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| | add | Protein involved in deaminase activity, adenosine deaminase activity, nucleobase, nucleoside and nucleotide interconversion and purine ribonucleoside monophosphate biosynthetic process; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (338 aa) |
| | grxA | Glutaredoxin 1, redox coenzyme for ribonucleotide reductase (RNR1a); Protein involved in electron carrier activity, protein disulfide oxidoreductase activity, cell redox homeostasis and (OBSOLETE) electron transport. (85 aa) |
| | folE | Protein involved in GTP cyclohydrolase I activity, folic acid biosynthetic process and aromatic compound biosynthetic process. (222 aa) |
| | pncB | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (401 aa) |
| | pyrD | Dihydro-orotate oxidase, FMN-linked; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (335 aa) |
| | pyrC | Dihydro-orotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (347 aa) |
| | htrB | Lipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). (306 aa) |
| | purT | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (392 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (491 aa) |
| | pykA | Pyruvate kinase II; Protein involved in magnesium ion binding, pyruvate kinase activity, potassium ion binding, glycolysis, fermentation and anaerobic respiration; Belongs to the pyruvate kinase family. (480 aa) |
| | ADM98177.1 | Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; Protein involved in (DEPRECATED) molecular function unknown, acyltransferase activity, (DEPRECATED) biological process unknown and metabolic process. (248 aa) |
| | ygbA | Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. (136 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (143 aa) |
| | ispG | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (373 aa) |
| | yeaB | Predicted NUDIX hydrolase; Protein involved in (DEPRECATED) molecular function unknown, hydrolase activity and (DEPRECATED) biological process unknown; Belongs to the Nudix hydrolase family. PCD1 subfamily. (207 aa) |
| | ADM97995.1 | Cytosolic long-chain acyl-CoA thioester hydrolase family protein; Protein involved in (DEPRECATED) molecular function unknown, catalytic activity and (DEPRECATED) biological process unknown. (131 aa) |
| | moeB | Molybdopterin synthase sulfurylase; Protein involved in catalytic activity and Mo-molybdopterin cofactor biosynthetic process. (251 aa) |
| | moeA | Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (448 aa) |
| | moaA | Molybdopterin biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (329 aa) |
| | moaB | Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (170 aa) |
| | moaC | Molybdopterin biosynthesis, protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (160 aa) |
| | moaD | Molybdopterin synthase, small subunit; Protein involved in Mo-molybdopterin cofactor biosynthetic process and sulfur metabolic process. (81 aa) |
| | moaE | Molybdopterin synthase, large subunit; Protein involved in Mo-molybdopterin cofactor biosynthetic process. (149 aa) |
| | ADM98771.1 | Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. (451 aa) |
| | yeiU | Undecaprenyl pyrophosphate phosphatase; Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P); Belongs to the LpxT phosphotransferase family. (247 aa) |
| | nadB | Quinolinate synthase, L-aspartate oxidase (B protein) subunit; Catalyzes the oxidation of L-aspartate to iminoaspartate. (533 aa) |
| | pfkA | 6-phosphofructokinase I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (256 aa) |
| | glpK | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (503 aa) |
| | ADM96417.1 | Peroxiredoxin family protein/glutaredoxin; Protein involved in electron carrier activity, oxidoreductase activity, protein disulfide oxidoreductase activity, (OBSOLETE) electron transport and cell redox homeostasis. (243 aa) |
| | ispD | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. (242 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (165 aa) |
| | dcd | 2'-deoxycytidine 5'-triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (193 aa) |
| | udk | Protein involved in uridine kinase activity, ATP binding, kinase activity, nucleobase, nucleoside and nucleotide interconversion and biosynthetic process. (213 aa) |
| | ybhE | 6-phosphogluconolactonase; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate. (331 aa) |
| | pgsA | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (182 aa) |
| | nrdF | Ribonucleoside-diphosphate reductase 2, beta subunit, ferritin-like protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (330 aa) |
| | nadA | Quinolinate synthase, subunit A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. (348 aa) |
| | gpmA | Phosphoglyceromutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (250 aa) |
| | ybhA | Pyridoxal phosphatase / fructose 1,6-bisphosphatase; Protein involved in (DEPRECATED) molecular function unknown, hydrolase activity, catalytic activity, (DEPRECATED) biological process unknown and metabolic process. (273 aa) |
| | ybhO | Cardiolipin synthetase; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (401 aa) |
| | yfcD | Predicted NUDIX hydrolase; Protein involved in (DEPRECATED) molecular function unknown, isopentenyl-diphosphate delta-isomerase activity, hydrolase activity, (DEPRECATED) biological process unknown and isoprenoid biosynthetic process. (203 aa) |
| | pta | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (713 aa) |
| | ackA | Acetate kinase A and propionate kinase 2; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa) |
| | yfbR | Nucleotidase; Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates. (199 aa) |
| | pgpB | Protein involved in phospholipid biosynthetic process. (256 aa) |
| | pyrF | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (244 aa) |
| | purU | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (283 aa) |
| | tdk | Protein involved in thymidine kinase activity, ATP binding and nucleobase, nucleoside and nucleotide interconversion. (199 aa) |
| | cmk | Protein involved in cytidylate kinase activity, ATP binding, nucleotide kinase activity, nucleobase, nucleoside and nucleotide interconversion and nucleobase, nucleoside, nucleotide and nucleic acid metabolic process. (228 aa) |
| | hpt | Protein involved in transferase activity, hypoxanthine phosphoribosyltransferase activity, nucleobase, nucleoside and nucleotide interconversion, nucleoside metabolic process and purine ribonucleoside salvage; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (177 aa) |
| | phnG | Protein involved in phosphorus metabolic process, phosphonate transport and phosphonate metabolic process. (149 aa) |
| | phnH | Protein involved in phosphorus metabolic process and phosphonate transport. (191 aa) |
| | phnI | Protein involved in phosphorus metabolic process and phosphonate transport. (363 aa) |
| | phnJ | PhnJ protein; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. Belongs to the PhnJ family. (284 aa) |
| | phnK | Protein involved in (OBSOLETE) ATP-binding cassette (ABC) transporter activity, ATP binding, ATPase activity, nucleotide binding, nucleoside-triphosphatase activity and phosphorus metabolic process. (270 aa) |
| | phnL | Protein involved in (OBSOLETE) ATP-binding cassette (ABC) transporter activity, ATP binding, ATPase activity, nucleotide binding, nucleoside-triphosphatase activity and phosphorus metabolic process. (240 aa) |
| | phnM | Metal-dependent hydrolase involved in phosphonate metabolism; Protein involved in phosphorus metabolic process. (389 aa) |
| | phnN | ATP-binding protein phnN; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). (195 aa) |
| | phnP | Metal-dependent hydrolases of the beta-lactamase superfamily I; Protein involved in hydrolase activity and phosphorus metabolic process. (249 aa) |
| | nrdB | Ribonucleotide reductase of class Ia (aerobic), beta subunit; Protein involved in ribonucleoside-diphosphate reductase activity, oxidoreductase activity, transition metal ion binding, nucleobase, nucleoside and nucleotide interconversion and deoxyribonucleoside diphosphate metabolic process. (376 aa) |
| | rpe | D-ribulose-5-phosphate 3-epimerase; Protein involved in catalytic activity, ribulose-phosphate 3-epimerase activity, pentose-phosphate shunt, oxidative branch, carbohydrate catabolic process, pentose-phosphate shunt, non-oxidative branch, metabolic process and carbohydrate metabolic process. (225 aa) |
| | yceF | Predicted protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily. (200 aa) |
| | plsX | Fatty acid/phospholipid synthesis protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (348 aa) |
| | coaA | Pantothenate kinase; Protein involved in ATP binding, kinase activity, pantothenate kinase activity, coenzyme A biosynthetic process and biosynthetic process. (316 aa) |
| | nudF | ADP-ribose pyrophosphatase; Protein involved in hydrolase activity, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, metal ion binding and gluconeogenesis; Belongs to the Nudix hydrolase family. (211 aa) |
| | cdsA | CDP-diglyceride synthase; Protein involved in phosphatidate cytidylyltransferase activity and phospholipid biosynthetic process; Belongs to the CDS family. (284 aa) |
| | ADM96466.1 | Molybdopterin-guanine dinucleotide biosynthesis protein B; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. (78 aa) |
| | ushA | Protein involved in hydrolase activity, hydrolase activity, acting on ester bonds, nucleotide-sugar biosynthetic process and nucleotide catabolic process; Belongs to the 5'-nucleotidase family. (550 aa) |
| | gnd | Gluconate-6-phosphate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (468 aa) |
| | citD_2 | Citrate lyase, acyl carrier (gamma) subunit; Covalent carrier of the coenzyme of citrate lyase. (96 aa) |
| | citE_2 | Citrate lyase, citryl-ACP lyase (beta) subunit; Protein involved in carbon-carbon lyase activity, citryl-CoA lyase activity, cellular aromatic compound metabolic process and acetyl-CoA metabolic process; Belongs to the HpcH/HpaI aldolase family. (297 aa) |
| | citF_2 | Citrate lyase, citrate-ACP transferase (alpha) subunit; Protein involved in citrate CoA-transferase activity and acetyl-CoA metabolic process. (509 aa) |
| | citD_1 | Citrate lyase, acyl carrier (gamma) subunit. (96 aa) |
| | citE_1 | Citrate lyase, citryl-ACP lyase (beta) subunit; Protein involved in carbon-carbon lyase activity, citryl-CoA lyase activity, cellular aromatic compound metabolic process and acetyl-CoA metabolic process; Belongs to the HpcH/HpaI aldolase family. (297 aa) |
| | lpxM | Acyl (myristate) transferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A. (334 aa) |
| | pncA | Nicotinamidase/pyrazinamidase; Protein involved in catalytic activity and metabolic process. (213 aa) |
| | pykF | Pyruvate kinase I; Protein involved in magnesium ion binding, pyruvate kinase activity, potassium ion binding and glycolysis; Belongs to the pyruvate kinase family. (470 aa) |
| | tktA | Transketolase 1, thiamin-binding protein; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (664 aa) |
| | yqgE | Predicted protein; Homologous to P. aeruginosa AlgH regulatory protein; Protein involved in transcription and regulation of transcription, DNA-dependent; Belongs to the UPF0301 (AlgH) family. (187 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (432 aa) |
| | yjeF | Predicted carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] (513 aa) |
| | citF_1 | Citrate lyase alpha chain; Protein involved in citrate CoA-transferase activity, tricarboxylic acid cycle and acetyl-CoA metabolic process. (509 aa) |
| | avrM | Avirulence protein; Putative type III (hrp) secreted protein; probably effector; Protein involved in (DEPRECATED) molecular function unknown, metallopeptidase activity, zinc ion binding, (DEPRECATED) biological process unknown and proteolysis. (630 aa) |
| | dgt | Deoxyguanosine triphosphate triphosphohydrolase; dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs; Belongs to the dGTPase family. Type 1 subfamily. (505 aa) |
| | yjdB | Putative membrane protein; Protein involved in (DEPRECATED) molecular function unknown, sulfuric ester hydrolase activity, ATP binding, ATPase activity, (DEPRECATED) biological process unknown and metabolic process. (547 aa) |
| | cls | Cardiolipin synthase 1; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (486 aa) |
| | yciA | Esterase; Protein involved in (DEPRECATED) molecular function unknown, catalytic activity and (DEPRECATED) biological process unknown. (140 aa) |
| | guaB | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (487 aa) |
| | guaA | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. (525 aa) |
| | ADM98316.1 | Nudix hydrolase family protein YffH; Protein involved in (DEPRECATED) molecular function unknown, hydrolase activity, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, metal ion binding and (DEPRECATED) biological process unknown. (207 aa) |
| | prsA | Phosphoribosylpyrophosphate synthase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (315 aa) |
| | ispE | 4-diphosphocytidyl-2-C-methylerythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. (290 aa) |
| | pdxY | Pyridoxal kinase 2/pyridoxine kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. (308 aa) |
| | ADN00755.1 | Nikkomycin biosynthesis protein, carboxylase; Protein involved in (DEPRECATED) molecular function unknown, catalytic activity, ATP binding, (DEPRECATED) biological process unknown and (OBSOLETE) electron transport. (402 aa) |
| | glmU | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (456 aa) |
| | atpC | F1 sector of membrane-bound ATP synthase, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (140 aa) |
| | atpD | F1 sector of membrane-bound ATP synthase, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (460 aa) |
| | atpG | F1 sector of membrane-bound ATP synthase, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (287 aa) |
| | atpA | F1 sector of membrane-bound ATP synthase, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (513 aa) |
| | atpH | F1 sector of membrane-bound ATP synthase, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (177 aa) |
| | atpF | F0 sector of membrane-bound ATP synthase, subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (156 aa) |
| | atpE | F0 sector of membrane-bound ATP synthase, subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (79 aa) |
| | atpB | F0 sector of membrane-bound ATP synthase, subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (263 aa) |
| | cpdB | Protein involved in hydrolase activity, 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity, hydrolase activity, acting on ester bonds, nucleobase, nucleoside and nucleotide interconversion, nucleotide catabolic process and nucleotide metabolic process; Belongs to the 5'-nucleotidase family. (671 aa) |
| | cysQ | PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (246 aa) |
| | ygiH | Conserved inner membrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (213 aa) |
| | relA | GTP pyrophosphokinase / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (745 aa) |
| | mazG | Nucleoside triphosphate pyrophosphohydrolase; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. (267 aa) |
| | pyrG | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (432 aa) |
| | thiG | Thiamin biosynthesis ThiGH complex subunit; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (259 aa) |
| | thiS | Thiamin biosynthesis protein, sulfur donor; Protein involved in thiamin biosynthetic process and sulfur metabolic process. (66 aa) |
| | thiF | Thiamin (thiazole moiety) biosynthesis protein; Protein involved in catalytic activity and thiamin biosynthetic process. (249 aa) |
| | thiE | Thiamin phosphate synthase (thiamin phosphate pyrophosphorylase); Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (211 aa) |
| | thiC | Thiamin (pyrimidine moiety) biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (655 aa) |
| | nudC | NADH pyrophosphatase; Protein involved in (DEPRECATED) molecular function unknown, hydrolase activity and (DEPRECATED) biological process unknown; Belongs to the Nudix hydrolase family. NudC subfamily. (257 aa) |
| | purD | Protein involved in catalytic activity, ATP binding, phosphoribosylamine-glycine ligase activity, purine nucleotide biosynthetic process and purine base biosynthetic process; Belongs to the GARS family. (429 aa) |
| | purH | Protein involved in IMP cyclohydrolase activity, phosphoribosylaminoimidazolecarboxamide formyltransferase activity, purine nucleotide biosynthetic process and nucleobase, nucleoside and nucleotide interconversion. (529 aa) |
| | gppA | Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. (498 aa) |
| | ADN00444.1 | Adenylosuccinate lyase; Protein involved in catalytic activity, adenylosuccinate lyase activity, metabolic process and purine ribonucleotide biosynthetic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (454 aa) |
| | cyaA | Protein involved in adenylate cyclase activity, nucleobase, nucleoside and nucleotide interconversion and cAMP biosynthetic process; Belongs to the adenylyl cyclase class-1 family. (852 aa) |
| | glpA | Sn-glycerol-3-phosphate dehydrogenase (anaerobic), large subunit, FAD/NAD(P)-binding protein; Protein involved in (DEPRECATED) electron donor activity, glycerol-3-phosphate dehydrogenase activity, oxidoreductase activity, anaerobic respiration, glycerol metabolic process, glycerol-3-phosphate metabolic process and (OBSOLETE) electron transport; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (547 aa) |
| | glpB | Sn-glycerol-3-phosphate dehydrogenase (anaerobic), membrane anchor subunit; Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor. (416 aa) |
| | glpD | Sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding protein; Protein involved in (DEPRECATED) electron donor activity, glycerol-3-phosphate dehydrogenase activity, oxidoreductase activity, aerobic respiration, glycerol metabolic process, glycerol-3-phosphate metabolic process and (OBSOLETE) electron transport; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (499 aa) |
| | nudE | ADP-ribose diphosphatase; Protein involved in hydrolase activity, carbohydrate catabolic process and folic acid biosynthetic process. (183 aa) |
| | ADM97915.1 | Malonate decarboxylase beta subunit; Protein involved in ligase activity. (277 aa) |
| | ribF | Bifunctional riboflavin kinase/FAD synthetase; Protein involved in riboflavin kinase activity, catalytic activity, riboflavin biosynthetic process and biosynthetic process; Belongs to the ribF family. (313 aa) |
| | mog | Putative molybdochelatase; Protein involved in Mo-molybdopterin cofactor biosynthetic process. (195 aa) |
| | talB | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (317 aa) |
| | ytjC | Phosphoglyceromutase 2, co-factor independent; Protein involved in catalytic activity, glycolysis, gluconeogenesis and metabolic process; Belongs to the phosphoglycerate mutase family. GpmB subfamily. (216 aa) |
| | yjjX | Hypothetical protein; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. (178 aa) |
| | rpiA | Ribose 5-phosphate isomerase, constitutive; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (220 aa) |
| | fbaA | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (358 aa) |
| | pgk | Protein involved in phosphoglycerate kinase activity, glycolysis and gluconeogenesis; Belongs to the phosphoglycerate kinase family. (387 aa) |
| | epd | D-erythrose 4-phosphate dehydrogenase; Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate. (338 aa) |
| | araA | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. (503 aa) |
| | araB | L-ribulokinase; Protein involved in ribulokinase activity, carbohydrate catabolic process, carbohydrate metabolic process and L-arabinose catabolic process. (561 aa) |
| | hrcN | Type III secretory pathway, ATPase component HrcN; E. coli containing D. dadantii hrp cluster is capable of secreting an exogenous effector into tobacco, eliciting a hypersensitive response; Protein involved in nucleotide binding, nucleoside-triphosphatase activity, hydrogen ion transporting ATP synthase activity, rotational mechanism, proton-transporting ATPase activity, rotational mechanism, ATP binding, ATPase activity, protein secretion by the type III secretion system, interaction with host via protein secreted by type III secretion system, ATP synthesis coupled proton transport, [...] (460 aa) |
| | ADM98711.1 | Protein involved in (DEPRECATED) molecular function unknown, inositol or phosphatidylinositol phosphatase activity and (DEPRECATED) biological process unknown. (275 aa) |
| | yhdE | Conserved protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (197 aa) |
| | amn | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. (487 aa) |
| | ADM97647.1 | 6-phosphogluconolactonase; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. (352 aa) |
| | thyA | Thymidylate synthetase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (243 aa) |
| | dxr | 1-deoxy-d-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP). (397 aa) |
| | pssA | Phosphatidylserine synthase (CDP-diacylglycerol-serine O-phosphatidyltransferase); Protein involved in catalytic activity, phospholipid biosynthetic process and metabolic process. (451 aa) |
| | pucG | Serine--pyruvate aminotransferase / L-alanine:glyoxylate aminotransferase; Protein involved in (DEPRECATED) molecular function unknown, catalytic activity, pyridoxal phosphate binding, transaminase activity, (DEPRECATED) biological process unknown and metabolic process. (424 aa) |
| | lpcA | D-sedoheptulose 7-phosphate isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (193 aa) |
| | gpt | Guanine-xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (152 aa) |
| | fdhD | Formate dehydrogenase formation protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (284 aa) |
| | glk | Glucokinase; Protein involved in glucokinase activity, ATP binding, carbohydrate catabolic process and glycolysis; Belongs to the bacterial glucokinase family. (322 aa) |
| | ADN00685.1 | Carbamoyl-phosphate synthase large chain; Protein involved in catalytic activity and ATP binding. (505 aa) |
| | arnF | Polymyxin resistance protein PmrM; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnF family. (132 aa) |
| | arnE | Polymyxin resistance protein PmrL, sucrose-6 phosphate hydrolase; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnE family. (113 aa) |
| | arnT | 4-amino-4-deoxy-L-arabinose transferase; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family. (552 aa) |
| | yfbH | Undecaprenyl phosphate-alpha-L-Ara4FN (4-deoxy-4-formamido-L-arabinose) deformylase; Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily. (299 aa) |
| | yfbG | Bifunctional UDP-L-Ara4N formyltransferase/UDP-GlcA C-4'-decarboxylase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the N-terminal section; belongs to the Fmt family. UDP- L-Ara4N formyltransferase subfamily. (663 aa) |
| | arnC | Undecaprenyl-phosphate 4-amino-4-deoxy-L-arabinose transferase; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. (327 aa) |
| | arnB | UDP-4-amino-4-deoxy-L-arabinose alpha-ketoglutarate aminotransferase; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily. (412 aa) |
| | ADN00751.1 | Argininosuccinate lyase; Protein involved in (DEPRECATED) molecular function unknown, catalytic activity, ATP binding and (DEPRECATED) biological process unknown. (391 aa) |
| | ADN00754.1 | Phosphoribosylglycinamide synthetase ATP-grasp (A) domain protein; Protein involved in (DEPRECATED) molecular function unknown, catalytic activity, ATP binding and (DEPRECATED) biological process unknown. (240 aa) |
| | mobB | Molybdopterin-guanine dinucleotide biosynthesis protein B; Protein involved in GTP binding and Mo-molybdopterin cofactor biosynthetic process. (175 aa) |
| | mobA | Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (196 aa) |
| | spoT | GTP pyrophosphokinase / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (700 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (207 aa) |
| | ADM96262.1 | Long-chain-fatty-acid--CoA ligase / long-chain acyl-CoA synthetase; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. (212 aa) |
| | plsC | Protein involved in acyltransferase activity, 1-acylglycerol-3-phosphate O-acyltransferase activity, phospholipid biosynthetic process and metabolic process; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (245 aa) |
| | nrdG | Anaerobic ribonucleotide reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (154 aa) |
| | pyrI | Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. (154 aa) |
| | pyrB | Aspartate carbamoyltransferase, catalytic subunit; Protein involved in carboxyl- or carbamoyltransferase activity, amino acid binding, aspartate carbamoyltransferase activity, pyrimidine nucleotide biosynthetic process, amino acid metabolic process and 'de novo' pyrimidine base biosynthetic process; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (311 aa) |
| | pdxA | 4-hydroxy-L-threonine phosphate dehydrogenase, NAD-dependent; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (333 aa) |
| | carB | Protein involved in catalytic activity, ATP binding, carbamoyl-phosphate synthase activity, ligase activity, arginine biosynthetic process, pyrimidine nucleotide biosynthetic process, metabolic process, pyrimidine base biosynthetic process and nitrogen compound metabolic process; Belongs to the CarB family. (1074 aa) |
| | carA | Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Protein involved in carbamoyl-phosphate synthase activity, ATP binding, catalytic activity, ligase activity, arginine biosynthetic process, pyrimidine nucleotide biosynthetic process, nitrogen compound metabolic process, biosynthetic process and glutamine metabolic process; Belongs to the CarA family. (381 aa) |
| | ispH | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase, 4Fe-4S protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. (316 aa) |
| | yffH | GDP-mannose pyrophosphatase; Protein involved in (DEPRECATED) molecular function unknown, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, metal ion binding, hydrolase activity and (DEPRECATED) biological process unknown. (194 aa) |
| | talA | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (316 aa) |
| | ADM97212.1 | DNA topology modulation protein flar-related protein; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. (175 aa) |
| | sucB | Dihydrolipoyltranssuccinase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (408 aa) |
| | ADM96471.1 | Protein involved in CTP synthase activity and pyrimidine nucleotide biosynthetic process. (259 aa) |
| | accC | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa) |
| | ADM98511.1 | Myo-inositol-1(or 4)-monophosphatase; Protein involved in inositol or phosphatidylinositol phosphatase activity and phosphorus metabolic process. (254 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (289 aa) |
| | lpxH | UDP-2,3-diacylglucosamine pyrophosphatase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (240 aa) |
| | purE | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (169 aa) |
| | purK | N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (356 aa) |
| | ppk | Polyphosphate kinase, component of RNA degradosome; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (689 aa) |
| | ybdQ | Protein involved in response to stress. (142 aa) |
| | yfaY | Protein involved in (DEPRECATED) molecular function unknown, (DEPRECATED) biological process unknown and Mo-molybdopterin cofactor biosynthetic process; Belongs to the CinA family. (397 aa) |
| | lpxD | UDP-3-O-(3-hydroxymyristoyl)-glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (340 aa) |
| | fabZ | (3R)-hydroxymyristol acyl carrier protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (151 aa) |
| | lpxA | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (262 aa) |
| | lpxB | tetraacyldisaccharide-1-P synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (382 aa) |
| | accA | acetyl-CoA carboxylase, carboxytransferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa) |
| | yaeR | Predicted lyase; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. (129 aa) |
| | ADM97331.1 | Phosphoserine phosphatase; Protein involved in (DEPRECATED) molecular function unknown, phosphatase activity, catalytic activity, (DEPRECATED) biological process unknown and metabolic process. (218 aa) |
| | thiL | Thiamin-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (324 aa) |
| | pgpA | Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). (170 aa) |
| | dxs | 1-deoxyxylulose-5-phosphate synthase, thiamine-requiring, FAD-requiring; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (620 aa) |
| | thiI | Sulfur transfer protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (482 aa) |
| | dcrB | DcrB protein precursor; Putative lipoproteine; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. (221 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (159 aa) |
| | gpsA | Glycerol-3-phosphate dehydrogenase (NAD+); Protein involved in oxidoreductase activity, coenzyme binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, NAD binding, oxidoreductase activity, acting on CH-OH group of donors, phospholipid biosynthetic process, glycerol metabolic process, phosphorus metabolic process, glycerol-3-phosphate catabolic process and carbohydrate metabolic process; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (339 aa) |
| | crcA | Lipid A acylation protein PagP, palmitoyltransferase; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors. (184 aa) |
| | udp | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. (253 aa) |
| | purB | Adenylosuccinate lyase; Protein involved in catalytic activity, adenylosuccinate lyase activity, purine nucleotide biosynthetic process and purine ribonucleotide biosynthetic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (455 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (505 aa) |
| | accD | acetyl-CoA carboxylase, beta (carboxyltransferase) subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (303 aa) |
| | pgi | Protein involved in glucose-6-phosphate isomerase activity, glycolysis and gluconeogenesis; Belongs to the GPI family. (549 aa) |
| | psd | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (304 aa) |
| | fliI | Flagellum-specific ATP synthase fliI; Protein involved in ATPase activity, ATP binding, hydrogen ion transporting ATP synthase activity, rotational mechanism, proton-transporting ATPase activity, rotational mechanism, nucleotide binding, nucleoside-triphosphatase activity, ATP synthesis coupled proton transport, biosynthetic process, protein transport, ciliary or flagellar motility and flagellum assembly. (456 aa) |
| | lpxC | UDP-3-O-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (305 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (208 aa) |
| | guaC | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (346 aa) |
| | nadC | Quinolinate phosphoribosyltransferase; Protein involved in catalytic activity, NAD biosynthetic process and metabolic process; Belongs to the NadC/ModD family. (296 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (217 aa) |
| | thiK | Thiamin kinase; Catalyzes the phosphorylation of thiamine to thiamine phosphate. (287 aa) |
| | ddg | Lipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of palmitoleate from palmitoleoyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (palmitoleoyl)-lipid IV(A); Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily. (326 aa) |
| | ADM96903.1 | GTP pyrophosphokinase; Protein involved in (DEPRECATED) molecular function unknown, (DEPRECATED) biological process unknown and guanosine tetraphosphate metabolic process. (329 aa) |
| | ADM96881.1 | Predicted hydrolase; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. (202 aa) |
| | ADM96861.1 | Putative glyoxylase resistance protein. (145 aa) |
| | deoB | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (407 aa) |
| | deoC | 2-deoxyribose-5-phosphate aldolase, NAD(P)-linked; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily. (259 aa) |
| | suhB | Myo-inositol-1(or 4)-monophosphatase; Protein involved in inositol or phosphatidylinositol phosphatase activity and transcription; Belongs to the inositol monophosphatase superfamily. (267 aa) |
| | acs | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (653 aa) |
| | corC | Predicted ion transport. (289 aa) |
| | nadD | Nicotinic acid mononucleotide adenylyltransferase, NAD(P)-dependent; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (224 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Protein involved in phosphoribosylaminoimidazolesuccinocarboxamide synthase activity, catalytic activity, ATP binding and purine nucleotide biosynthetic process; Belongs to the SAICAR synthetase family. (237 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (208 aa) |
| | purM | Phosphoribosylaminoimidazole synthetase; Protein involved in catalytic activity, phosphoribosylformylglycinamidine cyclo-ligase activity, purine nucleotide biosynthetic process and 'de novo' IMP biosynthetic process. (345 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (212 aa) |
| | lcfK | D-ribulokinase; Protein involved in carbohydrate catabolic process and carbohydrate metabolic process. (528 aa) |
| | yfjB | NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (292 aa) |
| | aas | 2-acylglycerophosphoethanolamine acyltransferase; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family. (732 aa) |
| | yggV | dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (197 aa) |
| | ADM99995.1 | Argininosuccinate lyase; Protein involved in (DEPRECATED) molecular function unknown, ATP binding, catalytic activity and (DEPRECATED) biological process unknown. (399 aa) |
| | pyrE-2 | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (213 aa) |
| | ADM96726.1 | GTP pyrophosphokinase / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; Protein involved in (DEPRECATED) molecular function unknown, catalytic activity and (DEPRECATED) biological process unknown. (215 aa) |
| | nadR | NadR transcriptional repressor / ribosylnicotinamide kinase / NMN adenylyltransferase; NadR is a bifunctional protein that is also involved in the transport of NAD; NadR belongs to the Cro/cI family of transcriptional regulators; Protein involved in transcription repressor activity, DNA binding, transcription regulator activity, catalytic activity, sequence-specific DNA binding, NAD biosynthetic process, transcription, transport, pyridine nucleotide biosynthetic process, regulation of transcription and biosynthetic process. (418 aa) |
| | plsB | Protein involved in acyltransferase activity, glycerol-3-phosphate O-acyltransferase activity, phospholipid biosynthetic process, cellular lipid metabolic process and metabolic process; Belongs to the GPAT/DAPAT family. (829 aa) |
| | dgkA | Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (121 aa) |
| | thiM | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (264 aa) |
| | thiD | Bifunctional hydroxy-methylpyrimidine kinase/hydroxy-phosphomethylpyrimidine kinase; Protein involved in phosphomethylpyrimidine kinase activity and thiamin biosynthetic process. (267 aa) |
| | cdh | Protein involved in CDP-diacylglycerol diphosphatase activity and phospholipid biosynthetic process. (255 aa) |
| | avrL | Avirulence protein; AvrL is secreted by the Out system; promoter is bound by pecS; Protein involved in metallopeptidase activity, zinc ion binding, interaction with host via protein secreted by type II secretion system and proteolysis. (618 aa) |
| | ADM96375.1 | Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. (209 aa) |
| | aceF | Pyruvate dehydrogenase, dihydrolipoyltransacetylase component E2; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (628 aa) |
| | aceE | Pyruvate dehydrogenase, decarboxylase component E1, thiamin-binding protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (887 aa) |
| | ygaD | Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown; Belongs to the CinA family. (162 aa) |
| | ADM99690.1 | Protein involved in phosphatidylserine decarboxylase activity and phospholipid biosynthetic process. (469 aa) |
| | lpxK | Lipid A 4'kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (337 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (213 aa) |
| | dut | Deoxyuridinetriphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (151 aa) |
| | dfp | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (428 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (214 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (184 aa) |
| | tesB | Protein involved in acyl-CoA thioesterase activity, xenobiotic metabolic process and acyl-CoA metabolic process. (287 aa) |
| | nadE | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (274 aa) |
| | purL | Phosphoribosylformyl-glycineamide synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1295 aa) |
| | yfhB | Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. (203 aa) |
| | ADM99039.1 | Carbamoyl-phosphate synthase small chain; Protein involved in (DEPRECATED) molecular function unknown, catalytic activity, ATP binding and (DEPRECATED) biological process unknown. (395 aa) |
