STRINGSTRING
aroP aroP dcuC dcuC ydiI ydiI tyrP tyrP menE menE menC menC menB menB yfbB yfbB menD menD menF menF yqfB yqfB mtr mtr c3915 c3915 menA menA dcuB dcuB yjjB yjjB yjjP yjjP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
aroPAromatic amino acid transport protein aroP; Permease that is involved in the transport across the cytoplasmic membrane of the aromatic amino acids (phenylalanine, tyrosine, and tryptophan); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. (456 aa)
dcuCAnaerobic C4-dicarboxylate transporter dcuC; Responsible for the transport of C4-dicarboxylates during anaerobic growth; Belongs to the DcuC/DcuD transporter (TC 2.A.61) family. (461 aa)
ydiIHypothetical protein ydiI; Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA). (136 aa)
tyrPTyrosine-specific transport protein; Tyrosine permease; Escherichia coli K-12 ortholog: b1907; Escherichia coli O157:H7 ortholog: z2963. (403 aa)
menEO-succinylbenzoic acid--CoA ligase; Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA); Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily. (451 aa)
menCO-succinylbenzoate-CoA synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (320 aa)
menBNaphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). (285 aa)
yfbBHypothetical protein yfbB; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). (252 aa)
menDMenaquinone biosynthesis protein menD; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). (619 aa)
menFMenaquinone-specific isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. (431 aa)
yqfBHypothetical protein yqfB; Escherichia coli K-12 ortholog: b2900; Escherichia coli O157:H7 ortholog: z4238; Belongs to the UPF0267 family. (103 aa)
mtrTryptophan-specific transport protein; Tryptophan permease; Escherichia coli K-12 ortholog: b3161; Escherichia coli O157:H7 ortholog: z4522. (414 aa)
c3915Hypothetical protein. (45 aa)
menA1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (312 aa)
dcuBAnaerobic C4-dicarboxylate transporter dcuB; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. (446 aa)
yjjBProtein P-14; Escherichia coli K-12 ortholog: b4363; Escherichia coli O157:H7 ortholog: z5963. (162 aa)
yjjPHypothetical protein yjjP; Escherichia coli K-12 ortholog: b4364; Escherichia coli O157:H7 ortholog: z5964. (277 aa)
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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