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| | recF | DNA REPAIR AND GENETIC RECOMBINATION PROTEIN; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (394 aa) |
| | gyrB | DNA GYRASE SUBUNIT B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (684 aa) |
| | pknB | EUKARYOTIC-TYPE SERINE/THREONINE KINASE; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (646 aa) |
| | Cgl0079 | PUTATIVE SIR2-LIKE REGULATORY PROTEIN. (277 aa) |
| | Cgl0120 | PUTATIVE ACETYLTRANSFERASE. (186 aa) |
| | Cgl0243 | Uncharacterized BCR, YbaB family COG0718; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. (103 aa) |
| | recR | DNA repair protein (RecF pathway); May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (218 aa) |
| | katA | CATALASE. (516 aa) |
| | Cgl0276 | Secreted phosphohydrolase. (305 aa) |
| | nth | PROBABLE ENDONUCLEASE III PROTEIN; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (260 aa) |
| | Cgl0301 | PROBABLE SECRETION ATPASE PROTEIN. (377 aa) |
| | Cgl0302 | Membrane protein. (258 aa) |
| | Cgl0303 | Membrane protein. (191 aa) |
| | topA | DNA TOPOISOMERASE; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...] (996 aa) |
| | Cgl0425 | Putative ribosomal protein L7/L12 family. (91 aa) |
| | ccsB | Cytochrome c assembly membrane protein. (337 aa) |
| | Cgl0483 | PUTATIVE DEHYDROGENASE. (471 aa) |
| | rplJ | 50S RIBOSOMAL PROTEIN L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (171 aa) |
| | rplL | PROBABLE 50S RIBOSOMAL SUBUNIT PROTEIN L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (128 aa) |
| | rpsG | 30S RIBOSOMAL PROTEIN S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (155 aa) |
| | rpsJ | RIBOSOMAL PROTEIN S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (110 aa) |
| | rplC | 50S RIBOSOMAL PROTEIN L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (218 aa) |
| | rplW | 50S RIBOSOMAL PROTEIN L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (101 aa) |
| | rplB | 50S RIBOSOMAL PROTEIN L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (280 aa) |
| | rpsC | 30S RIBOSOMAL PROTEIN S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (248 aa) |
| | rpmC | 50S RIBOSOMAL PROTEIN L29; Belongs to the universal ribosomal protein uL29 family. (76 aa) |
| | rpsQ | 30S RIBOSOMAL PROTEIN S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (92 aa) |
| | rplN | 50S RIBOSOMAL PROTEIN L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa) |
| | rplX | 50S RIBOSOMAL PROTEIN L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (104 aa) |
| | rplE | 50S RIBOSOMAL PROTEIN L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (191 aa) |
| | rpsH | RIBOSOMAL PROTEIN S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rplR | 50S RIBOSOMAL PROTEIN L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (134 aa) |
| | rpsE | 30S RIBOSOMAL PROTEIN S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. (211 aa) |
| | rpmD | 50S RIBOSOMAL PROTEIN L30. (61 aa) |
| | rplO | RIBOSOMAL PROTEIN L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (148 aa) |
| | rpsK | RIBOSOMAL PROTEIN S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (134 aa) |
| | rplQ | 50S RIBOSOMAL PROTEIN L17. (163 aa) |
| | rplM | RIBOSOMAL PROTEIN L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (147 aa) |
| | rpsI | 30S RIBOSOMAL PROTEIN S9; Belongs to the universal ribosomal protein uS9 family. (182 aa) |
| | crtI2 | PHYTOENE DEHYDROGENASE (DESATURASE). (549 aa) |
| | cobB | Protein deacetylase, SIR2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily. (258 aa) |
| | hpf | Ribosome-associated protein Y (PSrp-1); Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. (221 aa) |
| | Cgl0765 | Uncharacterized ACR, COG2135; Belongs to the SOS response-associated peptidase family. (213 aa) |
| | rhlE | PROBABLE ATP-DEPENDENT RNA HELICASE PROTEIN; Belongs to the DEAD box helicase family. (424 aa) |
| | pdxS | Pyridoxine biosynthesis enzyme; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. (299 aa) |
| | rpsR | 30S RIBOSOMAL PROTEIN S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (83 aa) |
| | rpsN | 30S RIBOSOMAL PROTEIN S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa) |
| | rpmG | 50S RIBOSOMAL PROTEIN L33; Belongs to the bacterial ribosomal protein bL33 family. (54 aa) |
| | rpmB | 50S RIBOSOMAL PROTEIN L28; Belongs to the bacterial ribosomal protein bL28 family. (78 aa) |
| | rpmE | PROBABLE 50S RIBOSOMAL SUBUNIT PROTEIN L31. (88 aa) |
| | rpmF | Ribosomal L32p protein family; Belongs to the bacterial ribosomal protein bL32 family. (57 aa) |
| | Cgl0894 | PROBABLE ATP-DEPENDENT DNA HELICASE PROTEIN. (683 aa) |
| | rplY | Ribosomal protein L25 (general stress protein Ctc); This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (200 aa) |
| | deaD | Superfamily II DNA and RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (732 aa) |
| | rpsA | 30S RIBOSOMAL PROTEIN S1. (486 aa) |
| | rpmI | 50S RIBOSOMAL PROTEIN L35; Belongs to the bacterial ribosomal protein bL35 family. (64 aa) |
| | rplT | 50S RIBOSOMAL PROTEIN L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (127 aa) |
| | Cgl1409 | Conserved hypothetical protein. (228 aa) |
| | recN | DNA REPAIR PROTEIN RECN; May be involved in recombinational repair of damaged DNA. (593 aa) |
| | parA2 | PUTATIVE CHROMOSOME PARTITIONING ATPASE PROTEIN. (290 aa) |
| | Cgl1450 | Superfamily II DNA or RNA helicase. (448 aa) |
| | Cgl1489 | Superfamily II DNA and RNA helicase. (929 aa) |
| | priA | Primosomal protein N' (replication factor Y)-superfamily II helicase; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (688 aa) |
| | Cgl1633 | Uncharacterized ATPase related to the helicase subunit of the Holliday junction resolvase. (472 aa) |
| | priP | PROPHAGE DNA PRIMASE. (591 aa) |
| | Cgl1758 | MoxR-like ATPase. (419 aa) |
| | Cgl1843 | DNA TOPOISOMERASE I (OMEGA-PROTEIN). (759 aa) |
| | dtd | Putative D-Tyr-tRNAtyr deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (144 aa) |
| | Cgl1924 | Superfamily II DNA or RNA helicase. (850 aa) |
| | cg2132 | Conserved hypothetical protein. (453 aa) |
| | rpsO | RIBOSOMAL PROTEIN S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (89 aa) |
| | Cgl1983 | Exopolyphosphatase-related protein. (332 aa) |
| | rpsB | 30S RIBOSOMAL PROTEIN S2; Belongs to the universal ribosomal protein uS2 family. (272 aa) |
| | rpsP | 30S RIBOSOMAL PROTEIN S16; Belongs to the bacterial ribosomal protein bS16 family. (165 aa) |
| | smc | Chromosome segregation ATPase; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1155 aa) |
| | pknL | PUTATIVE SERINE/THREONINE PROTEIN KINASE. (740 aa) |
| | Cgl2203 | SHORT CHAIN DEHYDROGENASE; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (238 aa) |
| | Cgl2257 | ATPase component of ABC transporters with duplicated ATPase domains. (344 aa) |
| | dnaG | DNA PRIMASE; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. (633 aa) |
| | recO | Recombinational DNA repair protein (RecF pathway); Involved in DNA repair and RecF pathway recombination. (242 aa) |
| | rpsT | 30S RIBOSOMAL PROTEIN S20; Binds directly to 16S ribosomal RNA. (87 aa) |
| | obg | Predicted GTPase; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (501 aa) |
| | rplU | RIBOSOMAL PROTEIN L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (101 aa) |
| | Cgl2394 | ATP-dependent transcriptional regulator, LuxR family. (687 aa) |
| | crtI | PHYTOENE DESATURASE (C-terminal fragment). (109 aa) |
| | crtI-2 | PHYTOENE DEHYDROGENASE (DESATURASE) (N-terminal fragment). (395 aa) |
| | Cgl2462 | Conserved hypothetical protein. (414 aa) |
| | rpmJ | Ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. (40 aa) |
| | pduO | ADENOSYLCOBALAMIN-DEPENDENT DIOL DEHYDRATASE GAMMA; Belongs to the Cob(I)alamin adenosyltransferase family. (190 aa) |
| | Cgl2721 | Hypothetical protein predicted by Glimmer/Critica. (818 aa) |
| | Cgl2795 | Conserved hypothetical protein. (378 aa) |
| | Cgl2804 | ATPase involved in DNA repair. (1111 aa) |
| | Cgl2833 | Putative membrane protein. (262 aa) |
| | psp5 | Putative secreted protein. (706 aa) |
| | dnaB | PUTATIVE REPLICATIVE DNA HELICASE; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (510 aa) |
| | rpsF | RIBOSOMAL PROTEIN S6; Binds together with S18 to 16S ribosomal RNA. (95 aa) |
| | qcrA2 | RIESKE IRON-SULFUR PROTEIN. (150 aa) |
| | parB | Predicted transcriptional regulator involved in chromosome patitioning; Belongs to the ParB family. (379 aa) |
| | parA1 | ATPases involved in chromosome partitioning. (307 aa) |
| | rpmH | 50S RIBOSOMAL PROTEIN L34; Belongs to the bacterial ribosomal protein bL34 family. (47 aa) |
