAC30455.1| percent identity: 22 in 390 aa. (470 aa)
gene:10742201Uncharacterized protein. (155 aa)
rubAHolliday junction DNA-helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (204 aa)
rubBHolliday junction DNA-helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (360 aa)
BAC18564.1Conserved hypothetical protein; CE1754, similar to AB056583-2|BAB64333.1| percent identity: 34 in 708 aa. (886 aa)
mltGConserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (396 aa)
priAConserved hypothetical protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (685 aa)
gene:10742109Uncharacterized protein. (590 aa)
Your Current Organism:
Corynebacterium efficiens
NCBI taxonomy Id: 196164
Other names: C. efficiens YS-314, Corynebacterium efficiens DSM 44549, Corynebacterium efficiens JCM 11189, Corynebacterium efficiens YS-314, Corynebacterium efficiens str. YS-314, Corynebacterium efficiens strain YS-314
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