node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARK03637.1 | ARK04908.1 | B8281_01700 | B8281_09355 | Anaerobic ribonucleoside-triphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.653 |
ARK03637.1 | ARK04909.1 | B8281_01700 | B8281_09360 | Anaerobic ribonucleoside-triphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Class 1b ribonucleoside-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.749 |
ARK03637.1 | ARK06555.1 | B8281_01700 | B8281_01705 | Anaerobic ribonucleoside-triphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.997 |
ARK03637.1 | ARK06812.1 | B8281_01700 | B8281_10875 | Anaerobic ribonucleoside-triphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxyguanosinetriphosphate triphosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the dGTPase family. Type 2 subfamily. | 0.900 |
ARK03637.1 | dcd | B8281_01700 | B8281_01335 | Anaerobic ribonucleoside-triphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | 0.968 |
ARK03637.1 | dut | B8281_01700 | B8281_13960 | Anaerobic ribonucleoside-triphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.974 |
ARK03637.1 | ndk | B8281_01700 | B8281_15115 | Anaerobic ribonucleoside-triphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.953 |
ARK04906.1 | ARK04908.1 | B8281_09345 | B8281_09355 | NrdH-redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.993 |
ARK04906.1 | ARK04909.1 | B8281_09345 | B8281_09360 | NrdH-redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | Class 1b ribonucleoside-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.973 |
ARK04906.1 | dcd | B8281_09345 | B8281_01335 | NrdH-redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | 0.490 |
ARK04906.1 | ndk | B8281_09345 | B8281_15115 | NrdH-redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.641 |
ARK04906.1 | nrdI | B8281_09345 | B8281_09350 | NrdH-redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | Class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI; Probably involved in ribonucleotide reductase function. | 0.989 |
ARK04906.1 | nrdR | B8281_09345 | B8281_14620 | NrdH-redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.454 |
ARK04908.1 | ARK03637.1 | B8281_09355 | B8281_01700 | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Anaerobic ribonucleoside-triphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.653 |
ARK04908.1 | ARK04906.1 | B8281_09355 | B8281_09345 | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | NrdH-redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.993 |
ARK04908.1 | ARK04909.1 | B8281_09355 | B8281_09360 | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Class 1b ribonucleoside-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.999 |
ARK04908.1 | dut | B8281_09355 | B8281_13960 | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.867 |
ARK04908.1 | ndk | B8281_09355 | B8281_15115 | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.974 |
ARK04908.1 | nrdI | B8281_09355 | B8281_09350 | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI; Probably involved in ribonucleotide reductase function. | 0.997 |
ARK04908.1 | nrdR | B8281_09355 | B8281_14620 | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.651 |