node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
argB | argF | cg1582 | cg1584 | ACETYLGLUTAMATE KINASE; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | ORNITHINE CARBAMOYLTRANSFERASE; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | 0.998 |
argB | argJ | cg1582 | cg1581 | ACETYLGLUTAMATE KINASE; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | GLUTAMATE N-ACETYLTRANSFERASE; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.999 |
argB | metE | cg1582 | cg1290 | ACETYLGLUTAMATE KINASE; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.405 |
argB | trpCF | cg1582 | cg3362 | ACETYLGLUTAMATE KINASE; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | INDOLE-3-GGLYCEROL-PHOSPHATE SYNTHASE/PHOSPHORIBOSYLANTHRANILATE ISOMERASE; Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain (By similarity). | 0.481 |
argF | argB | cg1584 | cg1582 | ORNITHINE CARBAMOYLTRANSFERASE; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | ACETYLGLUTAMATE KINASE; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.998 |
argF | argJ | cg1584 | cg1581 | ORNITHINE CARBAMOYLTRANSFERASE; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | GLUTAMATE N-ACETYLTRANSFERASE; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.999 |
argJ | argB | cg1581 | cg1582 | GLUTAMATE N-ACETYLTRANSFERASE; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | ACETYLGLUTAMATE KINASE; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.999 |
argJ | argF | cg1581 | cg1584 | GLUTAMATE N-ACETYLTRANSFERASE; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | ORNITHINE CARBAMOYLTRANSFERASE; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | 0.999 |
argJ | trpCF | cg1581 | cg3362 | GLUTAMATE N-ACETYLTRANSFERASE; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | INDOLE-3-GGLYCEROL-PHOSPHATE SYNTHASE/PHOSPHORIBOSYLANTHRANILATE ISOMERASE; Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain (By similarity). | 0.516 |
folD | ribA | cg0750 | cg1798 | METHYLENETETRAHYDROFOLATE DEHYDROGENASE; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | PUTATIVE GTP CYCLOHYDROLASE II/3,4-DIHYDROXY-2-BUTANONE-4-PHOSPHATESYNTHASE; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | 0.566 |
folD | rmpA | cg0750 | cg3366 | METHYLENETETRAHYDROFOLATE DEHYDROGENASE; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Putative ribitol-specific enzyme II of PTS system. | 0.617 |
leuB | leuD | cg1453 | cg1488 | 3-ISOPROPYLMALATE DEHYDROGENASE; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity); Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | 3-ISOPROPYLMALATE DEHYDRATASE (SMALL SUBUNIT); Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.999 |
leuB | trpCF | cg1453 | cg3362 | 3-ISOPROPYLMALATE DEHYDROGENASE; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity); Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | INDOLE-3-GGLYCEROL-PHOSPHATE SYNTHASE/PHOSPHORIBOSYLANTHRANILATE ISOMERASE; Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain (By similarity). | 0.518 |
leuD | leuB | cg1488 | cg1453 | 3-ISOPROPYLMALATE DEHYDRATASE (SMALL SUBUNIT); Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 3-ISOPROPYLMALATE DEHYDROGENASE; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity); Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | 0.999 |
leuD | metE | cg1488 | cg1290 | 3-ISOPROPYLMALATE DEHYDRATASE (SMALL SUBUNIT); Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | Homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.589 |
leuD | trpCF | cg1488 | cg3362 | 3-ISOPROPYLMALATE DEHYDRATASE (SMALL SUBUNIT); Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | INDOLE-3-GGLYCEROL-PHOSPHATE SYNTHASE/PHOSPHORIBOSYLANTHRANILATE ISOMERASE; Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain (By similarity). | 0.632 |
metB | metE | cg2687 | cg1290 | Cystathionine gamma-Synthase. | Homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.982 |
metB | metX | cg2687 | cg0754 | Cystathionine gamma-Synthase. | Homoserine O-Acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the AB hydrolase superfamily. MetX family. | 0.982 |
metB | metY | cg2687 | cg0755 | Cystathionine gamma-Synthase. | O-Acetylhomoserine (Thiol)-Lyase; Catalyzes the conversion of O-acetyl-L-homoserine (OAH) into homocysteine in the methionine biosynthesis pathway (Ref.4,. Can also use dimethyldisulfide and methanethiol as reduced sulfur sources, leading to the direct formation of methionine. Has weak cystathionine gamma-synthase activity. | 0.948 |
metE | argB | cg1290 | cg1582 | Homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | ACETYLGLUTAMATE KINASE; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.405 |