STRINGSTRING
metF metF metB metB Cgl2786 Cgl2786 aecD aecD metX metX metY metY Cgl0839 Cgl0839 metE metE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
metF5,10-Methylenetetrahydrofolate Reductase; Belongs to the methylenetetrahydrofolate reductase family. (326 aa)
metBCystathionine gamma-Synthase. (386 aa)
Cgl2786Putative L,L-Cystathionine gamma-Lyase. (382 aa)
aecDCystathionine beta-Lyase. (368 aa)
metXHomoserine O-Acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the AB hydrolase superfamily. MetX family. (377 aa)
metYO-Acetylhomoserine (Thiol)-Lyase; Catalyzes the conversion of O-acetyl-L-homoserine (OAH) into homocysteine in the methionine biosynthesis pathway (Ref.4,. Can also use dimethyldisulfide and methanethiol as reduced sulfur sources, leading to the direct formation of methionine. Has weak cystathionine gamma-synthase activity. (437 aa)
Cgl0839Alpha/beta hydrolase fold; Belongs to the AB hydrolase superfamily. MetX family. (349 aa)
metEHomocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (745 aa)
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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