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| | iroC | ATP binding cassette (ABC) transporter homolog; Residues 27 to 1231 of 1245 are 80.16 pct identical to residues 1 to 1209 of 1218 from GenPept.129 : >emb|CAD05883.1| (AL627276) putative ABC transporter protein [Salmonella enterica subsp. enterica serovar Typhi]. (1245 aa) |
| | ytjA | Conserved hypothetical protein; Escherichia coli O157:H7 ortholog: z5978. (63 aa) |
| | yjiY | Hypothetical protein yjiY; Escherichia coli K-12 ortholog: b4354; Escherichia coli O157:H7 ortholog: z5953. (721 aa) |
| | nanC | Hypothetical protein yjhA precursor; Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria. NanC proteins form high-conductance channels which are open at low membrane potentials and which have a weak anion selectivity (By similarity). (241 aa) |
| | yjgQ | Hypothetical protein yjgQ; Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. (361 aa) |
| | yjgP | Hypothetical protein yjgP; Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. (366 aa) |
| | ytfR | Putative ATP-binding component of a transport system; Escherichia coli K-12 ortholog: b4228; Escherichia coli O157:H7 ortholog: z5839. (500 aa) |
| | ytfN | Hypothetical protein ytfN; Escherichia coli K-12 ortholog: b4221; Escherichia coli O157:H7 ortholog: z5832. (1259 aa) |
| | ytfM | Hypothetical protein ytfM precursor; Escherichia coli K-12 ortholog: b4220; Escherichia coli O157:H7 ortholog: z5831. (577 aa) |
| | yjeT | Hypothetical protein yjeT; Escherichia coli K-12 ortholog: b4176; Escherichia coli O157:H7 ortholog: z5783. (65 aa) |
| | hflC | HflC protein; HflC and HflK help govern the stability of phage lambda cII protein, and thereby control the lysogenization frequency of phage lambda. HflKC inhibits the SecY-degrading activity of FtsH, possibly helping quality control of integral membrane proteins (By similarity). (334 aa) |
| | hflK | HflK protein; HflC and HflK could encode or regulate a protease. (419 aa) |
| | frdD | Fumarate reductase 13 kDa hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (129 aa) |
| | c5223 | FxsA protein; Suppressor of F exclusion of phage T7; Escherichia coli K-12 ortholog: b4140; Escherichia coli O157:H7 ortholog: z5745. (158 aa) |
| | yjdH | Sensor protein dcuS; Member of the two-component regulatory system DcuR/DcuS. Involved in the C4-dicarboxylate-stimulated regulation of the genes encoding the anaerobic fumarate respiratory system (frdABCD; nuoAN; dcuB; dcuC; sdhCDAB; etc.). Weakly regulates the aerobic C4- dicarboxylate transporter dctA. Activates DcuR by phosphorylation (By similarity). (543 aa) |
| | phnE | Membrane channel protein component of Pn transporter; Escherichia coli O157:H7 ortholog: z5706. (280 aa) |
| | yjcG | Putative symporter yjcG; Transports acetate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (549 aa) |
| | lamB | Maltoporin precursor; Involved in the transport of maltose and maltodextrins. Belongs to the porin LamB (TC 1.B.3) family. (446 aa) |
| | malK | Maltose/maltodextrin transport ATP-binding protein malK; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family. (401 aa) |
| | malE | Maltose-binding periplasmic protein precursor; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family. (396 aa) |
| | malF | Maltose transport system permease protein malF; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. (519 aa) |
| | malG | Maltose transport system permease protein malG; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. (296 aa) |
| | c4985 | Putative sorbose PTS component; Escherichia coli O157:H7 ortholog: z5617. (135 aa) |
| | c4984 | Putative sorbose PTS component; Escherichia coli O157:H7 ortholog: z5616. (164 aa) |
| | c4983 | PTS system, mannose-specific IIC component; EIIC-Man; Escherichia coli K-12 ortholog: b1818; Escherichia coli O157:H7 ortholog: z5615. (265 aa) |
| | c4982 | PTS system, mannose-specific IID component; EIID-Man; Escherichia coli K-12 ortholog: b1819; Escherichia coli O157:H7 ortholog: z5614. (284 aa) |
| | secE | Preprotein translocase secE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (127 aa) |
| | btuB | Vitamin B12 receptor precursor; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily. (629 aa) |
| | argH | Argininosuccinate lyase; Escherichia coli K-12 ortholog: b3960; Escherichia coli O157:H7 ortholog: z5518. (457 aa) |
| | c4894 | Nucleoside-specific channel-forming protein tsx precursor; Escherichia coli K-12 ortholog: b0411; Escherichia coli O157:H7 ortholog: z0512. (286 aa) |
| | ftsN | Cell division protein ftsN; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. (319 aa) |
| | sbp | Sulfate-binding protein precursor; Sulfate starvation-induced protein 2; Escherichia coli K-12 ortholog: b3917; Escherichia coli O157:H7 ortholog: z5462. (329 aa) |
| | cpxA | Sensor protein cpxA; This protein is involved in several diverse cellular processes, such as the functioning of acetohydroxyacid synthetase I, in the biosynthesis of isoleucine and valine, the TraJ protein activation activity for tra gene expression in F plasmid, and the synthesis, translocation, or stability of cell envelope proteins. Activates CpxR by phosphorylation (By similarity). (457 aa) |
| | kdgT | 2-keto-3-deoxygluconate permease; The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity); Belongs to the KdgT transporter family. (341 aa) |
| | trkH | Trk system potassium uptake protein trkH; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family. (483 aa) |
| | yigU | Sec-independent protein translocase protein tatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (258 aa) |
| | tatB | Sec-independent protein translocase protein tatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (171 aa) |
| | tatA | Sec-independent protein translocase protein tatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (103 aa) |
| | pldA | Phospholipase A1 precursor; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family. (289 aa) |
| | rarD | Protein rarD; Escherichia coli K-12 ortholog: b3819; Escherichia coli O157:H7 ortholog: z5340. (296 aa) |
| | rbsC | Ribose transport system permease protein rbsC; Part of the ABC transporter complex RbsABC involved in ribose import. Probably responsible for the translocation of the substrate across the membrane. (321 aa) |
| | rbsA | Ribose transport ATP-binding protein rbsA; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (501 aa) |
| | pstC | Phosphate transport system permease protein pstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (319 aa) |
| | yidC | 60 kDa inner-membrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. (548 aa) |
| | dgoT | D-galactonate transporter; Intake of galactonate into the cell; Belongs to the major facilitator superfamily. Phthalate permease family. (445 aa) |
| | yidS | Hypothetical protein yidS precursor; Escherichia coli K-12 ortholog: b3690; Escherichia coli O157:H7 ortholog: z5186; Belongs to the CbrA family. (373 aa) |
| | emrD | Multidrug resistance protein D; Escherichia coli K-12 ortholog: b3673; Escherichia coli O157:H7 ortholog: z5168. (396 aa) |
| | uhpC | Regulatory protein uhpC; Escherichia coli K-12 ortholog: b3667; Escherichia coli O157:H7 ortholog: z5157. (440 aa) |
| | yicO | Hypothetical protein yicO; Escherichia coli K-12 ortholog: b3664; Escherichia coli O157:H7 ortholog: z5209. (470 aa) |
| | c4551 | Hypothetical protein; Residues 33 to 328 of 354 are 21.82 pct identical to residues 185 to 490 of 1046 from GenPept.129 : >gb|AAG03815.1|AE004479_10 (AE004479) RND multidrug efflux transporter MexB [Pseudomonas aeruginosa]; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (354 aa) |
| | yicE | Putative purine permease yicE; Specific, proton motive force-dependent high-affinity transporter for xanthine; Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily. (466 aa) |
| | mtlA | PTS system, mannitol-specific IIABC component; EIIABC-MTL; Escherichia coli K-12 ortholog: b3599; Escherichia coli O157:H7 ortholog: z5023. (637 aa) |
| | xylG | D-xylose transport ATP-binding protein xylG; Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Xylose importer (TC 3.A.1.2.4) family. (525 aa) |
| | emrA | Multidrug resistance protein A; Escherichia coli K-12 ortholog: b2685; Escherichia coli O157:H7 ortholog: z3986. (394 aa) |
| | ygcN | Probable electron transfer flavoprotein-quinone oxidoreductase ygcN; Part of an electron transfer system. Belongs to the ETF-QO/FixC family. (433 aa) |
| | ygcO | Ferredoxin-like protein ygcO; Could be a 3Fe-4S cluster-containing protein. (98 aa) |
| | fucP | L-fucose permease; Escherichia coli K-12 ortholog: b2801; Escherichia coli O157:H7 ortholog: z4118. (438 aa) |
| | lgt | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (291 aa) |
| | araE | Arabinose-proton symporter; Arabinose transporter; Escherichia coli K-12 ortholog: b2841; Escherichia coli O157:H7 ortholog: z4161; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (515 aa) |
| | ygfO | Putative purine permease ygfO; Specific, proton motive force-dependent high-affinity transporter for xanthine; Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily. (485 aa) |
| | ygfU | Putative purine permease ygfU; Escherichia coli K-12 ortholog: b2888; Escherichia coli O157:H7 ortholog: z4226. (525 aa) |
| | ygfX | Hypothetical protein ygfX; Escherichia coli K-12 ortholog: b2896; Escherichia coli O157:H7 ortholog: z4234. (135 aa) |
| | yggE | Hypothetical protein yggE; Escherichia coli K-12 ortholog: b2922; Escherichia coli O157:H7 ortholog: z4259. (246 aa) |
| | yggB | Hypothetical protein yggB; Escherichia coli K-12 ortholog: b2924; Escherichia coli O157:H7 ortholog: z4261. (286 aa) |
| | c3509 | Putative ATP-binding protein of ABC transport system; Escherichia coli O157:H7 ortholog: z4270. (178 aa) |
| | c3510 | Putative ATP-binding protein of ABC transport system; Escherichia coli O157:H7 ortholog: z4271. (236 aa) |
| | c3517 | Hypothetical protein; Residues 38 to 224 of 244 are 48.93 pct identical to residues 18 to 205 of 308 from GenPept.129 : >emb|CAC90171.1| (AJ414147) putative SPFH domain protein [Yersinia pestis]. (244 aa) |
| | shiF | shiF protein; Residues 1 to 397 of 397 are 99.74 pct identical to residues 1 to 397 of 397 from GenPept.129 : >gb|AAD44744.1|AF141323_15 (AF141323) ShiF [Shigella flexneri]. (397 aa) |
| | c3635 | Hypothetical protein yjhA precursor; Escherichia coli K-12 ortholog: b4311; Escherichia coli O157:H7 ortholog: z5907. (246 aa) |
| | kpsD | KpsD protein; Residues 2 to 559 of 559 are 99.46 pct identical to residues 1 to 558 of 558 from SwissProt.40 : >sp|P42213|KSD5_ECOLI POLYSIALIC ACID TRANSPORT PROTEIN KPSD PRECURSOR. (559 aa) |
| | fhuC | Ferrichrome transport ATP-binding protein fhuC; Escherichia coli K-12 ortholog: b0151; Escherichia coli O157:H7 ortholog: z0162. (300 aa) |
| | c3716 | Hypothetical protein; Residues 30 to 379 of 386 are 29.17 pct identical to residues 4 to 354 of 358 from GenPept.129 : >emb|CAC92669.1| (AJ414157) putative membrane protein [Yersinia pestis]. (386 aa) |
| | c3717 | Hypothetical protein; Residues 3 to 342 of 356 are 29.54 pct identical to residues 2 to 350 of 372 from GenPept.129 : >gb|AAG07215.1|AE004800_4 (AE004800) conserved hypothetical protein [Pseudomonas aeruginosa]. (356 aa) |
| | pitB | Probable low-affinity inorganic phosphate transporter 2; Escherichia coli K-12 ortholog: b2987; Escherichia coli O157:H7 ortholog: z4893. (499 aa) |
| | exbD | Biopolymer transport exbD protein; Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. (141 aa) |
| | exbB | Biopolymer transport exbB protein; Escherichia coli K-12 ortholog: b3006; Escherichia coli O157:H7 ortholog: z4359. (244 aa) |
| | yghB | Hypothetical protein yghB; Escherichia coli K-12 ortholog: b3009; Escherichia coli O157:H7 ortholog: z4362. (219 aa) |
| | tolC | Outer membrane protein tolC precursor; Escherichia coli K-12 ortholog: b3035; Escherichia coli O157:H7 ortholog: z4392. (506 aa) |
| | ygiM | Hypothetical protein ygiM precursor; Escherichia coli K-12 ortholog: b3055; Escherichia coli O157:H7 ortholog: z4408. (206 aa) |
| | bacA | Putative undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (274 aa) |
| | agaV | PTS system, N-acetylgalactosamine-specific IIB component 2; EIIB-AGA'; Escherichia coli K-12 ortholog: b3133; Escherichia coli O157:H7 ortholog: z4485. (169 aa) |
| | c3891 | Putative phosphotransferase system enzyme subunit; Escherichia coli O157:H7 ortholog: z4488. (144 aa) |
| | agaB | PTS system, N-acetylgalactosamine-specific IIB component 1; EIIB-AGA; Escherichia coli K-12 ortholog: b3138; Escherichia coli O157:H7 ortholog: z4492. (158 aa) |
| | yrbD | Hypothetical protein yrbD precursor; Escherichia coli K-12 ortholog: b3193; Escherichia coli O157:H7 ortholog: z4556. (188 aa) |
| | yrbE | Hypothetical protein yrbE; Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane. (260 aa) |
| | yrbK | Hypothetical protein yrbK; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. (191 aa) |
| | yhbG | Probable ABC transporter ATP-binding protein yhbG; Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system (By similarity). (241 aa) |
| | yhdP | Hypothetical protein yhdP; Escherichia coli K-12 ortholog: b3245; Escherichia coli O157:H7 ortholog: z4604. (1266 aa) |
| | acrE | Acriflavine resistance protein E precursor; Protein envC; Escherichia coli K-12 ortholog: b3265; Escherichia coli O157:H7 ortholog: z4625; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (385 aa) |
| | mscL | Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. (137 aa) |
| | kefB | Glutathione-regulated potassium-efflux system protein kefB; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. (601 aa) |
| | yheR | Putative NAD(P)H oxidoreductase yheR; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB. (184 aa) |
| | yhfC | Hypothetical protein yhfC; Escherichia coli K-12 ortholog: b3364; Escherichia coli O157:H7 ortholog: z4725. (393 aa) |
| | envZ | Osmolarity sensor protein envZ; Escherichia coli K-12 ortholog: b3404; Escherichia coli O157:H7 ortholog: z4759. (450 aa) |
| | glpG | Protein glpG; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. (276 aa) |
| | glpD | Aerobic glycerol-3-phosphate dehydrogenase; Escherichia coli K-12 ortholog: b3426; Escherichia coli O157:H7 ortholog: z4786; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (506 aa) |
| | ugpC | SN-glycerol-3-phosphate transport ATP-binding protein ugpC; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. sn-glycerol-3- phosphate importer (TC 3.A.1.1.3) family. (369 aa) |
| | ugpE | SN-glycerol-3-phosphate transport system permease protein ugpE; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane. (281 aa) |
| | ugpA | SN-glycerol-3-phosphate transport system permease protein ugpA; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane. (295 aa) |
| | ugpB | Glycerol-3-phosphate-binding periplasmic protein precursor; sn-glycerol-3-phosphate and glycerophosphoryl diester-binding protein interacts with the binding protein-dependent transport system UgpACE. (438 aa) |
| | yhiP | Hypothetical transporter yhiP; Proton-dependent permease that transports di- and tripeptides; Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpB subfamily. (489 aa) |
| | dctA | Aerobic C4-dicarboxylate transport protein; Responsible for the aerobic transport of the dicarboxylates fumarate and malate and to a lesser extent succinate, from the periplasm across the inner membrane; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (428 aa) |
| | fhuB | Ferrichrome uptake protein fhuB; Escherichia coli K-12 ortholog: b0153; Escherichia coli O157:H7 ortholog: z0164; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (660 aa) |
| | yadT | Vitamin B12 transport protein btuF precursor; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. (266 aa) |
| | yaeC | D-methionine-binding lipoprotein metQ precursor; Escherichia coli K-12 ortholog: b0197; Escherichia coli O157:H7 ortholog: z0209; Belongs to the nlpA lipoprotein family. (270 aa) |
| | yaeE | D-methionine transport system permease protein metI; Escherichia coli K-12 ortholog: b0198; Escherichia coli O157:H7 ortholog: z0210. (217 aa) |
| | abc | D-methionine transport ATP-binding protein metN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (343 aa) |
| | c0295 | Hypothetical protein; Residues 1 to 330 of 330 are 99.39 pct identical to residues 1 to 332 of 332 from GenPept.129 : >gb|AAL67368.1|AF447814_36 (AF447814) iron-chelating periplasmic-binding protein [Escherichia coli]. (330 aa) |
| | c0332 | Putative L-fucose permease; Residues 1 to 438 of 438 are 96.11 pct identical to residues 1 to 438 of 438 from GenPept.129 : >gb|AAL22650.1| (AE008876) putative L-fucose permease [Salmonella typhimurium LT2]. (438 aa) |
| | mbhA | MbhA protein; Escherichia coli K-12 ortholog: b0230; Escherichia coli O157:H7 ortholog: z0291. (262 aa) |
| | phoE | Outer membrane pore protein E precursor; Escherichia coli K-12 ortholog: b0241; Escherichia coli O157:H7 ortholog: z0302; Belongs to the Gram-negative porin family. (353 aa) |
| | lacY | Lactose-proton symport; Escherichia coli K-12 ortholog: b0343; Escherichia coli O157:H7 ortholog: z0439. (417 aa) |
| | sbmA | SbmA protein; Escherichia coli K-12 ortholog: b0377; Escherichia coli O157:H7 ortholog: z0473. (408 aa) |
| | phoR | Phosphate regulon sensor protein phoR; Escherichia coli K-12 ortholog: b0400; Escherichia coli O157:H7 ortholog: z0498. (431 aa) |
| | yajC | Hypothetical protein yajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. (120 aa) |
| | tsx | Nucleoside-specific channel-forming protein tsx precursor; Escherichia coli K-12 ortholog: b0411; Escherichia coli O157:H7 ortholog: z0512. (310 aa) |
| | pgpA | Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). (172 aa) |
| | yajR | Hypothetical transport protein yajR; Escherichia coli K-12 ortholog: b0427; Escherichia coli O157:H7 ortholog: z0530. (520 aa) |
| | cyoD | Ubiquinol oxidase chain D; Escherichia coli K-12 ortholog: b0429; Escherichia coli O157:H7 ortholog: z0532. (109 aa) |
| | cyoC | Cytochrome O ubiquinol oxidase subunit III; Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron (By similarity). (204 aa) |
| | ybaU | Peptidyl-prolyl cis-trans isomerase D; PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins (By similarity). (623 aa) |
| | amtB | Probable ammonium transporter; Escherichia coli K-12 ortholog: b0451; Escherichia coli O157:H7 ortholog: z0563. (428 aa) |
| | acrB | Acriflavine resistance protein B; Escherichia coli K-12 ortholog: b0462; Escherichia coli O157:H7 ortholog: z0576. (1049 aa) |
| | cusA | Putative cation efflux system protein cusA; Part of a cation efflux system that mediates resistance to copper and silver; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1047 aa) |
| | fepA | Ferrienterobactin receptor precursor; Enterobactin outer-membrane receptor; Escherichia coli K-12 ortholog: b0584; Escherichia coli O157:H7 ortholog: z0724. (746 aa) |
| | crcB | Protein crcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (127 aa) |
| | dacA | Penicillin-binding protein 5 precursor; Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Belongs to the peptidase S11 family. (403 aa) |
| | c0741 | Hypothetical protein; Residues 15 to 253 of 625 are 35.54 pct identical to residues 22 to 275 of 281 from GenPept.129 : >gb|AAA61597.1| (L28755) 2'-N-acetyltransferase [Providencia stuartii]. (625 aa) |
| | lnt | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation. Utilizes a two-step reaction via a ping-pong mechanism. Lnt undergoes covalent modification in the presence of phospholipids, resulting in a thioester acyl-enzyme intermediate. It then transfers the acyl chain to the amine group of the N-terminal diacylglyceryl- modified cysteine of apolipoprotein, leading to the formation of mature triacylated lipoprotein; Belongs to the CN hydrolase family. Apolipoprotein N- acyltra [...] (512 aa) |
| | kdpC | Potassium-transporting ATPase C chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (198 aa) |
| | kdpB | Potassium-transporting ATPase B chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (682 aa) |
| | kdpA | Potassium-transporting ATPase A chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (557 aa) |
| | ybgH | Hypothetical transporter ybgH; Probable proton-dependent permease that transports dipeptides; Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpD subfamily. (493 aa) |
| | cydA | Cytochrome D ubiquinol oxidase subunit I; A terminal oxidase that produces a proton motive force by the vectorial transfer of protons across the inner membrane. It is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at low aeration. Generates a proton motive force using protons and electrons from opposite sides of the membrane to generate H(2)O, transferring 1 proton/electron. Belongs to the cytochrome ubiquinol oxidase subunit 1 family. (523 aa) |
| | tolQ | TolQ protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. (230 aa) |
| | tolR | TolR protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. (142 aa) |
| | modF | Putative molybdenum transport ATP-binding protein modF; Photorepair protein phrA; Escherichia coli K-12 ortholog: b0760; Escherichia coli O157:H7 ortholog: z0930. (494 aa) |
| | ybhR | Hypothetical protein ybhR; Escherichia coli K-12 ortholog: b0792; Escherichia coli O157:H7 ortholog: z1012. (368 aa) |
| | ybhS | Hypothetical protein ybhS; Part of the ABC transporter complex YbhFSR that could be involved in efflux of cefoperazone. Probably involved in the translocation of the substrate across the membrane. (377 aa) |
| | ybiL | Probable tonB-dependent receptor ybiL precursor; Involved in the active transport across the outer membrane of iron complexed with catecholate siderophores such as dihydroxybenzoylserine and dihydroxybenzoate. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB. Can also transport catechol-substituted cephalosporins. Receptor for microcins M, H47 and E492 (By similarity). (760 aa) |
| | cmr | Multidrug translocase mdfA; Efflux pump driven by the proton motive force. Confers resistance to a broad spectrum of chemically unrelated drugs (By similarity). (420 aa) |
| | potG | Putrescine transport ATP-binding protein potG; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (404 aa) |
| | potH | Putrescine transport system permease protein potH; Escherichia coli K-12 ortholog: b0856; Escherichia coli O157:H7 ortholog: z1083. (314 aa) |
| | potI | Putrescine transport system permease protein potI; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (295 aa) |
| | aqpZ | Aquaporin Z; Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity); Belongs to the MIP/aquaporin (TC 1.A.8) family. (233 aa) |
| | macA | Macrolide-specific efflux protein macA precursor; Escherichia coli K-12 ortholog: b0878; Escherichia coli O157:H7 ortholog: z1115; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (380 aa) |
| | c1016 | Hypothetical protein; Residues 1 to 114 of 114 are 99.12 pct identical to residues 535 to 648 of 648 from GenPept.129 : >gb|AAG55261.1|AE005269_5 (AE005269) putative ATP-binding component of a transport system [Escherichia coli O157:H7 EDL933]. (114 aa) |
| | cydC | Transport ATP-binding protein cydC; Escherichia coli K-12 ortholog: b0886; Escherichia coli O157:H7 ortholog: z1230. (573 aa) |
| | cydD | Transport ATP-binding protein cydD; Escherichia coli K-12 ortholog: b0887; Escherichia coli O157:H7 ortholog: z1231. (588 aa) |
| | ftsK | Cell division protein ftsK; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA [...] (1347 aa) |
| | focA_2 | Probable formate transporter 1; Involved in the bidirectional transport of formate. Belongs to the FNT transporter (TC 2.A.44) family. (398 aa) |
| | msbA | Probable transport ATP-binding protein msbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (582 aa) |
| | ompF | Outer membrane protein F precursor; Porin ompF; Escherichia coli K-12 ortholog: b0929; Escherichia coli O157:H7 ortholog: z1276; Belongs to the Gram-negative porin family. (362 aa) |
| | pqiA | Paraquat-inducible protein A; Component of a transport pathway that contributes to membrane integrity. (417 aa) |
| | ompA | Outer membrane protein II*; Escherichia coli K-12 ortholog: b0957; Escherichia coli O157:H7 ortholog: z1307; Belongs to the outer membrane OOP (TC 1.B.6) superfamily. (379 aa) |
| | yccA | Hypothetical protein yccA; Escherichia coli K-12 ortholog: b0970; Escherichia coli O157:H7 ortholog: z1322. (219 aa) |
| | hyaC | Probable Ni/Fe-hydrogenase 1 B-type cytochrome subunit; Escherichia coli K-12 ortholog: b0974; Escherichia coli O157:H7 ortholog: z1391. (235 aa) |
| | putP | Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (502 aa) |
| | efeU | Putative cytochrome; Uptake of Fe(2+) ions across the membrane. Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family. (255 aa) |
| | ycdO | Protein ycdO; Involved in Fe(2+) uptake. Could be an iron-binding and/or electron-transfer component (By similarity); Belongs to the EfeM/EfeO family. (375 aa) |
| | ycdS | Hypothetical protein ycdS precursor; Escherichia coli K-12 ortholog: b1024; Escherichia coli O157:H7 ortholog: z1526. (807 aa) |
| | iroN | Siderophore receptor IroN; Residues 3 to 725 of 725 are 51.25 pct identical to residues 1 to 746 of 746 from MG1655 : b0584. (725 aa) |
| | csgG | Curli production assembly/transport component csgG precursor; May be involved in the biogenesis of curli organelles. Belongs to the CsgG family. (277 aa) |
| | csgF | Curli production assembly/transport component csgF precursor; May be involved in the biogenesis of curli organelles. (138 aa) |
| | csgE | Curli production assembly/transport component csgE precursor; May be involved in the biogenesis of curli organelles. (129 aa) |
| | mdoH | Periplasmic glucans biosynthesis protein mdoH; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs). (857 aa) |
| | yceE | Hypothetical transport protein yceE; Confers resistance to fosfomycin and deoxycholate. Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily. (408 aa) |
| | mviN | Virulence factor mviN homolog; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (511 aa) |
| | ptsG | PTS system, glucose-specific IIBC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II complex composed of PtsG and Crr is involved in glucose transport. Also functions as a chemoreceptor monitoring the environment for changes in sugar concentration. (477 aa) |
| | lolC | Lipoprotein releasing system transmembrane protein lolC; Part of an ATP-dependent transport system LolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of LolA (By similarity); Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily. (399 aa) |
| | potC | Spermidine/putrescine transport system permease protein potC; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (264 aa) |
| | potB | Spermidine/putrescine transport system permease protein potB; Escherichia coli K-12 ortholog: b1125; Escherichia coli O157:H7 ortholog: z1830. (287 aa) |
| | potA | Spermidine/putrescine transport ATP-binding protein potA; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (378 aa) |
| | nmpC | Outer membrane porin protein nmpC precursor; Escherichia coli K-12 ortholog: b0553; Escherichia coli O157:H7 ortholog: z2239; Belongs to the Gram-negative porin family. (380 aa) |
| | sitD | SitD protein; Residues 1 to 272 of 285 are 53.30 pct identical to residues 4 to 275 of 297 from SwissProt.40 : >sp|Q56955|YFED_YERPE Chelated iron transport system membrane protein yfeD. (285 aa) |
| | sitC | SitC protein; Residues 1 to 276 of 285 are 65.94 pct identical to residues 2 to 277 of 294 from SwissProt.40 : >sp|Q56954|YFEC_YERPE Chelated iron transport system membrane protein yfeC. (285 aa) |
| | sitB | SitB protein; Residues 7 to 263 of 275 are 62.03 pct identical to residues 11 to 276 of 296 from SwissProt.40 : >sp|Q56953|YFEB_YERPE Chelated iron transport system membrane protein yfeB. (275 aa) |
| | dsbB | Disulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by oxidizing the DsbA protein (By similarity); Belongs to the DsbB family. (178 aa) |
| | c1652 | Conserved hypothetical protein; Escherichia coli O157:H7 ortholog: z1966. (340 aa) |
| | narK | Nitrite facilitator 1; Escherichia coli K-12 ortholog: b1223; Escherichia coli O157:H7 ortholog: z2000. (465 aa) |
| | narG | Respiratory nitrate reductase 1 alpha chain; Escherichia coli K-12 ortholog: b1224; Escherichia coli O157:H7 ortholog: z2001; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1247 aa) |
| | narH | Respiratory nitrate reductase 1 beta chain; Escherichia coli K-12 ortholog: b1225; Escherichia coli O157:H7 ortholog: z2002. (512 aa) |
| | narI | Respiratory nitrate reductase 1 gamma chain; Escherichia coli K-12 ortholog: b1227; Escherichia coli O157:H7 ortholog: z2004. (225 aa) |
| | tonB | TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. (255 aa) |
| | ispZ | Probable intracellular septation protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family. (179 aa) |
| | pgpB | Escherichia coli K-12 ortholog: b1278; Escherichia coli O157:H7 ortholog: z2529. (254 aa) |
| | yciS | Hypothetical protein yciS; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. (102 aa) |
| | c1761 | Acriflavine resistance protein A precursor; Escherichia coli K-12 ortholog: b0463; Escherichia coli O157:H7 ortholog: z2509; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (384 aa) |
| | ycjV | Hypothetical ABC transporter ATP-binding protein ycjV; Escherichia coli K-12 ortholog: b1318; Escherichia coli O157:H7 ortholog: z2463; Belongs to the ABC transporter superfamily. (360 aa) |
| | ompG | Outer membrane protein G precursor; Escherichia coli K-12 ortholog: b1319; Escherichia coli O157:H7 ortholog: z2462. (318 aa) |
| | c1811 | Hypothetical protein; Residues 14 to 89 of 102 are 51.31 pct identical to residues 37 to 111 of 367 from GenPept.129 : >dbj|BAB49683.1| (AP003000) probable secretion protein [Mesorhizobium loti]. (102 aa) |
| | ydaN | Hypothetical protein ydaN; Mediates efflux of zinc ions; Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family. (327 aa) |
| | c1820 | Hypothetical protein; Residues 4 to 90 of 122 are 72.41 pct identical to residues 18 to 104 of 282 from GenPept.129 : >gb|AAL21744.1| (AE008830) Salmonella iron transporter: fur regulated [Salmonella typhimurium LT2]. (122 aa) |
| | cybB | Cytochrome b-561; Escherichia coli K-12 ortholog: b1418; Escherichia coli O157:H7 ortholog: z2303. (188 aa) |
| | ydcT | Hypothetical ABC transporter ATP-binding protein ydcT; Escherichia coli K-12 ortholog: b1441; Escherichia coli O157:H7 ortholog: z2278; Belongs to the ABC transporter superfamily. (337 aa) |
| | ydcU | Hypothetical ABC transporter permease protein ydcU; Escherichia coli K-12 ortholog: b1442; Escherichia coli O157:H7 ortholog: z2277. (313 aa) |
| | ortT | Hypothetical protein ydcX; Acts as an orphan toxin which is important for maintaining cell fitness during stress related to the stringent response. Increases the formation of persister cells. Has no known antitoxin. (82 aa) |
| | yddG | Hypothetical protein yddG; Escherichia coli K-12 ortholog: b1473; Escherichia coli O157:H7 ortholog: z2238. (293 aa) |
| | fdnH | Formate dehydrogenase-N beta subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (294 aa) |
| | fdnI | Formate dehydrogenase-N gamma subunit; Nitrate-inducible; Cytochrome b556 (FDN) subunit; Escherichia coli K-12 ortholog: b1476; Escherichia coli O157:H7 ortholog: z2234. (217 aa) |
| | yddB | Hypothetical protein yddB; CDS103; Escherichia coli K-12 ortholog: b1495; Escherichia coli O157:H7 ortholog: z2213. (790 aa) |
| | safA | Conserved hypothetical protein; Connects the signal transduction between the two-component systems EvgS/EvgA and PhoQ/PhoP, by directly interacting with PhoQ and thus activating the PhoQ/PhoP system, in response to acid stress conditions; Belongs to the SafA family. (65 aa) |
| | c1956 | Putative outer membrane protein yieC precursor; Escherichia coli K-12 ortholog: b3720. (557 aa) |
| | ydeD | Probable amino acid metabolite efflux pump; Escherichia coli K-12 ortholog: b1533; Escherichia coli O157:H7 ortholog: z2168. (306 aa) |
| | ynfJ | Putative chloride channel protein eriC-like; Probably acts as an electrical shunt for an outwardly- directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response; Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily. (438 aa) |
| | pntB | NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (462 aa) |
| | pntA | NAD(P) transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. (528 aa) |
| | ydgR | Hypothetical transporter ydgR; Proton-dependent permease that transports di- and tripeptides; Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily. (500 aa) |
| | ydiS | Probable electron transfer flavoprotein-quinone oxidoreductase ydiS; Part of an electron transfer system. Belongs to the ETF-QO/FixC family. (429 aa) |
| | ydiT | Ferredoxin-like protein ydiT; Could be a 3Fe-4S cluster-containing protein. (97 aa) |
| | btuD | Vitamin B12 transport ATP-binding protein btuD; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. (249 aa) |
| | btuC | Vitamin B12 transport system permease protein btuC; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity). (326 aa) |
| | ynjD | Hypothetical ABC transporter ATP-binding protein ynjD; Escherichia coli K-12 ortholog: b1756; Escherichia coli O157:H7 ortholog: z2788. (228 aa) |
| | sppA | Protease IV; Escherichia coli K-12 ortholog: b1766; Escherichia coli O157:H7 ortholog: z2799. (618 aa) |
| | manX | PTS system, mannose-specific IIAB component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport. Also functions as a receptor for bacterial chemotaxis and is required for infection of the cell by bacteriophage lambda where it most likely functions as a pore for penetration of lambda DNA. (323 aa) |
| | manY | PTS system, mannose-specific IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport. Also functions as a receptor for bacterial chemotaxis and is required for infection of the cell by bacteriophage lambda where it most likely functions as a pore for penetration of lambda DNA. (266 aa) |
| | manZ | PTS system, mannose-specific IID component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport. Also functions as a receptor for bacterial chemotaxis and is required for infection of the cell by bacteriophage lambda where it most likely functions as a pore for penetration of lambda DNA. (286 aa) |
| | htpX | Probable protease htpX; Escherichia coli K-12 ortholog: b1829; Escherichia coli O157:H7 ortholog: z2876; Belongs to the peptidase M48B family. (293 aa) |
| | yebS | Hypothetical protein yebS; Escherichia coli K-12 ortholog: b1833; Escherichia coli O157:H7 ortholog: z2880. (451 aa) |
| | yebT | Hypothetical protein yebT; Escherichia coli K-12 ortholog: b1834; Escherichia coli O157:H7 ortholog: z2881. (891 aa) |
| | nhaA | Na(+)/H(+) antiporter 1; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. (388 aa) |
| | lspA | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (164 aa) |
| | fixC | FixC protein; Could be part of an electron transfer system required for anaerobic carnitine reduction; Belongs to the ETF-QO/FixC family. (428 aa) |
| | fixX | Ferredoxin-like protein; Could be part of an electron transfer system required for anaerobic carnitine reduction. Could be a 3Fe-4S cluster-containing protein (By similarity). (95 aa) |
| | yabF | Putative NAD(P)H oxidoreductase yabF; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC; Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily. (176 aa) |
| | kefC | Glutathione-regulated potassium-efflux system protein kefC; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. (620 aa) |
| | ftsL | Cell division protein ftsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (121 aa) |
| | ftsW | Cell division protein ftsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (415 aa) |
| | ftsQ | Cell division protein ftsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. (276 aa) |
| | secA | Preprotein translocase secA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (901 aa) |
| | aroP | Aromatic amino acid transport protein aroP; Permease that is involved in the transport across the cytoplasmic membrane of the aromatic amino acids (phenylalanine, tyrosine, and tryptophan); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. (456 aa) |
| | gcd | Glucose dehydrogenase; Pyrroloquinoline-quinone; Escherichia coli K-12 ortholog: b0124; Escherichia coli O157:H7 ortholog: z0134. (802 aa) |
| | yadI | Putative PTS system IIA component yadI; Escherichia coli K-12 ortholog: b0129; Escherichia coli O157:H7 ortholog: z0140. (146 aa) |
| | folK | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Escherichia coli K-12 ortholog: b0142; Escherichia coli O157:H7 ortholog: z0153. (159 aa) |
| | mrcB | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (844 aa) |
| | yebM | High-affinity zinc uptake system ATP-binding protein znuC; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (251 aa) |
| | motB | Chemotaxis motB protein; Motility protein B; Escherichia coli K-12 ortholog: b1889; Escherichia coli O157:H7 ortholog: z2943. (308 aa) |
| | motA | Chemotaxis motA protein; Motility protein A; Escherichia coli K-12 ortholog: b1890; Escherichia coli O157:H7 ortholog: z2944. (295 aa) |
| | araH | High-affinity L-arabinose transport system; Escherichia coli K-12 ortholog: b1899; Escherichia coli O157:H7 ortholog: z2951; Belongs to the binding-protein-dependent transport system permease family. (329 aa) |
| | c2348 | Outer membrane porin protein nmpC precursor; Escherichia coli K-12 ortholog: b0553; Escherichia coli O157:H7 ortholog: z2239; Belongs to the Gram-negative porin family. (342 aa) |
| | emrE | EmrE protein; Methyl viologen resistance protein C; Escherichia coli K-12 ortholog: b0543; Escherichia coli O157:H7 ortholog: z1870. (170 aa) |
| | c2383 | Outer membrane protein N precursor; Porin ompN; Escherichia coli K-12 ortholog: b1377; Escherichia coli O157:H7 ortholog: z0302. (375 aa) |
| | c2436 | Putative pesticin receptor precursor; Similar to FyuA precursor [Yersinia pestis]; Residues 1 to 673 of 673 are 99.85 pct identical to residues 1 to 673 of 673 from SwissProt.40 : >sp|P46359|FYUA_YERPE Pesticin receptor precursor (IRPC). (673 aa) |
| | c2517 | Periplasmic binding protein; Residues 1 to 330 of 330 are 99.39 pct identical to residues 1 to 332 of 332 from GenPept.129 : >gb|AAL67368.1|AF447814_36 (AF447814) iron-chelating periplasmic-binding protein [Escherichia coli]. (330 aa) |
| | wcaJ | Putative colanic biosynthesis UDP-glucose lipid carrier transferase; Escherichia coli K-12 ortholog: b2047; Escherichia coli O157:H7 ortholog: z3211. (464 aa) |
| | c2586 | Tyrosine-protein kinase wzc; Escherichia coli K-12 ortholog: b2060; Escherichia coli O157:H7 ortholog: z3224. (732 aa) |
| | c2588 | Hypothetical protein; Residues 1 to 167 of 167 are 98.80 pct identical to residues 213 to 379 of 379 from GenPept.129 : >gb|AAG57122.1|AE005432_3 (AE005432) putative polysaccharide export protein [Escherichia coli O157:H7 EDL933]. (167 aa) |
| | c2589 | Putative conserved protein; Residues 1 to 211 of 214 are 99.52 pct identical to residues 1 to 211 of 379 from MG1655 : b2062. (214 aa) |
| | yegK | Hypothetical protein yegK; Escherichia coli K-12 ortholog: b2072; Escherichia coli O157:H7 ortholog: z3240. (253 aa) |
| | yegM | Hypothetical protein yegM precursor; The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (464 aa) |
| | yehX | Hypothetical ABC transporter ATP-binding protein yehX; Escherichia coli K-12 ortholog: b2129; Escherichia coli O157:H7 ortholog: z3378. (308 aa) |
| | yehZ | Hypothetical protein yehZ precursor; Escherichia coli K-12 ortholog: b2131; Escherichia coli O157:H7 ortholog: z3380. (305 aa) |
| | ccmF | Cytochrome c-type biogenesis protein ccmF; Escherichia coli K-12 ortholog: b2196; Escherichia coli O157:H7 ortholog: z3453. (647 aa) |
| | yojI | Hypothetical ABC transporter ATP-binding protein yojI; Escherichia coli K-12 ortholog: b2211; Escherichia coli O157:H7 ortholog: z3469. (547 aa) |
| | rcsC | Sensor protein rcsC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. (949 aa) |
| | elaB | ElaB protein; Escherichia coli K-12 ortholog: b2266; Escherichia coli O157:H7 ortholog: z3526; Belongs to the ElaB/YgaM/YqjD family. (101 aa) |
| | nuoN | NADH dehydrogenase I chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (485 aa) |
| | nuoM | NADH dehydrogenase I chain M; Escherichia coli K-12 ortholog: b2277; Escherichia coli O157:H7 ortholog: z3536. (509 aa) |
| | nuoL | NADH dehydrogenase I chain L; Escherichia coli K-12 ortholog: b2278; Escherichia coli O157:H7 ortholog: z3537. (613 aa) |
| | nuoK | NADH dehydrogenase I chain K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (100 aa) |
| | nuoJ | NADH dehydrogenase I chain J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I subunit 6 family. (184 aa) |
| | nuoI | NADH dehydrogenase I chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (180 aa) |
| | nuoH | NADH dehydrogenase I chain H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. (325 aa) |
| | nuoG | NADH dehydrogenase I chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity). (910 aa) |
| | nuoE | NADH dehydrogenase I chain E; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I 24 kDa subunit family. (166 aa) |
| | nuoB | NADH dehydrogenase I chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (220 aa) |
| | nuoA | NADH dehydrogenase I chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (147 aa) |
| | emrK | Multidrug resistance protein K; Escherichia coli K-12 ortholog: b2368; Escherichia coli O157:H7 ortholog: z3630. (387 aa) |
| | nupC | Nucleoside permease nupC; Transports nucleosides with a high affinity except guanosine and deoxyguanosine. Driven by a proton motive force. Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (413 aa) |
| | cysZ | CysZ protein; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family. (253 aa) |
| | crr | PTS system, glucose-specific IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II complex composed of PtsG and Crr is involved in glucose transport. (169 aa) |
| | cysA | Sulfate transport ATP-binding protein cysA; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (365 aa) |
| | cysW | Putative conserved protein; Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane. (291 aa) |
| | cysU | Sulfate transport system permease protein cysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (277 aa) |
| | cysP | Thiosulfate-binding protein precursor; Escherichia coli K-12 ortholog: b2425; Escherichia coli O157:H7 ortholog: z3690. (338 aa) |
| | uraA | Uracil transporter; Escherichia coli K-12 ortholog: b2497; Escherichia coli O157:H7 ortholog: z3760. (443 aa) |
| | yfgF | Hypothetical protein yfgF; Escherichia coli K-12 ortholog: b2503; Escherichia coli O157:H7 ortholog: z3766. (747 aa) |
| | yfgM | Hypothetical protein yfgM; Escherichia coli K-12 ortholog: b2513; Escherichia coli O157:H7 ortholog: z3776. (206 aa) |
| | yfgA | Hypothetical protein yfgA; Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis. (335 aa) |
| | yfhB | Hypothetical protein yfhB; Escherichia coli K-12 ortholog: b2560; Escherichia coli O157:H7 ortholog: z3840. (204 aa) |
| | lepB | Signal peptidase I; Escherichia coli K-12 ortholog: b2568; Escherichia coli O157:H7 ortholog: z3850; Belongs to the peptidase S26 family. (324 aa) |
| | yfiK | Hypothetical protein yfiK; Exporter of O-acetylserine (OAS) and cysteine; Belongs to the Rht family. (195 aa) |
| | gabP | GABA permease; 4-amino butyrate transport carrier; Escherichia coli K-12 ortholog: b2663; Escherichia coli O157:H7 ortholog: z3961. (487 aa) |
| | ygaP | Hypothetical protein ygaP; Escherichia coli K-12 ortholog: b2668; Escherichia coli O157:H7 ortholog: z3967. (174 aa) |
| | proV | Glycine betaine/L-proline transport ATP-binding protein proV; Escherichia coli K-12 ortholog: b2677; Escherichia coli O157:H7 ortholog: z3979. (400 aa) |
| | proW | Glycine betaine/L-proline transport system permease protein proW; Escherichia coli K-12 ortholog: b2678; Escherichia coli O157:H7 ortholog: z3980. (354 aa) |
| | proX | Glycine betaine-binding periplasmic protein precursor; Escherichia coli K-12 ortholog: b2679; Escherichia coli O157:H7 ortholog: z3981. (346 aa) |
| | ygaH | Hypothetical protein ygaH; Escherichia coli K-12 ortholog: b2683; Escherichia coli O157:H7 ortholog: z3984. (111 aa) |
