node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
c4007 | cafA | c4007 | c4001 | Hypothetical protein. | Ribonuclease G; Involved in the processing of the 5'-end of 16S rRNA. Could be involved in chromosome segregation and cell division. It may be one of the components of the cytoplasmic axial filaments bundles or merely regulate the formation of this structure (By similarity). | 0.437 |
c4007 | yhdE | c4007 | c4002 | Hypothetical protein. | Maf-like protein yhdE; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.437 |
cafA | c4007 | c4001 | c4007 | Ribonuclease G; Involved in the processing of the 5'-end of 16S rRNA. Could be involved in chromosome segregation and cell division. It may be one of the components of the cytoplasmic axial filaments bundles or merely regulate the formation of this structure (By similarity). | Hypothetical protein. | 0.437 |
cafA | rph | c4001 | c4467 | Ribonuclease G; Involved in the processing of the 5'-end of 16S rRNA. Could be involved in chromosome segregation and cell division. It may be one of the components of the cytoplasmic axial filaments bundles or merely regulate the formation of this structure (By similarity). | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.499 |
cafA | tldD | c4001 | c3999 | Ribonuclease G; Involved in the processing of the 5'-end of 16S rRNA. Could be involved in chromosome segregation and cell division. It may be one of the components of the cytoplasmic axial filaments bundles or merely regulate the formation of this structure (By similarity). | TldD protein; Metalloprotease involved in CcdA degradation. Suppresses the inhibitory activity of the carbon storage regulator (CsrA) (By similarity). | 0.409 |
cafA | yhdE | c4001 | c4002 | Ribonuclease G; Involved in the processing of the 5'-end of 16S rRNA. Could be involved in chromosome segregation and cell division. It may be one of the components of the cytoplasmic axial filaments bundles or merely regulate the formation of this structure (By similarity). | Maf-like protein yhdE; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.889 |
cafA | yhdP | c4001 | c4000 | Ribonuclease G; Involved in the processing of the 5'-end of 16S rRNA. Could be involved in chromosome segregation and cell division. It may be one of the components of the cytoplasmic axial filaments bundles or merely regulate the formation of this structure (By similarity). | Hypothetical protein yhdP; Escherichia coli K-12 ortholog: b3245; Escherichia coli O157:H7 ortholog: z4604. | 0.633 |
pmbA | tldD | c5333 | c3999 | TldE protein; Escherichia coli K-12 ortholog: b4235; Escherichia coli O157:H7 ortholog: z5845. | TldD protein; Metalloprotease involved in CcdA degradation. Suppresses the inhibitory activity of the carbon storage regulator (CsrA) (By similarity). | 0.910 |
pmbA | ybiM | c5333 | c0891 | TldE protein; Escherichia coli K-12 ortholog: b4235; Escherichia coli O157:H7 ortholog: z5845. | Hypothetical protein ybiM; Escherichia coli K-12 ortholog: b0806; Escherichia coli O157:H7 ortholog: z1027. | 0.680 |
rph | cafA | c4467 | c4001 | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | Ribonuclease G; Involved in the processing of the 5'-end of 16S rRNA. Could be involved in chromosome segregation and cell division. It may be one of the components of the cytoplasmic axial filaments bundles or merely regulate the formation of this structure (By similarity). | 0.499 |
rph | yggV | c4467 | c3540 | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | HAM1 protein homolog; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.962 |
tldD | cafA | c3999 | c4001 | TldD protein; Metalloprotease involved in CcdA degradation. Suppresses the inhibitory activity of the carbon storage regulator (CsrA) (By similarity). | Ribonuclease G; Involved in the processing of the 5'-end of 16S rRNA. Could be involved in chromosome segregation and cell division. It may be one of the components of the cytoplasmic axial filaments bundles or merely regulate the formation of this structure (By similarity). | 0.409 |
tldD | pmbA | c3999 | c5333 | TldD protein; Metalloprotease involved in CcdA degradation. Suppresses the inhibitory activity of the carbon storage regulator (CsrA) (By similarity). | TldE protein; Escherichia coli K-12 ortholog: b4235; Escherichia coli O157:H7 ortholog: z5845. | 0.910 |
tldD | yhdE | c3999 | c4002 | TldD protein; Metalloprotease involved in CcdA degradation. Suppresses the inhibitory activity of the carbon storage regulator (CsrA) (By similarity). | Maf-like protein yhdE; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.451 |
tldD | yhdP | c3999 | c4000 | TldD protein; Metalloprotease involved in CcdA degradation. Suppresses the inhibitory activity of the carbon storage regulator (CsrA) (By similarity). | Hypothetical protein yhdP; Escherichia coli K-12 ortholog: b3245; Escherichia coli O157:H7 ortholog: z4604. | 0.571 |
ybiM | pmbA | c0891 | c5333 | Hypothetical protein ybiM; Escherichia coli K-12 ortholog: b0806; Escherichia coli O157:H7 ortholog: z1027. | TldE protein; Escherichia coli K-12 ortholog: b4235; Escherichia coli O157:H7 ortholog: z5845. | 0.680 |
yfiH | yggS | c3115 | c3537 | Hypothetical protein yfiH; Escherichia coli K-12 ortholog: b2593; Escherichia coli O157:H7 ortholog: z3887; Belongs to the multicopper oxidase YfiH/RL5 family. | Hypothetical protein yggS; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.774 |
yggR | yggS | c3536 | c3537 | Hypothetical protein yggR; Escherichia coli K-12 ortholog: b2950; Escherichia coli O157:H7 ortholog: z4295. | Hypothetical protein yggS; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.627 |
yggR | yggT | c3536 | c3538 | Hypothetical protein yggR; Escherichia coli K-12 ortholog: b2950; Escherichia coli O157:H7 ortholog: z4295. | Hypothetical protein yggT; Escherichia coli K-12 ortholog: b2952; Escherichia coli O157:H7 ortholog: z4297. | 0.597 |
yggR | yggU | c3536 | c3539 | Hypothetical protein yggR; Escherichia coli K-12 ortholog: b2950; Escherichia coli O157:H7 ortholog: z4295. | Hypothetical protein yggU; Escherichia coli K-12 ortholog: b2953; Escherichia coli O157:H7 ortholog: z4298; Belongs to the UPF0235 family. | 0.597 |