STRINGSTRING
hom hom thrB thrB gatC gatC gatA gatA gatB gatB tpi tpi pgk pgk sdaA sdaA mqo mqo pyk pyk ilvA ilvA metF metF glnA glnA serB serB thrE thrE gltB gltB gltD gltD betB betB serC serC pgi pgi eno eno tdcB tdcB glyA glyA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
homHomoserine Dehydrogenase; Belongs to the homoserine dehydrogenase family. (445 aa)
thrBHomoserine Kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (309 aa)
gatCGLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT C); Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (99 aa)
gatAPROBABLE GLU-TRNA (GLN) AMIDOTRANSFERASE (SUBUNIT A); Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (497 aa)
gatBPROBABLE GLU-TRNAGLN AMIDOTRANSFERASE SUBUNIT B PR; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (501 aa)
tpiTRIOSEPHOSPHATE ISOMERASE; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (259 aa)
pgkPHOSPHOGLYCERATE KINASE; Belongs to the phosphoglycerate kinase family. (405 aa)
sdaAPROBABLE L-SERINE DEHYDRATASE (L-SERINE DEAMINASE); Belongs to the iron-sulfur dependent L-serine dehydratase family. (449 aa)
mqoMALATE:QUINONE OXIDOREDUCTASE OXIDOREDUCTASE. (500 aa)
pykPYRUVATE KINASE. (477 aa)
ilvATHREONINE DEHYDRATASE; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA (By similarity). (436 aa)
metF5,10-Methylenetetrahydrofolate Reductase; Belongs to the methylenetetrahydrofolate reductase family. (326 aa)
glnAGLUTAMINE SYNTHETASE I. (477 aa)
serBPhosphoserine Phosphatase. (446 aa)
thrETHREONINE EXPORT CARRIER. (489 aa)
gltBGLUTAMINE 2-OXOGLUTARATE AMINOTRANSFERASE LARGE SU. (1510 aa)
gltDGLUTAMINE 2-OXOGLUTARATE AMINOTRANSFERASE. (506 aa)
betBPUTATIVE BETAINE ALDEHYDE DEHYDROGENASE (BADH) OXIDOREDUCTASE. (497 aa)
serCPhosphoserine Transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (376 aa)
pgiGLUCOSE-6-PHOSPHATE ISOMERASE. (540 aa)
enoENOLASE (2-PHOSPHOGLYCERATE DEHYDRATASE; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (425 aa)
tdcBTHREONINE DEHYDRATASE. (310 aa)
glyASerine Hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (434 aa)
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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