STRINGSTRING
nagE nagE fryA fryA ptsH ptsH ptsI ptsI crr crr c4283 c4283 bglF bglF ptsA ptsA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
nagEPTS system, N-acetylglucosamine-specific IIABC component; EIIABC-NAG; Escherichia coli K-12 ortholog: b0679; Escherichia coli O157:H7 ortholog: z0826. (648 aa)
fryAPutative phosphoenolpyruvate-protein phosphotransferase ypdD; Multifunctional protein that includes general (non sugar- specific) and sugar-specific components of the phosphoenolpyruvate- dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FryABC PTS system is involved in fructose transport. (831 aa)
ptsHPhosphocarrier protein HPr; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain. (85 aa)
ptsIPhosphoenolpyruvate-protein phosphotransferase; Escherichia coli K-12 ortholog: b2416; Escherichia coli O157:H7 ortholog: z3682. (498 aa)
crrPTS system, glucose-specific IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II complex composed of PtsG and Crr is involved in glucose transport. (169 aa)
c4283Putative phosphocarrier protein; Escherichia coli O157:H7 ortholog: z4879. (89 aa)
bglFPTS system, beta-glucoside-specific IIABC component; EIIABC-Bgl; Escherichia coli K-12 ortholog: b3722. (649 aa)
ptsAPhosphoenolpyruvate-protein phosphotransferase ptsA; Escherichia coli K-12 ortholog: b3947; Escherichia coli O157:H7 ortholog: z5502. (833 aa)
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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