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ybiM ybiM yfiH yfiH yggR yggR yggS yggS yggT yggT yggU yggU yggV yggV yggW yggW tldD tldD yhdP yhdP cafA cafA yhdE yhdE c4007 c4007 rph rph pmbA pmbA yjjX yjjX
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ybiMHypothetical protein ybiM; Escherichia coli K-12 ortholog: b0806; Escherichia coli O157:H7 ortholog: z1027. (134 aa)
yfiHHypothetical protein yfiH; Escherichia coli K-12 ortholog: b2593; Escherichia coli O157:H7 ortholog: z3887; Belongs to the multicopper oxidase YfiH/RL5 family. (243 aa)
yggRHypothetical protein yggR; Escherichia coli K-12 ortholog: b2950; Escherichia coli O157:H7 ortholog: z4295. (351 aa)
yggSHypothetical protein yggS; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (234 aa)
yggTHypothetical protein yggT; Escherichia coli K-12 ortholog: b2952; Escherichia coli O157:H7 ortholog: z4297. (188 aa)
yggUHypothetical protein yggU; Escherichia coli K-12 ortholog: b2953; Escherichia coli O157:H7 ortholog: z4298; Belongs to the UPF0235 family. (100 aa)
yggVHAM1 protein homolog; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (197 aa)
yggWHypothetical protein yggW; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (378 aa)
tldDTldD protein; Metalloprotease involved in CcdA degradation. Suppresses the inhibitory activity of the carbon storage regulator (CsrA) (By similarity). (481 aa)
yhdPHypothetical protein yhdP; Escherichia coli K-12 ortholog: b3245; Escherichia coli O157:H7 ortholog: z4604. (1266 aa)
cafARibonuclease G; Involved in the processing of the 5'-end of 16S rRNA. Could be involved in chromosome segregation and cell division. It may be one of the components of the cytoplasmic axial filaments bundles or merely regulate the formation of this structure (By similarity). (495 aa)
yhdEMaf-like protein yhdE; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (197 aa)
c4007Hypothetical protein. (62 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (246 aa)
pmbATldE protein; Escherichia coli K-12 ortholog: b4235; Escherichia coli O157:H7 ortholog: z5845. (450 aa)
yjjXHypothetical protein yjjX; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. (178 aa)
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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