node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
arcA | arcB | c5488 | c3970 | Aerobic respiration control protein arcA; Member of the two-component regulatory system ArcB/ArcA. Represses a wide variety of aerobic enzymes under anaerobic conditions. It also may be involved in the osmoregulation of envelope proteins. When activated by ArcB, it negatively regulates the expression of genes of aerobic function. Activates the transcription of the plfB operon by binding to its promoter (By similarity). | Aerobic respiration control sensor protein arcB; Escherichia coli K-12 ortholog: b3210; Escherichia coli O157:H7 ortholog: z4574. | 0.995 |
arcA | envZ | c5488 | c4180 | Aerobic respiration control protein arcA; Member of the two-component regulatory system ArcB/ArcA. Represses a wide variety of aerobic enzymes under anaerobic conditions. It also may be involved in the osmoregulation of envelope proteins. When activated by ArcB, it negatively regulates the expression of genes of aerobic function. Activates the transcription of the plfB operon by binding to its promoter (By similarity). | Osmolarity sensor protein envZ; Escherichia coli K-12 ortholog: b3404; Escherichia coli O157:H7 ortholog: z4759. | 0.796 |
arcA | rstB | c5488 | c2001 | Aerobic respiration control protein arcA; Member of the two-component regulatory system ArcB/ArcA. Represses a wide variety of aerobic enzymes under anaerobic conditions. It also may be involved in the osmoregulation of envelope proteins. When activated by ArcB, it negatively regulates the expression of genes of aerobic function. Activates the transcription of the plfB operon by binding to its promoter (By similarity). | Sensor protein rstB; Escherichia coli K-12 ortholog: b1609; Escherichia coli O157:H7 ortholog: z2610. | 0.548 |
arcA | torS | c5488 | c1128 | Aerobic respiration control protein arcA; Member of the two-component regulatory system ArcB/ArcA. Represses a wide variety of aerobic enzymes under anaerobic conditions. It also may be involved in the osmoregulation of envelope proteins. When activated by ArcB, it negatively regulates the expression of genes of aerobic function. Activates the transcription of the plfB operon by binding to its promoter (By similarity). | Sensor protein torS; Escherichia coli K-12 ortholog: b0993; Escherichia coli O157:H7 ortholog: z1410. | 0.833 |
arcA | yedV | c5488 | c2386 | Aerobic respiration control protein arcA; Member of the two-component regulatory system ArcB/ArcA. Represses a wide variety of aerobic enzymes under anaerobic conditions. It also may be involved in the osmoregulation of envelope proteins. When activated by ArcB, it negatively regulates the expression of genes of aerobic function. Activates the transcription of the plfB operon by binding to its promoter (By similarity). | Putative sensor-like histidine kinase yedV; Member of a two-component regulatory system. | 0.580 |
arcB | arcA | c3970 | c5488 | Aerobic respiration control sensor protein arcB; Escherichia coli K-12 ortholog: b3210; Escherichia coli O157:H7 ortholog: z4574. | Aerobic respiration control protein arcA; Member of the two-component regulatory system ArcB/ArcA. Represses a wide variety of aerobic enzymes under anaerobic conditions. It also may be involved in the osmoregulation of envelope proteins. When activated by ArcB, it negatively regulates the expression of genes of aerobic function. Activates the transcription of the plfB operon by binding to its promoter (By similarity). | 0.995 |
arcB | envZ | c3970 | c4180 | Aerobic respiration control sensor protein arcB; Escherichia coli K-12 ortholog: b3210; Escherichia coli O157:H7 ortholog: z4574. | Osmolarity sensor protein envZ; Escherichia coli K-12 ortholog: b3404; Escherichia coli O157:H7 ortholog: z4759. | 0.832 |
arcB | ompR | c3970 | c4181 | Aerobic respiration control sensor protein arcB; Escherichia coli K-12 ortholog: b3210; Escherichia coli O157:H7 ortholog: z4574. | Transcriptional Regulatory protein ompR; Member of the two-component regulatory system EnvZ/OmpR involved in osmoregulation (particularly of genes ompF and ompC) as well as other genes. Plays a central role in both acid and osmotic stress responses. Binds to the promoter of both ompC and ompF; at low osmolarity it activates ompF transcription, while at high osmolarity it represses ompF and activates ompC transcription. | 0.934 |
arcB | rstA | c3970 | c2000 | Aerobic respiration control sensor protein arcB; Escherichia coli K-12 ortholog: b3210; Escherichia coli O157:H7 ortholog: z4574. | Transcriptional Regulatory protein rstA; Escherichia coli K-12 ortholog: b1608; Escherichia coli O157:H7 ortholog: z2609. | 0.890 |
arcB | rstB | c3970 | c2001 | Aerobic respiration control sensor protein arcB; Escherichia coli K-12 ortholog: b3210; Escherichia coli O157:H7 ortholog: z4574. | Sensor protein rstB; Escherichia coli K-12 ortholog: b1609; Escherichia coli O157:H7 ortholog: z2610. | 0.789 |
arcB | torR | c3970 | c1131 | Aerobic respiration control sensor protein arcB; Escherichia coli K-12 ortholog: b3210; Escherichia coli O157:H7 ortholog: z4574. | TorCAD operon transcriptional Regulatory protein torR; Escherichia coli K-12 ortholog: b0995; Escherichia coli O157:H7 ortholog: z1412. | 0.892 |
arcB | torS | c3970 | c1128 | Aerobic respiration control sensor protein arcB; Escherichia coli K-12 ortholog: b3210; Escherichia coli O157:H7 ortholog: z4574. | Sensor protein torS; Escherichia coli K-12 ortholog: b0993; Escherichia coli O157:H7 ortholog: z1410. | 0.993 |
arcB | torT | c3970 | c1130 | Aerobic respiration control sensor protein arcB; Escherichia coli K-12 ortholog: b3210; Escherichia coli O157:H7 ortholog: z4574. | Periplasmic protein torT precursor; Escherichia coli K-12 ortholog: b0994; Escherichia coli O157:H7 ortholog: z1411. | 0.748 |
arcB | yedV | c3970 | c2386 | Aerobic respiration control sensor protein arcB; Escherichia coli K-12 ortholog: b3210; Escherichia coli O157:H7 ortholog: z4574. | Putative sensor-like histidine kinase yedV; Member of a two-component regulatory system. | 0.686 |
arcB | yedW | c3970 | c2387 | Aerobic respiration control sensor protein arcB; Escherichia coli K-12 ortholog: b3210; Escherichia coli O157:H7 ortholog: z4574. | Probable transcriptional Regulatory protein yedW; Escherichia coli K-12 ortholog: b1969; Escherichia coli O157:H7 ortholog: z3061. | 0.885 |
envZ | arcA | c4180 | c5488 | Osmolarity sensor protein envZ; Escherichia coli K-12 ortholog: b3404; Escherichia coli O157:H7 ortholog: z4759. | Aerobic respiration control protein arcA; Member of the two-component regulatory system ArcB/ArcA. Represses a wide variety of aerobic enzymes under anaerobic conditions. It also may be involved in the osmoregulation of envelope proteins. When activated by ArcB, it negatively regulates the expression of genes of aerobic function. Activates the transcription of the plfB operon by binding to its promoter (By similarity). | 0.796 |
envZ | arcB | c4180 | c3970 | Osmolarity sensor protein envZ; Escherichia coli K-12 ortholog: b3404; Escherichia coli O157:H7 ortholog: z4759. | Aerobic respiration control sensor protein arcB; Escherichia coli K-12 ortholog: b3210; Escherichia coli O157:H7 ortholog: z4574. | 0.832 |
envZ | ompR | c4180 | c4181 | Osmolarity sensor protein envZ; Escherichia coli K-12 ortholog: b3404; Escherichia coli O157:H7 ortholog: z4759. | Transcriptional Regulatory protein ompR; Member of the two-component regulatory system EnvZ/OmpR involved in osmoregulation (particularly of genes ompF and ompC) as well as other genes. Plays a central role in both acid and osmotic stress responses. Binds to the promoter of both ompC and ompF; at low osmolarity it activates ompF transcription, while at high osmolarity it represses ompF and activates ompC transcription. | 0.999 |
envZ | rstA | c4180 | c2000 | Osmolarity sensor protein envZ; Escherichia coli K-12 ortholog: b3404; Escherichia coli O157:H7 ortholog: z4759. | Transcriptional Regulatory protein rstA; Escherichia coli K-12 ortholog: b1608; Escherichia coli O157:H7 ortholog: z2609. | 0.655 |
envZ | torR | c4180 | c1131 | Osmolarity sensor protein envZ; Escherichia coli K-12 ortholog: b3404; Escherichia coli O157:H7 ortholog: z4759. | TorCAD operon transcriptional Regulatory protein torR; Escherichia coli K-12 ortholog: b0995; Escherichia coli O157:H7 ortholog: z1412. | 0.714 |