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pbpA pbpA crgA crgA murA2 murA2 tig tig ftsI ftsI murE murE murF murF mraY mraY ftsW ftsW murG murG murC murC ftsQ ftsQ ftsZ ftsZ sepF sepF Cgl2150 Cgl2150 xerC xerC pbp pbp ftsK ftsK whiA whiA Cgl1425 Cgl1425 Cgl1422 Cgl1422 xerD xerD ftsX ftsX ftsE ftsE murB2 murB2 murB murB rodA rodA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pbpAD-ALANYL-D-ALANINE CARBOXYPEPTIDASE. (474 aa)
crgAPutative membrane protein; Involved in cell division; Belongs to the CrgA family. (90 aa)
murA2UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (421 aa)
tigTRIGGER FACTOR, PPIASE INVOVED INTO CELL DIVISION, MOLECULAR CHAPERONE; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (449 aa)
ftsIPENICILLIN-BINDING PROTEIN 2X. (651 aa)
murEPROBABLE UDP-N-ACETYLMURAMOYLALANYL-D-GLUTAMATE--2; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (521 aa)
murFD-ALANINE:D-ALANINE-ADDING ENZYME; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (514 aa)
mraYPHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE- TRANSFERASE; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (366 aa)
ftsWBacterial cell division membrane protein; Belongs to the SEDS family. (550 aa)
murGPeptidoglycan biosynthesis protein; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (363 aa)
murCPROBABLE UDP-N-ACETYLMURAMATE--ALANINE LIGASE PROTEIN; Cell wall formation; Belongs to the MurCDEF family. (486 aa)
ftsQCell division septal protein; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. (222 aa)
ftsZCell division GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (442 aa)
sepFConserved hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (152 aa)
Cgl2150Cell division initiation protein-Antigen 84 homolog. (365 aa)
xerCSITE-SPECIFIC RECOMBINASE; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (315 aa)
pbpPENICILLIN-BINDING PROTEIN, PUTATIVE D-ALANYL-D-ALANINE CARBOXYPEPTIDASE. (622 aa)
ftsKCELL DIVISION PROTEIN, REQUIRED FOR CELL DIVISION AND CHROMOSOMEPARTITIONING; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity). Belongs to the FtsK/SpoIIIE/SftA family. (1010 aa)
whiAPutative transcriptional regulator-WhiA homolog; Involved in cell division and chromosome segregation. (327 aa)
Cgl1425CONSERVED HYPOTHETICAL PROTEIN; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (171 aa)
Cgl1422CONSERVED HYPOTHETICAL PROTEIN; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. (255 aa)
xerDINTEGRASE/RECOMBINASE XERD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (304 aa)
ftsXPUTATIVE CELL DIVISION PROTEIN; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (300 aa)
ftsECELL DIVISION ATP-BINDING PROTEIN; Part of the ABC transporter FtsEX involved in cellular division. (229 aa)
murB2PROBABLE UDP-N-ACETYLENOLPYRUVOYLGLUCOSAMINE REDUC; Cell wall formation. (368 aa)
murBUDP-N-ACETYLENOLPYRUVOYLGLUCOSAMINE REDUCTASE; Cell wall formation. (335 aa)
rodAPUTATIVE FTSW/RODA/SPOVE FAMILY CELL CYCLE PROTEIN; Belongs to the SEDS family. (441 aa)
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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