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ilvI ilvI ilvH ilvH ilvN ilvN ilvB ilvB ilvC ilvC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ilvIAcetolactate synthase isozyme III large subunit; Escherichia coli K-12 ortholog: b0077; Escherichia coli O157:H7 ortholog: z0087. (604 aa)
ilvHAcetolactate synthase isozyme III small subunit; Escherichia coli K-12 ortholog: b0078; Escherichia coli O157:H7 ortholog: z0088. (173 aa)
ilvNAcetolactate synthase isozyme I small subunit; Escherichia coli K-12 ortholog: b3670; Escherichia coli O157:H7 ortholog: z5164; Belongs to the acetolactate synthase small subunit family. (96 aa)
ilvBAcetolactate synthase isozyme I large subunit; Escherichia coli K-12 ortholog: b3671; Escherichia coli O157:H7 ortholog: z5165. (562 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (541 aa)
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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