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pelZ pelZ pelX pelX pehX pehX dnaK dnaK mtlD mtlD gyrB gyrB rhiE rhiE gyrA gyrA ganB ganB pelL pelL dnaX dnaX gapA gapA pelW pelW pelA pelA pemA pemA pemB pemB ogl ogl acnA acnA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
pelZPectate lyase; PelZ is secreted by the Out secretion system; Protein involved in pectate lyase activity, interaction with host via protein secreted by type II secretion system, metabolism by symbiont of substance in host, pectin catabolic process and pathogenesis. (425 aa)
pelXExopolygalacturonate lyase PelX; Protein involved in pectate lyase activity, polysaccharide catabolic process, interaction with host via protein secreted by type II secretion system, metabolism by symbiont of substance in host and pectin catabolic process. (734 aa)
pehXExo-poly-alpha-D-galacturonosidase precursor; Protein involved in polygalacturonase activity, pectate lyase activity, polysaccharide catabolic process, carbohydrate catabolic process, interaction with host via protein secreted by type II secretion system, metabolism by symbiont of substance in host, carbohydrate metabolic process, pectin catabolic process and metabolism by symbiont of host cell wall pectin; Belongs to the glycosyl hydrolase 28 family. (602 aa)
dnaKChaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (636 aa)
mtlDMannitol-1-phosphate dehydrogenase, NAD(P)-binding protein; Protein involved in oxidoreductase activity, coenzyme binding, catalytic activity, carbohydrate catabolic process and metabolic process. (382 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (803 aa)
rhiERhamnogalacturonate lyase precursor; Degrades the rhamnogalacturonan I (RG-I) backbone of pectin. Is required for the full virulence of E.chrysanthemi strain 3937 as it is involved in rotting of plant tissue; Belongs to the polysaccharide lyase 4 family. (578 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (877 aa)
ganB1,4-beta-exogalactanase; Protein involved in catalytic activity, cation binding, carbohydrate catabolic process and carbohydrate metabolic process. (685 aa)
pelLPectate lyase pelL; Presents an endo-cleaving activity on polygalacturonate or partially methylated pectin. Is effective in the maceration of plant tissue, and has an important role in soft-rot disease. Is 280-fold less active against polygalacturonate than the major pectate lyase PelB. When assayed on polygalacturonate, PelL releases oligogalacturonates of different sizes; upon prolonged incubation, PelL degrades the primary products to unsaturated tetramer and pentamer in addition to unsaturated dimer and trimer. When assayed on oligogalacturonates (degrees of polymerization of 2 to [...] (425 aa)
dnaXDNA polymerase III/DNA elongation factor III, tau and gamma subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (672 aa)
gapAProtein involved in glyceraldehyde-3-phosphate dehydrogenase activity, NAD binding, glycolysis, pyridoxine biosynthetic process, gluconeogenesis and glucose metabolic process. (331 aa)
pelWExopolygalacturonate lyase; Catalyzes the formation of unsaturated digalacturonates from polygalacturonate or short oligogalacturonates. Belongs to the polysaccharide lyase 2 family. (543 aa)
pelAPectate lyase, Pla; Involved in maceration and soft-rotting of plant tissue. (392 aa)
pemAPectinesterase; Involved in maceration and soft-rotting of plant tissue. (366 aa)
pemBPossible pectinesterase; Probably involved in the degradation of methylated oligogalacturonides present in the periplasm. (433 aa)
oglOligogalacturonate lyase; Involved in degradation of pectin, which causes soft-rod disease in plants. (388 aa)
acnAAconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (892 aa)
Your Current Organism:
Dickeya dadantii
NCBI taxonomy Id: 198628
Other names: D. dadantii 3937, Dickeya dadantii 3937, Dickeya dadantii str. 3937, Dickeya dadantii strain 3937, Erwinia chrysanthemi str. 3937, Pectobacterium chrysanthemi str. 3937
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