STRINGSTRING
cusS cusS cusR cusR cusC cusC cusX cusX cusB cusB cusA cusA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cusSSensor kinase cusS; Member of the two-component regulatory system CusS/CusR involved in response to copper and silver. Acts as a copper/silver ion sensor. Activates CusR by phosphorylation. (480 aa)
cusRTranscriptional Regulatory protein cusR; Member of the two-component regulatory system CusS/CusR involved in response to copper and silver. (227 aa)
cusCProbable outer membrane lipoprotein cusC precursor; Forms pores that allow passive diffusion of cations across the outer membrane. Part of a cation efflux system that mediates resistance to copper and silver (By similarity); Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. (460 aa)
cusXHypothetical protein cusX precursor; Part of a cation efflux system that mediates resistance to copper and silver. Binds one copper per polypeptide (By similarity). (110 aa)
cusBPutative copper efflux system protein cusB precursor; Part of a cation efflux system that mediates resistance to copper and silver. (407 aa)
cusAPutative cation efflux system protein cusA; Part of a cation efflux system that mediates resistance to copper and silver; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1047 aa)
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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