node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aceA | gltB | cg2560 | cg0229 | ISOCITRATE LYASE; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | GLUTAMINE 2-OXOGLUTARATE AMINOTRANSFERASE LARGE SU. | 0.546 |
aceA | pgi | cg2560 | cg0973 | ISOCITRATE LYASE; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | GLUCOSE-6-PHOSPHATE ISOMERASE. | 0.463 |
aceA | ppc | cg2560 | cg1787 | ISOCITRATE LYASE; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | PHOSPHOENOLPYRUVATE CARBOXYLASE; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. | 0.767 |
aceA | sdhA | cg2560 | cg0446 | ISOCITRATE LYASE; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | Succinate dehydrogenase A. | 0.636 |
aceA | sdhB | cg2560 | cg0447 | ISOCITRATE LYASE; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | Succinate dehydrogenase B. | 0.655 |
aceA | sucC | cg2560 | cg2837 | ISOCITRATE LYASE; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | SUCCINYL-COA SYNTHETASE BETA SUBUNIT; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.692 |
aceA | sucD | cg2560 | cg2836 | ISOCITRATE LYASE; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | SUCCINYL-COA SYNTHETASE ALPHA SUBUNIT; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.478 |
gdh | glnA | cg2280 | cg2429 | NADP-SPECIFIC GLUTAMATE DEHYDROGENASE; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | GLUTAMINE SYNTHETASE I. | 0.959 |
gdh | gltB | cg2280 | cg0229 | NADP-SPECIFIC GLUTAMATE DEHYDROGENASE; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | GLUTAMINE 2-OXOGLUTARATE AMINOTRANSFERASE LARGE SU. | 0.999 |
gdh | gltD | cg2280 | cg0230 | NADP-SPECIFIC GLUTAMATE DEHYDROGENASE; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | GLUTAMINE 2-OXOGLUTARATE AMINOTRANSFERASE. | 0.939 |
gdh | gltS | cg2280 | cg1463 | NADP-SPECIFIC GLUTAMATE DEHYDROGENASE; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | PUTATIVE GLUTAMYL-TRNA SYNTHETASE; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.839 |
gdh | gltX | cg2280 | cg0289 | NADP-SPECIFIC GLUTAMATE DEHYDROGENASE; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | GLUTAMYL-TRNA SYNTHETASE-RELATED PROTEIN; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. | 0.835 |
gdh | pgi | cg2280 | cg0973 | NADP-SPECIFIC GLUTAMATE DEHYDROGENASE; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | GLUCOSE-6-PHOSPHATE ISOMERASE. | 0.740 |
glnA | gdh | cg2429 | cg2280 | GLUTAMINE SYNTHETASE I. | NADP-SPECIFIC GLUTAMATE DEHYDROGENASE; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | 0.959 |
glnA | gltB | cg2429 | cg0229 | GLUTAMINE SYNTHETASE I. | GLUTAMINE 2-OXOGLUTARATE AMINOTRANSFERASE LARGE SU. | 0.994 |
glnA | gltD | cg2429 | cg0230 | GLUTAMINE SYNTHETASE I. | GLUTAMINE 2-OXOGLUTARATE AMINOTRANSFERASE. | 0.981 |
glnA | gltS | cg2429 | cg1463 | GLUTAMINE SYNTHETASE I. | PUTATIVE GLUTAMYL-TRNA SYNTHETASE; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.834 |
glnA | gltX | cg2429 | cg0289 | GLUTAMINE SYNTHETASE I. | GLUTAMYL-TRNA SYNTHETASE-RELATED PROTEIN; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. | 0.818 |
gltB | aceA | cg0229 | cg2560 | GLUTAMINE 2-OXOGLUTARATE AMINOTRANSFERASE LARGE SU. | ISOCITRATE LYASE; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. | 0.546 |
gltB | gdh | cg0229 | cg2280 | GLUTAMINE 2-OXOGLUTARATE AMINOTRANSFERASE LARGE SU. | NADP-SPECIFIC GLUTAMATE DEHYDROGENASE; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | 0.999 |