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| | yfiD | Pyruvate formate lyase subunit; Acts as a radical domain for damaged PFL and possibly other radical proteins. (127 aa) |
| | ADM99094.1 | Lactoylglutathione lyase-like lyase; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. (139 aa) |
| | ygjT | Protein involved in DNA photolyase activity, response to stress and DNA repair. (317 aa) |
| | uxaA | Altronate hydrolase; Protein involved in hydro-lyase activity and carbohydrate catabolic process. (496 aa) |
| | ubiC | Chorismate pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway. (171 aa) |
| | aspA | Protein involved in aspartate ammonia-lyase activity, catalytic activity, amino acid metabolic process, asparagine biosynthetic process, lysine biosynthetic process via diaminopimelate and aspartate metabolic process. (479 aa) |
| | dcyD | D-cysteine desulfhydrase, PLP-dependent; Protein involved in catalytic activity, amino acid catabolic process, sulfur metabolic process and metabolic process. (337 aa) |
| | acnB | Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Protein involved in aconitate hydratase activity, lyase activity, tricarboxylic acid cycle, aerobic respiration, anaerobic respiration, carbohydrate catabolic process, fatty acid oxidation and metabolic process; Belongs to the aconitase/IPM isomerase family. (865 aa) |
| | ADN00004.1 | Dihydrodipicolinate synthase; Protein involved in lyase activity, catalytic activity and metabolic process; Belongs to the DapA family. (294 aa) |
| | ADM99995.1 | Argininosuccinate lyase; Protein involved in (DEPRECATED) molecular function unknown, ATP binding, catalytic activity and (DEPRECATED) biological process unknown. (399 aa) |
| | lysA | Diaminopimelate decarboxylase, PLP-binding protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (420 aa) |
| | ADM96301.1 | Dihydrodipicolinate synthase; Protein involved in lyase activity, catalytic activity, lysine biosynthetic process via diaminopimelate and metabolic process; Belongs to the DapA family. (319 aa) |
| | uxuA | Mannonate dehydratase; Catalyzes the dehydration of D-mannonate. (394 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa) |
| | rlpA | Minor lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (387 aa) |
| | cbsE | 2,3-dihydroxybenzoate-AMP ligase, chrysobactin biosynthesis; Protein involved in catalytic activity, iron ion transport, nonribosomal peptide biosynthetic process, chrysobactin biosynthetic process, metabolic process and pathogenesis. (542 aa) |
| | truB | tRNA U55 pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (318 aa) |
| | deoC | 2-deoxyribose-5-phosphate aldolase, NAD(P)-linked; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily. (259 aa) |
| | budA | Alpha-acetolactate decarboxylase; Protein involved in carbohydrate catabolic process; Belongs to the alpha-acetolactate decarboxylase family. (262 aa) |
| | yceG | Conserved protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (343 aa) |
| | pabC | 4-amino-4-deoxychorismate lyase component of para-aminobenzoate synthase multienzyme complex; Protein involved in catalytic activity, folic acid biosynthetic process and metabolic process. (267 aa) |
| | nifS | Cysteine desulfurase; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. (411 aa) |
| | psd | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (304 aa) |
| | aceA | Protein involved in isocitrate lyase activity, catalytic activity, glyoxylate cycle, carbohydrate catabolic process, carboxylic acid metabolic process and metabolic process. (435 aa) |
| | truA | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (276 aa) |
| | purB | Adenylosuccinate lyase; Protein involved in catalytic activity, adenylosuccinate lyase activity, purine nucleotide biosynthetic process and purine ribonucleotide biosynthetic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (455 aa) |
| | fadB | Fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (729 aa) |
| | ADN00497.1 | Protein involved in porphobilinogen synthase activity, metal ion binding, catalytic activity, tetrapyrrole biosynthetic process and metabolic process; Belongs to the ALAD family. (340 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (879 aa) |
| | ADM97309.1 | Ornithine cyclodeaminase; Protein involved in nitrogen compound metabolic process, energy derivation by oxidation of organic compounds and amino acid metabolic process. (315 aa) |
| | yaeR | Predicted lyase; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. (129 aa) |
| | fabZ | (3R)-hydroxymyristol acyl carrier protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (151 aa) |
| | menC | o-succinylbenzoyl-CoA synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (322 aa) |
| | menB | Dihydroxynaphthoic acid synthetase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). (285 aa) |
| | yfbB | Predicted peptidase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). (266 aa) |
| | sdaB | L-serine deaminase II; Protein involved in L-serine ammonia-lyase activity, amino acid catabolic process and gluconeogenesis; Belongs to the iron-sulfur dependent L-serine dehydratase family. (456 aa) |
| | purK | N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (356 aa) |
| | purE | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (169 aa) |
| | ADM99427.1 | Histidine ammonia-lyase; Feature ID 17150 is homologous to 17139; Protein involved in ammonia ligase activity, histidine ammonia-lyase activity, biosynthetic process and histidine catabolic process. (500 aa) |
| | hutH | Histidine ammonia-lyase; Protein involved in ammonia ligase activity, histidine ammonia-lyase activity, amino acid catabolic process, nitrogen compound metabolic process, biosynthetic process and histidine catabolic process. (543 aa) |
| | hutU | Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (581 aa) |
| | ADM98519.1 | Phenolic acid decarboxylase; Protein involved in carboxy-lyase activity, xenobiotic metabolic process and carbohydrate catabolic process. (168 aa) |
| | rluD | 23S rRNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (325 aa) |
| | pheA | Protein involved in chorismate mutase activity, prephenate dehydratase activity, L-phenylalanine biosynthetic process, tyrosine biosynthetic process and aromatic amino acid family biosynthetic process. (393 aa) |
| | phr | Deoxyribodipyrimidine photolyase, FAD-binding protein; Protein involved in DNA photolyase activity and DNA repair. (476 aa) |
| | nei | Endonuclease VIII; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (262 aa) |
| | rhiE | Rhamnogalacturonate lyase precursor; Degrades the rhamnogalacturonan I (RG-I) backbone of pectin. Is required for the full virulence of E.chrysanthemi strain 3937 as it is involved in rotting of plant tissue; Belongs to the polysaccharide lyase 4 family. (578 aa) |
| | yeaU | Protein involved in tartrate dehydrogenase activity, NAD binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, fermentation and metabolic process. (361 aa) |
| | ADM99503.1 | Putative transmembrane protein. (555 aa) |
| | ADM99500.1 | Lactoylglutathione lyase-like lyase; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. (156 aa) |
| | mgsA | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (152 aa) |
| | acsB | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Protein involved in carbon-carbon lyase activity, iron ion transport, achromobactin biosynthetic process, cellular aromatic compound metabolic process and pathogenesis; Belongs to the HpcH/HpaI aldolase family. (258 aa) |
| | acsE | Diaminopimelate decarboxylase; Protein involved in catalytic activity, iron ion transport, achromobactin biosynthetic process, polyamine biosynthetic process and pathogenesis; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (411 aa) |
| | rhaD | Rhamnulose-1-phosphate aldolase; Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. Belongs to the aldolase class II family. RhaD subfamily. (278 aa) |
| | cyaB | Protein involved in adenylate cyclase activity, nucleobase, nucleoside and nucleotide interconversion and cAMP biosynthetic process. (179 aa) |
| | hrpW | Type III secreted protein; HR-eliciting activity; Protein involved in pectate lyase activity, interaction with host via protein secreted by type III secretion system and pathogenesis. (569 aa) |
| | ADM98281.1 | Fumarylacetoacetate hydrolase family protein; Protein involved in catalytic activity, fatty acid oxidation and metabolic process. (294 aa) |
| | hisB | Bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase; Protein involved in imidazoleglycerol-phosphate dehydratase activity, histidinol-phosphatase activity and histidine biosynthetic process. (355 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit with HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (196 aa) |
| | hisF | Imidazole glycerol phosphate synthase, catalytic subunit with HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (258 aa) |
| | tdcB | Catabolic threonine dehydratase, PLP-dependent; Protein involved in catalytic activity, amino acid catabolic process, metabolic process and amino acid metabolic process. (322 aa) |
| | ADM97898.1 | Dihydrodipicolinate synthase; Protein involved in lyase activity, catalytic activity and metabolic process; Belongs to the DapA family. (294 aa) |
| | ADM99690.1 | Protein involved in phosphatidylserine decarboxylase activity and phospholipid biosynthetic process. (469 aa) |
| | ADM98300.1 | Pectate lyase; Protein involved in carbohydrate catabolic process and polysaccharide catabolic process. (439 aa) |
| | virA | Protein involved in catalytic activity, diaminopimelate decarboxylase activity and lysine biosynthetic process via diaminopimelate. (440 aa) |
| | dfp | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (428 aa) |
| | mutM | Formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (269 aa) |
| | hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (320 aa) |
| | pflB | Protein involved in formate C-acetyltransferase activity, catalytic activity, anaerobic respiration, amino acid catabolic process, glucose metabolic process, metabolic process and carbohydrate metabolic process. (760 aa) |
| | pflA | Pyruvate formate lyase activating enzyme 1; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (246 aa) |
| | pelW | Exopolygalacturonate lyase; Catalyzes the formation of unsaturated digalacturonates from polygalacturonate or short oligogalacturonates. Belongs to the polysaccharide lyase 2 family. (543 aa) |
| | pelA | Pectate lyase, Pla; Involved in maceration and soft-rotting of plant tissue. (392 aa) |
| | leuD | 3-isopropylmalate isomerase subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (200 aa) |
| | tnaA | Tryptophanase; Protein involved in catalytic activity, pyridoxal phosphate binding, carbon-carbon lyase activity, lyase activity, tryptophanase activity, amino acid catabolic process, aromatic amino acid family metabolic process, amino acid metabolic process and tryptophan metabolic process; Belongs to the beta-eliminating lyase family. (466 aa) |
| | rluA | Protein involved in RNA binding, pseudouridine synthase activity, pseudouridylate synthase activity, RNA modification and RNA processing. (235 aa) |
| | ADM97142.1 | Enoyl-CoA hydratase; Protein involved in (DEPRECATED) molecular function unknown, catalytic activity, (DEPRECATED) biological process unknown and metabolic process. (321 aa) |
| | ribB | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (217 aa) |
| | fumA | Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (547 aa) |
| | pelE | Pectate lyase pelE; Involved in maceration and soft-rotting of plant tissue. Pectate lyases have been implicated as pathogenicity factors which induce maceration or rotting of plant tissue. PelE is sufficient to induce these effects under laboratory conditions. (404 aa) |
| | pelD | Pectate lyase D; PelE is secreted by the Out secretion system; Protein involved in pectate lyase activity, polysaccharide catabolic process, carbohydrate catabolic process, interaction with host via protein secreted by type II secretion system, metabolism by symbiont of substance in host and pathogenesis. (392 aa) |
| | yfhD | Lytic transglycosylase; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. (485 aa) |
| | yfeU | Glucokinase regulatory protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily. (307 aa) |
| | ADM99564.1 | Tryptophan synthase beta chain like protein; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. (127 aa) |
| | mltC | Membrane-bound lytic murein transglycosylase C; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. (360 aa) |
| | speC | Ornithine decarboxylase, constitutive; Protein involved in catalytic activity, pyridoxal phosphate binding, carboxy-lyase activity, polyamine biosynthetic process and amino acid metabolic process. (717 aa) |
| | fabA | Beta-hydroxydecanoyl thioester dehydrase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (172 aa) |
| | ADM99934.1 | Arogenate dehydratase; Protein involved in transporter activity, L-phenylalanine biosynthetic process and transport. (288 aa) |
| | ADM96804.1 | Pectate lyase; Homologous to type III helper protein HopPmaH. However, this protein has cysteines, while HopPmaH lacks cysteines - a characteristic of type III helper proteins. Therefore, this is not likely to be a type III helper; Protein involved in polysaccharide catabolic process, protein secretion by the type II secretion system, interaction with host via protein secreted by type II secretion system and metabolism by symbiont of host cell wall pectin. (315 aa) |
| | kdgA | 2-dehydro-3-deoxyphosphogluconate aldolase; Protein involved in catalytic activity, carbohydrate catabolic process, Entner-Doudoroff pathway, glyoxylate catabolic process and metabolic process; Belongs to the KHG/KDPG aldolase family. (213 aa) |
| | cynS | Cyanate hydratase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family. (156 aa) |
| | ADM97963.1 | Carbonic anhydrase; Protein involved in carbonate dehydratase activity, zinc ion binding, cyanate catabolic process, xenobiotic metabolic process and carbon utilization. (104 aa) |
| | sufS | Cysteine desulfurase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily. (412 aa) |
| | ogl | Oligogalacturonate lyase; Involved in degradation of pectin, which causes soft-rod disease in plants. (388 aa) |
| | pabB | Aminodeoxychorismate synthase, subunit I; Protein involved in oxo-acid-lyase activity, folic acid biosynthetic process, biosynthetic process and folic acid and derivative biosynthetic process. (487 aa) |
| | sdaA | Protein involved in L-serine ammonia-lyase activity and gluconeogenesis; Belongs to the iron-sulfur dependent L-serine dehydratase family. (453 aa) |
| | moaA | Molybdopterin biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (329 aa) |
| | moaC | Molybdopterin biosynthesis, protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (160 aa) |
| | rsuA | 16S rRNA pseudouridylate 516 synthase; Protein involved in RNA binding, pseudouridine synthase activity, pseudouridylate synthase activity, RNA modification and RNA processing; Belongs to the pseudouridine synthase RsuA family. (232 aa) |
| | pelI | Endo-pectate lyase; PelI is secreted by the Out secretion system; Protein involved in pectate lyase activity, interaction with host via protein secreted by type II secretion system, metabolism by symbiont of substance in host, pathogenesis and pectin catabolic process. (344 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (165 aa) |
| | rffG | dTDP-glucose 4,6-dehydratase; Protein involved in (OBSOLETE) cell surface antigen activity, host-interacting, catalytic activity, coenzyme binding, dTDP-glucose 4,6-dehydratase activity, O antigen biosynthetic process, enterobacterial common antigen biosynthetic process, NAD biosynthetic process, cellular metabolic process and nucleotide-sugar metabolic process; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (354 aa) |
| | ADM97596.1 | Putative sugar ABC transporter; Protein involved in (DEPRECATED) molecular function unknown, 3-dehydroquinate dehydratase activity, (DEPRECATED) biological process unknown and aromatic amino acid family biosynthetic process. (358 aa) |
| | luxS | S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (171 aa) |
| | speD | S-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. (264 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (164 aa) |
| | pyrF | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (244 aa) |
| | acnA | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (892 aa) |
| | adhE | Protein involved in alcohol dehydrogenase activity, oxidoreductase activity, metal ion binding, fermentation, cellular alcohol metabolic process and metabolic process; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (900 aa) |
| | can | Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (213 aa) |
| | phnJ | PhnJ protein; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. Belongs to the PhnJ family. (284 aa) |
| | pnlH | Pectate lyase; Protein involved in carbohydrate catabolic process, polysaccharide catabolic process, protein secretion by the type II secretion system, interaction with host via protein secreted by type II secretion system and metabolism by symbiont of substance in host. (310 aa) |
| | fumC | Fumarate hydratase (fumarase C),aerobic Class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa) |
| | ybaK | Bifunctional cys-tRNA Pro deacetylase/cys-tRNA Cys deacylase; Protein involved in (DEPRECATED) molecular function unknown, (DEPRECATED) biological process unknown and regulation of transcription, DNA-dependent; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (159 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (361 aa) |
| | pelZ | Pectate lyase; PelZ is secreted by the Out secretion system; Protein involved in pectate lyase activity, interaction with host via protein secreted by type II secretion system, metabolism by symbiont of substance in host, pectin catabolic process and pathogenesis. (425 aa) |
| | pelC | Pectate lyase C; PelC is secretd by the Out secretion system; Protein involved in polysaccharide catabolic process, carbohydrate catabolic process and pathogenesis. (374 aa) |
| | pelB | Pectate lyase B; PelB is secreted by the Out secretion system; Protein involved in pectate lyase activity, polysaccharide catabolic process, interaction with host via protein secreted by type II secretion system, metabolism by symbiont of substance in host and pathogenesis. (375 aa) |
| | rluC | Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (318 aa) |
| | citC_2 | Citrate lyase synthetase; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase. (347 aa) |
| | citD_2 | Citrate lyase, acyl carrier (gamma) subunit; Covalent carrier of the coenzyme of citrate lyase. (96 aa) |
| | citE_2 | Citrate lyase, citryl-ACP lyase (beta) subunit; Protein involved in carbon-carbon lyase activity, citryl-CoA lyase activity, cellular aromatic compound metabolic process and acetyl-CoA metabolic process; Belongs to the HpcH/HpaI aldolase family. (297 aa) |
| | citC_1 | Citrate lyase synthetase; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase. (347 aa) |
| | citE_1 | Citrate lyase, citryl-ACP lyase (beta) subunit; Protein involved in carbon-carbon lyase activity, citryl-CoA lyase activity, cellular aromatic compound metabolic process and acetyl-CoA metabolic process; Belongs to the HpcH/HpaI aldolase family. (297 aa) |
| | citX | Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase. (180 aa) |
| | gloA | Glyoxalase I, Ni-dependent; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (135 aa) |
| | argH | Argininosuccinate lyase; Protein involved in catalytic activity, argininosuccinate lyase activity, arginine biosynthetic process and arginine biosynthetic process via ornithine. (457 aa) |
| | ADM97623.1 | dTDP-glucose 4,6-dehydratase; Protein involved in racemase and epimerase activity, acting on carbohydrates and derivatives, catalytic activity, coenzyme binding, carbohydrate catabolic process, carbohydrate metabolic process and cellular metabolic process. (335 aa) |
| | leuC | 3-isopropylmalate isomerase subunit, dehydratase component; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (466 aa) |
| | metC | Cystathionine beta-lyase, PLP-dependent; Protein involved in cystathionine beta-lyase activity, catalytic activity, pyridoxal phosphate binding, methionine biosynthetic process, cysteine biosynthetic process, sulfur metabolic process, nitrogen compound metabolic process and amino acid metabolic process. (397 aa) |
| | ADM97003.1 | Outer membrane protein; Protein involved in transporter activity, lipid binding, transport and amino acid metabolic process. (492 aa) |
| | menC-2 | O-succinylbenzoate-CoA synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (370 aa) |
| | mocC | Inosose dehydratase; Protein involved in carbohydrate catabolic process. (311 aa) |
| | dsdA | D-serine dehydratase; Protein involved in catalytic activity, D-serine ammonia-lyase activity, pyridoxal phosphate binding, L-serine biosynthetic process, amino acid catabolic process, metabolic process and D-amino acid metabolic process. (472 aa) |
| | ADN00751.1 | Argininosuccinate lyase; Protein involved in (DEPRECATED) molecular function unknown, catalytic activity, ATP binding and (DEPRECATED) biological process unknown. (391 aa) |
| | yfbG | Bifunctional UDP-L-Ara4N formyltransferase/UDP-GlcA C-4'-decarboxylase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the N-terminal section; belongs to the Fmt family. UDP- L-Ara4N formyltransferase subfamily. (663 aa) |
| | yfdU | Probable oxalyl-CoA decarboxylase; Protein involved in magnesium ion binding, transferase activity, thiamin pyrophosphate binding, carbon-carbon lyase activity, catalytic activity and carbohydrate catabolic process; Belongs to the TPP enzyme family. (581 aa) |
| | ADN00671.1 | Alkylhydroperoxidase AhpD domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (372 aa) |
| | indA | Indigoidine biosynthesis protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (316 aa) |
| | mtnB | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. (204 aa) |
| | truC | tRNA pseudouridine synthase; Protein involved in pseudouridylate synthase activity, RNA binding, pseudouridine synthase activity, RNA modification and RNA processing. (261 aa) |
| | csdA | Cysteine desulfurase; Protein involved in transaminase activity, catalytic activity, pyridoxal phosphate binding and metabolic process. (401 aa) |
| | mltA | Membrane-bound lytic murein transglycosylase A; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. (384 aa) |
| | ADM96554.1 | Putative exported protein. (461 aa) |
| | elbB | Small RNA; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate; Belongs to the peptidase C56 family. (217 aa) |
| | nth | DNA glycosylase and apyrimidinic (AP) lyase (endonuclease III); DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (211 aa) |
| | rluB | Protein involved in RNA binding, pseudouridylate synthase activity, pseudouridine synthase activity, RNA modification and RNA processing; Belongs to the pseudouridine synthase RsuA family. (296 aa) |
| | trpE | Protein involved in anthranilate synthase activity, oxo-acid-lyase activity, tryptophan biosynthetic process and biosynthetic process. (520 aa) |
| | trpG | Anthranilate synthase component II; Protein involved in catalytic activity, ligase activity, anthranilate synthase activity, tryptophan biosynthetic process, biosynthetic process, glutamine metabolic process and metabolic process. (192 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (338 aa) |
| | trpC | Protein involved in catalytic activity, indole-3-glycerol-phosphate synthase activity, phosphoribosylanthranilate isomerase activity, tryptophan biosynthetic process, metabolic process and tryptophan metabolic process; Belongs to the TrpC family. (461 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (396 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (269 aa) |
| | pabA | Aminodeoxychorismate synthase, subunit II; Protein involved in anthranilate synthase activity, catalytic activity, ligase activity, folic acid biosynthetic process, metabolic process, biosynthetic process and glutamine metabolic process. (191 aa) |
| | ADN00322.1 | Oxalate decarboxylase oxdD; Protein involved in nutrient reservoir activity and xenobiotic metabolic process. (416 aa) |
| | ADN00344.1 | Glutamate decarboxylase; Protein involved in (DEPRECATED) molecular function unknown, carboxy-lyase activity, catalytic activity, pyridoxal phosphate binding, (DEPRECATED) biological process unknown and carboxylic acid metabolic process. (456 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (126 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (361 aa) |
| | yfcX | Fatty acid oxidation complex subunit alpha; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities. Belongs to the enoyl-CoA hydratase/isomerase family. In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (746 aa) |
| | citF_1 | Citrate lyase alpha chain; Protein involved in citrate CoA-transferase activity, tricarboxylic acid cycle and acetyl-CoA metabolic process. (509 aa) |
| | gmd | GDP-D-mannose dehydratase, NAD(P)-binding protein; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (372 aa) |
| | yjeF | Predicted carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] (513 aa) |
| | speA | Biosynthetic arginine decarboxylase, PLP-binding protein; Catalyzes the biosynthesis of agmatine from arginine. (658 aa) |
| | fbaA | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (358 aa) |
| | thrC | Threonine synthase; Protein involved in catalytic activity, threonine synthase activity, threonine biosynthetic process, metabolic process and amino acid metabolic process. (429 aa) |
| | pck | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (539 aa) |
| | ADN00385.1 | Dihydrodipicolinate synthase; Protein involved in catalytic activity, lyase activity, amino acid metabolic process and metabolic process; Belongs to the DapA family. (308 aa) |
| | cyaA | Protein involved in adenylate cyclase activity, nucleobase, nucleoside and nucleotide interconversion and cAMP biosynthetic process; Belongs to the adenylyl cyclase class-1 family. (852 aa) |
| | hemD | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (246 aa) |
| | ADN00444.1 | Adenylosuccinate lyase; Protein involved in catalytic activity, adenylosuccinate lyase activity, metabolic process and purine ribonucleotide biosynthetic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (454 aa) |
| | ilvA | Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (514 aa) |
| | ilvD | Dihydroxyacid dehydratase; Protein involved in catalytic activity, dihydroxy-acid dehydratase activity, metabolic process and branched chain family amino acid biosynthetic process; Belongs to the IlvD/Edd family. (616 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (357 aa) |
| | thiC | Thiamin (pyrimidine moiety) biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (655 aa) |
| | cysG1 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (473 aa) |
| | pelL | Pectate lyase pelL; Presents an endo-cleaving activity on polygalacturonate or partially methylated pectin. Is effective in the maceration of plant tissue, and has an important role in soft-rot disease. Is 280-fold less active against polygalacturonate than the major pectate lyase PelB. When assayed on polygalacturonate, PelL releases oligogalacturonates of different sizes; upon prolonged incubation, PelL degrades the primary products to unsaturated tetramer and pentamer in addition to unsaturated dimer and trimer. When assayed on oligogalacturonates (degrees of polymerization of 2 to [...] (425 aa) |
| | ygcM | 6-carboxy-5,6,7,8-tetrahydropterin synthase; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. (122 aa) |
| | ygcF | Conserved protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (223 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (432 aa) |
| | garL | alpha-dehydro-beta-deoxy-D-glucarate aldolase; Catalyzes the reversible retro-aldol cleavage of both 5-keto- 4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde; Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily. (256 aa) |
| | gudD | D-glucarate dehydratase; Protein involved in catalytic activity, carbohydrate catabolic process and metabolic process. (446 aa) |
| | gudX | D-glucarate dehydratase-related protein; Protein involved in (DEPRECATED) molecular function unknown, catalytic activity, (DEPRECATED) biological process unknown and metabolic process. (453 aa) |
| | garD | (D)-galactarate dehydrogenase; Catalyzes the dehydration of galactarate to form 5-dehydro-4- deoxy-D-glucarate. (529 aa) |
| | ygiF | Predicted adenylate cyclase; Protein involved in (DEPRECATED) molecular function unknown, adenylate cyclase activity, (DEPRECATED) biological process unknown and cAMP biosynthetic process. (443 aa) |
| | folB | Bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (121 aa) |
| | pelX | Exopolygalacturonate lyase PelX; Protein involved in pectate lyase activity, polysaccharide catabolic process, interaction with host via protein secreted by type II secretion system, metabolism by symbiont of substance in host and pectin catabolic process. (734 aa) |
| | chaC | Cation transport protein chaC; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (225 aa) |
| | ubiX | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (189 aa) |
