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ydfH ydfH c1968 c1968 ydfJ ydfJ rspB rspB rspA rspA ynfA ynfA ynfB ynfB speG speG c2236 c2236 yebQ yebQ kduD kduD kduI kduI uxaA uxaA uxaC uxaC exuT exuT exuR exuR kdgK kdgK yieO yieO yieP yieP kdgT kdgT c4920 c4920 uxuA uxuA uxuB uxuB uxuR uxuR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ydfHHypothetical transcriptional regulator ydfH; Escherichia coli K-12 ortholog: b1540; Escherichia coli O157:H7 ortholog: z2157. (228 aa)
c1968Hypothetical oxidoreductase ydfI; Escherichia coli K-12 ortholog: b1542; Escherichia coli O157:H7 ortholog: z2155; Belongs to the mannitol dehydrogenase family. (486 aa)
ydfJHypothetical metabolite transport protein ydfJ; Escherichia coli K-12 ortholog: b1543; Escherichia coli O157:H7 ortholog: z2153. (455 aa)
rspBStarvation sensing protein rspB; Escherichia coli K-12 ortholog: b1580. (347 aa)
rspAStarvation sensing protein rspA; Has low D-mannonate dehydratase activity (in vitro), suggesting that this is not a physiological substrate and that it has no significant role in D-mannonate degradation in vivo. Has no detectable activity with a panel of 70 other acid sugars (in vitro). Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily. (415 aa)
ynfAHypothetical protein ynfA; Escherichia coli K-12 ortholog: b1582; Escherichia coli O157:H7 ortholog: z2569. (111 aa)
ynfBHypothetical protein ynfB precursor; Escherichia coli K-12 ortholog: b1583; Escherichia coli O157:H7 ortholog: z2570; Belongs to the UPF0482 family. (113 aa)
speGSpermidine N(1)-acetyltransferase; Escherichia coli K-12 ortholog: b1584; Escherichia coli O157:H7 ortholog: z2571. (186 aa)
c2236Transcriptional regulator kdgR; Escherichia coli K-12 ortholog: b1827; Escherichia coli O157:H7 ortholog: z2874. (263 aa)
yebQHypothetical transport protein yebQ; Escherichia coli K-12 ortholog: b1828; Escherichia coli O157:H7 ortholog: z2875. (494 aa)
kduD2-deoxy-D-gluconate 3-dehydrogenase; Escherichia coli K-12 ortholog: b2842; Escherichia coli O157:H7 ortholog: z4162. (253 aa)
kduI4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. (278 aa)
uxaAAltronate hydrolase; Escherichia coli K-12 ortholog: b3091; Escherichia coli O157:H7 ortholog: z4444. (495 aa)
uxaCUronate isomerase; Escherichia coli K-12 ortholog: b3092; Escherichia coli O157:H7 ortholog: z4445. (491 aa)
exuTHexuronate transporter; Escherichia coli K-12 ortholog: b3093; Escherichia coli O157:H7 ortholog: z4446. (472 aa)
exuRExu regulon transcriptional regulator; Escherichia coli K-12 ortholog: b3094; Escherichia coli O157:H7 ortholog: z4448. (263 aa)
kdgK2-dehydro-3-deoxygluconokinase; Escherichia coli K-12 ortholog: b3526; Escherichia coli O157:H7 ortholog: z4940. (425 aa)
yieOHypothetical transport protein yieO; Escherichia coli K-12 ortholog: b3754; Escherichia coli O157:H7 ortholog: z5255; Belongs to the major facilitator superfamily. (475 aa)
yiePHypothetical transcriptional regulator yieP; Escherichia coli K-12 ortholog: b3755; Escherichia coli O157:H7 ortholog: z5258. (230 aa)
kdgT2-keto-3-deoxygluconate permease; The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity); Belongs to the KdgT transporter family. (341 aa)
c4920Starvation sensing protein rspA; Escherichia coli K-12 ortholog: b1581. (404 aa)
uxuAMannonate dehydratase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family. (394 aa)
uxuBD-mannonate oxidoreductase; Escherichia coli K-12 ortholog: b4323; Escherichia coli O157:H7 ortholog: z5921; Belongs to the mannitol dehydrogenase family. (486 aa)
uxuRUxu operon transcriptional regulator; Escherichia coli K-12 ortholog: b4324; Escherichia coli O157:H7 ortholog: z5922. (257 aa)
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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