STRINGSTRING
glpK glpK KUN48549.1 KUN48549.1 KUN47372.1 KUN47372.1 arc arc KUN47374.1 KUN47374.1 pup pup prcB prcB prcA prcA KUN47660.1 KUN47660.1 KUN46268.1 KUN46268.1 KUN45204.1 KUN45204.1 KUN42932.1 KUN42932.1 KUN41405.1 KUN41405.1 KUN35322.1 KUN35322.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (507 aa)
KUN48549.1Signal protein PDZ; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
KUN47372.1Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (101 aa)
arcProteasome ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. (588 aa)
KUN47374.1Pup deamidase/depupylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa)
pupUbiquitin; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation. (72 aa)
prcBProteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. (281 aa)
prcAProteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. (248 aa)
KUN47660.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (130 aa)
KUN46268.1Protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (626 aa)
KUN45204.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
KUN42932.1Protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (494 aa)
KUN41405.1Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
KUN35322.1Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)
Your Current Organism:
Streptomyces olivochromogenes
NCBI taxonomy Id: 1963
Other names: ATCC 25479, ATCC 3336, Actinomyces olivochromogenus, CBS 889.69, DSM 40451, IFO 13067, IFO 3178, IMET 40352, ISP 5451, JCM 4163, JCM 4500, KCTC 9064, NBRC 13067, NBRC 3178, NRRL-ISP 5451, S. olivochromogenes, Streptomyces olivichromogenes, Streptomyces olivochromogenus
Server load: low (36%) [HD]