(11 nodes) Mixed, incl. This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group., and Thioester reductase-like domain network (Streptomyces olivochromogenes)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

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protein homology

Your Input:
	KUN44701.1	Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (4705 aa)
	KUN44702.1	Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (864 aa)
	KUN44083.1	Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family. (854 aa)
	KUN43411.1	Erythronolide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (2386 aa)
	KUN43599.1	Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the P-Pant transferase superfamily. (1501 aa)
	KUN39667.1	DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (2669 aa)
	pksL	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
	KUN37596.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (724 aa)
	dhbB	Phosphopantetheine attachment domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (85 aa)
	dhbF	Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1493 aa)
	ppsD	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (2225 aa)

Your Current Organism:

Streptomyces olivochromogenes

NCBI taxonomy Id: 1963
Other names: ATCC 25479, ATCC 3336, Actinomyces olivochromogenus, CBS 889.69, DSM 40451, IFO 13067, IFO 3178, IMET 40352, ISP 5451, JCM 4163, JCM 4500, KCTC 9064, NBRC 13067, NBRC 3178, NRRL-ISP 5451, S. olivochromogenes, Streptomyces olivichromogenes, Streptomyces olivochromogenus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KUN37596.1	KUN39667.1	AQJ27_45935	AQJ27_41875	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.991
KUN37596.1	KUN43411.1	AQJ27_45935	AQJ27_30500	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Erythronolide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
KUN37596.1	KUN43599.1	AQJ27_45935	AQJ27_30505	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the P-Pant transferase superfamily.	0.987
KUN37596.1	KUN44083.1	AQJ27_45935	AQJ27_28730	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family.	0.979
KUN37596.1	KUN44701.1	AQJ27_45935	AQJ27_25135	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
KUN37596.1	KUN44702.1	AQJ27_45935	AQJ27_25140	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.959
KUN37596.1	dhbB	AQJ27_45935	AQJ27_48595	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphopantetheine attachment domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
KUN37596.1	dhbF	AQJ27_45935	AQJ27_48600	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.980
KUN37596.1	pksL	AQJ27_45935	AQJ27_45900	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.958
KUN37596.1	ppsD	AQJ27_45935	AQJ27_50650	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
KUN39667.1	KUN37596.1	AQJ27_41875	AQJ27_45935	DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.991
KUN39667.1	KUN43411.1	AQJ27_41875	AQJ27_30500	DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Erythronolide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.994
KUN39667.1	KUN43599.1	AQJ27_41875	AQJ27_30505	DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the P-Pant transferase superfamily.	0.975
KUN39667.1	KUN44083.1	AQJ27_41875	AQJ27_28730	DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family.	0.950
KUN39667.1	KUN44701.1	AQJ27_41875	AQJ27_25135	DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
KUN39667.1	KUN44702.1	AQJ27_41875	AQJ27_25140	DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.987
KUN39667.1	dhbB	AQJ27_41875	AQJ27_48595	DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphopantetheine attachment domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.968
KUN39667.1	dhbF	AQJ27_41875	AQJ27_48600	DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.981
KUN39667.1	pksL	AQJ27_41875	AQJ27_45900	DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.981
KUN39667.1	ppsD	AQJ27_41875	AQJ27_50650	DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998

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