STRINGSTRING
paeX paeX pelL pelL xynA xynA pelW pelW pelA pelA pelE pelE pelD pelD paeY paeY pemA pemA yfhD yfhD tadA tadA fliC fliC lfaA lfaA kdgR kdgR bgxA bgxA arbB arbB prtC prtC hecB hecB pehN pehN pelZ pelZ pelC pelC pelB pelB plcA plcA prtB prtB pelI pelI pelX pelX pehK pehK pehX pehX pehW pehW pldA pldA pecT pecT slyA slyA ADM97677.1 ADM97677.1 pecS pecS prtG prtG rhsA rhsA celY celY nagZ nagZ celH celH virB2 virB2 virB1 virB1 cel5Z cel5Z
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
paeXProtein involved in acetylesterase activity, metabolism by symbiont of host cell wall pectin, interaction with host via protein secreted by type II secretion system, pathogenesis and pectin catabolic process. (322 aa)
pelLPectate lyase pelL; Presents an endo-cleaving activity on polygalacturonate or partially methylated pectin. Is effective in the maceration of plant tissue, and has an important role in soft-rot disease. Is 280-fold less active against polygalacturonate than the major pectate lyase PelB. When assayed on polygalacturonate, PelL releases oligogalacturonates of different sizes; upon prolonged incubation, PelL degrades the primary products to unsaturated tetramer and pentamer in addition to unsaturated dimer and trimer. When assayed on oligogalacturonates (degrees of polymerization of 2 to [...] (425 aa)
xynAXylanase; Protein involved in catalytic activity, cation binding, glucosylceramidase activity, endo-1,4-beta-xylanase activity, carbohydrate catabolic process, glucose metabolic process, polysaccharide catabolic process, metabolism by symbiont of substance in host, carbohydrate metabolic process, sphingolipid metabolic process and lysosome organization; Belongs to the glycosyl hydrolase 30 family. (413 aa)
pelWExopolygalacturonate lyase; Catalyzes the formation of unsaturated digalacturonates from polygalacturonate or short oligogalacturonates. Belongs to the polysaccharide lyase 2 family. (543 aa)
pelAPectate lyase, Pla; Involved in maceration and soft-rotting of plant tissue. (392 aa)
pelEPectate lyase pelE; Involved in maceration and soft-rotting of plant tissue. Pectate lyases have been implicated as pathogenicity factors which induce maceration or rotting of plant tissue. PelE is sufficient to induce these effects under laboratory conditions. (404 aa)
pelDPectate lyase D; PelE is secreted by the Out secretion system; Protein involved in pectate lyase activity, polysaccharide catabolic process, carbohydrate catabolic process, interaction with host via protein secreted by type II secretion system, metabolism by symbiont of substance in host and pathogenesis. (392 aa)
paeYPectin acetylesterase; PaeY is secreted by the Out secretion system; Protein involved in hydrolase activity, acetylesterase activity, polysaccharide catabolic process, carbohydrate catabolic process, metabolism by symbiont of host cell wall pectin, interaction with host via protein secreted by type II secretion system, pathogenesis and entry into host. (551 aa)
pemAPectinesterase; Involved in maceration and soft-rotting of plant tissue. (366 aa)
yfhDLytic transglycosylase; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. (485 aa)
tadAtRNA-specific adenosine-34 deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (167 aa)
fliCFlagellar filament structural protein (flagellin); Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (280 aa)
lfaAAlpha-glucosidase; Protein involved in hydrolase activity, hydrolyzing O-glycosyl compounds, polysaccharide catabolic process and carbohydrate metabolic process; Belongs to the glycosyl hydrolase 31 family. (791 aa)
kdgRDNA-binding transcriptional regulatory protein KdgR; KdgR interacts with 2-keto-3-deoxygluconate which is an inducer; The consensus KdgR-binding site is ATRAAAYRNYRTTTYAT; KdgR belongs to the IclR family of transcriptional regulator; Protein involved in DNA binding, transcription repressor activity, metabolism by symbiont of host cell wall pectin, regulation of transcription, DNA-dependent, negative regulation of transcription and pathogenesis. (263 aa)
bgxABeta-glucosidase (Gentiobiase) (Cellobiase) / Beta- xylosidase; Protein involved in hydrolase activity, hydrolyzing O-glycosyl compounds, polysaccharide catabolic process and carbohydrate metabolic process. (671 aa)
arbBPhospho-beta-glucosidase; Protein involved in hydrolase activity, hydrolyzing O-glycosyl compounds, catalytic activity, cation binding, carbohydrate catabolic process and carbohydrate metabolic process; Belongs to the glycosyl hydrolase 1 family. (466 aa)
prtCSecreted protease C precursor; Protein involved in calcium ion binding, metallopeptidase activity, zinc ion binding, metalloendopeptidase activity, peptidase activity, modulation by symbiont of host protease activity, interaction with host via protein secreted by type II secretion system, proteolysis and protein catabolic process. (479 aa)
hecBHemolysin activator protein precursor; Probable outer membrane protein component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system. CDI modules allow bacteria to communicate with and inhibit the growth of closely related neighboring bacteria in a contact-dependent fashion. This protein may be required for secretion and assembly of the CdiA toxin; Belongs to the TPS (TC 1.B.20) family. (558 aa)
pehNExo-poly-alpha-D-galacturonosidase; Protein involved in polygalacturonase activity, carbohydrate catabolic process, polysaccharide catabolic process, metabolism by symbiont of host cell wall pectin and carbohydrate metabolic process; Belongs to the glycosyl hydrolase 28 family. (467 aa)
pelZPectate lyase; PelZ is secreted by the Out secretion system; Protein involved in pectate lyase activity, interaction with host via protein secreted by type II secretion system, metabolism by symbiont of substance in host, pectin catabolic process and pathogenesis. (425 aa)
pelCPectate lyase C; PelC is secretd by the Out secretion system; Protein involved in polysaccharide catabolic process, carbohydrate catabolic process and pathogenesis. (374 aa)
pelBPectate lyase B; PelB is secreted by the Out secretion system; Protein involved in pectate lyase activity, polysaccharide catabolic process, interaction with host via protein secreted by type II secretion system, metabolism by symbiont of substance in host and pathogenesis. (375 aa)
plcAExtracellular phospholipase C; E. coli containing D. dadantii hrp cluster is capable of secreting an exogenous effector into tobacco, eliciting a hypersensitive response; Protein involved in phospholipase A1 activity, phosphorus metabolic process, modulation of signal transduction pathway in other organism during symbiotic interaction, interaction with host via protein secreted by type III secretion system and pathogenesis. (349 aa)
prtBSecreted protease B precursor; Protein involved in calcium ion binding, metallopeptidase activity, zinc ion binding, metalloendopeptidase activity, peptidase activity, modulation by symbiont of host protease activity, interaction with host via secreted substance, proteolysis and protein catabolic process. (481 aa)
pelIEndo-pectate lyase; PelI is secreted by the Out secretion system; Protein involved in pectate lyase activity, interaction with host via protein secreted by type II secretion system, metabolism by symbiont of substance in host, pathogenesis and pectin catabolic process. (344 aa)
pelXExopolygalacturonate lyase PelX; Protein involved in pectate lyase activity, polysaccharide catabolic process, interaction with host via protein secreted by type II secretion system, metabolism by symbiont of substance in host and pectin catabolic process. (734 aa)
pehKPolygalacturonase; Protein involved in polygalacturonase activity, catalytic activity, carbohydrate catabolic process, polysaccharide catabolic process, metabolism by symbiont of host cell wall pectin, interaction with host via protein secreted by type II secretion system and carbohydrate metabolic process; Belongs to the glycosyl hydrolase 28 family. (459 aa)
pehXExo-poly-alpha-D-galacturonosidase precursor; Protein involved in polygalacturonase activity, pectate lyase activity, polysaccharide catabolic process, carbohydrate catabolic process, interaction with host via protein secreted by type II secretion system, metabolism by symbiont of substance in host, carbohydrate metabolic process, pectin catabolic process and metabolism by symbiont of host cell wall pectin; Belongs to the glycosyl hydrolase 28 family. (602 aa)
pehWPolygalacturonase; Protein involved in polygalacturonase activity, carbohydrate catabolic process, polysaccharide catabolic process, metabolism by symbiont of host cell wall pectin, interaction with host via protein secreted by type II secretion system and carbohydrate metabolic process; Belongs to the glycosyl hydrolase 28 family. (606 aa)
pldAOuter membrane phospholipase A; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family. (297 aa)
pecTProbable HTH-type transcriptional regulator lrhA; Regulates pectinase gene expression. (316 aa)
slyADNA-binding transcriptional activator; Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family. (145 aa)
ADM97677.1ImpB; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. (167 aa)
pecSDNA-binding transcriptional regulatory protein PecS; Negative regulator of pectinase, cellulase, blue pigment production and virulence genes. Also binds to promoter sites in the pecS-pecM intergenic region and negatively autoregulate its expression as well as that of pecM. (166 aa)
prtGSecreted protease C precursor; Protein involved in calcium ion binding, metallopeptidase activity, zinc ion binding, metalloendopeptidase activity, nitrogen compound metabolic process, amino acid catabolic process, modulation by symbiont of host protease activity, interaction with host via protein secreted by type II secretion system and proteolysis. (477 aa)
rhsARhs-family protein; Toxic component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system. This protein may be a nuclease that is specifically inhibited by its cognate immunity protein RhsAI. Upon expression of the C- terminus (residues 1284-1434) in E.coli growth is inhibited, cells elongate, nucleoids condense and plasmid DNA is degraded; these effects are blocked specifically by cognate immunity protein RshIA. Cell contact is necessary for growth inhibition. (1434 aa)
celYEndoglucanase Y; Represents only 3% of the global cellulase activity; Belongs to the glycosyl hydrolase 8 (cellulase D) family. (332 aa)
nagZbeta-N-acetylglucosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (341 aa)
celHBeta-glucosidase; Protein involved in hydrolase activity, hydrolyzing O-glycosyl compounds, catalytic activity, cation binding, carbohydrate catabolic process and carbohydrate metabolic process; Belongs to the glycosyl hydrolase 1 family. (478 aa)
virB2Major pilus subunit of type IV secretion complex (VirB2). (93 aa)
virB1VirB1; Bores hole in peptidoglycan layer allowing type IV secretion complex assembly to occur; Protein involved in (DEPRECATED) molecular function unknown and (DEPRECATED) biological process unknown. (228 aa)
cel5ZEndo-1,4-beta-glucanase precursor; Represents 97% of the global cellulase activity. (426 aa)
Your Current Organism:
Dickeya dadantii
NCBI taxonomy Id: 198628
Other names: D. dadantii 3937, Dickeya dadantii 3937, Dickeya dadantii str. 3937, Dickeya dadantii strain 3937, Erwinia chrysanthemi str. 3937, Pectobacterium chrysanthemi str. 3937
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.