node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cgl2136 | cysE | cg2344 | cg2834 | Hyp. Cystathionine beta-Synthase. | Serine O-Acetyltransferase. | 0.814 |
cysE | Cgl2136 | cg2834 | cg2344 | Serine O-Acetyltransferase. | Hyp. Cystathionine beta-Synthase. | 0.814 |
cysE | cysK | cg2834 | cg2833 | Serine O-Acetyltransferase. | O-Acetylserine (Thiol)-Lyase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.999 |
cysE | glyA | cg2834 | cg1133 | Serine O-Acetyltransferase. | Serine Hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.894 |
cysE | serA | cg2834 | cg1451 | Serine O-Acetyltransferase. | Phosphoglycerate Dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.691 |
cysE | serB | cg2834 | cg2779 | Serine O-Acetyltransferase. | Phosphoserine Phosphatase. | 0.869 |
cysK | cysE | cg2833 | cg2834 | O-Acetylserine (Thiol)-Lyase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Serine O-Acetyltransferase. | 0.999 |
cysK | glyA | cg2833 | cg1133 | O-Acetylserine (Thiol)-Lyase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Serine Hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.515 |
cysK | serC | cg2833 | cg0948 | O-Acetylserine (Thiol)-Lyase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Phosphoserine Transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.925 |
glyA | cysE | cg1133 | cg2834 | Serine Hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Serine O-Acetyltransferase. | 0.894 |
glyA | cysK | cg1133 | cg2833 | Serine Hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | O-Acetylserine (Thiol)-Lyase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.515 |
glyA | serA | cg1133 | cg1451 | Serine Hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoglycerate Dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.728 |
glyA | serB | cg1133 | cg2779 | Serine Hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoserine Phosphatase. | 0.986 |
glyA | serC | cg1133 | cg0948 | Serine Hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoserine Transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.878 |
serA | cysE | cg1451 | cg2834 | Phosphoglycerate Dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Serine O-Acetyltransferase. | 0.691 |
serA | glyA | cg1451 | cg1133 | Phosphoglycerate Dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Serine Hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.728 |
serA | serB | cg1451 | cg2779 | Phosphoglycerate Dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Phosphoserine Phosphatase. | 0.741 |
serA | serC | cg1451 | cg0948 | Phosphoglycerate Dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Phosphoserine Transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.988 |
serB | cysE | cg2779 | cg2834 | Phosphoserine Phosphatase. | Serine O-Acetyltransferase. | 0.869 |
serB | glyA | cg2779 | cg1133 | Phosphoserine Phosphatase. | Serine Hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.986 |