STRINGSTRING
pelE pelE rpoN rpoN ycgR ycgR pelZ pelZ pelC pelC pelB pelB secA secA cheY cheY pelA pelA cyaA cyaA slyA slyA vfmE vfmE rpoA rpoA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pelEPectate lyase pelE; Involved in maceration and soft-rotting of plant tissue. Pectate lyases have been implicated as pathogenicity factors which induce maceration or rotting of plant tissue. PelE is sufficient to induce these effects under laboratory conditions. (404 aa)
rpoNRNA polymerase, sigma 54 (sigma N) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (477 aa)
ycgRHypothetical protein; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility. (254 aa)
pelZPectate lyase; PelZ is secreted by the Out secretion system; Protein involved in pectate lyase activity, interaction with host via protein secreted by type II secretion system, metabolism by symbiont of substance in host, pectin catabolic process and pathogenesis. (425 aa)
pelCPectate lyase C; PelC is secretd by the Out secretion system; Protein involved in polysaccharide catabolic process, carbohydrate catabolic process and pathogenesis. (374 aa)
pelBPectate lyase B; PelB is secreted by the Out secretion system; Protein involved in pectate lyase activity, polysaccharide catabolic process, interaction with host via protein secreted by type II secretion system, metabolism by symbiont of substance in host and pathogenesis. (375 aa)
secAPreprotein translocase subunit, ATPase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (895 aa)
cheYChemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY; Protein involved in two-component response regulator activity, taxis and protein modification process. (129 aa)
pelAPectate lyase, Pla; Involved in maceration and soft-rotting of plant tissue. (392 aa)
cyaAProtein involved in adenylate cyclase activity, nucleobase, nucleoside and nucleotide interconversion and cAMP biosynthetic process; Belongs to the adenylyl cyclase class-1 family. (852 aa)
slyADNA-binding transcriptional activator; Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family. (145 aa)
vfmEVfmE belongs to the AraC family of transcriptional regulators; Protein involved in transcription factor activity, sequence-specific DNA binding, DNA binding, transcription, regulation of transcription, DNA-dependent, metabolism by symbiont of substance in host, regulation of transcription and pathogenesis. (187 aa)
rpoADNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (329 aa)
Your Current Organism:
Dickeya dadantii
NCBI taxonomy Id: 198628
Other names: D. dadantii 3937, Dickeya dadantii 3937, Dickeya dadantii str. 3937, Dickeya dadantii strain 3937, Erwinia chrysanthemi str. 3937, Pectobacterium chrysanthemi str. 3937
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.