STRINGSTRING
slyA slyA leuO leuO topA topA araC araC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
slyATranscriptional regulator; Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family. (146 aa)
leuOProbable transcriptional activator for leuABCD operon; Code: K; COG: COG0583; Belongs to the LysR transcriptional regulatory family. (373 aa)
topADNA topoisomerase type I, omega protein; Code: L; COG: COG0550. (865 aa)
araCTranscriptional regulator for ara operon; Code: K; COG: COG2207. (292 aa)
Your Current Organism:
Shigella flexneri
NCBI taxonomy Id: 198214
Other names: S. flexneri 2a str. 301, Shigella flexneri 2a str. 301, Shigella flexneri serotype 2a str. 301
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.