6 items (Escherichia coli CFT073) - STRING interaction network

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Your Input:
	glnE	Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] (983 aa)
	ygiF	Hypothetical protein ygiF; ORFXE; Escherichia coli K-12 ortholog: b3054; Escherichia coli O157:H7 ortholog: z4407. (442 aa)
	c3803	Putative Transposase; Escherichia coli O157:H7 ortholog: z5815. (150 aa)
	ydcM	Hypothetical protein ydcM; Escherichia coli K-12 ortholog: b1432; Escherichia coli O157:H7 ortholog: z3664. (401 aa)
	ygiM	Hypothetical protein ygiM precursor; Escherichia coli K-12 ortholog: b3055; Escherichia coli O157:H7 ortholog: z4408. (206 aa)
	cca	tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. (412 aa)

Your Current Organism:

Escherichia coli CFT073

NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
c3803	glnE	c3803	c3801	Putative Transposase; Escherichia coli O157:H7 ortholog: z5815.	Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]	0.639
c3803	ydcM	c3803	c3804	Putative Transposase; Escherichia coli O157:H7 ortholog: z5815.	Hypothetical protein ydcM; Escherichia coli K-12 ortholog: b1432; Escherichia coli O157:H7 ortholog: z3664.	0.898
c3803	ygiF	c3803	c3802	Putative Transposase; Escherichia coli O157:H7 ortholog: z5815.	Hypothetical protein ygiF; ORFXE; Escherichia coli K-12 ortholog: b3054; Escherichia coli O157:H7 ortholog: z4407.	0.643
cca	ygiM	c3806	c3805	tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.	Hypothetical protein ygiM precursor; Escherichia coli K-12 ortholog: b3055; Escherichia coli O157:H7 ortholog: z4408.	0.696
glnE	c3803	c3801	c3803	Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]	Putative Transposase; Escherichia coli O157:H7 ortholog: z5815.	0.639
glnE	ydcM	c3801	c3804	Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]	Hypothetical protein ydcM; Escherichia coli K-12 ortholog: b1432; Escherichia coli O157:H7 ortholog: z3664.	0.478
glnE	ygiF	c3801	c3802	Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]	Hypothetical protein ygiF; ORFXE; Escherichia coli K-12 ortholog: b3054; Escherichia coli O157:H7 ortholog: z4407.	0.804
glnE	ygiM	c3801	c3805	Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]	Hypothetical protein ygiM precursor; Escherichia coli K-12 ortholog: b3055; Escherichia coli O157:H7 ortholog: z4408.	0.514
ydcM	c3803	c3804	c3803	Hypothetical protein ydcM; Escherichia coli K-12 ortholog: b1432; Escherichia coli O157:H7 ortholog: z3664.	Putative Transposase; Escherichia coli O157:H7 ortholog: z5815.	0.898
ydcM	glnE	c3804	c3801	Hypothetical protein ydcM; Escherichia coli K-12 ortholog: b1432; Escherichia coli O157:H7 ortholog: z3664.	Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]	0.478
ydcM	ygiF	c3804	c3802	Hypothetical protein ydcM; Escherichia coli K-12 ortholog: b1432; Escherichia coli O157:H7 ortholog: z3664.	Hypothetical protein ygiF; ORFXE; Escherichia coli K-12 ortholog: b3054; Escherichia coli O157:H7 ortholog: z4407.	0.484
ygiF	c3803	c3802	c3803	Hypothetical protein ygiF; ORFXE; Escherichia coli K-12 ortholog: b3054; Escherichia coli O157:H7 ortholog: z4407.	Putative Transposase; Escherichia coli O157:H7 ortholog: z5815.	0.643
ygiF	glnE	c3802	c3801	Hypothetical protein ygiF; ORFXE; Escherichia coli K-12 ortholog: b3054; Escherichia coli O157:H7 ortholog: z4407.	Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]	0.804
ygiF	ydcM	c3802	c3804	Hypothetical protein ygiF; ORFXE; Escherichia coli K-12 ortholog: b3054; Escherichia coli O157:H7 ortholog: z4407.	Hypothetical protein ydcM; Escherichia coli K-12 ortholog: b1432; Escherichia coli O157:H7 ortholog: z3664.	0.484
ygiM	cca	c3805	c3806	Hypothetical protein ygiM precursor; Escherichia coli K-12 ortholog: b3055; Escherichia coli O157:H7 ortholog: z4408.	tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.	0.696
ygiM	glnE	c3805	c3801	Hypothetical protein ygiM precursor; Escherichia coli K-12 ortholog: b3055; Escherichia coli O157:H7 ortholog: z4408.	Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]	0.514