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hrcU hrcU ADM98371.1 ADM98371.1 pehW pehW tktA tktA parE parE rhiE rhiE prtG prtG rhsA rhsA celY celY nagZ nagZ ganK ganK ganA ganA celH celH virB5 virB5 virB2 virB2 virB1 virB1 flhD flhD cel5Z cel5Z cas2 cas2 xynA xynA kdgM kdgM paeX paeX paeY paeY fliZ fliZ fliA fliA fliC fliC pemB pemB lfaA lfaA ogl ogl bgxA bgxA arbB arbB prtA prtA wza wza pnlH pnlH hrpN hrpN gnd gnd acpP acpP
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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co-expression
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hrcUType III secretion inner membrane protein; E. coli containing D. dadantii hrp cluster is capable of secreting an exogenous effector into tobacco, eliciting a hypersensitive response; Protein involved in protein secretion by the type III secretion system, interaction with host via protein secreted by type III secretion system, protein secretion, transport and pathogenesis. (359 aa)
ADM98371.1Endonuclease; Protein involved in (DEPRECATED) molecular function unknown, nucleic acid binding, endonuclease activity and (DEPRECATED) biological process unknown. (246 aa)
pehWPolygalacturonase; Protein involved in polygalacturonase activity, carbohydrate catabolic process, polysaccharide catabolic process, metabolism by symbiont of host cell wall pectin, interaction with host via protein secreted by type II secretion system and carbohydrate metabolic process; Belongs to the glycosyl hydrolase 28 family. (606 aa)
tktATransketolase 1, thiamin-binding protein; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (664 aa)
parETopoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (631 aa)
rhiERhamnogalacturonate lyase precursor; Degrades the rhamnogalacturonan I (RG-I) backbone of pectin. Is required for the full virulence of E.chrysanthemi strain 3937 as it is involved in rotting of plant tissue; Belongs to the polysaccharide lyase 4 family. (578 aa)
prtGSecreted protease C precursor; Protein involved in calcium ion binding, metallopeptidase activity, zinc ion binding, metalloendopeptidase activity, nitrogen compound metabolic process, amino acid catabolic process, modulation by symbiont of host protease activity, interaction with host via protein secreted by type II secretion system and proteolysis. (477 aa)
rhsARhs-family protein; Toxic component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system. This protein may be a nuclease that is specifically inhibited by its cognate immunity protein RhsAI. Upon expression of the C- terminus (residues 1284-1434) in E.coli growth is inhibited, cells elongate, nucleoids condense and plasmid DNA is degraded; these effects are blocked specifically by cognate immunity protein RshIA. Cell contact is necessary for growth inhibition. (1434 aa)
celYEndoglucanase Y; Represents only 3% of the global cellulase activity; Belongs to the glycosyl hydrolase 8 (cellulase D) family. (332 aa)
nagZbeta-N-acetylglucosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (341 aa)
ganKATP-binding component of transport system for galactan; Protein involved in (OBSOLETE) ATP-binding cassette (ABC) transporter activity, ATP binding, ATPase activity, nucleotide binding and nucleoside-triphosphatase activity; Belongs to the ABC transporter superfamily. (369 aa)
ganAPeriplasmic 1,4-beta-endogalactanase; Protein involved in (DEPRECATED) molecular function unknown, glucosidase activity, catalytic activity, cation binding, (DEPRECATED) biological process unknown and carbohydrate metabolic process. (399 aa)
celHBeta-glucosidase; Protein involved in hydrolase activity, hydrolyzing O-glycosyl compounds, catalytic activity, cation binding, carbohydrate catabolic process and carbohydrate metabolic process; Belongs to the glycosyl hydrolase 1 family. (478 aa)
virB5Minor pilin of type IV secretion complex (VirB5). (238 aa)
virB2Major pilus subunit of type IV secretion complex (VirB2). (93 aa)
virB1VirB1; Bores hole in peptidoglycan layer allowing type IV secretion complex assembly to occur; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. (228 aa)
flhDFlagellar transcriptional activator flhD; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family. (116 aa)
cel5ZEndo-1,4-beta-glucanase precursor; Represents 97% of the global cellulase activity. (426 aa)
cas2CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (97 aa)
xynAXylanase; Protein involved in catalytic activity, cation binding, glucosylceramidase activity, endo-1,4-beta-xylanase activity, carbohydrate catabolic process, glucose metabolic process, polysaccharide catabolic process, metabolism by symbiont of substance in host, carbohydrate metabolic process, sphingolipid metabolic process and lysosome organization; Belongs to the glycosyl hydrolase 30 family. (413 aa)
kdgMOligogalacturonate specific porin; Porin specific for oligogalacturonides. Also required for full virulence; Belongs to the oligogalacturonate-specific porin KdgM (TC 1.B.35) family. (236 aa)
paeXProtein involved in acetylesterase activity, metabolism by symbiont of host cell wall pectin, interaction with host via protein secreted by type II secretion system, pathogenesis and pectin catabolic process. (322 aa)
paeYPectin acetylesterase; PaeY is secreted by the Out secretion system; Protein involved in hydrolase activity, acetylesterase activity, polysaccharide catabolic process, carbohydrate catabolic process, metabolism by symbiont of host cell wall pectin, interaction with host via protein secreted by type II secretion system, pathogenesis and entry into host. (551 aa)
fliZPredicted regulator of FliA activity. (170 aa)
fliARNA polymerase, sigma 28 (sigma F) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (240 aa)
fliCFlagellar filament structural protein (flagellin); Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (280 aa)
pemBPossible pectinesterase; Probably involved in the degradation of methylated oligogalacturonides present in the periplasm. (433 aa)
lfaAAlpha-glucosidase; Protein involved in hydrolase activity, hydrolyzing O-glycosyl compounds, polysaccharide catabolic process and carbohydrate metabolic process; Belongs to the glycosyl hydrolase 31 family. (791 aa)
oglOligogalacturonate lyase; Involved in degradation of pectin, which causes soft-rod disease in plants. (388 aa)
bgxABeta-glucosidase (Gentiobiase) (Cellobiase) / Beta- xylosidase; Protein involved in hydrolase activity, hydrolyzing O-glycosyl compounds, polysaccharide catabolic process and carbohydrate metabolic process. (671 aa)
arbBPhospho-beta-glucosidase; Protein involved in hydrolase activity, hydrolyzing O-glycosyl compounds, catalytic activity, cation binding, carbohydrate catabolic process and carbohydrate metabolic process; Belongs to the glycosyl hydrolase 1 family. (466 aa)
prtASecreted protease A precursor; Protein involved in calcium ion binding, metallopeptidase activity, zinc ion binding, metalloendopeptidase activity, peptidase activity, modulation by symbiont of host protease activity, interaction with host via protein secreted by type II secretion system, proteolysis and protein catabolic process. (477 aa)
wzaCapsule polysaccharide export protein; Protein involved in (OBSOLETE) cell surface antigen activity, host-interacting, polysaccharide transmembrane transporter activity and polysaccharide transport. (378 aa)
pnlHPectate lyase; Protein involved in carbohydrate catabolic process, polysaccharide catabolic process, protein secretion by the type II secretion system, interaction with host via protein secreted by type II secretion system and metabolism by symbiont of substance in host. (310 aa)
hrpNHarpin hrpN; E. coli containing D. dadantii hrp cluster is capable of secreting an exogenous effector into tobacco, eliciting a hypersensitive response; Protein involved in pellicle formation, pathogenesis and interaction with host via protein secreted by type III secretion system. (342 aa)
gndGluconate-6-phosphate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (468 aa)
acpPAcyl carrier protein (ACP); Carrier of the growing fatty acid chain in fatty acid biosynthesis. (78 aa)
Your Current Organism:
Dickeya dadantii
NCBI taxonomy Id: 198628
Other names: D. dadantii 3937, Dickeya dadantii 3937, Dickeya dadantii str. 3937, Dickeya dadantii strain 3937, Erwinia chrysanthemi str. 3937, Pectobacterium chrysanthemi str. 3937
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