STRINGSTRING
gene:10740509 gene:10740509 gene:10740534 gene:10740534 nth nth gene:10741091 gene:10741091 BAC17732.1 BAC17732.1 ligA ligA ung ung polA polA mutM mutM BAC19338.1 BAC19338.1 gene:10743026 gene:10743026 gene:10743104 gene:10743104 gene:10743284 gene:10743284
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gene:10740509Putative 3-methyladenine DNA glycosylase; Belongs to the DNA glycosylase MPG family. (240 aa)
gene:10740534Putative DNA-3-methyladenine glycosidase. (211 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (264 aa)
gene:10741091Putative exodeoxyribonuclease. (331 aa)
BAC17732.1Putative endonuclease; CE0922, similar to D90913-122|BAA18384.1| percent identity: 30 in 257 aa; Belongs to the FPG family. (260 aa)
ligAPutative DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity). (938 aa)
ungUracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (238 aa)
polAPutative DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (945 aa)
mutMFormamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (285 aa)
BAC19338.1Conserved hypothetical protein; CE2528, similar to AF121797-1|AAD21076.1| percent identity: 46 in 293 aa. (326 aa)
gene:10743026Putative exodeoxyribonuclease III. (261 aa)
gene:10743104Putative 3-methyladenine-DNA glycosylase. (196 aa)
gene:10743284Putative DNA-formamidopyrimidine glycosylase; Belongs to the FPG family. (307 aa)
Your Current Organism:
Corynebacterium efficiens
NCBI taxonomy Id: 196164
Other names: C. efficiens YS-314, Corynebacterium efficiens DSM 44549, Corynebacterium efficiens JCM 11189, Corynebacterium efficiens YS-314, Corynebacterium efficiens str. YS-314, Corynebacterium efficiens strain YS-314
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.