15 items (Escherichia coli CFT073) - STRING interaction network

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	sppA	Protease IV; Escherichia coli K-12 ortholog: b1766; Escherichia coli O157:H7 ortholog: z2799. (618 aa)
	hyaD	Hydrogenase 1 maturation protease; Escherichia coli K-12 ortholog: b0975; Escherichia coli O157:H7 ortholog: z1392. (195 aa)
	lipB	Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (213 aa)
	lipA	Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (321 aa)
	c0326	Hypothetical protein; Residues 1 to 142 of 142 are 86.71 pct identical to residues 83 to 225 of 228 from GenPept.129 : >emb\|CAC43418.1\| (X16664) hypothetical protein [Escherichia coli]. (142 aa)
	lepB	Signal peptidase I; Escherichia coli K-12 ortholog: b2568; Escherichia coli O157:H7 ortholog: z3850; Belongs to the peptidase S26 family. (324 aa)
	yhgI	Protein yhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. (191 aa)
	lplA	Lipoate-protein ligase A; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. (338 aa)
	rimI	Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. (148 aa)
	yhhK	Hypothetical protein yhhK; Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion; Belongs to the PanZ/PanM family. (127 aa)
	hybD	Hydrogenase 2 maturation protease; Escherichia coli K-12 ortholog: b2993; Escherichia coli O157:H7 ortholog: z4347. (164 aa)
	hybF	Probable hydrogenase nickel incorporation protein hybF; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (113 aa)
	hypB	Hydrogenase isoenzymes nickel incorporation protein hypB; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Exhibits a low intrinsic GTPase activity, which is essential for nickel insertion. (290 aa)
	hypA	HypA protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (120 aa)
	c1233	Hypothetical protein; Residues 1 to 228 of 228 are 96.92 pct identical to residues 1 to 228 of 228 from GenPept.129 : >emb\|CAC43418.1\| (X16664) hypothetical protein [Escherichia coli]. (228 aa)

Your Current Organism:

Escherichia coli CFT073

NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
c0326	yhhK	c0326	c4251	Hypothetical protein; Residues 1 to 142 of 142 are 86.71 pct identical to residues 83 to 225 of 228 from GenPept.129 : >emb\|CAC43418.1\| (X16664) hypothetical protein [Escherichia coli].	Hypothetical protein yhhK; Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion; Belongs to the PanZ/PanM family.	0.472
hyaD	hybF	c1116	c3728	Hydrogenase 1 maturation protease; Escherichia coli K-12 ortholog: b0975; Escherichia coli O157:H7 ortholog: z1392.	Probable hydrogenase nickel incorporation protein hybF; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.	0.725
hyaD	hypA	c1116	c3286	Hydrogenase 1 maturation protease; Escherichia coli K-12 ortholog: b0975; Escherichia coli O157:H7 ortholog: z1392.	HypA protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.	0.674
hyaD	hypB	c1116	c3287	Hydrogenase 1 maturation protease; Escherichia coli K-12 ortholog: b0975; Escherichia coli O157:H7 ortholog: z1392.	Hydrogenase isoenzymes nickel incorporation protein hypB; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Exhibits a low intrinsic GTPase activity, which is essential for nickel insertion.	0.686
hybD	hybF	c3730	c3728	Hydrogenase 2 maturation protease; Escherichia coli K-12 ortholog: b2993; Escherichia coli O157:H7 ortholog: z4347.	Probable hydrogenase nickel incorporation protein hybF; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.	0.947
hybD	hypA	c3730	c3286	Hydrogenase 2 maturation protease; Escherichia coli K-12 ortholog: b2993; Escherichia coli O157:H7 ortholog: z4347.	HypA protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.	0.694
hybD	hypB	c3730	c3287	Hydrogenase 2 maturation protease; Escherichia coli K-12 ortholog: b2993; Escherichia coli O157:H7 ortholog: z4347.	Hydrogenase isoenzymes nickel incorporation protein hypB; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Exhibits a low intrinsic GTPase activity, which is essential for nickel insertion.	0.753
hybF	hyaD	c3728	c1116	Probable hydrogenase nickel incorporation protein hybF; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.	Hydrogenase 1 maturation protease; Escherichia coli K-12 ortholog: b0975; Escherichia coli O157:H7 ortholog: z1392.	0.725
hybF	hybD	c3728	c3730	Probable hydrogenase nickel incorporation protein hybF; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.	Hydrogenase 2 maturation protease; Escherichia coli K-12 ortholog: b2993; Escherichia coli O157:H7 ortholog: z4347.	0.947
hybF	hypB	c3728	c3287	Probable hydrogenase nickel incorporation protein hybF; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.	Hydrogenase isoenzymes nickel incorporation protein hypB; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Exhibits a low intrinsic GTPase activity, which is essential for nickel insertion.	0.962
hypA	hyaD	c3286	c1116	HypA protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.	Hydrogenase 1 maturation protease; Escherichia coli K-12 ortholog: b0975; Escherichia coli O157:H7 ortholog: z1392.	0.674
hypA	hybD	c3286	c3730	HypA protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.	Hydrogenase 2 maturation protease; Escherichia coli K-12 ortholog: b2993; Escherichia coli O157:H7 ortholog: z4347.	0.694
hypA	hypB	c3286	c3287	HypA protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.	Hydrogenase isoenzymes nickel incorporation protein hypB; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Exhibits a low intrinsic GTPase activity, which is essential for nickel insertion.	0.999
hypB	hyaD	c3287	c1116	Hydrogenase isoenzymes nickel incorporation protein hypB; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Exhibits a low intrinsic GTPase activity, which is essential for nickel insertion.	Hydrogenase 1 maturation protease; Escherichia coli K-12 ortholog: b0975; Escherichia coli O157:H7 ortholog: z1392.	0.686
hypB	hybD	c3287	c3730	Hydrogenase isoenzymes nickel incorporation protein hypB; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Exhibits a low intrinsic GTPase activity, which is essential for nickel insertion.	Hydrogenase 2 maturation protease; Escherichia coli K-12 ortholog: b2993; Escherichia coli O157:H7 ortholog: z4347.	0.753
hypB	hybF	c3287	c3728	Hydrogenase isoenzymes nickel incorporation protein hypB; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Exhibits a low intrinsic GTPase activity, which is essential for nickel insertion.	Probable hydrogenase nickel incorporation protein hybF; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.	0.962
hypB	hypA	c3287	c3286	Hydrogenase isoenzymes nickel incorporation protein hypB; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. Exhibits a low intrinsic GTPase activity, which is essential for nickel insertion.	HypA protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.	0.999
lipA	lipB	c0718	c0720	Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.	0.999
lipA	lplA	c0718	c5471	Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	Lipoate-protein ligase A; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.	0.990
lipA	yhgI	c0718	c4191	Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	Protein yhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.	0.542