STRINGSTRING
prtC prtC pehK pehK pehX pehX pehW pehW lacZ lacZ vfmE vfmE vfmA vfmA gyrB gyrB cel5Z cel5Z pelE pelE pelD pelD rpoD rpoD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
prtCSecreted protease C precursor; Protein involved in calcium ion binding, metallopeptidase activity, zinc ion binding, metalloendopeptidase activity, peptidase activity, modulation by symbiont of host protease activity, interaction with host via protein secreted by type II secretion system, proteolysis and protein catabolic process. (479 aa)
pehKPolygalacturonase; Protein involved in polygalacturonase activity, catalytic activity, carbohydrate catabolic process, polysaccharide catabolic process, metabolism by symbiont of host cell wall pectin, interaction with host via protein secreted by type II secretion system and carbohydrate metabolic process; Belongs to the glycosyl hydrolase 28 family. (459 aa)
pehXExo-poly-alpha-D-galacturonosidase precursor; Protein involved in polygalacturonase activity, pectate lyase activity, polysaccharide catabolic process, carbohydrate catabolic process, interaction with host via protein secreted by type II secretion system, metabolism by symbiont of substance in host, carbohydrate metabolic process, pectin catabolic process and metabolism by symbiont of host cell wall pectin; Belongs to the glycosyl hydrolase 28 family. (602 aa)
pehWPolygalacturonase; Protein involved in polygalacturonase activity, carbohydrate catabolic process, polysaccharide catabolic process, metabolism by symbiont of host cell wall pectin, interaction with host via protein secreted by type II secretion system and carbohydrate metabolic process; Belongs to the glycosyl hydrolase 28 family. (606 aa)
lacZBeta-galactosidase; Protein involved in hydrolase activity, hydrolyzing O-glycosyl compounds, beta-galactosidase activity, catalytic activity, cation binding, carbohydrate catabolic process and carbohydrate metabolic process; Belongs to the glycosyl hydrolase 2 family. (1037 aa)
vfmEVfmE belongs to the AraC family of transcriptional regulators; Protein involved in transcription factor activity, sequence-specific DNA binding, DNA binding, transcription, regulation of transcription, DNA-dependent, metabolism by symbiont of substance in host, regulation of transcription and pathogenesis. (187 aa)
vfmA3-oxoacyl-[acyl-carrier-protein] synthase, KASIII. (335 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (803 aa)
cel5ZEndo-1,4-beta-glucanase precursor; Represents 97% of the global cellulase activity. (426 aa)
pelEPectate lyase pelE; Involved in maceration and soft-rotting of plant tissue. Pectate lyases have been implicated as pathogenicity factors which induce maceration or rotting of plant tissue. PelE is sufficient to induce these effects under laboratory conditions. (404 aa)
pelDPectate lyase D; PelE is secreted by the Out secretion system; Protein involved in pectate lyase activity, polysaccharide catabolic process, carbohydrate catabolic process, interaction with host via protein secreted by type II secretion system, metabolism by symbiont of substance in host and pathogenesis. (392 aa)
rpoDRNA polymerase, sigma 70 (sigma D) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (611 aa)
Your Current Organism:
Dickeya dadantii
NCBI taxonomy Id: 198628
Other names: D. dadantii 3937, Dickeya dadantii 3937, Dickeya dadantii str. 3937, Dickeya dadantii strain 3937, Erwinia chrysanthemi str. 3937, Pectobacterium chrysanthemi str. 3937
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