STRINGSTRING
rpmH rpmH prpB2 prpB2 Cgl0679 Cgl0679 pmmB pmmB amiA amiA prpB1 prpB1 Cgl0731 Cgl0731 Cgl0733 Cgl0733 Cgl0737 Cgl0737 Cgl0739 Cgl0739 hpf hpf Cgl0765 Cgl0765 rhlE rhlE Cgl0778 Cgl0778 pdxS pdxS Cgl0809 Cgl0809 Cgl0822 Cgl0822 serC serC Cgl0856 Cgl0856 rpsR rpsR rpsN rpsN rpmG rpmG rpmB rpmB rpmE rpmE rpmF rpmF pmt pmt Cgl0894 Cgl0894 Cgl0896 Cgl0896 ispE ispE Cgl0919 Cgl0919 Cgl0928 Cgl0928 rplY rplY pabAB pabAB Cgl1014 Cgl1014 ssiF ssiF ssiG ssiG ychF ychF Cgl1036 Cgl1036 Cgl1057 Cgl1057 Cgl1059 Cgl1059 Cgl1060 Cgl1060 Cgl1067 Cgl1067 Cgl1072 Cgl1072 Cgl1081 Cgl1081 cg1241 cg1241 Cgl1105 Cgl1105 mgtE1 mgtE1 Cgl1126 Cgl1126 metE metE deaD deaD Cgl1164 Cgl1164 Cgl1166 Cgl1166 lysA lysA fadD4 fadD4 fixB fixB nifS1 nifS1 Cgl1236 Cgl1236 Cgl1260 Cgl1260 Cgl1264 Cgl1264 Cgl1278 Cgl1278 Cgl1279 Cgl1279 Cgl1281 Cgl1281 Cgl1290 Cgl1290 entC entC rpsA rpsA ptsG ptsG rpmI rpmI rplT rplT argC argC argB argB Cgl1409 Cgl1409 recN recN parA2 parA2 Cgl1450 Cgl1450 Cgl1489 Cgl1489 mcmB mcmB mcmA mcmA hemH hemH Cgl1547 Cgl1547 nifS2 nifS2 sufC sufC sufD sufD sufB sufB ctaA ctaA ocd ocd gap gap priA priA ihf ihf Cgl1631 Cgl1631 Cgl1633 Cgl1633 Cgl1634 Cgl1634 Cgl1637 Cgl1637 tesB2 tesB2 priP priP Cgl1743 Cgl1743 Cgl1758 Cgl1758 Cgl1760 Cgl1760 Cgl1783 Cgl1783 Cgl1790 Cgl1790 Cgl1843 Cgl1843 dtd dtd Cgl1924 Cgl1924 cg2132 cg2132 rpsO rpsO ribF ribF Cgl1983 Cgl1983 Cgl1997 Cgl1997 selO selO Cgl2012 Cgl2012 rpsB rpsB xerC xerC rplS rplS Cgl2053 Cgl2053 rpsP rpsP smc smc Cgl2067 Cgl2067 hipO hipO Cgl2129 Cgl2129 Cgl2133 Cgl2133 Cgl2135 Cgl2135 pknL pknL plsC plsC Cgl2203 Cgl2203 Cgl2216 Cgl2216 hmuO hmuO Cgl2230 Cgl2230 Cgl2241 Cgl2241 Cgl2257 Cgl2257 Cgl2266 Cgl2266 dnaG dnaG Cgl2281 Cgl2281 Cgl2282 Cgl2282 recO recO ybeY ybeY fadD15 fadD15 rpsT rpsT nadD nadD obg obg rplU rplU Cgl2366 Cgl2366 Cgl2368 Cgl2368 folC folC Cgl2379 Cgl2379 Cgl2394 Cgl2394 Cgl2399 Cgl2399 crtI crtI crtI-2 crtI-2 crtB crtB Cgl2442 Cgl2442 Cgl2462 Cgl2462 Cgl2486 Cgl2486 Cgl2508 Cgl2508 dinG dinG rpmJ rpmJ Cgl2553 Cgl2553 pduO pduO actA actA Cgl2579 Cgl2579 purF purF Cgl2585 Cgl2585 Cgl2586 Cgl2586 purD purD ptsS ptsS clpC clpC folK folK ptsX-2 ptsX-2 Cgl2721 Cgl2721 Cgl2727 Cgl2727 Cgl2755 Cgl2755 Cgl2767 Cgl2767 clpB clpB Cgl2783 Cgl2783 Cgl2795 Cgl2795 Cgl2804 Cgl2804 Cgl2813 Cgl2813 cg3117 cg3117 Cgl2833 Cgl2833 Cgl2840 Cgl2840 pck pck Cgl2876 Cgl2876 psp5 psp5 pheA pheA Cgl2914 Cgl2914 lldA lldA Cgl2924 Cgl2924 Cgl2955 Cgl2955 cg3273 cg3273 Cgl2960 Cgl2960 trxB1 trxB1 dnaB dnaB rpsF rpsF Cgl2994 Cgl2994 ogt ogt hpaG hpaG qcrA2 qcrA2 Cgl3064 Cgl3064 Cgl3071 Cgl3071 parB parB parA1 parA1 recF recF gyrB gyrB Cgl0018 Cgl0018 Cgl0033 Cgl0033 pknB pknB bioB bioB Cgl0079 Cgl0079 Cgl0102 Cgl0102 Cgl0120 Cgl0120 Cgl0144 Cgl0144 Cgl0149 Cgl0149 gltB gltB Cgl0202 Cgl0202 Cgl0223 Cgl0223 mgtE2 mgtE2 tadA tadA Cgl0243 Cgl0243 recR recR leuA leuA katA katA Cgl0276 Cgl0276 fadD1 fadD1 fadE fadE nth nth Cgl0295 Cgl0295 Cgl0301 Cgl0301 Cgl0302 Cgl0302 Cgl0303 Cgl0303 Cgl0307 Cgl0307 topA topA Cgl0315 Cgl0315 Cgl0326 Cgl0326 Cgl0380 Cgl0380 Cgl0381 Cgl0381 deoC deoC fadD5 fadD5 hemA hemA Cgl0425 Cgl0425 hemY hemY ccsA ccsA ccsB ccsB Cgl0472 Cgl0472 rplK rplK rplA rplA Cgl0483 Cgl0483 rplJ rplJ rplL rplL rpsL rpsL rpsG rpsG Cgl0503 Cgl0503 rpsJ rpsJ rplC rplC rplD rplD rplW rplW rplB rplB rpsS rpsS rplV rplV rpsC rpsC rplP rplP rpmC rpmC rpsQ rpsQ rplN rplN rplX rplX rplE rplE rpsH rpsH rplF rplF rplR rplR rpsE rpsE rpmD rpmD rplO rplO rpsM rpsM rpsK rpsK rpsD rpsD rplQ rplQ truA truA rplM rplM rpsI rpsI crtYf crtYf crtI2 crtI2 crtB2 crtB2 Cgl0633 Cgl0633 cobB cobB Cgl0645 Cgl0645 metY metY
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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rpmH50S RIBOSOMAL PROTEIN L34; Belongs to the bacterial ribosomal protein bL34 family. (47 aa)
prpB2PROBABLE METHYLISOCITRIC ACID LYASE; Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2- methylisocitrate to yield pyruvate and succinate via an alpha-carboxy- carbanion intermediate; Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (307 aa)
Cgl0679Membrane protein. (301 aa)
pmmBPHOSPHOGLUCOMUTASE/PHOSPHOMANNOMUTASE. (530 aa)
amiAPUTATIVE N-ACYL-L-AMINO ACID AMIDOHYDROLASE. (395 aa)
prpB1PROBABLE METHYLISOCITRIC ACID LYASE; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate. (305 aa)
Cgl0731Helicase. (1600 aa)
Cgl0733Conserved hypothetical protein. (217 aa)
Cgl0737Helicase. (2100 aa)
Cgl0739Superfamily II DNA/RNA helicase, SNF2 family. (962 aa)
hpfRibosome-associated protein Y (PSrp-1); Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. (221 aa)
Cgl0765Uncharacterized ACR, COG2135; Belongs to the SOS response-associated peptidase family. (213 aa)
rhlEPROBABLE ATP-DEPENDENT RNA HELICASE PROTEIN; Belongs to the DEAD box helicase family. (424 aa)
Cgl0778NTP pyrophosphohydrolase. (238 aa)
pdxSPyridoxine biosynthesis enzyme; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. (299 aa)
Cgl0809Membrane protein. (196 aa)
Cgl0822GLUTAMINE CYCLOTRANSFERASE PRECURSOR. (258 aa)
serCPhosphoserine Transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (376 aa)
Cgl0856ABC-type transport system, involved in lipoprotein release, ATPase component. (222 aa)
rpsR30S RIBOSOMAL PROTEIN S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (83 aa)
rpsN30S RIBOSOMAL PROTEIN S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa)
rpmG50S RIBOSOMAL PROTEIN L33; Belongs to the bacterial ribosomal protein bL33 family. (54 aa)
rpmB50S RIBOSOMAL PROTEIN L28; Belongs to the bacterial ribosomal protein bL28 family. (78 aa)
rpmEPROBABLE 50S RIBOSOMAL SUBUNIT PROTEIN L31. (88 aa)
rpmFRibosomal L32p protein family; Belongs to the bacterial ribosomal protein bL32 family. (57 aa)
pmtDolichyl-phosphate-mannose-protein mannosyltransferase; Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins; Belongs to the glycosyltransferase 39 family. (520 aa)
Cgl0894PROBABLE ATP-DEPENDENT DNA HELICASE PROTEIN. (683 aa)
Cgl0896Double-stranded beta-helix domain. (386 aa)
ispEPUTATIVE ISOPENTENYL MONOPHOSPHATE KINASE; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (311 aa)
Cgl0919Enoyl-CoA hydratase/carnithine racemase. (339 aa)
Cgl0928Conserved hypothetical protein. (517 aa)
rplYRibosomal protein L25 (general stress protein Ctc); This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (200 aa)
pabABPARA-AMINOBENZOATE SYNTHASE COMPONENT I and II. (620 aa)
Cgl1014NADPH-dependent FMN reductase. (188 aa)
ssiFPUTATIVE MONOXYGENASE. (360 aa)
ssiGPUTATIVE MONOXYGENASE. (399 aa)
ychFPredicted GTPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (361 aa)
Cgl1036Short chain dehydrogenase. (185 aa)
Cgl1057Mg-chelatase subunit ChlI. (457 aa)
Cgl1059Strong similarity to hypothetical protein Rv2133c-Mycobacterium tuberculosis. (235 aa)
Cgl1060PEP phosphonomutase or related enzyme. (231 aa)
Cgl1067Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme. (358 aa)
Cgl1072Predicted Zn-dependent hydrolase of the beta-lactamase fold. (209 aa)
Cgl1081Adenylate kinase or related kinase. (177 aa)
cg1241Hypothetical protein predicted by Glimmer/Critica. (87 aa)
Cgl1105HNH endonuclease. (395 aa)
mgtE1Mg/Co/Ni transporter MgtE (contains CBS domain) intracellular. (430 aa)
Cgl1126Conserved hypothetical membrane protein. (165 aa)
metEHomocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (745 aa)
deaDSuperfamily II DNA and RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (732 aa)
Cgl1164Superfamily II DNA/RNA helicases, SNF2 family. (1034 aa)
Cgl1166DNA repair exonuclease. (391 aa)
lysADIAMINOPIMELATE DECARBOXYLASE; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (445 aa)
fadD4ACYL-COA SYNTHETASE. (575 aa)
fixBPUTATIVE ELECTRON TRANSFER FLAVOPROTEIN, ALPHA SUBUNIT. (317 aa)
nifS1PROBABLE PYRIDOXAL-PHOSPHATE-DEPENDENT AMINOTRANSFERASE/CYSTEINE DESULFINASE. (376 aa)
Cgl1236Acetyltransferase, GNAT family. (168 aa)
Cgl1260Putative dinucleotide-binding enzyme. (192 aa)
Cgl1264PUTATIVE GLUTATHIONE S-TRANSFERASE. (359 aa)
Cgl1278Acyl-CoA dehydrogenase family protein (N-terminal fragment). (144 aa)
Cgl1279Acyl-CoA dehydrogenase family protein (C-terminal fragment). (123 aa)
Cgl1281Co/Zn/Cd efflux system transmembrane protein. (324 aa)
Cgl12902-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE. (268 aa)
entCISOCHORISMATE SYNTHASE. (376 aa)
rpsA30S RIBOSOMAL PROTEIN S1. (486 aa)
ptsGGLUCOSE-SPECIFIC ENZYME II BC COMPONENT OF PTS; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in mannose transport. (683 aa)
rpmI50S RIBOSOMAL PROTEIN L35; Belongs to the bacterial ribosomal protein bL35 family. (64 aa)
rplT50S RIBOSOMAL PROTEIN L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (127 aa)
argCN-ACETYL-GAMMA-GLUTAMYL-PHOSPHATE REDUCTASE; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (357 aa)
argBACETYLGLUTAMATE KINASE; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (317 aa)
Cgl1409Conserved hypothetical protein. (228 aa)
recNDNA REPAIR PROTEIN RECN; May be involved in recombinational repair of damaged DNA. (593 aa)
parA2PUTATIVE CHROMOSOME PARTITIONING ATPASE PROTEIN. (290 aa)
Cgl1450Superfamily II DNA or RNA helicase. (448 aa)
Cgl1489Superfamily II DNA and RNA helicase. (929 aa)
mcmBMETHYLMALONYL-COA MUTASE LARGE SUBUNIT. (737 aa)
mcmAMETHYLMALONYL-COA MUTASE SMALL SUBUNIT. (616 aa)
hemHFERROCHELATASE PRECURSOR; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (370 aa)
Cgl1547Putative signal recognition particle GTPase. (158 aa)
nifS2CYSTEINE DESULFHYDRASE / SELENOCYSTEINE LYASE; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (421 aa)
sufCIron-regulated ABC transporter ATPase subunit. (252 aa)
sufDComponents of an uncharacterized iron-regulated ABC-type transporter. (392 aa)
sufBComponent of an uncharacterized iron-regulated ABC-type transporter. (481 aa)
ctaACytochrome oxidase assembly protein. (346 aa)
ocdPROBABLE ORNITHINE CYCLODEAMINASE PROTEIN. (382 aa)
gapGLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. (334 aa)
priAPrimosomal protein N' (replication factor Y)-superfamily II helicase; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (688 aa)
ihfPutative integration host factor cIHF. (106 aa)
Cgl1631Predicted endonuclease involved in recombination; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. (182 aa)
Cgl1633Uncharacterized ATPase related to the helicase subunit of the Holliday junction resolvase. (472 aa)
Cgl1634Conserved hypothetical protein. (399 aa)
Cgl1637Superfamily II DNA/RNA helicase, SNF2 family. (892 aa)
tesB2PROBABLE ACYL-COA THIOESTERASE II PROTEIN. (282 aa)
priPPROPHAGE DNA PRIMASE. (591 aa)
Cgl1743Superfamily II DNA/RNA helicase. (613 aa)
Cgl1758MoxR-like ATPase. (419 aa)
Cgl1760ATPase with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. (655 aa)
Cgl1783Conserved hypothetical protein. (117 aa)
Cgl1790PUTATIVE CLP-FAMILY ATP-BINDING PROTEASE. (595 aa)
Cgl1843DNA TOPOISOMERASE I (OMEGA-PROTEIN). (759 aa)
dtdPutative D-Tyr-tRNAtyr deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (144 aa)
Cgl1924Superfamily II DNA or RNA helicase. (850 aa)
cg2132Conserved hypothetical protein. (453 aa)
rpsORIBOSOMAL PROTEIN S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (89 aa)
ribFPUTATIVE RIBOFLAVIN KINASE; Belongs to the ribF family. (341 aa)
Cgl1983Exopolyphosphatase-related protein. (332 aa)
Cgl1997Mg-chelatase subunit I. (367 aa)
selOConserved hypothetical protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). (474 aa)
Cgl2012ABC-type transport system, involved in lipoprotein release, ATPase component. (230 aa)
rpsB30S RIBOSOMAL PROTEIN S2; Belongs to the universal ribosomal protein uS2 family. (272 aa)
xerCSITE-SPECIFIC RECOMBINASE; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (315 aa)
rplS50S RIBOSOMAL PROTEIN L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (113 aa)
Cgl2053Double-stranded beta-helix domain. (116 aa)
rpsP30S RIBOSOMAL PROTEIN S16; Belongs to the bacterial ribosomal protein bS16 family. (165 aa)
smcChromosome segregation ATPase; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1155 aa)
Cgl2067Putative membrane protein. (618 aa)
hipOPUTATIVE HIPPURATE HYDROLASE PROTEIN. (421 aa)
Cgl2129Similar to methionine synthase II (cobalamin-independent). (405 aa)
Cgl2133Predicted Co/Zn/Cd cation transporter. (328 aa)
Cgl2135Decarboxylase. (884 aa)
pknLPUTATIVE SERINE/THREONINE PROTEIN KINASE. (740 aa)
plsC1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACETYLTRANSFERASE. (267 aa)
Cgl2203SHORT CHAIN DEHYDROGENASE; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (238 aa)
Cgl2216PUTATIVE TRANSCRIPTIONAL REGULATOR. (133 aa)
hmuOPROBABLE HEME OXYGENASE. (215 aa)
Cgl2230Conserved hypothetical protein. (368 aa)
Cgl2241Putative membrane protein. (333 aa)
Cgl2257ATPase component of ABC transporters with duplicated ATPase domains. (344 aa)
Cgl2266Conserved hypothetical protein. (612 aa)
dnaGDNA PRIMASE; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. (633 aa)
Cgl2281Conserved hypothetical protein. (517 aa)
Cgl2282Putative membrane protein. (357 aa)
recORecombinational DNA repair protein (RecF pathway); Involved in DNA repair and RecF pathway recombination. (242 aa)
ybeYPredicted metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (196 aa)
fadD15LONG-CHAIN FATTY ACID COA LIGASE. (615 aa)
rpsT30S RIBOSOMAL PROTEIN S20; Binds directly to 16S ribosomal RNA. (87 aa)
nadDPUTATIVE NICOTINIC ACID MONONUCLEOTIDE ADENYLYLTRANSFERASE; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (226 aa)
obgPredicted GTPase; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (501 aa)
rplURIBOSOMAL PROTEIN L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (101 aa)
Cgl2366Pirin-related protein-fragment; Belongs to the pirin family. (203 aa)
Cgl2368Pirin-related protein-fragment. (126 aa)
folCFOLYLPOLYGLUTAMATE SYNTHASE; Belongs to the folylpolyglutamate synthase family. (507 aa)
Cgl2379Predicted Rossmann fold nucleotide-binding protein; Belongs to the LOG family. (195 aa)
Cgl2394ATP-dependent transcriptional regulator, LuxR family. (687 aa)
Cgl2399Putative restriction endonuclease. (386 aa)
crtIPHYTOENE DESATURASE (C-terminal fragment). (109 aa)
crtI-2PHYTOENE DEHYDROGENASE (DESATURASE) (N-terminal fragment). (395 aa)
crtBPHYTOENE SYNTHETASE. (287 aa)
Cgl2442Conserved hypothetical protein. (517 aa)
Cgl2462Conserved hypothetical protein. (414 aa)
Cgl2486HNH nuclease. (388 aa)
Cgl2508Metal-dependent hydrolases of the beta-lactamase superfamily III. (255 aa)
dinGPROBABLE ATP-DEPENDENT DNA HELICASE-RELATED PROTEIN. (625 aa)
rpmJRibosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. (40 aa)
Cgl2553ABC-type transport system, involved in lipoprotein release, ATPase component. (284 aa)
pduOADENOSYLCOBALAMIN-DEPENDENT DIOL DEHYDRATASE GAMMA; Belongs to the Cob(I)alamin adenosyltransferase family. (190 aa)
actABUTYRYL-COA:ACETATE COENZYME A TRANSFERASE. (502 aa)
Cgl2579Conserved hypothetical protein; May play a role in the intracellular transport of hydrophobic ligands. (229 aa)
purFAMIDOPHOSPHORIBOSYLTRANSFERASE; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (494 aa)
Cgl2585Conserved hypothetical protein. (125 aa)
Cgl2586PUTATIVE ACYL-COA THIOESTER HYDROLASE PROTEIN. (339 aa)
purDPHOSPHORIBOSYLAMINE-GLYCINE LIGASE. (421 aa)
ptsSENZYME II SUCROSE PROTEIN. (661 aa)
clpCPROBABLE ATP-DEPENDENT PROTEASE (HEAT SHOCK PROTEIN); Belongs to the ClpA/ClpB family. (925 aa)
folK7, 8-DIHYDRO-6-HYDROXYMETHYLPTERIN-PYROPHOSPHOKINASE. (159 aa)
ptsX-2Phosphotransferase system IIC components-fragment. (83 aa)
Cgl2721Hypothetical protein predicted by Glimmer/Critica. (818 aa)
Cgl2727Acetyl-CoA acetyltransferase. (186 aa)
Cgl2755Acyltransferase. (182 aa)
Cgl2767Conserved hypothetical protein. (256 aa)
clpBPROBABLE ATP-DEPENDENT PROTEASE (HEAT SHOCK PROTEIN); Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity). Necessary [...] (852 aa)
Cgl2783Predicted Co/Zn/Cd cation transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (340 aa)
Cgl2795Conserved hypothetical protein. (378 aa)
Cgl2804ATPase involved in DNA repair. (1111 aa)
Cgl2813Conserved hypothetical protein. (241 aa)
cg3117Conserved hypothetical protein. (82 aa)
Cgl2833Putative membrane protein. (262 aa)
Cgl2840Putative secreted protein. (208 aa)
pckPROBABLE PHOSPHOENOLPYRUVATE CARBOXYKINASE PROTEIN; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (610 aa)
Cgl2876Conserved hypothetical protein. (457 aa)
psp5Putative secreted protein. (706 aa)
pheAPREPHENATE DEHYDRATASE. (315 aa)
Cgl2914NADPH-dependent FMN reductase. (181 aa)
lldAPUTATIVE L-LACTATE DEHYDROGENASE. (420 aa)
Cgl2924Metal-dependent amidase/aminoacylase/carboxypeptidase. (134 aa)
Cgl2955Putative membrane protein. (240 aa)
cg3273Hypothetical protein predicted by Glimmer. (98 aa)
Cgl2960Uncharacterized ACR, double-stranded beta-helix domain. (111 aa)
trxB1THIOREDOXIN. (124 aa)
dnaBPUTATIVE REPLICATIVE DNA HELICASE; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (510 aa)
rpsFRIBOSOMAL PROTEIN S6; Binds together with S18 to 16S ribosomal RNA. (95 aa)
Cgl2994ABC-type transport system, involved in lipoprotein release, ATPase component. (230 aa)
ogtMETHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (158 aa)
hpaG2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (Catechol pathway); PUTATIVE BIFUNCTIONAL ENZYME 2-HYDROXYHEPTA-2,4-DIENE-1, 7-DIOATESOMERASE5-CARBOXYMETHYL-2-OXO-HEX-3. (279 aa)
qcrA2RIESKE IRON-SULFUR PROTEIN. (150 aa)
Cgl3064Putative secreted phosphoesterase. (1461 aa)
Cgl3071Hypothetical protein predicted by Glimmer. (83 aa)
parBPredicted transcriptional regulator involved in chromosome patitioning; Belongs to the ParB family. (379 aa)
parA1ATPases involved in chromosome partitioning. (307 aa)
recFDNA REPAIR AND GENETIC RECOMBINATION PROTEIN; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (394 aa)
gyrBDNA GYRASE SUBUNIT B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (684 aa)
Cgl0018PUTATIVE INTEGRAL MEMBRANE CYTOCHROME BIOGENESIS PROTEIN. (290 aa)
Cgl0033Conserved hypothetical protein. (270 aa)
pknBEUKARYOTIC-TYPE SERINE/THREONINE KINASE; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (646 aa)
bioBBIOTIN SYNTHASE; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (334 aa)
Cgl0079PUTATIVE SIR2-LIKE REGULATORY PROTEIN. (277 aa)
Cgl0102HYDROLASE, AMA/HIPO/HYUC FAMILY; Belongs to the peptidase M20A family. (462 aa)
Cgl0120PUTATIVE ACETYLTRANSFERASE. (186 aa)
Cgl0144PUTATIVE DNA REPAIR PROTEIN. (230 aa)
Cgl0149Methylated-DNA--protein-cysteine methyltransferase. (114 aa)
gltBGLUTAMINE 2-OXOGLUTARATE AMINOTRANSFERASE LARGE SU. (1510 aa)
Cgl0202AMINOTRANSFERASE. (401 aa)
Cgl0223PUTATIVE OXIDOREDUCTASE PROTEIN. (267 aa)
mgtE2MG2+ TRANSPORTER; Acts as a magnesium transporter. (436 aa)
tadAPUTATIVE CYTOSINE DEAMINASE; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (143 aa)
Cgl0243Uncharacterized BCR, YbaB family COG0718; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. (103 aa)
recRDNA repair protein (RecF pathway); May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (218 aa)
leuA2-ISOPROPYLMALATE SYNTHASE; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (616 aa)
katACATALASE. (516 aa)
Cgl0276Secreted phosphohydrolase. (305 aa)
fadD1PUTATIVE FATTY-ACID--COA LIGASE TRANSMEMBRANE PROTEIN. (510 aa)
fadEGLUTARYL-COA DEHYDROGENASE. (398 aa)
nthPROBABLE ENDONUCLEASE III PROTEIN; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (260 aa)
Cgl0295Pyrophosphohydrolase. (259 aa)
Cgl0301PROBABLE SECRETION ATPASE PROTEIN. (377 aa)
Cgl0302Membrane protein. (258 aa)
Cgl0303Membrane protein. (191 aa)
Cgl0307DEAD/DEAH box helicase. (798 aa)
topADNA TOPOISOMERASE; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...] (996 aa)
Cgl0315Adenylate kinase or related kinase. (187 aa)
Cgl0326Hypothetical protein. (343 aa)
Cgl0380Permease, major facilitator superfamily. (549 aa)
Cgl0381Permease, major facilitator superfamily. (544 aa)
deoCDEOXYRIBOSE-PHOSPHATE ALDOLASE; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (222 aa)
fadD5LONG-CHAIN-FATTY-ACID-COA LIGASE. (568 aa)
hemAGLUTAMYL-TRNA REDUCTASE; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (463 aa)
Cgl0425Putative ribosomal protein L7/L12 family. (91 aa)
hemYPUTATIVE PROTOPORPHYRINOGEN OXIDASE; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (448 aa)
ccsACytochrome c biogenesis protein transmembrane prot. (268 aa)
ccsBCytochrome c assembly membrane protein. (337 aa)
Cgl0472MONOOXYGENASE, FAD-BINDING, PUTATIVE. (424 aa)
rplK50S RIBOSOMAL PROTEIN L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (145 aa)
rplA50S RIBOSOMAL PROTEIN L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (236 aa)
Cgl0483PUTATIVE DEHYDROGENASE. (471 aa)
rplJ50S RIBOSOMAL PROTEIN L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (171 aa)
rplLPROBABLE 50S RIBOSOMAL SUBUNIT PROTEIN L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (128 aa)
rpsLRIBOSOMAL PROTEIN S12; With S4 and S5 plays an important role in translational accuracy. (122 aa)
rpsG30S RIBOSOMAL PROTEIN S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (155 aa)
Cgl0503PUTATIVE BUTYRYL-COA:ACETATE COENZYME A TRANSFERAS. (172 aa)
rpsJRIBOSOMAL PROTEIN S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (110 aa)
rplC50S RIBOSOMAL PROTEIN L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (218 aa)
rplD50S RIBOSOMAL PROTEIN L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (218 aa)
rplW50S RIBOSOMAL PROTEIN L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (101 aa)
rplB50S RIBOSOMAL PROTEIN L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (280 aa)
rpsS30S RIBOSOMAL PROTEIN S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa)
rplVRIBOSOMAL PROTEIN L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). (120 aa)
rpsC30S RIBOSOMAL PROTEIN S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (248 aa)
rplP50S RIBOSOMAL PROTEIN L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (138 aa)
rpmC50S RIBOSOMAL PROTEIN L29; Belongs to the universal ribosomal protein uL29 family. (76 aa)
rpsQ30S RIBOSOMAL PROTEIN S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (92 aa)
rplN50S RIBOSOMAL PROTEIN L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
rplX50S RIBOSOMAL PROTEIN L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (104 aa)
rplE50S RIBOSOMAL PROTEIN L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (191 aa)
rpsHRIBOSOMAL PROTEIN S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa)
rplF50S RIBOSOMAL PROTEIN L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (178 aa)
rplR50S RIBOSOMAL PROTEIN L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (134 aa)
rpsE30S RIBOSOMAL PROTEIN S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. (211 aa)
rpmD50S RIBOSOMAL PROTEIN L30. (61 aa)
rplORIBOSOMAL PROTEIN L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (148 aa)
rpsMRIBOSOMAL PROTEIN S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (122 aa)
rpsKRIBOSOMAL PROTEIN S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (134 aa)
rpsDRIBOSOMAL PROTEIN S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (201 aa)
rplQ50S RIBOSOMAL PROTEIN L17. (163 aa)
truAPROBABLE TRNA PSEUDOURIDINE SYNTHASE A PROTEIN; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (294 aa)
rplMRIBOSOMAL PROTEIN L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (147 aa)
rpsI30S RIBOSOMAL PROTEIN S9; Belongs to the universal ribosomal protein uS9 family. (182 aa)
crtYfC50 CAROTENOID EPSILON CYCLASE. (130 aa)
crtI2PHYTOENE DEHYDROGENASE (DESATURASE). (549 aa)
crtB2PHYTOENE SYNTHETASE. (304 aa)
Cgl0633PUTATIVE ABC TRANSPORTER ATP-BINDING PROTEIN. (239 aa)
cobBProtein deacetylase, SIR2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily. (258 aa)
Cgl0645Cytidine and deoxycytidylate deaminase. (164 aa)
metYO-Acetylhomoserine (Thiol)-Lyase; Catalyzes the conversion of O-acetyl-L-homoserine (OAH) into homocysteine in the methionine biosynthesis pathway (Ref.4,. Can also use dimethyldisulfide and methanethiol as reduced sulfur sources, leading to the direct formation of methionine. Has weak cystathionine gamma-synthase activity. (437 aa)
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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