Your Input: | |||||
| glnD | [Protein-PII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. (890 aa) | ||||
| cutF | Copper homeostasis protein cutF precursor; Lipoprotein nlpE; Escherichia coli K-12 ortholog: b0192; Escherichia coli O157:H7 ortholog: z0204. (236 aa) | ||||
| fhiA | FhiA protein; Escherichia coli K-12 ortholog: b0229; Escherichia coli O157:H7 ortholog: z0290. (579 aa) | ||||
| mbhA | MbhA protein; Escherichia coli K-12 ortholog: b0230; Escherichia coli O157:H7 ortholog: z0291. (262 aa) | ||||
| c0435 | Hypothetical protein yahA; Escherichia coli K-12 ortholog: b0315; Escherichia coli O157:H7 ortholog: z0403. (364 aa) | ||||
| prpR | Propionate catabolism operon Regulatory protein; Escherichia coli K-12 ortholog: b0330; Escherichia coli O157:H7 ortholog: z0426. (528 aa) | ||||
| yaiC | Hypothetical protein yaiC; A probable diguanylate cyclase. (371 aa) | ||||
| glnK | Nitrogen Regulatory protein P-II 2; P-II indirectly controls the transcription of the glutamine synthetase gene (GlnA). P-II prevents NR-II-catalyzed conversion of NR- I to NR-I-phosphate, the transcriptional activator of GlnA. When P-II is uridylylated to P-II-UMP, these events are reversed. When the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylation of glutamine synthetase by GlnE, so activating the enzyme (By similarity); Belongs to the P(II) protein family. (112 aa) | ||||
| amtB | Probable ammonium transporter; Escherichia coli K-12 ortholog: b0451; Escherichia coli O157:H7 ortholog: z0563. (428 aa) | ||||
| ylaB | Hypothetical protein ylaB; Escherichia coli K-12 ortholog: b0457; Escherichia coli O157:H7 ortholog: z0569. (518 aa) | ||||
| yliE | Hypothetical protein yliE; Escherichia coli K-12 ortholog: b0833; Escherichia coli O157:H7 ortholog: z1057. (782 aa) | ||||
| yliF | Hypothetical membrane protein yliF; Escherichia coli K-12 ortholog: b0834; Escherichia coli O157:H7 ortholog: z1058. (442 aa) | ||||
| torS | Sensor protein torS; Escherichia coli K-12 ortholog: b0993; Escherichia coli O157:H7 ortholog: z1410. (576 aa) | ||||
| torT | Periplasmic protein torT precursor; Escherichia coli K-12 ortholog: b0994; Escherichia coli O157:H7 ortholog: z1411. (342 aa) | ||||
| torR | TorCAD operon transcriptional Regulatory protein torR; Escherichia coli K-12 ortholog: b0995; Escherichia coli O157:H7 ortholog: z1412. (230 aa) | ||||
| ycdT | Hypothetical protein ycdT; Escherichia coli K-12 ortholog: b1025; Escherichia coli O157:H7 ortholog: z1527. (496 aa) | ||||
| c1246 | Hypothetical protein; Residues 21 to 238 of 246 are 27.35 pct identical to residues 12 to 226 of 232 from GenPept.129 : >emb|CAC93018.1| (AJ414153) conserved hypothetical protein [Yersinia pestis]. (246 aa) | ||||
| focX | Putative Regulatory protein; Residues 18 to 183 of 183 are 100.00 pct identical to residues 1 to 166 of 166 from SwissProt.40 : >sp|P42192|PRSX_ECOLI PRSX PROTEIN. (183 aa) | ||||
| flgN | Flagella synthesis protein flgN; Escherichia coli K-12 ortholog: b1070; Escherichia coli O157:H7 ortholog: z1708. (138 aa) | ||||
| flgM | Negative regulator of flagellin synthesis; Anti-sigma-28 factor; Escherichia coli K-12 ortholog: b1071; Escherichia coli O157:H7 ortholog: z1709. (97 aa) | ||||
| flgA | Flagella basal body P-ring formation protein flgA precursor; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family. (219 aa) | ||||
| flgB | Flagellar basal-body rod protein flgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity). (138 aa) | ||||
| flgC | Flagellar basal-body rod protein flgC; Putative proximal rod protein; Escherichia coli K-12 ortholog: b1074; Escherichia coli O157:H7 ortholog: z1712; Belongs to the flagella basal body rod proteins family. (134 aa) | ||||
| flgD | Basal-body rod modification protein flgD; Required for flagellar hook formation. May act as a scaffolding protein. (231 aa) | ||||
| flgE | Flagellar hook protein flgE; Escherichia coli K-12 ortholog: b1076; Escherichia coli O157:H7 ortholog: z1714. (401 aa) | ||||
| flgF | Flagellar basal-body rod protein flgF; Putative proximal rod protein; Escherichia coli K-12 ortholog: b1077; Escherichia coli O157:H7 ortholog: z1715. (251 aa) | ||||
| flgG | Flagellar basal-body rod protein flgG; Distal rod protein; Escherichia coli K-12 ortholog: b1078; Escherichia coli O157:H7 ortholog: z1716; Belongs to the flagella basal body rod proteins family. (260 aa) | ||||
| flgH | Flagellar L-ring protein precursor; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation. (237 aa) | ||||
| flgI | Flagellar P-ring protein precursor; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation. (366 aa) | ||||
| flgJ | Peptidoglycan hydrolase flgJ; Escherichia coli K-12 ortholog: b1081; Escherichia coli O157:H7 ortholog: z1719. (323 aa) | ||||
| flgK | Flagellar hook-associated protein 1; HAP1; Escherichia coli K-12 ortholog: b1082; Escherichia coli O157:H7 ortholog: z1720. (547 aa) | ||||
| flgL | Flagellar hook-associated protein 3; HAP3; Escherichia coli K-12 ortholog: b1083; Escherichia coli O157:H7 ortholog: z1721. (317 aa) | ||||
| ycgX | Hypothetical protein ycgX; Escherichia coli K-12 ortholog: b1161; Escherichia coli O157:H7 ortholog: z1879. (134 aa) | ||||
| ycgE | Hypothetical transcriptional regulator ycgE; Escherichia coli K-12 ortholog: b1162; Escherichia coli O157:H7 ortholog: z3376. (243 aa) | ||||
| c1605 | Hypothetical protein. (50 aa) | ||||
| ycgF | Hypothetical protein ycgF; Escherichia coli K-12 ortholog: b1163. (429 aa) | ||||
| ycgZ | Hypothetical protein ycgZ; Escherichia coli K-12 ortholog: b1164. (78 aa) | ||||
| c1608 | Hypothetical protein. (57 aa) | ||||
| ymgB | Hypothetical protein ymgB; Regulates expression of genes involved in acid-resistance and biofilm formation. May be a non-specific DNA-binding protein that binds genes and/or intergenic regions via a geometric recognition (By similarity); Belongs to the AriR family. (88 aa) | ||||
| c1610 | Conserved hypothetical protein; Escherichia coli O157:H7 ortholog: z0403. (283 aa) | ||||
| ycgR | Hypothetical protein ycgR; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility. (244 aa) | ||||
| narL | Nitrate/nitrite response regulator protein narL; This protein activates the expression of the nitrate reductase (narGHJI) and formate dehydrogenase-N (fdnGHI) operons and represses the transcription of the fumarate reductase (frdABCD) operon in response to a nitrate/nitrite induction signal transmitted by either the NarX or NarQ proteins. (238 aa) | ||||
| narX | Nitrate/nitrite sensor protein narX; Escherichia coli K-12 ortholog: b1222; Escherichia coli O157:H7 ortholog: z1998. (598 aa) | ||||
| yciR | Hypothetical protein yciR; Escherichia coli K-12 ortholog: b1285; Escherichia coli O157:H7 ortholog: z2516. (661 aa) | ||||
| pspF | Psp operon transcriptional activator; Escherichia coli K-12 ortholog: b1303; Escherichia coli O157:H7 ortholog: z2484. (330 aa) | ||||
| ydaM | Hypothetical protein ydaM; Escherichia coli K-12 ortholog: b1341; Escherichia coli O157:H7 ortholog: z2421. (430 aa) | ||||
| cybB | Cytochrome b-561; Escherichia coli K-12 ortholog: b1418; Escherichia coli O157:H7 ortholog: z2303. (188 aa) | ||||
| ydcA | Hypothetical protein ydcA precursor; Escherichia coli K-12 ortholog: b1419; Escherichia coli O157:H7 ortholog: z2302. (57 aa) | ||||
| c1846 | Putative conserved protein; Residues 10 to 156 of 156 are 95.91 pct identical to residues 400 to 546 of 546 from MG1655 : b1421. (156 aa) | ||||
| bdm | Bdm protein; Biofilm-dependent modulation protein; Escherichia coli K-12 ortholog: b1481; Escherichia coli O157:H7 ortholog: z2229. (92 aa) | ||||
| c1915 | Hypothetical protein. (46 aa) | ||||
| c1918 | Putative sensor kinase; Escherichia coli O157:H7 ortholog: z2220. (446 aa) | ||||
| yneF | Hypothetical protein yneF; Escherichia coli K-12 ortholog: b1522; Escherichia coli O157:H7 ortholog: z2182. (472 aa) | ||||
| ydeH | Hypothetical protein ydeH; Escherichia coli K-12 ortholog: b1535; Escherichia coli O157:H7 ortholog: z2163. (298 aa) | ||||
| rstA | Transcriptional Regulatory protein rstA; Escherichia coli K-12 ortholog: b1608; Escherichia coli O157:H7 ortholog: z2609. (259 aa) | ||||
| rstB | Sensor protein rstB; Escherichia coli K-12 ortholog: b1609; Escherichia coli O157:H7 ortholog: z2610. (433 aa) | ||||
| ydiV | Hypothetical protein ydiV; Escherichia coli K-12 ortholog: b1707; Escherichia coli O157:H7 ortholog: z2736. (237 aa) | ||||
| yeaI | Hypothetical protein yeaI; Escherichia coli K-12 ortholog: b1785; Escherichia coli O157:H7 ortholog: z2825. (491 aa) | ||||
| yeaJ | Hypothetical protein yeaJ; Escherichia coli K-12 ortholog: b1786; Escherichia coli O157:H7 ortholog: z2826. (556 aa) | ||||
| yeaP | Hypothetical protein yeaP; Escherichia coli K-12 ortholog: b1794; Escherichia coli O157:H7 ortholog: z2836. (384 aa) | ||||
| yoaD | Hypothetical protein yoaD; Escherichia coli K-12 ortholog: b1815; Escherichia coli O157:H7 ortholog: z2858. (542 aa) | ||||
| flhA | Flagellar biosynthesis protein flhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. (717 aa) | ||||
| flhB | Flagellar biosynthetic protein flhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family. (382 aa) | ||||
| cheZ | Chemotaxis protein cheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P). (224 aa) | ||||
| cheY | Chemotaxis protein cheY; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation (By similarity). (129 aa) | ||||
| cheB | Protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (349 aa) | ||||
| cheR | Chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. (286 aa) | ||||
| c2300 | Hypothetical protein; Residues 2 to 34 of 40 are 93.93 pct identical to residues 1 to 33 of 535 from GenPept.129 : >gb|AAA23567.1| (M13463) sensory transducer protein [Escherichia coli]. (40 aa) | ||||
| tar | Methyl-accepting chemotaxis protein II; MCP-II; Escherichia coli K-12 ortholog: b1886; Escherichia coli O157:H7 ortholog: z2940. (560 aa) | ||||
| cheW | Chemotaxis protein cheW; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB (By similarity). (167 aa) | ||||
| cheA | Chemotaxis protein cheA; Escherichia coli K-12 ortholog: b1888; Escherichia coli O157:H7 ortholog: z2942. (672 aa) | ||||
| motB | Chemotaxis motB protein; Motility protein B; Escherichia coli K-12 ortholog: b1889; Escherichia coli O157:H7 ortholog: z2943. (308 aa) | ||||
| motA | Chemotaxis motA protein; Motility protein A; Escherichia coli K-12 ortholog: b1890; Escherichia coli O157:H7 ortholog: z2944. (295 aa) | ||||
| flhC | Flagellar transcriptional activator flhC; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family. (192 aa) | ||||
| flhD | Flagellar transcriptional activator flhD; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family. (119 aa) | ||||
| uvrY | UvrY protein; Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. UvrY activates the transcription of the untranslated csrB RNA and of barA, in an autoregulatory loop. Mediates the effects of CsrA on csrB RNA by BarA-dependent and BarA-independent mechanisms (By similarity). (218 aa) | ||||
| sdiA | Regulatory protein sdiA; Escherichia coli K-12 ortholog: b1916; Escherichia coli O157:H7 ortholog: z3004. (244 aa) | ||||
| fliZ | FliZ protein; Escherichia coli K-12 ortholog: b1921; Escherichia coli O157:H7 ortholog: z3011. (195 aa) | ||||
| fliA | RNA polymerase sigma factor for flagellar operon; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (239 aa) | ||||
| fliC | Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (595 aa) | ||||
| fliD | Flagellar hook-associated protein 2; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. (468 aa) | ||||
| fliS | Flagellar protein fliS; Escherichia coli K-12 ortholog: b1925; Escherichia coli O157:H7 ortholog: z3015. (136 aa) | ||||
| fliE | Flagellar hook-basal body complex protein fliE; Escherichia coli K-12 ortholog: b1937; Escherichia coli O157:H7 ortholog: z3027. (114 aa) | ||||
| fliF | Flagellar M-ring protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family. (552 aa) | ||||
| fliG | Flagellar motor switch protein fliG; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity). (331 aa) | ||||
| c2356 | Hypothetical protein. (309 aa) | ||||
| fliH | Flagellar assembly protein fliH; Escherichia coli K-12 ortholog: b1940; Escherichia coli O157:H7 ortholog: z3030. (235 aa) | ||||
| fliI | Flagellum-specific ATP synthase; Escherichia coli K-12 ortholog: b1941; Escherichia coli O157:H7 ortholog: z3031. (457 aa) | ||||
| fliJ | Flagellar fliJ protein; Flagellar protein that affects chemotactic events. Belongs to the FliJ family. (147 aa) | ||||
| fliK | Flagellar hook-length control protein; Escherichia coli K-12 ortholog: b1943; Escherichia coli O157:H7 ortholog: z3033. (375 aa) | ||||
| fliL | Flagellar fliL protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family. (154 aa) | ||||
| fliM | Flagellar motor switch protein fliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. (349 aa) | ||||
| fliN | Flagellar motor switch protein fliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family. (137 aa) | ||||
| fliO | Flagellar protein fliO; Escherichia coli K-12 ortholog: b1947; Escherichia coli O157:H7 ortholog: z3037. (122 aa) | ||||
| fliP | Flagellar biosynthetic protein fliP precursor; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. (245 aa) | ||||
| fliQ | Flagellar biosynthetic protein fliQ; Required for the assembly of the rivet at the earliest stage of flagellar biosynthesis; Belongs to the FliQ/MopD/SpaQ family. (89 aa) | ||||
| fliR | Flagellar biosynthetic protein fliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family. (261 aa) | ||||
| yedQ | Hypothetical protein yedQ; Catalyzes the synthesis of cyclic-di-GMP (c-di-GMP) via the condensation of 2 GTP molecules (By similarity). Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria. Involved in the regulation of cellulose production (By similarity). (569 aa) | ||||
| yedV | Putative sensor-like histidine kinase yedV; Member of a two-component regulatory system. (452 aa) | ||||
| yedW | Probable transcriptional Regulatory protein yedW; Escherichia coli K-12 ortholog: b1969; Escherichia coli O157:H7 ortholog: z3061. (260 aa) | ||||
| nac | Nitrogen assimilation control protein; Escherichia coli K-12 ortholog: b1988; Escherichia coli O157:H7 ortholog: z3147; Belongs to the LysR transcriptional regulatory family. (315 aa) | ||||
| yegE | Hypothetical protein yegE; Escherichia coli K-12 ortholog: b2067; Escherichia coli O157:H7 ortholog: z3236. (1105 aa) | ||||
| yehV | MerR-like regulator A; Escherichia coli K-12 ortholog: b2127; Escherichia coli O157:H7 ortholog: z3376. (243 aa) | ||||
| narP | Nitrate/nitrite response regulator protein narP; Escherichia coli K-12 ortholog: b2193; Escherichia coli O157:H7 ortholog: z3450. (225 aa) | ||||
| atoS | Sensor protein atoS; Escherichia coli K-12 ortholog: b2219. (612 aa) | ||||
| atoC | Acetoacetate metabolism Regulatory protein atoC; Ornithine/arginine decarboxylase inhibitor; Escherichia coli K-12 ortholog: b2220; Escherichia coli O157:H7 ortholog: z5580. (461 aa) | ||||
| evgA | Positive transcription regulator evgA; Member of the two-component regulatory system EvgS/EvgA. Regulates the expression of emrKY operon and yfdX. Seems also to control expression of at least one other multidrug efflux operon (By similarity). (204 aa) | ||||
| evgS | Sensor protein evgS precursor; Escherichia coli K-12 ortholog: b2370; Escherichia coli O157:H7 ortholog: z3632. (1197 aa) | ||||
| yfeA | Hypothetical protein yfeA; Escherichia coli K-12 ortholog: b2395; Escherichia coli O157:H7 ortholog: z3660. (749 aa) | ||||
| narQ | Nitrate/nitrite sensor protein narQ; Escherichia coli K-12 ortholog: b2469; Escherichia coli O157:H7 ortholog: z3726. (571 aa) | ||||
| yfgF | Hypothetical protein yfgF; Escherichia coli K-12 ortholog: b2503; Escherichia coli O157:H7 ortholog: z3766. (747 aa) | ||||
| glnB | Nitrogen Regulatory protein P-II 1; P-II indirectly controls the transcription of the glutamine synthetase gene (GlnA). P-II prevents NR-II-catalyzed conversion of NR- I to NR-I-phosphate, the transcriptional activator of GlnA. When P-II is uridylylated to P-II-UMP, these events are reversed. When the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylation of glutamine synthetase by GlnE, so activating the enzyme (By similarity). (112 aa) | ||||
| yfhA | Hypothetical protein yfHa; ORF-2; Escherichia coli K-12 ortholog: b2554; Escherichia coli O157:H7 ortholog: z3830. (457 aa) | ||||
| yfhG | Hypothetical protein yfhG; Escherichia coli K-12 ortholog: b2555; Escherichia coli O157:H7 ortholog: z3831. (239 aa) | ||||
| yfhK | Putative sensor-like histidine kinase yfhK; Escherichia coli K-12 ortholog: b2556; Escherichia coli O157:H7 ortholog: z3833. (496 aa) | ||||
| yfiL | Hypothetical protein yfiL; URF2; Escherichia coli K-12 ortholog: b2602; Escherichia coli O157:H7 ortholog: z3895. (127 aa) | ||||
| yfiR | Hypothetical protein yfiR precursor; Escherichia coli K-12 ortholog: b2603; Escherichia coli O157:H7 ortholog: z3897. (172 aa) | ||||
| yfiN | Hypothetical protein yfiN; Escherichia coli K-12 ortholog: b2604; Escherichia coli O157:H7 ortholog: z3898. (408 aa) | ||||
| yfiB | Putative lipoprotein yfiB precursor; Escherichia coli K-12 ortholog: b2605; Escherichia coli O157:H7 ortholog: z3899. (160 aa) | ||||
| csrA | Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). (61 aa) | ||||
| barA | Sensor protein barA; Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. Phosphorylates UvrY, probably via a four-step phosphorelay (By similarity). (918 aa) | ||||
| ygeV | Hypothetical sigma-54-dependent transcriptional regulator ygeV; Escherichia coli K-12 ortholog: b2869; Escherichia coli O157:H7 ortholog: z4208. (592 aa) | ||||
| ygiV | Hypothetical protein ygiV; Escherichia coli K-12 ortholog: b3023; Escherichia coli O157:H7 ortholog: z4375. (160 aa) | ||||
| ygiW | Protein ygiW precursor; Escherichia coli K-12 ortholog: b3024; Escherichia coli O157:H7 ortholog: z4376. (149 aa) | ||||
| ygiX | Transcriptional Regulatory protein qseB; Escherichia coli K-12 ortholog: b3025; Escherichia coli O157:H7 ortholog: z4377. (219 aa) | ||||
| ygiY | Sensor protein qseC; Escherichia coli K-12 ortholog: b3026; Escherichia coli O157:H7 ortholog: z4378. (449 aa) | ||||
| aer | Aerotaxis receptor; Escherichia coli K-12 ortholog: b3072; Escherichia coli O157:H7 ortholog: z4425. (506 aa) | ||||
| rpoN | RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (477 aa) | ||||
| arcB | Aerobic respiration control sensor protein arcB; Escherichia coli K-12 ortholog: b3210; Escherichia coli O157:H7 ortholog: z4574. (778 aa) | ||||
| yhdA | Hypothetical protein yhdA; Escherichia coli K-12 ortholog: b3252; Escherichia coli O157:H7 ortholog: z4611. (646 aa) | ||||
| envZ | Osmolarity sensor protein envZ; Escherichia coli K-12 ortholog: b3404; Escherichia coli O157:H7 ortholog: z4759. (450 aa) | ||||
| ompR | Transcriptional Regulatory protein ompR; Member of the two-component regulatory system EnvZ/OmpR involved in osmoregulation (particularly of genes ompF and ompC) as well as other genes. Plays a central role in both acid and osmotic stress responses. Binds to the promoter of both ompC and ompF; at low osmolarity it activates ompF transcription, while at high osmolarity it represses ompF and activates ompC transcription. (239 aa) | ||||
| yhjB | Hypothetical transcriptional regulator yhjB; Escherichia coli K-12 ortholog: b3520; Escherichia coli O157:H7 ortholog: z4933. (200 aa) | ||||
| yhjH | Hypothetical protein yhjH; Escherichia coli K-12 ortholog: b3525; Escherichia coli O157:H7 ortholog: z4939. (256 aa) | ||||
| yhjK | Protein yhjK; Escherichia coli K-12 ortholog: b3529; Escherichia coli O157:H7 ortholog: z4943. (662 aa) | ||||
| c4581 | Hypothetical protein. (165 aa) | ||||
| glnG | Nitrogen regulation protein NR(I); Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (489 aa) | ||||
| glnL | Nitrogen regulation protein NR(II); Escherichia coli K-12 ortholog: b3869; Escherichia coli O157:H7 ortholog: z5405. (349 aa) | ||||
| cpxA | Sensor protein cpxA; This protein is involved in several diverse cellular processes, such as the functioning of acetohydroxyacid synthetase I, in the biosynthesis of isoleucine and valine, the TraJ protein activation activity for tra gene expression in F plasmid, and the synthesis, translocation, or stability of cell envelope proteins. Activates CpxR by phosphorylation (By similarity). (457 aa) | ||||
| cpxR | Transcriptional Regulatory protein cpxR; Escherichia coli K-12 ortholog: b3912; Escherichia coli O157:H7 ortholog: z5457. (232 aa) | ||||
| cpxP | Conserved hypothetical protein; Acts as an accessory protein in the Cpx two-component envelope stress response system. Binds the periplasmic domain of sensor histidine kinase CpxA, inhibiting induction of the envelope stress response in the absence of inducer. Aids in combating extracytoplasmic protein-mediated toxicity. (167 aa) | ||||
| c5040 | Putative c4-dicarboxylate transport transcriptional Regulatory protein; Residues 10 to 441 of 452 are 51.61 pct identical to residues 7 to 439 of 448 from SwissProt.40 : >sp|P10046|DCTD_RHILE C4-DICARBOXYLATE TRANSPORT TRANSCRIPTIONAL REGULATORY PROTEIN DCTD. (452 aa) | ||||
| c5041 | Putative transport sensor protein; Residues 20 to 591 of 606 are 31.81 pct identical to residues 28 to 612 of 633 from GenPept.129 : >gb|AAG04725.1|AE004563_2 (AE004563) probable two-component sensor [Pseudomonas aeruginosa]. (606 aa) | ||||
| c5043 | Hypothetical protein. (46 aa) | ||||
| c5044 | Hypothetical protein. (50 aa) | ||||
| yjbQ | Hypothetical protein yjbQ; Escherichia coli K-12 ortholog: b4056; Escherichia coli O157:H7 ortholog: z5655. (138 aa) | ||||
| yjbR | Protein yjbR; Escherichia coli K-12 ortholog: b4057; Escherichia coli O157:H7 ortholog: z5656. (118 aa) | ||||
| yjcC | Hypothetical protein yjcC; Escherichia coli K-12 ortholog: b4061; Escherichia coli O157:H7 ortholog: z5660. (520 aa) | ||||
| tsr | Methyl-accepting chemotaxis protein I; MCP-I; Escherichia coli K-12 ortholog: b4355; Escherichia coli O157:H7 ortholog: z5955. (554 aa) | ||||
| rob | Right origin-binding protein; Escherichia coli K-12 ortholog: b4396; Escherichia coli O157:H7 ortholog: z5999. (289 aa) | ||||
| creA | CreA protein; Escherichia coli K-12 ortholog: b4397; Escherichia coli O157:H7 ortholog: z6000. (157 aa) | ||||
| creB | Transcriptional Regulatory protein creB; Escherichia coli K-12 ortholog: b4398; Escherichia coli O157:H7 ortholog: z6001. (229 aa) | ||||
| creC | Sensor protein creC; Escherichia coli K-12 ortholog: b4399; Escherichia coli O157:H7 ortholog: z6002. (474 aa) | ||||
| creD | Inner membrane protein creD; Escherichia coli K-12 ortholog: b4400; Escherichia coli O157:H7 ortholog: z6003. (450 aa) | ||||
| arcA | Aerobic respiration control protein arcA; Member of the two-component regulatory system ArcB/ArcA. Represses a wide variety of aerobic enzymes under anaerobic conditions. It also may be involved in the osmoregulation of envelope proteins. When activated by ArcB, it negatively regulates the expression of genes of aerobic function. Activates the transcription of the plfB operon by binding to its promoter (By similarity). (238 aa) | ||||