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| | ilvG | Acetolactate synthase large subunit; Protein involved in magnesium ion binding, transferase activity, thiamin pyrophosphate binding, acetolactate synthase activity, FAD binding, catalytic activity and branched chain family amino acid biosynthetic process. (548 aa) |
| | ilvM | Acetolactate synthase II, small subunit. (85 aa) |
| | ilvE | Branched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (308 aa) |
| | ilvD | Dihydroxyacid dehydratase; Protein involved in catalytic activity, dihydroxy-acid dehydratase activity, metabolic process and branched chain family amino acid biosynthetic process; Belongs to the IlvD/Edd family. (616 aa) |
| | ilvA | Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (514 aa) |
| | ilvC | Ketol-acid reductoisomerase, NAD(P)-binding protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (492 aa) |
| | putP | Proline:sodium symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (499 aa) |
| | putA | Proline dehydrogenase (Proline oxidase) / Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1329 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (274 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase, NAD(P)-binding protein; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (364 aa) |
| | pck | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (539 aa) |
| | thrC | Threonine synthase; Protein involved in catalytic activity, threonine synthase activity, threonine biosynthetic process, metabolic process and amino acid metabolic process. (429 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (309 aa) |
| | thrA | Bifunctional aspartokinase I/homoserine dehydrogenase I; Protein involved in aspartate kinase activity, homoserine dehydrogenase activity, amino acid binding, threonine biosynthetic process, homoserine biosynthetic process, amino acid biosynthetic process, aspartate family amino acid biosynthetic process and metabolic process. (818 aa) |
| | serA | D-3-phosphoglycerate dehydrogenase; Protein involved in oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, NAD binding, cofactor binding, amino acid binding, L-serine biosynthetic process and metabolic process; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (410 aa) |
| | mqo | Malate:quinone oxidoreductase; Protein involved in (DEPRECATED) molecular function unknown, tricarboxylic acid cycle and (DEPRECATED) biological process unknown. (523 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (361 aa) |
| | ADN00322.1 | Oxalate decarboxylase oxdD; Protein involved in nutrient reservoir activity and xenobiotic metabolic process. (416 aa) |
| | argD | Ornithine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (407 aa) |
| | pabA | Aminodeoxychorismate synthase, subunit II; Protein involved in anthranilate synthase activity, catalytic activity, ligase activity, folic acid biosynthetic process, metabolic process, biosynthetic process and glutamine metabolic process. (191 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (269 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (396 aa) |
| | trpC | Protein involved in catalytic activity, indole-3-glycerol-phosphate synthase activity, phosphoribosylanthranilate isomerase activity, tryptophan biosynthetic process, metabolic process and tryptophan metabolic process; Belongs to the TrpC family. (461 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (338 aa) |
| | trpG | Anthranilate synthase component II; Protein involved in catalytic activity, ligase activity, anthranilate synthase activity, tryptophan biosynthetic process, biosynthetic process, glutamine metabolic process and metabolic process. (192 aa) |
| | trpE | Protein involved in anthranilate synthase activity, oxo-acid-lyase activity, tryptophan biosynthetic process and biosynthetic process. (520 aa) |
| | ADM98708.1 | Branched-chain amino acid aminotransferase; Protein involved in catalytic activity, transcription factor activity, sequence-specific DNA binding, metabolic process and regulation of transcription, DNA-dependent. (305 aa) |
| | aatA | Aspartate aminotransferase; Protein involved in 1-aminocyclopropane-1-carboxylate synthase activity, transferase activity, transferring nitrogenous groups, pyridoxal phosphate binding, catalytic activity, amino acid catabolic process, aspartate biosynthetic process and biosynthetic process. (400 aa) |
| | gltD | Glutamate synthase, 4Fe-4S protein, small subunit; Protein involved in oxidoreductase activity, FAD binding, oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor, iron-sulfur cluster binding, glutamate biosynthetic process, nitrogen compound metabolic process and (OBSOLETE) electron transport. (472 aa) |
| | gltB | Glutamate synthase, large subunit; Protein involved in glutamate synthase activity, oxidoreductase activity, catalytic activity, glutamate biosynthetic process, nitrogen compound metabolic process and metabolic process. (1486 aa) |
| | ADM96560.1 | Protein involved in shikimate 5-dehydrogenase activity and amino acid biosynthetic process. (269 aa) |
| | ADM97759.1 | Probable aspartate racemase; Protein involved in racemase and epimerase activity, acting on amino acids and derivatives, peptidoglycan biosynthetic process, response to drug, metabolic process and amino acid metabolic process; Belongs to the aspartate/glutamate racemases family. (238 aa) |
| | ADM97696.1 | EBNA-1 nuclear protein; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. (330 aa) |
| | ADM97695.1 | Mandelate racemase/muconate lactonizing enzyme family protein; Protein involved in catalytic activity, xenobiotic metabolic process and metabolic process. (336 aa) |
| | ADM97694.1 | D-alanine aminotransferase; Protein involved in catalytic activity, amino acid biosynthetic process and metabolic process. (286 aa) |
| | argA | N-acetylglutamate synthase; Protein involved in amino-acid N-acetyltransferase activity, N-acetyltransferase activity, arginine biosynthetic process, amino acid biosynthetic process and metabolic process; Belongs to the acetyltransferase family. ArgA subfamily. (441 aa) |
| | ADM97260.1 | D-3-phosphoglycerate dehydrogenase; Protein involved in oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, NAD binding, cofactor binding, L-serine biosynthetic process and metabolic process; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (348 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Protein involved in acyltransferase activity, transferase activity, transferring glycosyl groups and lysine biosynthetic process via diaminopimelate; Belongs to the transferase hexapeptide repeat family. (274 aa) |
| | proB | Gamma-glutamate kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (367 aa) |
| | proA | Gamma-glutamylphosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (417 aa) |
| | ADM99715.1 | Poly(glycerophosphate chain) D-alanine transfer protein DltD; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. (379 aa) |
| | argG | Protein involved in argininosuccinate synthase activity, ATP binding and arginine biosynthetic process; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (449 aa) |
| | avtA | Valine-pyruvate aminotransferase; Protein involved in catalytic activity, pyridoxal phosphate binding, transferase activity, transferring nitrogenous groups, amino acid metabolic process, alanine biosynthetic process and biosynthetic process. (418 aa) |
| | ADN00687.1 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (393 aa) |
| | ADN00717.1 | Protein involved in 4-hydroxyphenylpyruvate dioxygenase activity, amino acid catabolic process and aromatic amino acid family metabolic process. (388 aa) |
| | ADN00733.1 | Pyridine nucleotide-disulfide oxidoreductase family protein; Protein involved in oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor, oxidoreductase activity, iron-sulfur cluster binding, electron carrier activity, FAD binding, metabolic process, glutamate biosynthetic process and (OBSOLETE) electron transport. (664 aa) |
| | glnA | Glutamine synthetase; Protein involved in glutamate-ammonia ligase activity, catalytic activity, glutamine biosynthetic process, nitrogen compound metabolic process and nitrogen fixation. (469 aa) |
| | ADM96950.1 | Protein involved in electron carrier activity, oxidoreductase activity, iron-sulfur cluster binding, catalytic activity, thiamin pyrophosphate binding, iron ion binding, oxidoreductase activity, acting on the aldehyde or oxo group of donors, tricarboxylic acid cycle, fermentation and (OBSOLETE) electron transport. (1177 aa) |
| | ddlA | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (366 aa) |
| | argI | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (338 aa) |
| | leuC | 3-isopropylmalate isomerase subunit, dehydratase component; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (466 aa) |
| | leuD | 3-isopropylmalate isomerase subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (200 aa) |
| | ilvB | Acetolactate synthase large subunit; Protein involved in magnesium ion binding, transferase activity, thiamin pyrophosphate binding, acetolactate synthase activity, FAD binding, catalytic activity and branched chain family amino acid biosynthetic process. (554 aa) |
| | ilvN | Protein involved in acetolactate synthase activity, amino acid binding, branched chain family amino acid biosynthetic process and metabolic process. (97 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (273 aa) |
| | maeB | Protein involved in malic enzyme activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, NAD binding, acyltransferase activity, metal ion binding, malate metabolic process and metabolic process. (759 aa) |
| | fumA | Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (547 aa) |
| | yeaU | Protein involved in tartrate dehydrogenase activity, NAD binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, fermentation and metabolic process. (361 aa) |
| | aroE | Dehydroshikimate reductase, NAD(P)-binding protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (273 aa) |
| | gltA | Citrate synthase; Protein involved in transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer, tricarboxylic acid cycle, aerobic respiration and anaerobic respiration; Belongs to the citrate synthase family. (428 aa) |
| | tyrA | Protein involved in chorismate mutase activity, prephenate dehydrogenase activity, tyrosine biosynthetic process, L-phenylalanine biosynthetic process and aromatic amino acid family biosynthetic process. (373 aa) |
| | pheA | Protein involved in chorismate mutase activity, prephenate dehydratase activity, L-phenylalanine biosynthetic process, tyrosine biosynthetic process and aromatic amino acid family biosynthetic process. (393 aa) |
| | fdoG | Formate dehydrogenase-O, large subunit; This gene does not encode a selenopolypeptide -- aa position 196 is C (Cys), not U (SeCys); Protein involved in (DEPRECATED) electron donor activity, oxidoreductase activity, molybdenum ion binding, formate dehydrogenase activity, anaerobic respiration, (OBSOLETE) electron transport and cellular respiration. (1016 aa) |
| | fdoH | Formate dehydrogenase-O, Fe-S subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (300 aa) |
| | fdoI | Formate dehydrogenase-O, cytochrome b556 subunit; Protein involved in (DEPRECATED) electron donor activity, formate dehydrogenase activity, anaerobic respiration, cytochrome complex assembly, (OBSOLETE) electron transport and cellular respiration. (211 aa) |
| | ADM97331.1 | Phosphoserine phosphatase; Protein involved in (DEPRECATED) molecular function unknown, phosphatase activity, catalytic activity, (DEPRECATED) biological process unknown and metabolic process. (218 aa) |
| | asnA | L-asparaginase; Protein involved in sugar:hydrogen symporter activity, asparaginase activity, nitrogen compound metabolic process, amino acid catabolic process, amino acid metabolic process, phosphoenolpyruvate-dependent sugar phosphotransferase system and asparagine metabolic process; Belongs to the asparaginase 1 family. (348 aa) |
| | aroL | Shikimate kinase II; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate. (173 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (879 aa) |
| | argE | Acetylornithine deacetylase; Protein involved in metallopeptidase activity, hydrolase activity, protein dimerization activity, zinc ion binding, acetylornithine deacetylase activity, cobalt ion binding, arginine biosynthetic process and proteolysis. (383 aa) |
| | argC | N-acetyl-gamma-glutamylphosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (334 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate. (257 aa) |
| | usg | Protein involved in aspartate-semialdehyde dehydrogenase activity, NADP binding, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, NAD binding, protein dimerization activity, amino acid biosynthetic process and amino acid metabolic process. (336 aa) |
| | pdxB | Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate. (377 aa) |
| | lysC | Aspartokinase III; Protein involved in aspartate kinase activity, amino acid binding, lysine biosynthetic process via diaminopimelate, homoserine biosynthetic process, biosynthetic process, amino acid biosynthetic process and metabolic process; Belongs to the aspartokinase family. (454 aa) |
| | nifJ | Protein involved in iron ion binding, oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxidoreductase activity, electron carrier activity, iron-sulfur cluster binding, catalytic activity, thiamin pyrophosphate binding, fermentation and (OBSOLETE) electron transport. (1165 aa) |
| | pabC | 4-amino-4-deoxychorismate lyase component of para-aminobenzoate synthase multienzyme complex; Protein involved in catalytic activity, folic acid biosynthetic process and metabolic process. (267 aa) |
| | ADM98984.1 | Hypothetical oxidoreductase; Protein involved in (DEPRECATED) molecular function unknown, oxidoreductase activity, (DEPRECATED) biological process unknown and metabolic process; Belongs to the LDH2/MDH2 oxidoreductase family. (353 aa) |
| | budB | Acetolactate synthase, catabolic; Protein involved in magnesium ion binding, transferase activity, thiamin pyrophosphate binding, acetolactate synthase activity, FAD binding, catalytic activity and branched chain family amino acid biosynthetic process; Belongs to the TPP enzyme family. (565 aa) |
| | budA | Alpha-acetolactate decarboxylase; Protein involved in carbohydrate catabolic process; Belongs to the alpha-acetolactate decarboxylase family. (262 aa) |
| | dat | D-alanine aminotransferase; Protein involved in catalytic activity, amino acid biosynthetic process and metabolic process. (342 aa) |
| | ilvH | Acetolactate synthase III, thiamin-dependent, small subunit; Protein involved in acetolactate synthase activity, amino acid binding, branched chain family amino acid biosynthetic process and metabolic process. (163 aa) |
| | ilvI | Acetolactate synthase large subunit; Protein involved in magnesium ion binding, transferase activity, thiamin pyrophosphate binding, acetolactate synthase activity, FAD binding, catalytic activity and branched chain family amino acid biosynthetic process. (573 aa) |
| | acs | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (653 aa) |
| | dapE | N-succinyl-L,L-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (375 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa) |
| | lysA | Diaminopimelate decarboxylase, PLP-binding protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (420 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (273 aa) |
| | ADM97791.1 | Probable aspartate racemase; Glutamate racemase is required for the biosynthesis of peptidoglycan and some peptide-based antibiotics; Protein involved in racemase and epimerase activity, acting on amino acids and derivatives, response to drug, peptidoglycan biosynthetic process, metabolic process and amino acid metabolic process. (256 aa) |
| | dcyD | D-cysteine desulfhydrase, PLP-dependent; Protein involved in catalytic activity, amino acid catabolic process, sulfur metabolic process and metabolic process. (337 aa) |
| | ADM97789.1 | Malate/lactate dehydrogenase; Protein involved in oxidoreductase activity, tricarboxylic acid cycle and metabolic process; Belongs to the LDH2/MDH2 oxidoreductase family. (340 aa) |
| | aspA | Protein involved in aspartate ammonia-lyase activity, catalytic activity, amino acid metabolic process, asparagine biosynthetic process, lysine biosynthetic process via diaminopimelate and aspartate metabolic process. (479 aa) |
| | yhhY | Putative acetyltransferase; Protein involved in (DEPRECATED) molecular function unknown, N-acetyltransferase activity, (DEPRECATED) biological process unknown and metabolic process. (168 aa) |
| | dadA | D-amino acid dehydrogenase; Oxidative deamination of D-amino acids. (416 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. (299 aa) |
| | hisD | Bifunctional histidinal dehydrogenase/histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (436 aa) |
| | hisC | Histidinol-phosphate aminotransferase; Protein involved in transferase activity, transferring nitrogenous groups, pyridoxal phosphate binding, histidinol-phosphate transaminase activity, transferase activity, catalytic activity, histidine biosynthetic process, biosynthetic process and metabolic process; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (356 aa) |
| | hisB | Bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase; Protein involved in imidazoleglycerol-phosphate dehydratase activity, histidinol-phosphatase activity and histidine biosynthetic process. (355 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit with HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (196 aa) |
| | hisA | N-(5'-phospho-L-ribosyl-formimino)-5-amino-1- (5'-phosphoribosyl)-4-imidazolecarboxamide isomerase; Protein involved in catalytic activity, histidine biosynthetic process and metabolic process. (245 aa) |
| | hisF | Imidazole glycerol phosphate synthase, catalytic subunit with HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (258 aa) |
| | hisI | Histidine biosynthesis bifunctional protein HisIE; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown; In the N-terminal section; belongs to the PRA-CH family. (204 aa) |
| | ldhA | Fermentative D-lactate dehydrogenase, NAD-dependent; Protein involved in oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, NAD binding, cofactor binding, fermentation, lactate oxidation and metabolic process; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (330 aa) |
| | ADM99702.1 | Acetylornithine deacetylase; Protein involved in metallopeptidase activity, hydrolase activity, protein dimerization activity and proteolysis. (426 aa) |
| | ADM99707.1 | Acetylornithine deacetylase; Protein involved in peroxidase activity, metallopeptidase activity, hydrolase activity, protein dimerization activity, response to oxidative stress and proteolysis. (409 aa) |
| | ADM99712.1 | D-alanine carrier protein DltC; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. (73 aa) |
| | ADM99713.1 | D-alanine-activating enzyme (DAE) (D-alanine-D-alanyl carrier protein ligase) (DCL); Protein involved in catalytic activity, AMP binding, metabolic process and teichoic acid biosynthetic process. (477 aa) |
| | ADM99714.1 | D-alanyl transfer protein DltB; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown; Belongs to the membrane-bound acyltransferase family. (372 aa) |
| | virA | Protein involved in catalytic activity, diaminopimelate decarboxylase activity and lysine biosynthetic process via diaminopimelate. (440 aa) |
| | iaaA | L-asparaginase; Protein involved in asparaginase activity, aspartate biosynthetic process, alanine biosynthetic process, nitrogen compound metabolic process and glycoprotein catabolic process. (319 aa) |
| | alr | Alanine racemase 1, PLP-binding, biosynthetic; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (358 aa) |
| | ADM99934.1 | Arogenate dehydratase; Protein involved in transporter activity, L-phenylalanine biosynthetic process and transport. (288 aa) |
| | tyrB | Tyrosine aminotransferase, tyrosine-repressible, PLP-dependent; Protein involved in catalytic activity, transaminase activity, transferase activity, transferring nitrogenous groups, pyridoxal phosphate binding, tyrosine biosynthetic process, L-phenylalanine biosynthetic process, leucine biosynthetic process, biosynthetic process and amino acid metabolic process. (397 aa) |
| | mdh | Malate dehydrogenase, NAD(P)-binding protein; Catalyzes the reversible oxidation of malate to oxaloacetate. (313 aa) |
| | argR | DNA-binding transcriptional regulatory protein; Regulates arginine biosynthesis genes. (156 aa) |
| | leuA-2 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (567 aa) |
| | aspC | Protein involved in transaminase activity, catalytic activity, transferase activity, transferring nitrogenous groups, pyridoxal phosphate binding, aspartate biosynthetic process, amino acid catabolic process, amino acid metabolic process and biosynthetic process. (396 aa) |
| | pabB | Aminodeoxychorismate synthase, subunit I; Protein involved in oxo-acid-lyase activity, folic acid biosynthetic process, biosynthetic process and folic acid and derivative biosynthetic process. (487 aa) |
| | sfcA | Malate dehydrogenase, (decarboxylating, NAD-requiring) (malic enzyme); Protein involved in malic enzyme activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, NAD binding, gluconeogenesis and malate metabolic process. (565 aa) |
| | metL | Bifunctional aspartokinase/homoserine dehydrogenase; Protein involved in aspartate kinase activity, homoserine dehydrogenase activity, methionine biosynthetic process, homoserine biosynthetic process, amino acid biosynthetic process and aspartate family amino acid biosynthetic process. (811 aa) |
| | yfbQ | Predicted aminotransferase; Protein involved in catalytic activity, pyridoxal phosphate binding, transferase activity, transferring nitrogenous groups, 1-aminocyclopropane-1-carboxylate synthase activity and biosynthetic process. (404 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (164 aa) |
| | purU | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (283 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (435 aa) |
| | fumC | Fumarate hydratase (fumarase C),aerobic Class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa) |
| | aroK | Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (361 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (524 aa) |
| | gltP-2 | Protein involved in sodium:dicarboxylate symporter activity and dicarboxylic acid transport; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (429 aa) |
| | serC | 3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (361 aa) |
| | ansA | Cytoplasmic L-asparaginase I; Protein involved in asparaginase activity, amino acid catabolic process and amino acid metabolic process. (339 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (363 aa) |
| | Dda3937_04568 | Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; Putative transcriptional regulator pseudogene containing internal frameshift, split into two open reading frames; Protein involved in (OBSOLETE) ATP-binding cassette (ABC) transporter activity. (270 aa) |
| | pykF | Pyruvate kinase I; Protein involved in magnesium ion binding, pyruvate kinase activity, potassium ion binding and glycolysis; Belongs to the pyruvate kinase family. (470 aa) |
| | argH | Argininosuccinate lyase; Protein involved in catalytic activity, argininosuccinate lyase activity, arginine biosynthetic process and arginine biosynthetic process via ornithine. (457 aa) |
