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fliH fliH flgM flgM flgN flgN fliP fliP fliO fliO fliK fliK fliJ fliJ fliR fliR fliI fliI fliQ fliQ flgD flgD flgJ flgJ flgK flgK flhA flhA flhB flhB flhC flhC flhD flhD fliS fliS fliT fliT flgA flgA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fliHFlagellar assembly protein fliH; Escherichia coli K-12 ortholog: b1940; Escherichia coli O157:H7 ortholog: z3030. (235 aa)
flgMNegative regulator of flagellin synthesis; Anti-sigma-28 factor; Escherichia coli K-12 ortholog: b1071; Escherichia coli O157:H7 ortholog: z1709. (97 aa)
flgNFlagella synthesis protein flgN; Escherichia coli K-12 ortholog: b1070; Escherichia coli O157:H7 ortholog: z1708. (138 aa)
fliPFlagellar biosynthetic protein fliP precursor; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. (245 aa)
fliOFlagellar protein fliO; Escherichia coli K-12 ortholog: b1947; Escherichia coli O157:H7 ortholog: z3037. (122 aa)
fliKFlagellar hook-length control protein; Escherichia coli K-12 ortholog: b1943; Escherichia coli O157:H7 ortholog: z3033. (375 aa)
fliJFlagellar fliJ protein; Flagellar protein that affects chemotactic events. Belongs to the FliJ family. (147 aa)
fliRFlagellar biosynthetic protein fliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family. (261 aa)
fliIFlagellum-specific ATP synthase; Escherichia coli K-12 ortholog: b1941; Escherichia coli O157:H7 ortholog: z3031. (457 aa)
fliQFlagellar biosynthetic protein fliQ; Required for the assembly of the rivet at the earliest stage of flagellar biosynthesis; Belongs to the FliQ/MopD/SpaQ family. (89 aa)
flgDBasal-body rod modification protein flgD; Required for flagellar hook formation. May act as a scaffolding protein. (231 aa)
flgJPeptidoglycan hydrolase flgJ; Escherichia coli K-12 ortholog: b1081; Escherichia coli O157:H7 ortholog: z1719. (323 aa)
flgKFlagellar hook-associated protein 1; HAP1; Escherichia coli K-12 ortholog: b1082; Escherichia coli O157:H7 ortholog: z1720. (547 aa)
flhAFlagellar biosynthesis protein flhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. (717 aa)
flhBFlagellar biosynthetic protein flhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family. (382 aa)
flhCFlagellar transcriptional activator flhC; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family. (192 aa)
flhDFlagellar transcriptional activator flhD; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family. (119 aa)
fliSFlagellar protein fliS; Escherichia coli K-12 ortholog: b1925; Escherichia coli O157:H7 ortholog: z3015. (136 aa)
fliTFlagellar protein fliT; Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus. (121 aa)
flgAFlagella basal body P-ring formation protein flgA precursor; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family. (219 aa)
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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