STRINGSTRING
hecB hecB hrpN hrpN pnlH pnlH prtC prtC arbB arbB bgxA bgxA prt1 prt1 kdgR kdgR lfaA lfaA pemB pemB pemA pemA pelI pelI pelX pelX pehK pehK gntR gntR pecT pecT slyA slyA avrM avrM nipE nipE pecS pecS rhiE rhiE prtG prtG celY celY nagZ nagZ celH celH pelL pelL acsB acsB bglX bglX hrpW hrpW avrL avrL pelW pelW paeY paeY prtB prtB pelB pelB pelC pelC pelZ pelZ pehN pehN
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hecBHemolysin activator protein precursor; Probable outer membrane protein component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system. CDI modules allow bacteria to communicate with and inhibit the growth of closely related neighboring bacteria in a contact-dependent fashion. This protein may be required for secretion and assembly of the CdiA toxin; Belongs to the TPS (TC 1.B.20) family. (558 aa)
hrpNHarpin hrpN; E. coli containing D. dadantii hrp cluster is capable of secreting an exogenous effector into tobacco, eliciting a hypersensitive response; Protein involved in pellicle formation, pathogenesis and interaction with host via protein secreted by type III secretion system. (342 aa)
pnlHPectate lyase; Protein involved in carbohydrate catabolic process, polysaccharide catabolic process, protein secretion by the type II secretion system, interaction with host via protein secreted by type II secretion system and metabolism by symbiont of substance in host. (310 aa)
prtCSecreted protease C precursor; Protein involved in calcium ion binding, metallopeptidase activity, zinc ion binding, metalloendopeptidase activity, peptidase activity, modulation by symbiont of host protease activity, interaction with host via protein secreted by type II secretion system, proteolysis and protein catabolic process. (479 aa)
arbBPhospho-beta-glucosidase; Protein involved in hydrolase activity, hydrolyzing O-glycosyl compounds, catalytic activity, cation binding, carbohydrate catabolic process and carbohydrate metabolic process; Belongs to the glycosyl hydrolase 1 family. (466 aa)
bgxABeta-glucosidase (Gentiobiase) (Cellobiase) / Beta- xylosidase; Protein involved in hydrolase activity, hydrolyzing O-glycosyl compounds, polysaccharide catabolic process and carbohydrate metabolic process. (671 aa)
prt1Extracellular metalloprotease precursor; Extracellular zinc metalloprotease. (349 aa)
kdgRDNA-binding transcriptional regulatory protein KdgR; KdgR interacts with 2-keto-3-deoxygluconate which is an inducer; The consensus KdgR-binding site is ATRAAAYRNYRTTTYAT; KdgR belongs to the IclR family of transcriptional regulator; Protein involved in DNA binding, transcription repressor activity, metabolism by symbiont of host cell wall pectin, regulation of transcription, DNA-dependent, negative regulation of transcription and pathogenesis. (263 aa)
lfaAAlpha-glucosidase; Protein involved in hydrolase activity, hydrolyzing O-glycosyl compounds, polysaccharide catabolic process and carbohydrate metabolic process; Belongs to the glycosyl hydrolase 31 family. (791 aa)
pemBPossible pectinesterase; Probably involved in the degradation of methylated oligogalacturonides present in the periplasm. (433 aa)
pemAPectinesterase; Involved in maceration and soft-rotting of plant tissue. (366 aa)
pelIEndo-pectate lyase; PelI is secreted by the Out secretion system; Protein involved in pectate lyase activity, interaction with host via protein secreted by type II secretion system, metabolism by symbiont of substance in host, pathogenesis and pectin catabolic process. (344 aa)
pelXExopolygalacturonate lyase PelX; Protein involved in pectate lyase activity, polysaccharide catabolic process, interaction with host via protein secreted by type II secretion system, metabolism by symbiont of substance in host and pectin catabolic process. (734 aa)
pehKPolygalacturonase; Protein involved in polygalacturonase activity, catalytic activity, carbohydrate catabolic process, polysaccharide catabolic process, metabolism by symbiont of host cell wall pectin, interaction with host via protein secreted by type II secretion system and carbohydrate metabolic process; Belongs to the glycosyl hydrolase 28 family. (459 aa)
gntRDNA-binding transcriptional repressor; GlnR belongs to the lacI family of transcriptional regulators; Protein involved in transcription repressor activity, transcription factor activity, Entner-Doudoroff pathway, transcription and regulation of transcription, DNA-dependent. (332 aa)
pecTProbable HTH-type transcriptional regulator lrhA; Regulates pectinase gene expression. (316 aa)
slyADNA-binding transcriptional activator; Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family. (145 aa)
avrMAvirulence protein; Putative type III (hrp) secreted protein; probably effector; Protein involved in (DEPRECATED) molecular function unknown, metallopeptidase activity, zinc ion binding, (DEPRECATED) biological process unknown and proteolysis. (630 aa)
nipEPromoter is bound by pecS; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. (263 aa)
pecSDNA-binding transcriptional regulatory protein PecS; Negative regulator of pectinase, cellulase, blue pigment production and virulence genes. Also binds to promoter sites in the pecS-pecM intergenic region and negatively autoregulate its expression as well as that of pecM. (166 aa)
rhiERhamnogalacturonate lyase precursor; Degrades the rhamnogalacturonan I (RG-I) backbone of pectin. Is required for the full virulence of E.chrysanthemi strain 3937 as it is involved in rotting of plant tissue; Belongs to the polysaccharide lyase 4 family. (578 aa)
prtGSecreted protease C precursor; Protein involved in calcium ion binding, metallopeptidase activity, zinc ion binding, metalloendopeptidase activity, nitrogen compound metabolic process, amino acid catabolic process, modulation by symbiont of host protease activity, interaction with host via protein secreted by type II secretion system and proteolysis. (477 aa)
celYEndoglucanase Y; Represents only 3% of the global cellulase activity; Belongs to the glycosyl hydrolase 8 (cellulase D) family. (332 aa)
nagZbeta-N-acetylglucosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (341 aa)
celHBeta-glucosidase; Protein involved in hydrolase activity, hydrolyzing O-glycosyl compounds, catalytic activity, cation binding, carbohydrate catabolic process and carbohydrate metabolic process; Belongs to the glycosyl hydrolase 1 family. (478 aa)
pelLPectate lyase pelL; Presents an endo-cleaving activity on polygalacturonate or partially methylated pectin. Is effective in the maceration of plant tissue, and has an important role in soft-rot disease. Is 280-fold less active against polygalacturonate than the major pectate lyase PelB. When assayed on polygalacturonate, PelL releases oligogalacturonates of different sizes; upon prolonged incubation, PelL degrades the primary products to unsaturated tetramer and pentamer in addition to unsaturated dimer and trimer. When assayed on oligogalacturonates (degrees of polymerization of 2 to [...] (425 aa)
acsB2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Protein involved in carbon-carbon lyase activity, iron ion transport, achromobactin biosynthetic process, cellular aromatic compound metabolic process and pathogenesis; Belongs to the HpcH/HpaI aldolase family. (258 aa)
bglXPeriplasmic beta-glucosidase; Protein involved in hydrolase activity, hydrolyzing O-glycosyl compounds, carbohydrate catabolic process and carbohydrate metabolic process; Belongs to the glycosyl hydrolase 3 family. (768 aa)
hrpWType III secreted protein; HR-eliciting activity; Protein involved in pectate lyase activity, interaction with host via protein secreted by type III secretion system and pathogenesis. (569 aa)
avrLAvirulence protein; AvrL is secreted by the Out system; promoter is bound by pecS; Protein involved in metallopeptidase activity, zinc ion binding, interaction with host via protein secreted by type II secretion system and proteolysis. (618 aa)
pelWExopolygalacturonate lyase; Catalyzes the formation of unsaturated digalacturonates from polygalacturonate or short oligogalacturonates. Belongs to the polysaccharide lyase 2 family. (543 aa)
paeYPectin acetylesterase; PaeY is secreted by the Out secretion system; Protein involved in hydrolase activity, acetylesterase activity, polysaccharide catabolic process, carbohydrate catabolic process, metabolism by symbiont of host cell wall pectin, interaction with host via protein secreted by type II secretion system, pathogenesis and entry into host. (551 aa)
prtBSecreted protease B precursor; Protein involved in calcium ion binding, metallopeptidase activity, zinc ion binding, metalloendopeptidase activity, peptidase activity, modulation by symbiont of host protease activity, interaction with host via secreted substance, proteolysis and protein catabolic process. (481 aa)
pelBPectate lyase B; PelB is secreted by the Out secretion system; Protein involved in pectate lyase activity, polysaccharide catabolic process, interaction with host via protein secreted by type II secretion system, metabolism by symbiont of substance in host and pathogenesis. (375 aa)
pelCPectate lyase C; PelC is secretd by the Out secretion system; Protein involved in polysaccharide catabolic process, carbohydrate catabolic process and pathogenesis. (374 aa)
pelZPectate lyase; PelZ is secreted by the Out secretion system; Protein involved in pectate lyase activity, interaction with host via protein secreted by type II secretion system, metabolism by symbiont of substance in host, pectin catabolic process and pathogenesis. (425 aa)
pehNExo-poly-alpha-D-galacturonosidase; Protein involved in polygalacturonase activity, carbohydrate catabolic process, polysaccharide catabolic process, metabolism by symbiont of host cell wall pectin and carbohydrate metabolic process; Belongs to the glycosyl hydrolase 28 family. (467 aa)
Your Current Organism:
Dickeya dadantii
NCBI taxonomy Id: 198628
Other names: D. dadantii 3937, Dickeya dadantii 3937, Dickeya dadantii str. 3937, Dickeya dadantii strain 3937, Erwinia chrysanthemi str. 3937, Pectobacterium chrysanthemi str. 3937
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